저체중 출생이 학동기 및 청소년기 소아 천식의 중증도에 미치는 영향에 대한 고찰

정훈 ( Hoon Jeung ),김형대 ( Heung Dae Kim ),이윤진 ( Yun Jin Lee ),이균우 ( Kyun Woo Lee ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2006 소아알레르기 및 호흡기학회지 Vol.16 No.1

목 적 : 본 연구는 저출생 체중아로 출생한 소아에 있어서 학동기 및 청소년기 소아 천식의 중증도에 미치는 영향에 관해서 후향적으로 검토하였다. 방 법 : 대동병원 소아과와 호흡기내과에 통원 중에 있거나 부산 동래구 및 연제구 소재 개인의원에서 대동병원으로 전원 된 천식 환자 중에서 8세 이상 18세 이하의 소아 및 청소년을 대상으로 출생체중을 기준으로 1,500 g 이상 2,500 g 미만인 15명을 추출하여 연구군으로 하고 출생체중 2,500 g 이상이며 연구군의 나이에 일치하는 순서대로 2명씩 추출하여 이 30명을 대조군으로 하였다. 결 과 : 양군을 비교한 결과 천식 중증도는 연구군에서 유의하게 높았다.(P=0.015) 또 흡입 스테로이드 약의 사용 빈도(증례군 13명/15명, 대조군 4명/30명 : P=0.0001)와 사용 기간에 있어서도 연구군에서 유의하게 높게 나왔다.(P= 0.009) 혈중 총 IgE치와 아토피피부염의 유병률은 대조군에서 높았다.(각각 P=0.007, P=0.0001) 폐기능 검사와 PC(20), 특이 IgE 항체는 두 군 사이에 유의한 결과를 볼 수가 없었다.(P>0.05) 결 론 : 천식의 중증도와 흡입 스테로이드 사용의 빈도와 기간 등으로 미루어 볼 때 저출생 체중은 소아 천식의 중증도를 증가시키는 요인 일 수 있음을 시사한다. Purpose : Over the past several decades, the survival rates of low birth weight(LBW; birth weight <2,500 g) infants have been improving. Many of these infants have had bronchial asthma(BA) at childhood and aldolescence. The aim of this study is to investigate whether LBW influenced the severity of BA in prealdolescent children and aldolescence by a retrospective case control study. Methods : 15 LBW children(1,500 g<birth weight<2,500 g) between 8 year-old and 18 year-old with BA visiting Dae-dong hospital as the case group were compared with 2 BA children to each case as the control group(total 30 children) on the basis of following criteria : the same age, he/she attended Dae-Dong hospital or local medical center after 8 years old, birth weight was more than 2,500 g. Asthma severity was modified from 2003 Guideline for management of childhood asthma at The Korean Academy of Pediatric Allergy and Respiratory Disease. PFT(Pulmonary function test) were measured using a portable spirometer. The value are expressed as percentage predicted using standard reference values. Total IgE and specific IgE Ab. were assessed by the PRIST method and MAST Allergy Test. Methacholine challenge test and PC20 was assessed by the Masterlab. Results : LBW group had : a significantly more severe symptoms between 8 year-old and 18 year-old than control group.(P=0.015) A significantly more used to ICSs(Inhaled corticosteroids) and add-on therapy than control group.(P=0.009)(P=0.0001) There were no significant differences in the PFT and PC(20) and specific IgE Ab. between LBW group and control group. But, total IgE level is higher in the control group than in the LBW group. Conclusion : These results suggest that LBW is a risk factor for the severity of BA. We suggest that infants with birth weight of less than 2,500 g have a more severe risk of asthma during prealdolescent children and aldolescence than who were birth weight of more than 2,500 g. [Pediatr Allergy Respir Dis(Korea) 2006;16:38-46]

간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

초등교육을 위한 컴퓨터 교과과정 모델링

李大勳 충주대 2001 한국교통대학교 논문집 Vol.36 No.2

described in this paper Computer Education Curriculum Modelling for Primary School. 1) Analysis and Investigated to Computer Curriculum about some Nation. 2) Think about need to computer education of Korea Primary Students. 3) To propose new curriculum model.

