KI-180과 KI-188 칼슘조성물이 어린쥐의 성장발육에 미치는 영향

박승만(Seung-Man Park),성기승(Ki-Seung Seong),이종석(Jong-Seok Lee),이옥환(Ok-Hwan Lee),한찬규(Chan-Kyu Han) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.3

본 연구에서는 KI-188 칼슘과 KI-180 조성물이 성장발육에 미치는 효과를 조사하였다. 시험기간중 KI-188 칼슘과 KI-180 식이군이 대조군 보다 성장률과 평균 식이섭취량은 증가하였다. 체장은 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 평균 3.55 mm 더 길었고, 등뼈길이는 KI-180 식이군이 대조군 보다 통계적인 차이는 없었지만 0.5 mm 더 길었다. 대퇴골 무게는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 무거웠으며, 대퇴골길이는 대조군에 비해 각각 평균 0.89, 1.09 mm 더 길었다. 혈당, 총콜레스테롤 및 중성지방 농도는 차이가 없었고, 칼슘농도는 KI-188 칼슘과 KI-180 식이군 보다 대조군이 유의하게 높았다. 백혈구와 혈소판수는 차이가 없었고, 적혈구, 혈색소 및 헤마토크릿치는 대조군이 KI-188 칼슘과 KI-180 식이군 보다 통계적으로 높았다. ALP활성은 KI-180 식이군이 대조군 보다 통계적으로 높았고, osteocalcin농도는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 유의하게 높았다. 혈청 testosterone 농도는 KI-188 칼슘과 KI-180 식이군과 대조군 간에 차이가 없었다. IGF-1과 IGFBP-3 농도는 KI-180 조성물이 대조군 보다 각각 20%, 11% 정도 유의하게 더 높았다. 이상의 결과를 검토할 때 KI-188 칼슘과 KI-180 조성물은 어린쥐의 성장과 골격의 발달을 촉진시키고, 성장호르몬의 분비능을 양적으로 유도하여 전반적인 성장발육에 유효한 작용이 있는 것으로 사료된다. Herbs have active components that promote the growth rate of both animals and human. The KI-180 and KI-188 calcium food formulae contain Acanthopanacis cortex, Bombysis corpus and hoelen, seaweed calcium, chlorella extract, spirulina, colostrum powder, and other natural and functional components. We evaluated the growth-promoting effects of these formulae by analyzing the weight, femur and backbone, alkaline phosphatase, osteocalcin, testosterone, insulin-like growth factor (IGF)-1, and IGF binding protein-3 (IGFBP-3) of growing rats. Growing rats administered with KI-180 and KI-188 calcium showed the increase of body weight, body length, and femur weight and length of growing rats. In addition, administration of KI-180 and KI-188 calcium increased the alkaline phosphatase activity, the levels of osteocalcin and the growth hormones IGF-1 and IGFBP-3 of growing rats. The impact of KI-180 and KI-188 calcium on the physical development of growing rats suggests that the incorporation of these food formulae in the diets of growing children may promote the physical development.

직장 카르시노이드 종양에서 Ki-67 발현의 예후적 중요성

홍수민 ( Su Min Hong ),김유선 ( You Sun Kim ),문정섭 ( Jung Seop Moon ),김진남 ( Jin Nam Kim ),오명기 ( Myoung Ki Oh ),권선옥 ( Sun Ok Kwon ),정성연 ( Seong Yeon Jeong ),홍성우 ( Seong Woo Hong ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2

Background/Aims: Rectal carcinoid tumors can be resected with endoscopy, and it is important to assess their prognostic factors. We evaluated the potential of Ki-67 expression as a prognostic factor in rectal carcinoid tumors. Methods: We retrospectively reviewed the medical records of 37 patients with rectal carcinoid tumors who got endoscopic resection from January 2001 to January 2011 at Inje University Seoul Paik Hospital. We analyzed their endoscopic and histologic findings, Ki-67 expression, clinical outcome, and prognosis. Results: The mean age (±SD) of the patients was 56.3±10.7 years, and the male : female ratio was 3.6:1. The mean tumor size was 0.5±0.4 cm, 33 patients showed grade 1 tumors (89.2%) and the average Ki-67 expression was 0.7±1.2%. Thirty five patients underwent endoscopic mucosal resection, and two required endoscopic submucosal dissection. Eight patients had positive margins after resection, but no cases of lymphovascular invasion were identified. The median follow-up duration was 21.4±25.4 months, and no recurrences were observed. Conclusions: In low grade rectal carcinoid tumors which are lack of central depression on colonoscopy, the expression of a molecular marker of malignant potential, Ki-67, was low. Therefore, endoscopic resection seemed to be a safe and effective treatment for these tumors.

