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김재환,김상우,조원모,강희설,조영무,Kim, Jae-Hwan,Kim, Sang-Woo,Cho, Won-Mo,Kang, Hee-Seol,Cho, Young-Moo 한국축산환경학회 1996 축산시설환경학회지 Vol.2 No.2
The objective of this study was to estimate the investment limit in equipment capital by Capital Recovery Method. The data used was collected from 23 Hanwoo(Korean Native Cattle) farms in 1994. The necessary time for herd size expansion was average 5 years from opening(9.7 heads) to 50 heads, 4 years from 50 to 100heads, 3 years from 100 to 150 heads, and 2 years from 150 to 200 heads, respectively. It took 14 years from opening to 200 heads of herd size. The debts for fattening cattle farms were 15.2million won for the size of 50 heads, 37.1 million won for the size of 100 heads and 89.0 million won for the size 200 heads, respectively. Average rates of debt interest were 5.1 % 7.2 and 10.8, correspendingly. As the hear size increased, debt interest rates also increased due to government funds limit. The investment limits in equipment capital perfarm household were 77.7 million won for 50 heads, 135.1 for 100 heads, and 294.3 for 200 heads for 5,500 won per kg liveweight, 70.7 million won for 50 heads, 122.6 for 100 heads and 269.3 for 200 heads for 5,000 won per kg liveweight, 63.6 million won for 50 heads 110.0 for 100 heads and 244.2 for 200 heads for 4,500 won per kg liveweight.
Seol, Dong Lim,Kim, Hyeong In,Lee, Woo Jung,Jang, Won Hee,Kim, Jeong Koo,Lee, Sung Jae,Yang, Young Il Trans Tech Publications, Ltd. 2005 Key Engineering Materials Vol.288 No.-
<P>A culture system that is capable of providing even and uniform distribution and deposition of cells and extracellular matrix (ECM) is desired to enhance biological functions of the tissue-engineered artificial dermis (TEADs). For this purpose, we have developed a perfusion culture system that offers uniform exchange of nutrients and gases along the scaffold. Viability and effectiveness of the system were investigated by comparing biological and mechanical properties of TEADs. Results showed that the TEADs constructed by the perfusion culture system revealed significantly increased cell growth, ECM synthesis, and elastic modulus compared to those by the conventional static culture system. In addition, histological findings indicated that cells were more evenly distributed and ECM deposition increased in TEADs with the perfusion culture system. Therefore, it can be suggested that the perfusion culture system can constitute a more promising approach for constructing the TEADs.</P>
Kim, Kyung Hwan,Kim, Yong Hwy,Dho, Yun-Sik,Kim, Jung Hee,Hong, Sang Duk,Choi, Jung Won,Seol, Ho Jun,Nam, Do-Hyun,Lee, Jung-Il,Park, Chul-Kee,Kong, Doo-Sik Elsevier 2018 World neurosurgery Vol.114 No.-
<P><B>Objective</B></P> <P>Despite advances in endoscopic techniques, retrochiasmatic craniopharyngiomas (CPs) are difficult to remove completely, because the low-lying optic chiasm often provides an obstacle to an endoscopic endonasal approach. This study aimed to identify the endoscopic surgical outcomes of the retrochiasmatic CP and resolve the issues related to low-lying optic chiasm.</P> <P><B>Methods</B></P> <P>We reviewed 154 consecutive patients with CP who underwent endonasal endoscopic resection from February 2009 to April 2017 at 2 independent institutions. The topographic relationship of the tumor with the third ventricle, stalk, and optic chiasm and clinical outcomes were investigated.</P> <P><B>Results</B></P> <P>Retrochiasmatic CPs were found in 142 of 154 patients (92.2%). The median follow-up time was 25 months. Gross total resection and near-total resection were achieved in 113 patients (79.6%) and 21 patients (13.8%), respectively. Postoperative cerebrospinal fluid leaks were found in 16 patients (11.3%). Low-lying and high-lying chiasms were found in 44 patients (31.0%) and 98 patients (69.0%), respectively. Low-lying chiasm did not affect clinical outcomes including the extent of resection. Patients with low-lying chiasm showed a marginal trend for postoperative visual deterioration. The ventricular growth pattern representing the origin of the tumor and previous surgery were significantly associated with the position of the optic chiasm (<I>P</I> = 0.007 and 0.001, respectively).</P> <P><B>Conclusions</B></P> <P>An endoscopic endonasal approach is an effective surgical approach for retrochiasmatic CP, even in tumors with low-lying chiasm. However, a thorough and careful dissection is necessary to prevent visual deterioration.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Low-lying chiasm can interfere with endoscopic approach for craniopharyngioma. </LI> <LI> The position of optic chiasm is affected by tumor origin previous surgery. </LI> <LI> Low-lying chiasm does not alter clinical outcomes including extent of resection. </LI> <LI> Endoscopic endonasal approach is feasible even in the presence of low-lying chiasm. </LI> </UL> </P>
Three-Dimensional Printing of Highly Conductive Carbon Nanotube Microarchitectures with Fluid Ink
Kim, Jung Hyun,Lee, Sanghyeon,Wajahat, Muhammad,Jeong, Hwakyung,Chang, Won Suk,Jeong, Hee Jin,Yang, Jong-Ryul,Kim, Ji Tae,Seol, Seung Kwon American Chemical Society 2016 ACS NANO Vol.10 No.9
