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A New Iterative LT Decoding Algorithm for Binary and Nonbinary Galois Fields
Mao, Yuexin,Huang, Jie,Wang, Bing,Huang, Jianzhong,Zhou, Wei,Zhou, Shengli The Korea Institute of Information and Commucation 2013 Journal of communications and networks Vol.15 No.4
Digital fountain codes are record-breaking codes for erasure channels. They have many potential applications in both wired and wireless communications. Most existing digital fountain codes operate over binary fields using an iterative belief-propagation (BP) decoding algorithm. In this paper, we propose a new iterative decoding algorithm for both binary and nonbinary fields. The basic form of our proposed algorithm considers both degree-1 and degree-2 check nodes (instead of only degree-1 check nodes as in the original BP decoding scheme), and has linear complexity. Extensive simulation demonstrates that it outperforms the original BP decoding scheme, especially for a small number of source packets. The enhanced form of the proposed algorithm combines the basic form of the algorithm and a guess-based algorithm to further improve the decoding performance. Simulation results demonstrate that it can provide better decoding performance than the guess-based algorithm with fewer guesses, and can achieve decoding performance close to that of the maximum likelihood decoder at a much lower decoding complexity. Last, we show that our nonbinary scheme has the potential to outperform the binary scheme when choosing suitable degree distributions, and furthermore it is insensitive to the size of the Galois field.
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Mao Minghuan,Yang Liang,Hu Jingyao,Liu Bing,Zhang Xiling,Liu Yili,Wang Ping,Li Hangyu 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
The neuronally expressed developmentally downregulated 4 (NEDD4) gene encodes a ubiquitin ligase that targets the epithelial sodium channel for degradation and has been implicated in tumor growth in various cancers. Hence, in this study, we intended to characterize the functional relevance of the NEDD4-mediated Kruppel-like factor 8/microRNA-132/nuclear factor E2-related factor 2 (KLF8/miR-132/NRF2) axis in the development of bladder cancer. NEDD4 and KLF8 were overexpressed in bladder cancer tissues and were associated with poorer patient survival rates. In bladder cancer cells, NEDD4 intensified the stability and transcriptional activity of KLF8 through ubiquitination to augment cell viability and migratory ability. Our investigations revealed that NEDD4 promotes the binding of KLF8 to the miR-132 promoter region and inhibits the expression of miR-132. KLF8 inhibited the expression of miR-132 to augment the viability and migratory ability of bladder cancer cells. Furthermore, miR-132 downregulated the expression of NRF2 to restrict the viability and migratory ability of bladder cancer cells. In addition, in vivo findings verified that NEDD4 regulates the KLF8/miR-132/NRF2 axis by accelerating tumor growth and lung metastasis. In conclusion, this study highlights NEDD4 as a potential therapeutic target against tumor recurrence and metastasis in bladder cancer.
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Bing-Xin Li,Wan-Yan Li,Yun-Bo Tian,Si-Xuan Guo,Yun-Mao Huang,Dan-Ning Xu,Nan Cao 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.9
Polysaccharide of Atractylodes macrocephala Koidz (PAMK) has been reported to have beneficial effects on regulation of immune responses in mammals and poultry. Nonetheless, the immunoregulatory mechanism of action of PAMK remains unclear. The Toll-like receptor 4 (TLR4) signaling cascade has been proved as a classic polysaccharide-regulated pathway. The aim of this study was to explore the effects of PAMK on the TLR4 signaling pathway in the regulation of spleen function in mice. Ninety-six 5-week-old BALB/c female mice were randomly allocated into four groups with three replicates per group and eight mice per replicate in a single-factor completely randomized experimental design. The control group was fed a basic diet (PAMK free); the other three groups were fed 100, 200, or 400 mg/kg PAMK for 28 days. The spleen index, concentrations of cytokines, and mRNA and protein expression levels of genes related to TLR4 signaling were determined in spleen tissue. Compared with the control group, the spleen index significantly increased in all treatment groups. Concentrations of interleukin 2 (IL-2), IL-4, interferon γ (IFN-γ), and tumor necrosis factor α (TNF-α) in the medium-PAMK group also increased significantly. PAMK in the medium-PAMK group significantly increased both mRNA and protein expression of TLR4, myeloid differentiation factor 88 (MyD88), TNFR-associated factor 6 (TRAF6), TRAF3, and nuclear factor kappa B (NF-κB) in the spleen. In conclusion, PAMK may increase immune-response capacity of the spleen in mice via TLR4–MyD88–NF-κB signaling.
