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      • KCI등재후보

        T 형 만성 림프구성 백혈병에 동반된 순수 적혈구 형성부전증 1 예

        곽재용,이홍,이미경,장재호,임창열,최삼임,송현모,최병문,박상석,이성중,조용곤,김윤정,이혜수 대한내과학회 1997 대한내과학회지 Vol.52 No.2

        Pure red cell aplasia(PRCA) is characterized by anemia, absence of reticulocytes in the peripherial blood and selective erythroid hypoplasia in the bone marrow. Acquired PRCA is often associated with thymoma but may also occur in many diverse conditions, such as chromic lymphocytic leukemia, systemic lupus erythematosus, autoimmune disorders, T gamma lymphocytosis, acquired hypogammaglobulinemia, acquired immunodeficiency syndrome. Recently we experienced a case of T cell chronic lymphocytic leukemia associated with pure red cell aplasia. A 65-year-old man was presented with severe anemia. absolute reticulocytopenia, hepatosplenomegaly and lymphocytosis(T cell marker' CD2, CD7 positive). Bone marrow findings showed a marked decrease in erythroid precursors and normal maturations of granulocytic and megakaryocytic series, which were consistent with pure red cell aplasia. So we report this case with a review of the literature.

      • SCOPUSKCI등재

        액체 Silicone과 Paraffin의 주입후 나타난 색전현상의 증례

        곽승호,이삼용,조백현,임기영 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.5

        The infection of liquid silicone or paraffin for cosmetic purposes has been an unfavorable method with such complications as development of granulomas, migration of the foreign body, inflammation, ulceration, embolic phenomena and etc. However, these materials have been used by some unauthorized people for augmentation os the soft tissue in such areas as the face and breasts for they can easily transform the body contour in a short period and are inexpensive to do so,. We experienced the unusual cases of visual loss and respiratory difficulty after injection of liquid silicone or paraffin subcutaneously in the face and chest. Three patients lost their vision immedately after injection of these materials in the face, and one patient underwent respiratory difficulty following injection of liquid silicone in the chest. Among the three facial cases, one was observed without treatment, the other was treated by secondary intention with antibiotics, and the third case was operated on to remove the foreign body from the nose. The saddle nose deformity after removal of nasal foreign body was treated by means of insertion temporalis fascia-wrapped silastic implant. Visual loss was irreversible. Dyspnea of the chest case disappeared after two weeks of steroid therapy. The cause of these disastrous complications was believed to be occlusion of vessels with the emboli inadvertently injected into the vascular channel.

      • KCI등재

        품행장애 청소년의 도덕적 정서

        곽승철,임시순 한국정서.행동장애아교육학회(구.한국정서학습장애아교육학회) 2003 정서ㆍ행동장애연구 Vol.19 No.4

        In view of conduct-disordered adolescents's moral development, this study aims first to suggest three hypotheses for conduct-disordered adolescents and adolescents, and in morally violent circumstances to compare offender's moral emotions to that of victim. Second, this study aims to compare conduct-disordered adolescents's moral attributions with adolescents. The objects for this study are thirty conduct-disordered adolescents classified on the basis of DSM-Ⅳ(1994) standards and thirty ordinary ones. They are chosen from three middle school and three high school respectively and their ages are ranged from fifteen to seventeen, that is, born from in 1985 to in 1987. In this study, interviews were implemented to find out a variety of moral emotions and moral attributions on moral emotions and attributions. The data were analyzed by chi-squares to examine conduct-disordered adolescents and normal adolescents in a position of offender to that in a position of victim suggested by three hypotheses concerning morally violent behavior. This study is summarized as follows : First, there appears differences in moral emotions in a position offender between conduct-disordered adolescents and normal adolescents. The former is revealed to have more emotions of pleasure, while the latter has more emotions of regret and guilt. Second, regarding the result of moral emotions in a position of victim, normal adolescents's group expressed mostly indignant, while conduct disordered adolescents's group expressed mostly embarrassed or scared rather than indignant brought by properly sympathized response. Third, with regard to moral sentimental reversion in a position of offender, normal adolescents show their moral attributions which relates to profit and loss on products. In contrast, conduct-disordered adolescents were found it relatively low due to moral reason relating to equality and fairness. Moreover, they show their tendency to attributed relatively high due to outcome and emotional distancing. Fourth, concerning moral attributions in a position of victim, for normal adolescents, moral attributions relating to equality and fairness accounts for the highest proportion. Meanwhile, for conduct-disordered adolescents's group, the empathized attributions which have common emotion with the character of the given situation account for the highest proportion. In addition, normal adolescents is higher than conduct-disordered adolescents for the proportion to explain by moral reason.

