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      • KCI등재

        Functional Constraints Focused on Recoverability in Phonology

        Lee, Bo Rim,Lee, Ki Jeong 대한언어학회 2000 언어학 Vol.8 No.3

        Lee, Borim and Ki-jeong Lee. 2000. Journal of the Linguistic Association of Korea, 8(3), 47-63. In this paper we deal with some functional considerations behind phonological processes which appear to destroy the underlying contrasts. A series of truncation phenomena, in their nature, result in loss of underlying information, which in turn damages intelligibility in communication. From a functional point of view, there may exist certain processes which seem to compensate for the destruction caused by extensive truncation. We discuss a neutralization process, an influence of deleted segments over the remaining segments, a homonymy-avoiding process, and a case of restructuring in a suffix of a secret language of Lardil. We conclude, then, that all these phenomena deserve new interpretations in the context of recoverability of underlying contrasts, which is based on functional constraints in languages. (Wonkwang University and Hanyang University)

      • AHCISCOPUSKCI등재
      • KCI등재

        AMP-activated Protein Kinase 활성체인 Metformin의 모발 성장에 미치는 영향

        문혜림 ( Hye-rim Moon ),박기영 ( Ki-young Park ),강현지 ( Hyun Ji Kang ),이우진 ( Woo Jin Lee ),원종현 ( Chong Hyun Won ),장성은 ( Sung Eun Chang ),이미우 ( Mi Woo Lee ),최지호 ( Jee Ho Choi ),박경훈 ( Gyeong-hun Park ) 대한피부과학회 2019 대한피부과학회지 Vol.57 No.4

        Background: AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays a pivotal role in the balance of cellular energy metabolism. Recent studies have reported that AMPK has numerous roles in physiological conditions, and dysregulation of AMPK induces pathological processes and diseases. However, the role of AMPK and its activators have not yet been studied in the context of hair growth regulation. Objective: To investigate the effects of metformin on dermal papilla (DP) and outer root sheath (ORS) cells, as well as the role of the AMPK pathway in hair growth. Methods: We evaluated whether metformin, a well-known AMPK activator, had any beneficial effects on hair growth. In addition, to evaluate the molecular and cellular mechanisms that were involved, protein levels of AMPK and β-catenin were analyzed. Results: Metformin increased the cellular proliferation of human DP and ORS cells. Ki-67 expression was also significantly increased after metformin treatment in the ex vivo hair follicle organ culture. Furthermore, DP and ORS cells treated with metformin had a significant increase in AMPK phosphorylation, which in turn suppressed β-catenin degradation and enhanced its nuclear accumulation. Conclusion: We demonstrated that metformin promoted hair growth via the AMPK/β-catenin signaling pathway in vitro with DP and ORS cells. The hair-promoting effects of AMPK activators may potentially be used for the treatment of alopecia, and further investigation will be needed in the future. (Korean J Dermatol 2019;57(4):175∼ 181)

      • 산업대학 건축공학과 교육과정 개발에 관한 연구

        임응찬,한인웅,이승준,박재호,조방현,서형수,정구용,한기원,김진원,임상규,이재윤 三陟大學校 1996 論文集 Vol.29 No.2

        By impproving the educational program of the Department of Architectural Engineering and studying the theory of learning and the applied method necessary for the development of nation and society, we should develop a satisfying course of education to meet the demand and skill in the industralized society for the purpose of cultivating men of baility with great personalities and creative minds. Therefore, this study focused on classifying several kinds of occupations in the prart of architectured related to what graduates from the department of Architectural Engineering go with into the society. Accordingly after choosing some works adequate to each occupation by the proposed curricula, we tried to establish the scope of education and courses corresponding to the jobs and thus and develop a satisfying curriculum.