인체대장암에서의 Cyclin 유전자의 발현

백원기,서민호,서성일,문성희,박종욱,최병길,배옥석 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.2

여성 외음부에 발생한 선상 편평상피세포암종

김창옥,양기화,강석진,이안희,김병기,김선무 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.1

RBL-2H3 세포에서 Spermine에 의한 히스타민 유리와 칼슘유입에 미치는 상백피의억제효과

채옥희,강경진,신인호,김영기,이무삼,전병득 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.2

敎職員 開發 : 그 最近의 硏究 動向

尹基玉 仁川敎育大學校 1991 論文集 Vol.25 No.2

The purpose of this study is to integrate, from the literature on staff development, information that can be used for developing new staff development activities and programs and for fostering further research in the field. With the comprehensive definition of staff development, the past, present and future trend of staff development is considered: Staff development began to receive increasing attention in the mid-1970s. It is evolving from an emphasis on skill development to shared experiences designed to modify the culture of a school. So staff developers of future will need more knowledge of subject matter and instructional techniques. They will also need to have expertise in dealing with the culture of an organization. As theories related with the effectiveness of staff development, andragogy, developmental theories, organization development, and ways of connecting the university to school-connecting for knowledge production and use, connecting for initial preparation of professionals, connecting for development of experienced teachers and schools and restructuring the university connection-are mentioned. Characteristics of effective staff development programs grouped into four categories-planning and management concerns, program content, training components, method of delivery and the Dakota Wholistic Model for Staff Development is presented. Finally based on the research studies, suggestions for the development of effective staff development programs are stated.

裝學의 發達과 現況

尹基玉 仁川敎育大學校 1991 論文集 Vol.25 No.1

유아교육교사와 유아의 인간관계

윤기영,지옥정 서원대학교 교육연구소 1988 敎育發展 Vol.7 No.1

The purpose of this study is to provide desirable directions for human relations in Early childhood education. To serve this purpose, the meaning, characters and ideal teacher's role are observed. 1.The characters of human relations between kindergarten teachers and young children are ① Teaching and learning relations, ② Hardly have choice relations, ③ Giving and Taking influences relations, ④ Sharing love relations, ⑤ Complicated relations. 2.The idel teacher's role and attitudes are ① qualified teachers, ② Authoritative teachers, ③ Sharing love effectively, ④ Trying to develop themselves, ⑤ Growing with young children. 3.As conclusion, It is necessary to establish more effective ability of human relations for Kindergarten teachers. It is recommended to have lecture of human relations in teacher's college.