      • Poster Session:PS 0240 ; Gastroenterology : Benign Prostatic Hyperplasia Mimicking a Rectal Subepithelial Tumor: A Case Report

        ( Seung Wook Hong ),( Jae Young Chun ),( Jong Pil Im ),( Cheol Kwak ),( Kyu Joo Park ),( Joo Sung Kim ),( Hyun Chae Jung ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Benign prostatic hyperplasia (BPH) is the most common tumor in men, and the prevalence of BPH increases with age. BPH commonly presents with obstructive and irritative lower urinary tract symptoms including weak urinary stream, hesistancy, incomplete voiding, nocturia, urgency, and frequency. However, gastrointestinal manifestations due to extrinsic compression of the anterior rectum are very rare in patients with BPH. We report the case of a 56-year-old man with a prostatic mass extending into the rectal mucosa. He underwent surgical ablation for a 5 cm-sized benign subepithelial cystic mass in the rectum, which was adjacent to a 5 cm-sized solid mass located at the prostatic gland on a computed tomography (CT) and magnetic resonance imaging (MRI) of the pelvis. At 1 year after the surgery, he had anal bleeding with diffi culty in defecation. The pelvis MRI scan demonstrated no signifi cant interval change in size of the heterogenous solid mass with enhancement compressing the rectum. However, the sigmoidoscopic exam showed a 4 cm-sized mass protruding through the anterior rectal mucosa above 7 cm from anal verge. Ultra-low anterior resection with ileostomy and prostatectomy was performed for curative resection of the mass with extension into the rectum. Pathologic reports revealed massive benign prostatic hyperplasia, not penetrating into but involving the rectum. This is the fi rst case of benign prostatic mass mimicking a rectal subepithelial mass in a patient presented with anal bleeding and constipation.

      • Series of Liquid Separation System Made of Homogeneous Copolymer Films with Controlled Surface Wettability

        Kwak, Moo Jin,Oh, Myung Seok,Yoo, Youngmin,You, Jae Bem,Kim, Jiyeon,Yu, Seung Jung,Im, Sung Gap American Chemical Society 2015 Chemistry of materials Vol.27 No.9

        <P>Exquisite surface wettability control of separation system surface is required to achieve separation of liquids with low surface tension difference. Here, we demonstrate a series of surface-energy-controlled homogeneous copolymer films to control the surface wettability of polyester fabric, utilizing a vapor-phase process, termed as initiated chemical vapor deposition (iCVD). The homogeneous copolymer films consist of a hydrophobic polymer, poly(2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane), pV4D4, and a hydrophilic polymer, poly(4-vinylpyridine), p4VP. Because the mixing of two or more components is always favorable in vapor phase, the iCVD process allows the formation of homogeneous copolymers from two immiscible, hydrophilic/hydrophobic monomer pairs, which is highly challenging to achieve in liquid phase. Simply by tuning the flow rate ratio of monomer pairs, a series of homogeneous copolymers with systematically controlled surface energy were formed successfully. The fabricated separation system could separate water (surface energy = 72.8 mJ/m<SUP>2</SUP>), glycerol (64 mJ/m<SUP>2</SUP>), ethylene glycol (48 mJ/m<SUP>2</SUP>), and olive oil (35.1 mJ/m<SUP>2</SUP>) sequentially with excellent selectivity, just by choosing a copolymer-coated polyester fabric with proper surface energy. Considering the small differences in the surface tension of the liquids used in this work, the surface-energy-controlled separation system can be a powerful tool to separate various kinds of liquid mixtures.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cmatex/2015/cmatex.2015.27.issue-9/acs.chemmater.5b00842/production/images/medium/cm-2015-00842c_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cm5b00842'>ACS Electronic Supporting Info</A></P>