<P>Moving printed electronics to three dimensions essentially requires advanced additive manufacturing techniques yielding multi functionality materials and high spatial resolution. Here, we report the meniscus-guided 3D printing of highly conductive multiwall carbon nano tube (MWNT) microarchitectures that exploit rapid solidification of a fluid ink meniscus formed by pulling a micronozzle. To achieve high-quality printing with continuous ink flow through a confined nozzle geometry, that is, without agglomeration and nozzle dogging, we design a polyvinylpyrrolidone-wrapped MWNT ink with uniform dispersion and appropriate rheological properties. The developed technique can produce various desired 3D microstructures, with a high MWNT concentration of up to 75 wt % being obtained via post-thermal treatment. Successful demonstrations of electronic components such as sensing transducers, emitters, and radio frequency inductors are also described herein. We expect that the technique presented in this study will facilitate selection of diverse materials in 3D printing and enhance the freedom of integration for advanced conceptual devices.</P>
Seol, Dong-Won,Hur, Jun-Wook,Kim, Dong-Soo,Nam, Yoon-Kwon,Bang, In-Chul,Park, In-Seok The Korean Society of Fisheries and Aquatic Scienc 2009 Fisheries and Aquatic Sciences Vol.12 No.1
We conducted a histological analysis to investigate the influence of nutritional changes on melano-macrophages (MMs) accumulation in the kidney of sub-adult rock bream (Oplegnathus fasciatus). Four experimental groups were established (initial control, control, fed and starved), and fed commercial feed amounting to 1-3% of their body weight for 2 weeks prior to initiation of experiments. Kidney MMs with dark brown pigment were randomly observed in the kidneys of starved fish, increasing rapidly after 4 weeks, while deposition levels remained low throughout the experiment in the control and fed groups. These results suggest that catabolic tissue breakdown is a major factor contributing to the formation of pigments within MMs. Results also suggest that the degree of MMs deposition in the kidney can be used as alternative indicators in identifying starvation in wild and cultured rock bream.
Kim, Minah,Park, Hyeung Ju,Seol, Jae Won,Jang, Jeon Yeob,Cho, Young-Suk,Kim, Kyu Rae,Choi, Youngsok,Lydon, John P,DeMayo, Francesco J,Shibuya, Masabumi,Ferrara, Napoleone,Sung, Hoon-Ki,Nagy, Andras,Al Blackwell Publishing Ltd 2013 EMBO molecular medicine Vol.5 No.9
<P>The features and regulation of uterine angiogenesis and vascular remodelling during pregnancy are poorly defined. Here we show that dynamic and variable decidual angiogenesis (sprouting, intussusception and networking), and active vigorous vascular remodelling such as enlargement and elongation of ‘vascular sinus folding’ (VSF) and mural cell drop-out occur distinctly in a spatiotemporal manner in the rapidly growing mouse uterus during early pregnancy — just after implantation but before placentation. Decidual angiogenesis is mainly regulated through VEGF-A secreted from the progesterone receptor (PR)-expressing decidual stromal cells which are largely distributed in the anti-mesometrial region (AMR). In comparison, P<SUB>4</SUB>-PR-regulated VEGF-A-VEGFR2 signalling, ligand-independent VEGFR3 signalling and uterine natural killer (uNK) cells positively and coordinately regulate enlargement and elongation of VSF. During the postpartum period, Tie2 signalling could be involved in vascular maturation at the endometrium in a ligand-independent manner, with marked reduction of VEGF-A, VEGFR2 and PR expressions. Overall, we show that two key vascular growth factor receptors — VEGFR2 and Tie2 — strikingly but differentially regulate decidual angiogenesis and vascular remodelling in rapidly growing and regressing uteri in an organotypic manner.</P>
A new method of fabricating robust freeform 3D ceramic scaffolds for bone tissue regeneration
Seol, Young‐,Joon,Park, Dong Yong,Park, Ju Young,Kim, Sung Won,Park, Seong Jin,Cho, Dong‐,Woo Wiley Subscription Services, Inc., A Wiley Company 2013 Biotechnology and bioengineering Vol.110 No.5
<P><B>Abstract</B></P><P>Fabrication of three‐dimensional (3D) scaffolds with appropriate mechanical properties and desired architecture for promoting cell growth and new tissue formation is one of the most important efforts in tissue engineering field. Scaffolds fabricated from bioactive ceramic materials such as hydroxyapatite and tricalcium phosphate show promise because of their biological ability to support bone tissue regeneration. However, the use of ceramics as scaffold materials is limited because of their inherent brittleness and difficult processability. The aim of this study was to create robust ceramic scaffolds, which have a desired architecture. Such scaffolds were successfully fabricated by projection‐based microstereolithography, and dilatometric analysis was conducted to study the sintering behavior of the ceramic materials. The mechanical properties of the scaffolds were improved by infiltrating them with a polycaprolactone solution. The toughness and compressive strength of these ceramic/polymer scaffolds were about twice those of ceramic scaffolds. Furthermore, the osteogenic gene expression on ceramic/polymer scaffolds was better than that on ceramic scaffolds. Through this study, we overcame the limitations of previous research on fabricating ceramic scaffolds and these new robust ceramic scaffolds may provide a much improved 3D substrate for bone tissue regeneration. Biotechnol. Bioeng. 2013; 110: 1444–1455. © 2012 Wiley Periodicals, Inc.</P>