인슐린 비의존형 당뇨병 환자에 있어서의 체중변화에 관한 연구

이현철,허갑범,임승길,김현만,조준구,황용 대한당뇨병학회 1986 Diabetes and Metabolism Journal Vol.10 No.1

Dodeyl diamino thyi glycin hydrochloride(Hygien 51)의 각종항산균에 대한 항균작용에 관한 시험관내 실험

황청자,진재신,김주덕,오흥근 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1

In order to prevent cross-infection, the sterilization of used and/or contaminated anesthetic- apparatus is still a difficult problem in clinical practice, particularly, following anesthesia for known advanced pulmonary tuberculosis cases. Therefore the antibacterisl activities of, an amphoteric detergent, Dodecyl diaminoethyl glycin hydrochloride (Hygien 51) were tested in vitro as a disinfectant against mycobacteria (M. tuberculosis H37 Rv, M. bovis, M. avium, M. tuberculosis H37 Ra, M. phlei, B.C.G.) The antimycobacterial activity tests were perfomed according to the modified Kolmer method. The testing organisms were cultured in Dubos broth at 37°C, and the detergent, Hygien 51, was: diluted with sterile distilled water to 1,3,5 and 10%. One half milliliter of culture was pipetted into each tube containing 4.5 ml of diluted detergent, and at intervals of 3, 15, 30, 60, 120, 180 and 240 minutes, a 4mm loopful of the material was removed from each tube, and transferred to Ogawa media. The tests were carrid out at two different temperatures, 20°C and 50°C. The subcultures were incubated at 37°C for more than 8 weeks. The results were obtained as follows: 1) At room temperature (20°C), all mycobateria, except M. bovis, were destroyed by treatment- with 10% solution of the detergent for more than 60 minutes. M. bovis was relatively sensitive to the detergent, and was killed by 5% solution for 30 min. and 10% for 15 min., but M. avium. was very resistant, and was not killed by 10% solution for 240 min. 2) By treatment with the detergent at 50°C, the antimycobacterial activities of the detergent were highly increased. All mycobacteria were destroyed by 1% solution for 180 min, and by 10% for less than 30 min at 50°C. In the comparison of the antibacterial activities against mycobacteria and other bacteria, it shows that mycobacteria are generally more resistant to the detergent, Hygien 51.

소 결합 환경에서 순환 질의 처리를 위한 형판 연산기법

황규영(Kyu-Young Whang),홍기형(Ki-Hyung Hong),이윤준(Yoon-Joon Lee) 한국정보과학회 1991 정보과학회논문지 Vol.18 No.3

본 논문에서는 소 결합 환경하에서 순환 질의의 한 부류를 효율적으로 처리하기 위한 template 처리 기법을 제안하고, 그 정당성을 증명하였다. Template 처리 기법은 주 기억장치내의 릴레이션과 이차 기억장치에 저장되어 있는 릴레이션 사이의 비용이 비싼 결합 연산(join)을 완전히 제거함으로써 순환 질의를 효과적으로 처리한다. 본 기법으로 처리할 수 있는 질의의 부류는 Whang과 Navathe가 제안한 확장된 논리합 정규형(extended disjunctive normal form)으로 표현하였을 때, 하나의 비환형 트리(nonlooped-tree)와 하나의 단일환형 트리(single looped tree)로 표현된다. We present the template evaluation technique for efficient processing of a class of recursive logic queries in a loosely-coupled environment. Using this technique, queries are evaluated efficiently by avoiding costly joins between an in-memory relation residing in main memory and a database relation residing in the secondary storage. The queries in this class are those represented by one nonlooped tree and one single-looped tree (indicating linear recursion) in the extended disjunction normal form proposed by Whang and Navathe. We also prove the correctness of the template evaluation technique.

A Study on the Symmetric and Antisymmetric Charge Transfer

Whang, C.N,Chin, W.B. 東國大學校 附設 材料科學硏究所 1981 材料科學硏究所 論文集 Vol.1 No.-

본 연구에서는 對稱 및 比對稱 電荷變換에 대한 Rapp와 Francis의 理論을 유효 이온화 에너지와 충격인자를 사용하여 개량하였으며, 理論式을 Perel 및 C.N. Whang의 실험결과와 비교해 본 결과 잘 일치함을 알 수 있었다. 대칭 전하 변환과정에서 임자이온의 에너지가 증가함에 따라 단면적이 감소하며, 비대칭 변환과정에서 임사이온의 속도가 증가함에 따라 단면적이 감소한다.