      • SCOPUSKCI등재
      • KCI등재

        Pilot Study: Effects of Acupuncture on the Muscle Cramps of Liver Cirrhosis Patients

        Kim, Seung-mo,Kwak, Min-ah,Joo, Jeong-hyun,Kim, Kyung-soon,Shin, Im-hee,Lee, Chang-hyeong The Society of Internal Korean Medicine 2018 大韓韓方內科學會誌 Vol.39 No.3

        Objective: The purpose of this clinical trial is to examine the efficacy and safety of electroacupuncture on liver cirrhosis patients suffering from muscle cramps. Methods: A total of 14 liver cirrhosis patients with muscle cramps were treated by electroacupuncture three times a week for four weeks (12 times total). The electrical stimulation was a frequency of 100 Hz. Evaluation of the muscle cramps was measured by a questionnaire of subjective symptoms. The patients' condition was evaluated four times over a period of eight weeks. We also assessed the deterioration of liver disease using the Child-Pugh score and blood tests. Results: This study proves that four weeks of electroacupuncture treatment is effective in reducing the frequency of muscle cramps and that the effects of electroacupuncture treatment lasted during another four-week follow-up period after treatment. Conclusions: This study suggests that electroacupuncture treatment is beneficial for improving muscle cramps in liver cirrhosis patients (p=0.000). Electroacupuncture is thought to be a safe treatment for liver cirrhosis patients with muscle cramps without contributing to the worsening of liver function. Further study with a larger sample size is needed to confirm our findings.

      • Increased Apoptosis in Pig Parthenogenetic Fetuses Resulting Fetal Degeneration during Early Gestation Period

        In-Sul Hwang,Seung-Chan Lee,Tae-Uk Kwak,Mi-Ryung Park,Sun-A Ock,Keon Bong Oh,Jae-Seok Woo,Gi-Sun Im,Seongsoo Hwang 한국동물생명공학회(구 한국동물번식학회) 2017 발생공학 국제심포지엄 및 학술대회 Vol.2017 No.10

        Parthenogenetic embryo without contribution of paternal genome would be terminated during early gestation period in pigs. Therefore, the present study was designed to analyze the characteristics of parthenogenetic fetuses to identify the possible causes for fetal degeneration during early gestation period. In brief, the pig parthenogenetic fetuses were produced by embryo transfer of parthenogenetic embryos into surrogates. Then, the pig parthenogenetic fetuses were recovered at day 26 and 35 of gestation and conducted to analyze histological characteristics. In results, the parthenogenetic pig fetuses were generated and recovered at day 26 and 35 successfully. The size of parthenogenetic fetuses (n=15, 1.5 cm) recovered at day 26 of gestation were significantly smaller than normal fetuses (n=18, 2.0 cm) while the weights were comparable (0.36 vs. 0.51 g). The size and weight of parthenogenetic fetuses (n=9, 1.8 cm, 0.47 g) recovered at day 35 of gestation were significantly lower than normal fetuses (n=3, 3.67 cm, 3.71 g). The paraffin-embedded sections from parthenogenetic fetus at day 26 showed normal formation of major organs while parthenogenetic fetus at day 35 showed terminated and degenerated formation of major organs. Additionally, the apoptotic cell number of parthenogenetic fetuses (4.4) recovered at day 35 of gestation were significantly (p<0.05) higher than normal fetuses (2.0) while the result of day 26 of gestation showed comparable (1.8 vs. 2.0). Conclusively, our results can suggest that increased apoptosis in fetal tissues also leads to abnormal development of parthenogenetic pig fetus resulting delayed development until day 26 and then termination and degeneration from day 36.

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