사구체 수의 증감을 비교할 수 있는 기준 개발

김용진,이지은,이국주,최영호,홍정석 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

Background: The number of glomerulus has been considered one of the etiologic factors especially for focal segmental glomerulosclerosis. However, glomeruli are too many to calculate them correctly. Although the fractionator method has became convinced, in which they used selected sections, not whole kidney sections, with same intervals, it is also very hard to get good results. Because it is still very time-consuming and laborous work which leads to make big observers' biases. Methods and Materials: We designed the index for glomerular number to estimate the tendency of increase or decrease of the number of it in different kidneys and which was evaluated by other conventional methods including fractionator method. Index was based upon the theory by Nyengaard; "the number of glomerulus correlates with the weight of kidney, which is positively correlated with body weight". Calculating formula is the number of glomeruli/surface areas of cortices, which contain calculacted glomeruli multiplies by kidney weight/body weight. Results: We applied this index to kidneys of FGSKist mouse and those of RFM/Nga mouse. The former is spontaneous glomerulosclerosis model with heavy protein uria and renal faille and the latter is the mother side of FGS/Kist mouse but has no glomerular disease or protein aria. The number of glomerulus of FGS/Kist mouse was decreased by 30% to those of RFM/Nga mouse. Conclusion: This index was useful and reliable for estimating the relative glomerular number between two groups.

음성인식을 위한 변환 공간 모델에 근거한 순차 적응기법

김동국,장준혁,김남수 한국음성과학회 2004 음성과학 Vol.11 No.4

In this paper, we propose a new approach to sequential linear regression adaptation of continuous density hidden Markov models (CDHMMs) based on transformation space model (TSM). The proposed TSM which characterizes the a priori knowledge of the training speakers associated with maximum likelihood linear regression (MLLR) matrix parameters is effectively described in terms of the latent variable models. The TSM provides various sources of information such as the correlation information, the prior distribution, and the prior knowledge of the regression parameters that are very useful for rapid adaptation. The quasi-Bayes (QB) estimation algorithm is formulated to incrementally update the hyperparameters of the TSM and regression matrices simultaneously. Experimental results showed that the proposed TSM approach is better than that of the conventional quasi-Bayes linear regression (QBLR) algorithm for a small amount of adaptation data.

톨루엔 폭로근로자의 요중 마뇨산과 자각증상에 관한 연구

김주자,함정오,안규동,이병국,남택승,백남원 大韓産業醫學會 1989 대한직업환경의학회지 Vol.1 No.2

To study the relationship between the urinary hippuric acid and subjective symptoms in toluene exposed workers, urinary hippuric acid was measured and subjective symptoms questionnarire was surveyed in 93 toluene exposed male workers and 96 non-exposed office male workers. The results are as follows: 1. Mean concentration of urinary hippuric acid, which is significantly higher in exposed group than in non-exposed group, was 1.3 g/1, 1.2(GM, GSD respectively) in exposed group and 0.6 g/1, 1.2(GM, GSD respectively) in non-exposed group. 2. Mean concentration of toluene in the air in the workplace, which is significantly higher in the department of coater than in the department of mexing, was 23.4 ppm, 6.2(GM, GSD respectively) in the department of mixing and 59.8 ppm, 3.4(GM, GSD respectively) in the department of coater. 3. Complained rates of subjective symptoms were significantly higher in exposed group than in non-exposed group in all items. 4. In exposed group, complained rate of CNS related symptoms was higher than that of irritation ralated symptoms in the first part but there was no significant difference and complained rate of irritation related symptoms in the second part was significantly higher than that of CNS related symptoms. 5. In exposed group, complained rates of subjective symptoms were not compatible with dose-response relationship by the concentration of urinary hippuric acid, duration of work, department of work, and age group retrospectively.