일일 주식가격에 대한 카오스 검정

백웅기(Ehung Gi Baek),황윤재(Yoon Jae Whang) 한국경제학회 1999 經濟學硏究 Vol.47 No.2

1980년대 중반 이후 경제학 문헌에서는 경제자료의 동태적 성질이 카오스적 특성을 가질 수 있다는 가능성에 대해 학자들의 많은 관심이 집중되어 오고 있다. 그러나 경제자료에 있어서 카오스적 특성의 경험적 존재 여부에 관해서는 학자들의 견해가 일치하지 않는다. 이러한 견해불일치의 가장 근본적 이유는 얼마 전까지만 해도 카오스존재를 직접적으로 검정할 수 있는 방법이 개발되지 않았다는 데 있다 본고는 카오스의 존재를 직접 검정하기 위하여 최근 개발된 Whang-Linton방법을 종합주가지수를 비롯한 20종의 일일 주식가격에 적용함으로써 주식시장에서 카오스의 존재를 검정하였다. BDS통계량을 비롯한 간접검정법은 일부 종목별 주식가격의 비선형성을 시사한 바 있으나, 직접검정법인 Whang-Linton법은 종합주가지 수를 비롯한 모든 대상종목에 카오스적인 증거가 없다는 사실을 입증하였다.

Molecular Analysis of Anthocyanin Biosynthetic Genes and Control of Flower Coloration by Flavonoid 3',5'-Hydroxylase (F3'5'H) in Dendrobium moniliforme

Whang, Sung-Soo,Um, Wan-Sook,Song, In-Ja,Lim, Pyung-Ok,Choi, Kyung,Park, Kwang-Woo,Kang, Kyung-Won,Choi, Mi-Sun,Koo, Ja-Choon 한국식물학회 2011 Journal of Plant Biology Vol.54 No.3

Dendrobium moniliforme is a native species of Korea. The flower of this species is composed of a reproductive column and white perianths including petals, sepals and lip, but the base of the column bears reddish purple pigment spots. Anthocyanins are major pigments that contribute flower color in Dendrobium. Three key anthocyanin biosynthetic genes encoding dihydroflavonol 4-reductase (DFR), chalcone synthase (CHS), and flavonoid 3',5'-hydroxylase (F3'5'H) were isolated and analyzed for their expression patterns in floral organs to understand the molecular mechanism underlying flower color development. Quantitative RT-PCR analysis revealed that F3'5'H transcripts were highly accumulated in the base of the column compared with those of perianths, but the other two genes showed no significant difference among the floral organs. Microprojectile bombardment using the white perianths revealed that the transient expression of F3'5'H gene, but not DFR and CHS genes, was sufficient to produce reddish purple colored pigmentation. These results suggest that the lack of colors in perianths of D. moniliforme is at least due to transcriptional control of F3'5'H. The data presented here may improve our understanding of the mechanisms underlying floral color development in D. moniliforme and contribute to advances in orchid biotechnology.

Metabolic Discrimination of Safflower Petals of Various Origins Using ¹H NMR Spectroscopy and Multivariate Statistical Analysis

Whang, Wan-Kyun,Lee, Min-Won,Choi, Hyung-Kyoon Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.4

The metabolic discrimination of safflowers from various geographical origins was performed using 1H nuclear magnetic resonance (NMR) spectroscopy followed by principal components analysis. With a combination of these techniques, safflower samples from different origins could be discriminated using the first two principal components (PC) of the 1H NMR spectra of the 50% methanol fractions. PC1 and PC2 accounted cumulatively for 91.3% of the variation in all variables. The major peaks in the 1H NMR spectra that contributed to the discrimination were assigned to fatty acid (terminal CH3), lactic acid, acetic acid, choline derivatives, glycine, and safflower yellow derivatives. In this study, we suggest that various types of safflower can be discriminated using PCA and 1H NMR spectra.

