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      • 노년기 재혼에 관한 질적 연구 : 재혼한 노인을 대상으로

        박충선,배나래 대구대학교 사회복지연구소 2003 社會福祉硏究 Vol.24 No.-

        급속한 경제성장으로 인한 의학 기술의 발전과 식생활 개선은 노인들의 평균수명의 연장 시켰다. 또한 노년기 연장은 홀로 살아가는 노인의 수를 증가 시켰다. 이러한 홀로된 노인들은 배우자 상실로 인한 정신적 고독과 심리적 외로움을 많이 겪고있으며, 전근대적인 사고를 가진 노인들과 진취적이고 개방적인 사고를 가진 성인자녀와의 가치관 차이에서 파생되는 문제로 인해 많은 내적·외적갈등과 어려움을 겪고 있다. 이와 같은 고독과 외로움, 성인자녀와의 갈등은 부부가 같이 거주하는 노인보다 홀로된 노인에게 더 많은 문제로 나타나기 시작했다. 이러한 홀로 사는 노인들의 내적 외적문제를 해결하는 하나의 방안으로 노년기재혼을 제시하고자 한다. 홀로된 노인들의 남은 여생에서 행복한 노년기를 영위하기위해서는 가족들의 관심과 사회의 적절한 개입·지원을 필요로 하게 되지만 우리나라는 아직 노인의 재혼에 대한 필요성은 강조되는 반면 실질적인 방안마련은 미흡한 하다고 할 수 있다. 본 연구는 재혼한 노인들의 대상으로 그들의 특성과 재혼의 동기, 재혼의 성립과정, 재혼 후 가족관계, 재혼에 관한 견해를 인터뷰를 통해 분석하여 재혼한 노인들의 사실적인 경험을 바탕으로 한 전반적인 노년기 재혼의 실태를 파악하는데 그 목적 이 있다 The purpose of this study is to increase the understanding of a married couple's relationship and remarriage in old age and to help old people who want to be advised about their remarriage as a coping response of life for widowhood in old age. The subjects were 10 men and 10 women who remarried over 55 years old after bereavement and divorce residing in Daegu and Gyeongbuk areas, and data were collected through depth interviews. The bereaved old people and divorced old people chose remarriage as a coping response of their loneliness. They understand and concede each other, and they maintain mental relations with their own children and keep minimum contact with children of a new spouse. It means they make efforts minimize troubles and stain. And these old people are contented with their life reducing or removing loneliness before remarriage. So, the remarriage in old age can be regarded as a coping type for the old who became alone. And most of emotional problems are resolved by the remarriage of the old. Therefore we need to help the widowed elderly to overcome loneliness and to live a good life for the rest of their life by grasping or understanding their desires

      • KCI등재
      • 전격성 제1형 당뇨병 1예

        노동현,김도형,김나래,박종선,이창헌,김미경,최영식 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

        전격성 제1형 당뇨병은 특발성 당뇨병환자에서 임상 경과가 짧고 진단 당시 심각한 대사 합병증을 동반하면서 췌장 효소 수치가 높고 췌도 특이 자가항체가 음성인 새로운 아형으로 알려져 있으며, 일본과 일본 외에서의 유병률에는 차이가 있는 것으로 보인다. 아직 전격성 제1형 당뇨병의 발생 기전은 명확하지 않으며 유전적 감수성이 있는 개체에서 바이러스 감염 등의 환경적인 인자와의 연관성이 가능한 병태생리로 제시되고 있으며 이에 대한 추가적인 연구가 요구된다. 저자들은 케톤산증으로 내원하여 전격성 제1형 당뇨병을 진단받은 증례를 경험하였기에 문헌고찰과 함께 보고 하는 바이다. Some patients with idiopathic type 1 diabetes have a fulminant disorder characterized by the absence of insulitis and of diabetes-related antibodies, a remarkably abrupt onset and high serum pancreatic enzyme concentrations. This is referred to as fulminant type 1 diabetes. A 29-year-old man suffering from abdominal pain, nausea and vomiting consulted to our hospital. Laboratory findings revealed high blood glucose level and the evidence of diabetic ketoacidosis, but the serum HbA1c was normal nevertheless. The low level of plasma C-peptide indicated the loss of endogenous insulin secretion. The patient satisfied the criteria for the diagnosis of fulminant type 1 diabetes. After the patient has been treated with insulin, his symptoms were improved and abnormal laboratory data were normalized. We report this case with a review of the literature