      • 히드록실아민으로 변형된 5.8S RNA의 가수분해

        이강렬,서기림 聖心女子大學校 1980 論文集 Vol.11 No.2

        효모세포에서 5.8 S RNA 를 추출하여 ??로 5′-끝을 표지시켰다. 히드록실아민으로 반응시킨 RNA 를 아닐린으로 가수분해하여 겔 전기이동으로 RNA 조각들을 분리하였다. 히드록실아민은 우리딘 잔기에서 사슬을 끊어냄을 알았다. 5.8 S RNA was extracted from yeast cells. 5'-end of 5.8 S RNA was labelled by ??. Hydroxylamine treated RNA was hydrolyzed by the action of aniline. Hydrolyzed fragments of 5.8 S RNA were seperated from slab gel electrophoresis. The phosphodiester bond of RNA was found to be cleaved at the uridine moiety.

      • SCOPUSSCIEKCI등재

        부정교합의 유형에 따른 두개저와 하악골의 형태에 관한 연구

        權奇烈,鄭圭林,李起受 대한치과교정학회 1986 대한치과교정학회지 Vol.16 No.1

        This study was designed to investigate the variation of mandibular pattern and cranial base and their association in the cranioofacial malocclusion. The material was the 165 cephalometric radiographs taken from craniofacial malocclusion. The sample was devided into two groups by age child group aged from 10 to 13 years and adult group aged over 18 years, and each group was devided into 3 types of malocclusion; classⅠ, ClassⅡ div. 1 and ClassⅢ malocclusion. Child group consist of 35 sample and adult group consist of 20 samples in each malocclusion type. Various angular and linear measurements on the cephalometric radiographs were recorded and statistically analyzed. The results of the study were as follows; 1. The cranial base angle was largest in ClassⅡ div. 1 malocclusion and smallest in ClassⅢ malocclusion. 2. The anterior cranial base length was largest in ClassⅡ div. 1 malocclusion but posterior cranial base length did not show statistical difference. 3. The mandibular body length of ClassⅢ malocclusion was larger than those of ClassⅠ and ClassⅡ div. 1 malocclusion in the adult group but did not shown difference in the child group. The ramus height of ClassⅢ malocclusion was larger than those of ClassⅠ and ClassⅡ div. 1 malocclusion in the child and adult group, but there were no difference between ClassⅠ and ClassⅡ div. 1 malocclusion. 4. The mandibular position was showed low correlation with the cranial base angele.

      • 국내육성 오차드그라스 품종들의 캘러스 형성율 및 식물체 재분화 효율

        김기용,강경민,배은경,이인애,임용우,최기준,박근제,손대영,조진기 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

        Comparisons of callus formation ratios from seed explants, callus sizes, regeneration ratios from callus and regeneration efficiency for 4 orchardgrass (Dactylis glomerata L.) varieties (Three were developed in Korea and one was imported from foreign nation) are as follows; Jangbeol 102 (67.0%) has the highest callus formation ratio in 4 weeks incubated callus after bedding the seed explants, but Potomac (68.4%) has the highest ratio in 6-seek callus. Potomac (3.93cm) has the highest callus size in 4-week callus, but Jangbeol 101 (4.32cm) has the highest size in 6-week callus. Jangbeol 101 (17.7%) has the highest plant regeneration ratio in 4-week callus, but Potomac (37.4%) has the highest raion in 6-week callus. Jangbeol 102 (11.5%) has the highest plant regeneration efficiency in 4-week callus, but Potomac (25.6%) has the highest efficiency in 6-week callus.