Morphological and molecular characterization of Pseudocohnilembus longisetus Thompson, 1965 from farmed black rockfish Sebastes schlegelii in Korea

Whang, I.,Kang, H.S.,Lee, J. Elsevier Scientific Pub. Co 2011 Veterinary parasitology Vol.179 No.1

The morphology, infraciliature, silverline system, and the small subunit ribosomal RNA (SSU rRNA) of the little-known marine scuticociliate Pseudocohnilembus longisetusThompson, 1965 from the diseased black rockfish Sebastes schlegelii in Korea were studied. This scuticociliate possessed the typical characteristics of the genus Pseudocohnilembus, but could be discriminated from Pseudocohnilembus hargisi, and Pseudocohnilembus persalinus in terms of the body size, shape, the number of somatic kineties and kinetids in somatic kinety 1, and the number/position of contractile vacuole pores. The SSU rRNA gene of P. longisetus was sequenced in order to gain a better understanding of appropriate phylogenetic classification. The SSU rRNA was 1754bp and the sequence was deposited in GenBank under accession number FJ899594. The SSU rRNA gene sequences of P. longisetus had an identity of 98.1%, 96.8% and 95.3% with P. hargisi, P. persalinus, and Pseudocohnilembus marinus SSU rRNA sequences, respectively. Our population of P. longisetus belonged to the genus Pseudocohnilembus and was in an isolated position based on the SSU rRNA gene tree, which was consistent with the conclusions based on the morphological studies. However, further investigation is required to determine the pathogenicity of this species.

The Prevalence of Human Papillomavirus Type 16 in the Healthy Normal Women

Whang, Jung Hae,Cho, Sam Hhun,Moon, Hyung,Kim, Doo Sang 한양대학교 의과대학 1992 한양의대 학술지 Vol.12 No.1

현재까지 분류된 60여종의 Human papillovavirus(HPV) 중 16형은 자궁경부암환자에서 가장 흔히 구명되는 유형이기 때문에 임상가에서는 임의적으로 고위험군으로 분류되고 있다. 그러나 아직까지 HPV가 과연 자궁경부암을 위시한 여성 성기암의 원인인자로 작용하는지는 역학적으로 유보상태이다. 따라서 자궁경부의 상피세포에 아무런 변화를 초래하지않은 정상인에서의 발현연구는 HPV의 암 유발인자로의 역할을 해석하는데 주요한 의미를 내포하기 때문에 본 저자는 1989년 한양대학병원 부인과 외래에 자궁암 검진을 받고자 내원한 여성중 세포진, 질확대경 및 조직검사 결과중 HPV 감염증거인 koilocytosis와 세포핵이상의 어느 한 특징도 발견되지 않은 34명의 조직절편을 재료로하여 HPV검출에 가장 객관성을 인정받는 Southern blot hybridization으로 일차 발현도를 구한다음 이에 음성인 전예를 대상으로 HPV 유전자중 가장 보존적인 E1, E6 절편에 위치한 nucleotides를 선정, 합성하여 핵산연쇄증폭방법으로 그 위음성을 확인하였다. Southern blot hybridization으로 구명된 양성율은 6%(2/34)이었으며 음성이었던 32예중 18예(56%)가 핵산연쇄증폭방법으로 양성으로 판명됨에 따라 전체 발현율은 59%(20/34)로 증가되었다. HPV 감염은 성병력, 불임여부 및 피임방법, 기왕의 임신력과 무관하였으며 연령이 증가할 수록 높은 발현율을 보이나 통계적 의의는 인정되지 않았고 3년 추적기간동안 이형성 이상으로 발전된 병소는 한 예도 관찰되지 않았다. 따라서 HPV 연구시 Southern blot이나 다른 방법으로의 구명이 음성이라 하드라도 반드시 핵산연쇄 증폭으로 그 위음성을 확인하여야 하며 감염촉진인자와의 상호 보완영향과 자궁경부에 존재하는 HPV 가 병원체로의 확증을 얻기위하여서는 보다 큰 대집단에서의 연구가 실행되어야하리라 사료된다.

CHI-SQUARE DIAGNOSTIC TESTS FOR DYNAMIC ECONOMETRIC MODELS

Whang, Yoon-Jae 梨花女子大學校 法政大學 1994 社會科學論集 Vol.14 No.-

This paper extend the Pearson chi-square testing method to dynamic parametric econometric models with covariates. The paper establishes the limit distribution of the test statistic under the null and proves consistency of the tests when the test statistic is based on data-dependent random cells of a general form and on an arbitrary asymptotically normal estimator. The results are obtained by utilizing the general framework of specification tests suggested by Whang and <참고문헌참조 actuate="onRequest" inline="true" rid="ref8" show="replace" xml:link="simple">Andrews (1993)</참고문헌참조>.