      • KCI등재

        땅콩나물 뿌리 추출물의 세포 보호 효과

        조나래 ( Na Rae Jo ),박찬일 ( Chan Il Park ),박채원 ( Chae Won Park ),신동한 ( Dong Han Shin ),황윤찬 ( Yoon Chan Hwang ),김용현 ( Yong Hyun Kim ),박수남 ( Soo Nam Park ) 한국공업화학회 2012 공업화학 Vol.23 No.2

        본 연구에서는 땅콩나물 뿌리 추출물의 세포보호 작용 및 항산화능에 관한 연구를 수행하였다. Rose-bengal로 증감된 사람 적혈구의 광용혈에 대한 땅콩나물 뿌리 추출물의 세포 보호 효과를 측정하였다. 에틸아세테이트 분획(5~50 μg/mL)은 농도-의존적으로 세포보호 효과를 나타냈으며, 특히 아글리콘(aglycone) 분획은 5~50 μg/mL의 농도 범위에서 현저한 세포보호 활성을 나타내었다. 그리고 땅콩나물 뿌리의 모든 분획은 지질 과산화 연쇄반응의 차단제인 (+)-α-tocopherol보다도 효과적이었다. Luminol 화학발광법을 이용한 Fe3+-EDTA/H2O2 계에서 생성된 활성산소종(reactive oxygen species, ROS)에 대한 땅콩나물 뿌리 추출물의 활성산소 소거활성을 측정하였다. 추출물 중 에틸아세테이트 분획(OSC50; 1.59 μg/mL)은 강력한 항산화제로 알려진 L-ascorbic acid (1.50 μg/mL)와 비교할 때 유사한 활성산소 소거활성을 보여주었다. 반면에, free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) 소거활성(FSC50)의 크기는 (+)-α-tocopherol > 80% MeOH 추출물 > 아글리콘 분획 > 에틸아세테이트 분획 순으로 나타났다. 이상의 결과들은 땅콩나물 뿌리 추출물이 1O2 및 다른 활성산소종을 소거하고 활성산소종에 대항하여 세포막을 보호함으로써 생체계, 특히 태양 자외선에 노출된 피부에서 항산화제로써 작용할 수 있음을 시사한다. In this study, the cellular protective effect and antioxidative property of peanut sprout root extracts were investigated. Cellular protective effects of peanut sprout root extracts on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The ethyl acetate fraction of extracts exhibited a cellular protective effect in a concentration dependent manner. Particularly, the aglycone fraction of extracts showed prominent cellular protective effects in a concentration range (5~50 μg/mL). They are more effective than that of (+)-α-tocopherol, known as a lipid peroxidation chain blocker. Reactive oxygen species (ROS) scavenging activities (OSC50) of peanut sprout root extracts on ROS generated in Fe3+-EDTA/H2O2 system were investigated using the luminol-dependent chemiluminescence assay. The ethyl acetate fraction of extracts (OSC50; 1.59 μg/mL) showed a similar ROS scavenging activity compare with that of L-ascorbic acid (1.50 μg/mL), known as a strong antioxidant. On the other hand, the order of free radical (1,1-diphenyl-2-picrylhydraxyl, DPPH) scavenging activity (FSC50) was (+)-α-tocopherol > 80% MeOH extract > aglycone fraction > ethyl acetate fraction. These results indicate that peanut sprout root extracts can function as an antioxidant in biological systems, particularly skin exposed to solar UV radiation by scavenging 1O2 and other ROS, and to protect cellular membranes against ROS.