안양시 지방재정의 강화에 관한 연구

김명국,김주언 안양대학교 복지행정연구소 2003 福祉行政硏究 Vol.19 No.-

안양시의 지방재정은 경기도 내 타 도시에 비해 양호한 상태이며 상위권에 속하고 있다. 재정자립도는 2002년에 83.0%로서 경기도 내 5번째로 도내의 타 도시에 비해 비교적 높은 편이나 중요한 사실은 재정자립도가 매년 하락하고 있고, 투자비의 경우 안양시는 타 도시에 비해 높은 편인데다 점진적인 증가를 보이고 있어 지역사회에 대한 복지 기반 조성과 주민의 복지생활을 위해 바람직한 상황이지만, 경상비의 비중이 31.9%로 경기도 내 타 도시에 비해 가장 높아 탄력적인 예산운영에 한계가 있음을 보여주고 있다. 주민 1인당 지방세 부담액을 보면 안양시의 경우 2002년에 207,000원으로 경기도내 타 자치단체에 비해 비교적 지방세 부담액이 적은 것으로 나타났다. 세입부문에서의 문제는 전체세입 중 자주재원에 속하는 지압세와 세외수입 비중이 매년 감소하는 경향을 보인다는 점이고, 교부금과 보조금 등 의존재원이 늘고 있다는 점이 자율적인 지방자치 실현에 우려되는 바이다. 다행히도 정부혁신지방분권위원회는 7월 29일 재정 ? 세제 개혁 로드맵을 발표하였는 바 그 요지를 보면 중앙정부가 갖고 있는 기능을 과감하게 지방정부로 이양하면서 중앙정부가 움켜쥐고 있던 재정 및 예산도 함께 지방으로 이양하겠다는 것이다. 이제 이에 대한 구체적이고 실천적인 법적 ? 제도적 개선을 기대해 본다.

한국인에서 발견된 이상혈색소에 관한 연구 : β22 glu→ala

김창세,최국주,Harano,Teruo 순천향대학교 1994 논문집 Vol.17 No.4

The abnormal hemoglobins, propositi Park oo and Sung O O, found in Korean, were analyzed for different kinds of methods;agar gel electrophoresis, polyacetate membrane electrophoresis, starch gel electrophoresis. CM-cellulose chromartography, reverse phase HPLC and amino acid sequencing. From the above investigations we were determined the propositi were β-chain variants and the substitution of 22nd amino acid alanine for glutamic acid; ??.

상악 결손부 수복을 위한 측두피판의 이용

정창주,진국범,이동근,윤성필,김귀희,김영조 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

The functional deformity following removal of the maxilla is considerable, especially following maxilla cancer excision. Rehabilitation of oral and maxillofacial region used to be very difficult with prosthesis or traditional flaps. Temporal muscle and fascia flaps have been described for immediate reconstruction following hemi-maxillectomy, but not total maxillectomy. The muscle and superficial fascia of the temporal area differ in their physical characteristics, vascular supply and clinical applications. Both can be employed independently or simultaneously as regional flaps in the reconstruction of a variety of complex craniofacial defects. Four case is presented in which 3 case maxilla cancer, one case non-union after maxilla fracture, and all case showed successful use of this flap. Only one patient developed partial necrosis of the flap ; significant necrosis did not occur in any other patient. This present paper reviews the anatomy, surgical technique and utilisation of temporal muscle and fascia flaps.

Adaptive Control Strategy in Electromagnetic Levitation System

Kim Seok-Joo,Kim Jong-Moon,Kweon Soon-Man,Kim Kook-Hun,Kim Yong-Joo 제어로봇시스템학회 1990 제어로봇시스템학회 국내학술대회 논문집 Vol.1 No.2

Changes in Sensitization Rate to Weed Allergens in Children with Increased Weeds Pollen Counts in Seoul Metropolitan Area

Kim, Joo-Hwa,Oh, Jae-Won,Lee, Ha-Baik,Kim, Seong-Won,Kang, Im-Joo,Kook, Myung-Hee,Kim, Bong-Seong,Park, Kang-Seo,Baek, Hey-Sung,Kim, Kyu-Rang,Choi, Young-Jean The Korean Academy of Medical Sciences 2012 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.27 No.4