타액 및 혈액 오염이 상아질접착에 미치는 영향

김기옥 慶北大學校 齒科大學 1996 慶北齒大論文集 Vol.13 No.-

상아질 접착제의 전처리과정에서 발생할 수 있는 타액 및 혈액에 의한 접착치면의 오염이 상아질접착제의 접착강도에 미치는 영향을 알아보고, 오염을 제거하여 접착성능이 회복되는 정도를 관찰할 목적으로, 발거된 소의 하악 전치의 순면을 노출시켜 각 단계별 오염의 시점, 타액 및 혈액 등의 오염원, 그리고 건조 및 재적용 등의 오염후 재처리 방법 등을 조건으로 All Bond^R 2와 Bisfil^™(Bisco Inc., U.S.A.) 및 Scotchbond^™ Multipurpose와 Z100 (3M Co., U.S.A.)을 상아질 접착제와 수복용 복합레진으로 각각 사용하여 인장접착강도를 측정하고 주사전자현미경적 관찰을 시행하여 다음과 같은 결과를 얻었다. All-Bond^R 2의 산처리후 타액오염을 다시 산처리한 경우를 제외하고는 (p>0.05) 전체적으로 All Bond^R 2 및 Scotchbond^™ Multipurpose 공히 오염원, 재처치 유무, 오염시점에 관계없이 모든 상아질 오염군이 오염되지 않은 군에 비해 낮은 접착 강도를 나타내었다 (p>0.05). 혈액오염이 타액오염에 비해 큰 폭의 접착강도 저하현상을 나타냈으며 (p<0.01), 접착강화제 적용후 시점에 오염된 경우가 산처리후 시점에서 오염된 경우에 비해 상아질접착제의 접착성능이 더욱 저하되는 것으로 나타났다(p<0.01). 오염의 시점과 접착력 회복과의 관계를 알아본 결과 산처리후 시점에서의 타액오염은 산처리를 다시 시행함으로써 다소간 접착력이 회복되나 혈액오염에는 큰 효과가 없는 것으로 나타났고 접착강화제 적용후 시점에서의 오염은 타액이나 혈액 공히 접착강화제를 재적용하는 방법이 접착력 회복에 효과가 있는 것으로 나타났다. The purpose of this study was to elucidate the effect of blood- and saliva-contamination during dentin pretreatment procedure on tensile bond strength, and to investigate the effect of contaminant-removing treatments on the recovery of bond strength of dentin bonding agents. Dentin specimens prepared form freshly extracted bovin mandibular anterior teeth were divided into non-contaminated control and contaminated experimental groups. The specimens of the contaminated group were contaminated with saliva or blood after etching or priming procedure, followed by contaminant-removing treatments. All the specimens were bonded with All Bond6® 2 dentin bonding agent Bisfil^™ composite resin or Scotchbond^™ Multipurpose and Z100. After all the bonded specimens were stored in 37℃ distilled water for 24 hours, tensile bond strengths were measured. The comtaminated dentin and fractured dentin surfaces were examined under the scanning electron microscope. The results were as follows: Contaminated specimens showed lower bond strength than non-contaminated ones regardless of the kind of contanminant, contamination time and contaminant-removing treatments, except specimens which were acid-etched following saliv contamination after etching in All Bond® 2 Groups (p<0.05). Blood contaminant resulted in much bond strength decrease than saliva ones(p<0.01), and contamination after priming resulted in much decrease in bond strength than after etching (p<0.01). Re-etching resulted in increase of bond strength in the specimens contaminated with saliva after etching but not in blood contaminated ones. Re-priming resulted in increase of bond strength in the specimens contaminated after priming regardless of the kind of contaminatnt.

인라인 스케이트 T300m 출발동작 분석

박기범,양정옥,이중숙 한국운동역학회 2003 한국운동역학회지 Vol.13 No.2

Park, K-B, Yang, J-O and Lee, J-S. An Analysis of Starting Motions in Time 300m Inline Skating. Korean Journal of Sport Biomechanics, Vol. 13, No. 2, pp. 123-137. This study is to present more effective starting skills through analysis of kinematic characteristics of starting motions in 300m Time Trials of Inline Skating. To achieve this goal, 6 athletes, 3 in the national team and 3 in business teams were chosen and their starting motions were examined with three-dimensional image analyses. The results of analyses in regard of positions and speed of the bodily center and angles, angular velocity, and linear velocity of articulations of lower limbs by sections of starting motions are as follows; In case of the central position, though it is effective to reduce the air resistance by lowering the upper part of the body maximumly, it is reasonable to accelerate by raising the upper part of the body to some degree for the running posture at the lower speed in the starting section. In the starting section, it is efficient to minimize the period of time in touching the ground. For this, it is necessary to train for taking motions without slippage while touching the ground. While 3 athletes in business teams kicked the ground as running right after the starting, the others in the national team slid on the ground. As the number of steps increased, the movable speed changed quickly. Thus he movable speed of athletes in the national team indicated big differences in two to three steps. If these factors are well supported, the push-away starting method might be better than the running starting method in terms of improvement of records.