      • KCI등재

        초등학생의 생물 개념 이해를 위한 다시 읽기 학습법의 효과 -안구 운동을 중심으로-

        박나래 ( Na Rae Park ),신동훈 ( Dong Hoon Shin ) 韓國生物敎育學會 2016 생물교육 Vol.44 No.2

        The purpose of this study was to analyze the effectiveness and accuracy of students’ understanding of a material through the use of the repeated learning strategy. An eye tracking device was used to report the data. The material used for this was an extract taken from a second semester sixth grade science textbook based off the new 2009 curriculum. The passages were taken from the third section of the first chapter entitled “Living Organisms and Our Lifestyle”. The sample students were eight sixth grade students and seven fifth grade students from G elementary school. The students were split into three groups with equal abilities after having conducted a pre-evaluation test. After the groups had been formed, they were given three passages from the textbook relating to “Mould and Mushrooms”, “Spirogyra and Paramecium” and “Bacteria”. To test their understanding, they were then asked to try and answer nine questions about the text they had just read. As a result, this study can support the argument that it is advantageous to read a piece of writing three times in order to increase their understanding. The process of rereading leads to reduced number of fixation, fixation duration, number of regression, and number of regression. In particular, if the reader feels that the importance of a sentence is low then the number of fixation can be considerably reduced. When students reread were found to selectively read the target text, with their level of understanding varying depending on their recognition of the text’s importance and how much useful information could be found therein. Furthermore, students found rereading in education to be useful to their studies and were seen to have a positive attitude in following directions to do it.

      • KCI등재

        Difference In Serum Nephrin Expression Between Normal And Preeclamptic Pregnancies; A Preliminary Study

        ( Bit Na Rae Kim ),( Ja Young Kwon ),( Ye Jin Park ),( Myung Hwa Kang ),( Jong Rak Choi ),( Young Geun Kwon ),( Young Han Kim ),( Yong Won Park ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.8

        Objective Nephrin is one of the slit membrane proteins of podocytes in the kidney. It is known that the nephrin is shed in the urine in nephropathy accompanying proteinuira. So the aim of this study was to evaluate the difference in the serum nephrin expression between normal and preeclamptic pregnancies. Methods A total of 20 pregnant women from May to September 2008 who received prenatal care and underwent delivery at our institute participated in the study. The preeclamptic group includes 13 women diagnosed as preeclampsia and a normal group of 7. Their serum were collected before delivery and analyzed by Western blotting for comparing serum nephrin expression. Results There was no difference in age, body weight of pregnant women, blood urea nitrogen, serum creatinine, urine creatinine level and gestational age between two groups. However, preeclampsia group had significantly higher systolic and diastolic blood pressure ( P<0.001), serum soluble fms-like tyrosine kinase-1 level ( P= 0.002), and lower birth weight ( P=0.011). In serum Western blot analysis, serum nephrin was detected in 10 of 13 in preeclampsia women (76.9%) but only in 2 of 7 (28.6%) in normal pregnancy women showing statistically significant difference ( P=0.032). Conclusion A higher prevalence of nephrin expression in the maternal serum was found in the preeclampsia when compared to the normal pregnancy.