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Mao, Zhu,Liu, Zhuo,Chen, Lei,Yang, Jin,Zhao, Bing,Jung, Young Mee,Wang, Xu,Zhao, Chun American Chemical Society 2013 ANALYTICAL CHEMISTRY - Vol.85 No.15
<P>SERRS (surface-enhanced resonance Raman scattering) has been used to develop and optimize a novel and quantitative MTT assay for living cell viability. This highly sensitive method derives from two factors for formazan signal enhancing: the addition of Au nanoparticles and the resonance effect by 632.8 nm of excitation. The results show that the background elements, such as excessive MTT residues, serum, and the drug, did not interfere with the detection of formazan. Moreover, the detection limit of formazan is as low as 1 ng/mL. With the use of this method to quantify metabolically viable cells, dose–response curves of treated and untreated cells with the drug were constructed on the human lung cancer cell A549. The results also show that the Raman signal generated is dependent on the degree of activation of the cells. In comparison to the traditional method, the main advantages of this method are its rapidity (30 min), high-selectivity, high-precision, and cost-effectiveness (0.1 mg/mL MTT) without time-consuming steps and any modifying or labeling procedure. This work reports on an improved research tool that may help researchers apply this method for in situ cell assays.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2013/ancham.2013.85.issue-15/ac401254s/production/images/medium/ac-2013-01254s_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ac401254s'>ACS Electronic Supporting Info</A></P>
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A Co-design Study of Filters and Oscillator for Low Phase Noise and High Harmonic Rejection
Bing Zhang,Wenmei Zhang,Runbo Ma,Xiaowei Zhang,Junfa Mao 한국전자통신연구원 2008 ETRI Journal Vol.30 No.2
In this paper, we present a novel oscillator (OSC) design. Bandpass filters, which can suppress harmonics, are incorporated into a co-design with an OSC to improve the OSC phase noise and harmonic rejection. The proposed OSC/bandpass filter co-design achieves a phase noise of - 130.1 dBc/Hz/600 kHz and harmonic rejection of 37.94 dB and 40.85 dB for the second and third harmonics, respectively, as compared to results achieved by the OSC before co-design of - 101.6 dBc/Hz/600 kHz and 21.28 dB and 19.68 dB. Good agreement between the measured and simulated results is achieved.
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A New Iterative LT Decoding Algorithm for Binary and Nonbinary Galois Fields
Yuexin Mao,Jie Huang,Bing Wang,Jianzhong Huang,Wei Zhou,Shengli Zhou 한국통신학회 2013 Journal of communications and networks Vol.15 No.4
Digital fountain codes are record-breaking codes for erasure channels. They have many potential applications in both wired and wireless communications. Most existing digital fountain codes operate over binary fields using an iterative belief-propagation (BP) decoding algorithm. In this paper, we propose a new iterative decoding algorithm for both binary and nonbinary fields. The basic form of our proposed algorithm considers both degree-1 and degree-2 check nodes (instead of only degree-1 check nodes as in the original BP decoding scheme), and has linear complexity. Extensive simulation demonstrates that it outperforms the original BP decoding scheme, especially for a small number of source packets. The enhanced form of the proposed algorithm combines the basic form of the algorithm and a guess-based algorithm to further improve the decoding performance. Simulation results demonstrate that it can provide better decoding performance than the guess-based algorithm with fewer guesses, and can achieve decoding performance close to that of the maximum likelihood decoder at a much lower decoding complexity. Last, we show that our nonbinary scheme has the potential to outperform the binary scheme when choosing suitable degree distributions, and furthermore it is insensitive to the size of the Galois field.
