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한국인에서 도파민 D4 수용체 다형성과 Novelty Seeking 성격 특성의 연관성
이헌정,이홍석,강화연,김린,이민수,서광윤,변영찬 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.4
연구목적 : 저자들은 한국인에서 도파민 D4 수용체(DRD4) 유전자의 다형성과 성격의 관련성을 알아보고자 본 연구를 시행하였다. 방 법 : 173명의 건강한 한국인 여자 청소년(13.88±0.29세)을 대상으로 하여 성격 기질 설문지(Temperament and Character Inventory : TCI)를 작성하도록 하였으며, 이들에서 DRD4 exon Ⅲ 48-bp VNTR(variable numbers of tandem repeats) 다형성을 분석하였다. 결 과 : DRD4 exon Ⅲ Vntr에서 긴 대립유전자(≥5 repeats)를 가진 군이 긴 대립유전자를 가지지 않은군에 비하여 Novelty Seeking 척도 점수가 유의하게 높았다(t=2.11,p=0.037). 결 론 : 본 연구 결과는 DRD4-exon Ⅲ의 긴 대립유전자가 Novelty Seeking 성격과 관련이 있다는 기존의 외국에서의 연구결과를 다시금 확인해주는 것이다. Objectives : We investigated the relationship of personality traits with dopamine D4 receptor(DRD4) exon Ⅲ polymorphism in a Korean population. Methods : We analysed DRD4 exon Ⅲ 48-bp repeats polymorphism in 173 Korean heakthy female adolescents(age=13.88±0.29years) who also completed Temperament and Charater Inventory(TCI). Results : Novelty seeking score of the TCI was significantly higher in the subjects with DRD4 long alleles(≥5 repeats) compares with the subjects without these (t=2.11, p=0.037). Conclusion : The present study supports the previous reports that long repeats of the DRD4-exon Ⅲ polymorphism are relatedwith Novelty Seeking personality.
나노여과 공정에의한 플라스틱첨가제 및 내분비계교란물질의 제거특성
오정익,이석헌 경희대학교 2003 環境硏究 論文集 Vol.12 No.-
The rejection characteristics of sanofiltratios membranes for plastic additives and for endocrine disruptors were investigated. Bisphenol A, estradiow, phtawic acid estEus, phosphoric acid tri-esters, and so on wereused as target solutes. a simplified diffusion convection model was proposed to neglect the effect of the operating pressures and the rejections were converted into one parametEu. The converted rejection parametEu was further separated into two parameters of the size effect parametEu and the parameter of other effects. this separation into two parametEus was successful and the characteristics of the other factors were discussed. the difference is tho material of membranes affected the parametEus and similar membranes gave similar tesdoscy of the parameter.
호기성 SBR공정에 의한 비이온성 계면활성제 NPEO 의 제거
범진영,이석헌 대한상하수도학회 2002 상하수도학회지 Vol.16 No.5
Removal of non-ionic surfactant, nonylphenol ethoxylate (NPEO), by aerobic sequencing batch reactor was investigated using lab scale experimental apparatus. Bio-degradation of NPEO resulted in ethoxylate chain shortening and nonylphenol (NP) production. About 5mg/L of NPEO was introduced and only < 0.09mg/L of NPEO and NP was detected in treated effluent. During the aeration, NPEO and NP in mixed liquor were also reduced. Most of NP and short-chained NPEO were detected in solid phase. Anaerobic condition provided during settling of sludge and decanting of treated effluent caused increase of NP in sludge.
자외선/과산화수소 고도산화공정에 의한 하수 2차 처리수 중의 용존유기물 분해에 미치는 부유물질과 과산화수소 농도의 영향
안규홍,이석헌,안석,김기팔,정민우,맹승규 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3
Secondary effluent of activated sludge process was treated by UV/H_2O_2 advanced oxidation process to investigate the effect of suspended matter and H_2O_2 concentration. With low dosage of UV radiation, the concentration of the dissolved organic compounds measured as DOC could be increased with and without hydrogen peroxide. It was suggested that the cause of DOC increase in treated samples was the decomposition of suspended microbial particles and the incomplete oxidation of dissolved organic compounds. The removal of suspended solid significantly enhanced the degradation of DOC in both UV and catalyzed UV oxidation. Color and odor of secondary effluent was effectively removed. Turbidity was decreased by oxidation and the particle size distribution was shifted to lower range. With increased H_2O_2 dosage (30∼120mg/l), the removal of DOC was enhanced. To obtain the required quality meeting the regulated level for water reuse, additional treatment for turbidity rejection was required.
Fluorescence Excitation-Emission Matrix (FEEM) 특성을 이용한 하수원수 및 처리수 중의 CDD로 표현한 유기성분 모니터링
이석헌 ( Seock Heon Lee ),김종석 ( Jong Seok Kim ),안규홍 ( Kyu Hong Ahn ) 한국물환경학회 2002 한국물환경학회지 Vol.18 No.5
The fluorescence excitation-emmission matrix (FEEM) of domestic waste water, treated effluent of waste water treatment plant, and receiving river water was analyzed to select wavelengths for the monitoring of organic contents as COD. 220 nm/350 nm and 270 nm/350 nm of excitation/emission wavelength for protein-like fluorescence and 240 mm/450 nm and 340 nm/450 nm for humic acid-like fluorescence were suggested as fluorescence peak emitting wavelength pairs, respectively. Without any pre-treatment, protein-like fluorescence peak showed better correlations between COD values and fluorescence intensities than humic acid-like fluorescence peak does. No enhancement in correlation was observed by removing the suspended solids in samples using filtration. However, statistical multiple regression methods, using fluorescence intensity from each peaks and light scattering intensity at 633nm/633nm as variables, resulted in drastic enhancement in correlations with r^2 > 0.9 for measured and predicted COD values.