水晶發振器의 溫度補償에 對한 硏究

李大勳 忠州大學校 1987 한국교통대학교 논문집 Vol.21 No.-

In this paper I studed on the temperature compensation circuit and compensation way of crystal oscillator. And I described how to compute device of temperture Compensation circuit I pursued the characteristics of temperature compensation in range of -30℃~70℃ by Colpitts type oscillation circuit consisted of TTL-IC, and conformed that its variation is 2ppm. From the results I presented that the compensation circuit consisted of 3 thermistors is more effective in stability of general oscillation circuit.

절단각의 변화에 따른 수정발진기의 온도보상

李大勳 忠州大學校 1995 한국교통대학교 논문집 Vol.30 No.2

I described in this paper the general characteristics of new cutting(TTC-cut) method crystal resonator and advantages when it is used for OCXO. 1) To describe TTC CUT AND T-F characteristics. 2) TTC-cut shows far better effect than AT-cut on thermal shock, frequency stability and frequency change. 3) We can get compensation characteristics and the good moment with in 1ppm in using resonator for OCXO.

온도보상 수정발진기의 특성별 비교 연구

李大勳 忠州大學校 1998 한국교통대학교 논문집 Vol.33 No.2

I compared the three TCXO Characteristics. Firstly we investigate temperature compensation methods. And described the Load capacitance variable compensation, TTC-cut compensation and digital TCXO method. Finally I anlayzed each temperature compensation method problem.

Ubiquitous System을 이용한 주차 관리 시스템에 관한 연구

이대훈 충주대학교 2006 한국교통대학교 논문집 Vol.41 No.-

It proposed the parking civil official system of the formation parking lot which uses ubiquitous system from the research which it sees. Ubiquitous system introductions all parking civil official will become with all automation and it will be able to expect the effect of the parking space civil official, the in and out and the parking lot operating cost reduction back.

U-Computing 환경 하에서의 e-Learning에 관한 연구

이대훈 忠州大學校 2004 한국교통대학교 논문집 Vol.39 No.1

This paper aims to study Ubiquitous and U-computing in terms of thier use and application. In conclution, I found out that this study can contribute on Cyber-education.

U-Campus에서의 e-Learning 교육 활성화 방안

이대훈 忠州大學校 2007 한국교통대학교 논문집 Vol.42 No.-

This paper contributed to the results as follows; 1) From the U-campus it invested and analysed the necessity of e-learning education. 2) In the e-learning field, it presented the model and it will be able to activate an education. 3) It presented the plan against the activation of e-learning from the U-campus.

RT-LAMP를 이용한 콩황화일반모자이크바이러스의 진단

배대현, 이영훈, 김봉섭, 윤영남, 강범규, 최만수, 구성철, 김현태, 윤홍태, 이수헌, 백인열 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

Soybean yellow common mosaic virus (SYCMV) has been recently reported, it has been occurred a lot with Soybean mosaic virus (SMV) and Soybean yellow mottle mosaic virus (SYMMV) in soybean field. SYCMV belongs to genus of Sobemovirus and induced viral symptoms with yellowing, mottle and mosaic. A reverse transcription loop-mediated isothermal amplification (RT-LAMP) method allowed one-step detection of gene amplification by simple procedure and needed only a simple incubator for isothermal template. This RT-LAMP method allowed direct detection of RNA from virus-infected plants without thermal cycling and gel electrophoresis. In this study, we designed RT-LAMP primers named SYCML-F3/B3/FIP/BIP from coat protein gene sequence of SYCMV. After the reaction of RTLAMP, products were identified by electrophoresis and with the detective fluorescent dye, SYBR Green I. under daylight and UV light. Optimal reaction condition was at 63 for 60min and the primers of RTLAMP showed the specificity for only SYCMV tested in this study.