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Song, Bing,Yi, Sangheon,Jia, Hongjuan,Nahm, Wook-Hyun,Kim, Jin-Cheul,Lim, Jaesoo,Lee, Jin-Young,Sha, Longbin,Mao, Limi,Yang, Zhongyong,Nakanishi, Toshimichi,Hong, Wan,Li, Zhen Elsevier 2018 Journal of Asian earth sciences Vol.151 No.-
<P><B>Abstract</B></P> <P>To understand historical climate change in western Pacific coastal areas, a sediment core (SOJ-2) from the stable sedimentary environment of the Songjiho Lagoon on the east coast of South Korea was obtained for centennial-resolution palynological analysis. The ages of the SOJ-2 core is well controlled by carbon 14 dating with high-resolution accelerator mass spectrometry (AMS), and the results indicated a general warm to cold climate trend from the mid-Holocene to the present, which can be divided into two different stages: a warmer stage between 6842 and 1297 cal yr BP and a colder stage from 1297 cal yr BP to the present, with fluctuations during these stages. The climate was wetter from 6842 to 6227 cal yr BP and 4520 to 1297 cal yr BP and was drier from 6227 to 4520 cal yr BP. The climate changed to cold and dry during the period from 1297–425 cal yr BP. The impact of human activity on the climate began at approximately 1297 cal yr BP and became pronounced starting in 425 cal yr BP. The general cooling trend may represent a response to decreasing solar insolation; however, the relative dryness or wetness of the climate may have been co-determined by westerlies and the East Asian summer monsoon (EASM). The climate had a teleconnection with the North Atlantic region, resulting from changes in solar activity. Nevertheless, EI Niño–Southern Oscillation (ENSO) activity played an important role in impacting the EASM changes in western Pacific coastal areas.</P> <P><B>Highlights</B></P> <P> <UL> <LI> There is a centennial resolution climate record from 6842 cal yr BP to present. </LI> <LI> The general cooling trend was probably triggered by decreasing solar insolation. </LI> <LI> The precipitation was co-determined by westerlies and the East Asian Summer Monsoon. </LI> <LI> The ENSO activity may be an important factor for East Asian Summer Monsoon change. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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A Bio-memristor with Overwhelming Capacitance Effect
Shuangsuo Mao,Xuejiao Zhang,Bai Sun,Bing Li,Tian Yu,Yuanzheng Chen,Yong Zhao 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.5
A bio-memristor, which was prepared using the bio-materials as basic components, has being become the focus of researchowing to the potential application as medical diagnosis in biomedical field. Herein, an environmentally-friendly and sustainablebio-memristor device with Ag/walnut skin (WS)/ITO structure was fabricated, in which an obvious and reliablyrepeated rectangular current–voltage characteristic curve is observed. Our result shows that the WS, an useless bio-material,can be used to fabricate electronic devices after proper processing. Finally, the memory mechanism based on the conductivefilament mode associated the capacitance effect is ascribed. This work has opened a new way to exploit the next generationbio-electronic device with advantages of environmentally-friendly, sustainable and pollution-free.
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Song, Bing,Li, Zhen,Lu, Houyuan,Mao, Limi,Saito, Yoshiki,Yi, Sangheon,Lim, Jaesoo,Li, Zhen,Lu, Anqing,Sha, Longbing,Zhou, Rui,Zuo, Xinxin,Pospelova, Vera Cambridge University Press 2017 Quaternary research Vol.87 No.2
<B>Abstract</B><P>We reconstructed the centennial climate changes for the period of 9-7 cal ka BP in the upper region of the Changjiang (Yangtze) River Delta plain. A general warming and wetting trend from 8560 to 7220 cal yr BP was indicated by the decrease in <I>Quercus</I> (deciduous) and increases in <I>Quercus</I> (evergreen), <I>Pinus</I>, and Polypodiaceae spores. However, there were several brief climate fluctuations. A notable palynological change, from regional assemblages dominated by arboreal pollen to local assemblages mainly consisting of nonarboreal pollen, reflects climate fluctuations. The key indices of <I>Quercus</I> (deciduous), <I>Pinus</I>, herbs, fern spores, and palynological concentrations showed similar signs of centennial climate fluctuations. We suggest that the climate changes of the Dongge Cave and Yangtze River Delta regions were mainly affected by the East Asian summer monsoon (EASM) during the period of 9-7 cal ka BP. The general warming trend may be associated with an intensified EASM, and solar activity may be one of the important factors driving the centennial climate changes. The ~8.2 ka event was also recorded in the Yangtze River Delta region, which suggests that there was a close relationship between the EASM and Greenland climate during the early Holocene.</P>
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