      • KCI우수등재

        부모양육태도가 청소년의 악성댓글작성과 음란사이트열람에 미치는 영향

        박나래(Na Rae Park),오수경(Su Kyung Oh),진미선(Mi Seon Jin),백수정(Su Jeong Baek),정익중(Ick Joong Chung) 한국아동학회 2015 아동학회지 Vol.36 No.2

        The purpose of this study was to examine the impact of parenting attitudes on writing vicious internet replies and the viewing of internet pornography. This study utilized logistic and multiple regression analyses of the 5th wave(2nd grade in middle school) data from the Korean Youth Panel Study(KYPS), as administered by the National Youth Policy Institute. The results of this study can be summarized as follows: First, parenting attitudes were found to decrease the writing of vicious internet replies and the viewing of internet pornography. Second, there was a significant gender difference in the effect of parenting attitudes. As for male adolescents, parental monitoring was more important in the decrease in writing vicious internet replies and the viewing of internet pornography than parental attachment. In contrast, for female adolescents, parental attachment was more important in decreasing the viewing of internet pornography than parental monitoring. On the basis of these results, several implications for youth welfare practice and policy were suggested.

      • KCI등재후보

        Isoquercitrin의 세포 보호 작용과 피부 흡수 증진을 위한 리포좀 제형 연구

        조나래 ( Na Rae Jo ),구현아 ( Hyun A Gu ),박수아 ( Su Ah Park ),한샛별 ( Seat Byeol Han ),박수남 ( Soo Nam Park ) 대한화장품학회 2012 대한화장품학회지 Vol.38 No.2

        본 연구에서는 H<sub>2</sub>O<sub>2</sub>와 rose bengal로 처리된 HaCaT 세포에 있어서 isoquercitrin의 세포 보호 효과를 조사하였다. Isoquercitrin의 피부 전달시스템으로 에토좀 및 탄성 리포좀을 제조하고 입자크기, 포집효율 및 피부 흡수 증진 능력을 평가하였다. Isoquercitrin은 HaCaT 세포에 대해 50 μM의 농도에서 독성을 나타내지 않았다. 5 mM의 H<sub>2</sub>O<sub>2</sub> 및 25 μM의 rose bengal로 HaCaT 세포를 처리하였을 때 isoquercitrin은 산화적 손상에 대항하여 농도 의존적(6.25 ~ 50 μM)으로 세포 보호 효과를 나타내었다. 0.03 % Isoquercitrin을 담지한 에토좀의 입자 크기는 222.85 nm, 포집효율은 82.26 %였다. 0.03 % isoquercitrin 함유 에토좀은 제조 후 2주일 동안 안정하였고, 일정한 입자 크기를 유지하였다. 피부 투과실험 결과 에토좀은 일반 리포좀이나 에탄올 용액에서 보다 우수한 피부 투과능을 보여주었다. 0.1 % Isoquercitrin을 담지한 탄성 리포좀의 최적의 제형은 입자 크기(341.2 nm), 가변형성(59.89), 포집효율(54.3 %) 및 피부투과능 (초기 적하량 대비 54.4 %) 확인을 통해 인지질 대 계면활성제의 비율이 85 : 15인 제형이 가장 우수한 탄성 리포좀 제형임을 나타내었다. In this study, the cellular protective effect of isoquercitrin against H<sub>2</sub>O<sub>2</sub> and rose bengal-indued HaCaT cell damage was investigated. The ethosome and elastic liposome for enhanced transdermal delivery were prepared. Particle size, loading efficiency and cumulative permeated amounts of them were evaluated. Isoquercitrin didn't show any characteristic cytotoxicity at 50 μM. When HaCaT cells were treated with 5 mM H<sub>2</sub>O<sub>2</sub> and 25 μM rose bengal, isoquercitrin protected the cells against the oxidative damage in a concentration dependent manner (6.25 ~ 50 μM). The size of 0.03 % isoquercitrin loaded ethosome was 222.85 nm and the loading efficiency was 82.26 %. The ethosome loaded with 0.03 % isoquercitrin was stable and maintained the constant particle size for 2 weeks after being prepared. The ethosome exhibited more enhanced skin permeability than general liposome and ethanol solution. The optimal ratio of lipid to surfactant of 0.1 % isoquercitrin loaded elastic liposomes was observed to be 89 : 5 through evaluating particle size (341.2 nm), deformability index (59.89), loading efficiency (54.3 %), and skin permeability (54.4 %).

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