      • KCI등재

        Diffuse Leptomeningeal Glioneuronal Tumor with FGFR1 Mutation in a 29-Year-Old Male

        Minsu Kim,Ki Rim Lee,Gheeyoung Choe,Kihwan Hwang,Jae Hyoung Kim 대한영상의학회 2023 대한영상의학회지 Vol.84 No.4

        This study reports on diffuse leptomeningeal glioneuronal tumor (DL-GNT) in a 29- year-old male. DLGNT is a rare central nervous system (CNS) tumor mostly seen in children and only few cases have been reported in adult patients. Our patient presented with a chronic headache that lasted for five months. MR imaging showed mild hydrocephalus, multiple rim-enhancing nodular lesions in the suprasellar cistern, diffuse leptomeningeal enhancement in the lumbosacral area, and multiple small non-enhancing cyst-appearing lesions not suppressed on fluid attenuated inversion recovery (FLAIR) images in the bilateral basal ganglia, thalami, and cerebral hemispheres. Under the impression of germ cell tumor with leptomeningeal seeding, the patient underwent trans-sphenoidal tumor removal. DL-GNT was pathologically confirmed and FGFR1 mutation was detected through a next-generation sequencing test. In conclusion, a combination of leptomeningeal enhancement and multiple parenchymal non-enhancing cyst-appearing lesions not suppressed on FLAIR images may be helpful for differential diagnosis despite overlapping imaging features with many other CNS diseases that have leptomeningeal enhancement.

      • SCOPUSSCIEKCI등재

        臼齒部와 前齒部의 咬合 狀態에 關한 硏究

        具仲會,高鎭煥,鄭圭林,李起受 대한치과교정학회 1980 대한치과교정학회지 Vol.10 No.1

        The purpose of this study was (1) to determine the prevalence of some causes by which dental occlusion might be affected, (2) to determine the prevalence of malocclusion, and types of molar, vertical incisor and horizontal incisor relationships, and (3) to examine the sex difference in the prevalence ratios, and (4) to determine the between-examiner differences in assessing types of dental occlusion. The material consisted of 1281 males and 811 females, total 2091 persons, aged 17 to 21 years. Two examiners who were graduate students in the orthodontic course, examined independently dental occlusion of the material. Before calculating the statistics, the subjects consisted of 156 males and 164 females, total 320 persons, having any one or more causes suspected to affect dental occlusion, was eliminated. Then the remained subjects, 1124 males and 647 females, total 1771 persons, were assessed. The results were as follows 1. The prevalence of some causes by which dental occlusion might be affected was 15.32 percent. The missing rate of any one or more first molars was 8.85 percent, that of any one or more teeth positioned anterior to the first molar was 3.83 per cent. The prevalence of crossbite of the first molar was 0.48 per cent, that of retained primary teeth was 0.77 percent, and that of orthodontic treatment was 0.43 per cent. 2. The rate of between-examiner difference was 12.53 per cent in assessing the types of molar relationship, 18.86 percent in assessing the types of horizontal incisor relationship, and 26.37 percent in assessing the types of horizontal incisor relationship. 3. There was no sex difference in the prevalence ratios of the types of molar relationship. The prevalence of Class 1 molar relationship was 80.91 percent, that of Class Ⅱ was 5.03, that of Class Ⅱ subdivision was 4.01, percent, that of Class Ⅲ was 5.99 percent and that of Class Ⅲ subdivision was 4.07 percent. 4. In the prevalence of the types of horizontal incisor relationship, there were no sex differences except that of Class Ⅱ division 2. The prevalence of Class 1 horizontal incisor relationship was 73.12 percent, that of Class Ⅱ division 1 was 12.03 percent, that of Class Ⅱ division 2 was 6.58 percent in male and 4.33 percent in female, and that of Class Ⅲ was 9.09 percent. 5. In the prevalence of the types of vertical incisor relationship, there were no sex differences except that of deep bite, The prevalence of open bite was 2.20 per cent, that of edge-to-edge bite was 9.15 percent, that of normal bite was 76.34 percent, and that of deep bite was 14.15 percent in male and 9.12 percent in female. 6. There was no sex difference in the prevalence of malocclusion the prevalence of malocclusion was 82.67 percent and that of normal occlusion was 17.33 percent. 7. There was a tendency that when Class 1 molar relationship changed to Class Ⅱ, incisor relationships were to be larger overjet or upright upper incisors and deep bite, but when that changed to Class Ⅲ molar relationship, these were to be cross bite and openbite.

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