<P>The prevalence of allergic diseases in children has increased for several decades. We evaluated the correlation between pollen count of weeds and their sensitization rate in Seoul, 1997-2009. Airborne particles carrying allergens were collected daily from 3 stations around Seoul. Skin prick tests to pollen were performed on children with allergic diseases. Ragweed pollen gradually increased between 1999 and 2005, decreased after 2005 and plateaued until 2009 (peak counts, 67 in 2003, 145 in 2005 and 83 grains/m<SUP>3</SUP>/day in 2007). Japanese hop pollen increased between 2002 and 2009 (peak counts, 212 in 2006 and 492 grains/m<SUP>3</SUP>/day in 2009). Sensitization rates to weed pollen, especially ragweed and Japanese hop in children with allergic diseases, increased annually (ragweed, 2.2% in 2000 and 2.8% in 2002; Japanese hop, 1.4% in 2000 and 1.9% in 2002). The age for sensitization to pollen gradually became younger since 2000 (4 to 6 yr of age, 3.5% in 1997 and 6.2% in 2009; 7 to 9 yr of age, 4.2% in 1997 and 6.4% in 2009). In conclusion, sensitization rates for weed pollens increase in Korean children given increasing pollen counts of ragweed and Japanese hop.</P>

Comparison of Intranasal Ciclesonide, Oral Levocetirizine, and Combination Treatment for Allergic Rhinitis

Kim, Chang-Hoon,Kim, Jin Kook,Kim, Hyun Jun,Cho, Jin Hee,Kim, Jung-Soo,Kim, Yong-Dae,Lee, Heung-Man,Kim, Sung Wan,Cho, Kyu-Sup,Lee, Sang Hag,Rhee, Chae-Seo,Dhong, Hun-Jong,Rha, Ki-Sang,Yoon, Joo-Heon The Korean Academy of Asthma, Allergy and Clinical 2015 Allergy, Asthma & Immunology Research Vol.7 No.2

<P><B>Purpose</B></P><P>To evaluate the efficacy and safety of once-daily ciclesonide in comparison to both levocetirizine alone, and a ciclesonide/levocetirizine combination in patients with seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR).</P><P><B>Methods</B></P><P>Subjects exhibiting moderate to severe allergic rhinitis for longer than 1 year were randomized in an open-label, 3-arm, parallel group, multicenter study. Subjects received 200 µg ciclesonide, 5 mg levocetirizine, or a combination of both. Changes from baseline until the end-of-study visit (2 weeks following) were evaluated by reflective total nasal symptom scores (rTNSSs), reflective total ocular symptom scores (rTOSSs), physician-assessed overall nasal signs and symptoms severity (PANS), and rhinoconjunctivitis quality-of-life questionnaires (RQLQ).</P><P><B>Results</B></P><P>Significant improvements in rTNSS, PANS, and RQLQ in the ciclesonide monotherapy group were observed in comparison to the levocetirizine alone group. Three individual symptoms of rTNSS, including runny nose, nasal itching, and congestion, were improved in the ciclesonide-treated group. rTOSS scores for ciclesonide monotherapy improved from baseline, but no superiority over levocetirizine was shown. The absolute score and changes in rTNSS and PANS were positively correlated. Ciclesonide spray was more effective than levocetirizine in reducing nasal symptoms in both SAR and PAR patients. Ciclesonide and levocetrizine were well tolerated alone and in combination.</P><P><B>Conclusions</B></P><P>Our results provide support for an AR and its Impact on Asthma (ARIA) recommendation stipulating that ciclesonide is superior to levocetirizine for the treatment of AR, with tolerable safety. Addition of levocetirizine to ciclesonide did not give further clinical benefit over monotherapy.</P>

Adaptive Control Strategy in Electromagnetic Levitation System

Seok Joo Kim,Jong Moon Kim,Soon Man Kweon,Kook Hun Kim,Yong Joo Kim 대한전자공학회 1990 대한전자공학회 학술대회 Vol.1990 No.01