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      • n-CdS_(0.46)Se_(0.54)/p-Cu_92-x)S_(0.46)Se_(0.54) 이종접합 태양전지의 제작과 그 특성에 관한 연구

        유상하,최승평,이상열,홍광준,서상석,김혜숙,전승룡,윤은희,문종대,신영진,정태수,신현길,김택성,유기수 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.16 No.-

        승화방법에 의해 CdS_0.46Se_0.54 단결정을 성장하여 결정구조를 조사하고, Van der Pauw 방법으로 Hall effect를 측정하여 carrier density의 온도 의존성과 mobility의 온도 의존성을 조사하였다. 성장된 CdS_0.46Se_0.54 단결정을 치환반응하여 n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 이종접합 태양전지를 제작하였다. Spectral response, 전류-전압특성 및 전력변환 효율을 조사하여 그 결과로부터 개방전압은 0.48V, 단락 전류 밀도는 21mA/㎠, fill factor와 전력변환효율은 각각 0.75와 9.5%를 얻었다. CdS_0.46Se_0.54 single crystal was grown by a sublimation method. The crystal structure and the temperature dependence of carrier density and mobility of CdS_0.46Se_0.54 single crystal were studied. Heterojunction solar cells on n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 were fabricated by the substitution reaction. The spectral response, the J-U characteristics and the conversion efficiency of the n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells were studied. The open-cricuit voltage, short-circuit density, fill factor and conversion efficiency of n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells under 80mW/㎠ illumination were found to be 0.48V, 21mA/㎠, 0.75 and 9.5%, respectively.

      • 백부자(白附子)가 혈압(血壓), 호흡(呼吸) 및 시상하부(視床下部)의 전기자극(電氣刺戟)에 의(依)한 심맥관계반응(心脈管系反應)에 미치는 영향(影響)

        신홍기(Shin, Hong-Kee),김기순(Kim, Kee-Soon),이병희(Lee, Pyung-Hee) 대한생리학회 1973 대한생리학회지 Vol.7 No.2

        The effects of ethanol extacts of aconite root (Aconitum koreanum) on mean arterial pressure, heart rate, pulse pressure, and respiration were investigated and also studied the effect on electrical activation of the hypothalamus in cats. From the present experiment the following results were obtained. 1) On administering 5 mg or 10 mg aconite extracts per kg of body weight, the mean arterial blood pressure declined markedly possibly as the result of negative inotropic and chronotropic effects of aconite. 2) From the enhanced pressor responses to intravenously injected epinephrine, the existance of vasodilatory effect of the aconite was suggested. 3) After administration of aconite extract, no significant differences were observed in the presser responses to carotid occlusion and to electrical stimulation of the hypothalamus. It is, therefore, concluded that the aconite extract exerts no significant effect on the excitability of hypothalamus as well as medullary cardiovascular center of cats. 4) After administration of 5 ~ 10 mg/kg aconite extracts, respiratory rate was increased while depth of respiration decreased. On the otherhand, respiratory rate was markedly decreased by injection of 20 mg/kg aconite into animal.

      • 一酸化炭素 血色素의 正常値에 對하여

        安鈺平,李用雨,金箕洪 최신의학사 1978 最新醫學 Vol.21 No.3

        The deleterious effects of carbon monoxide on the human body have long been known. Recently, increasing incidence of carbon monoxide poisoning has been a serious problem since coal briquette has come into a wider use. The development of an accurate method of screening the possible cases of carbon monoxide poisoning urgently needed. Normal values of carboxyhemoglobin will be a acquired by more studies. The author reports the normal values of carboxyhemoglobin of 388 random cases of age of 20-50 in Hanyang Hospital by the Heilmyer-modified method. The results obtained are as follows: 1. In a normal individual who do not smoke, man's average of carboxyhemoglobin saturation was 1.98±1.94%, while woman's was 2.08±1.65%, higher than man's. 2. In subjects who smoke, the mean value of carboxyhemoglobin was 3.84±2.75%. 3. The level of carboxyhemoglobin was slightly higher in heavy smoker than in light smoker.

      • Ethanol이 식염성고혈압(食鹽性高血壓) 유발과정(誘發過程)에 미치는 영향(影響)

        김기순,이병희,신홍기,Kim, Kee-Soon,Lee, Pyung-Hee,Shin, Hong-Kee 대한생리학회 1973 대한생리학회지 Vol.7 No.2

        In 30 rats divided into salt, ethanol and salt plus ethanol groups, the effect of ethanol on the course of hypertension induction with the salt ingestion was studied. The results obtained from the present study are as follows. 1) In salt group mean arterial blood pressure elevated to plateau (about 140 mmHg) in two weeks and the increased blood pressure was well maintained throughout entire experimental period. 2) By four weeks after ethanol ingestion, mean arterial blood pressure of ethanol group was slightly decreased followed thereafter by slow restoration to control value. And it was believed that decline of blood pressure observed in this case probably was not resulted from cardiac depression. 3) As mean arterial pressure in salt plus ethanol group remained rather low compared with that of salt group, it was suggested that ethanol may have a dose reduction effect in the course of hypertension induction by excessive salt ingestion. It was, however, not possible from the result of present study to decide that low blood Pressure in this group was resulted whether from enhanced sodium excretion activity of ethanol or from effect on blood pressure of ethanol itself.

      • KCI등재
      • Resistance of Free-living Stages of Soil-transmitted Parasites of Pesticides

        Soh, Chin-Thack,Lee, Keun-Tae,Cho, Kee-Mok,Ahn, Yung-Kyum,Kim, Sang-June,Chung, Pyung-Rim,Im, Kyung-Il,Min, Hong-Ki INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1975 YONSEI REPORTS ON TROPICAL MEDICINE Vol.6 No.1

        消化器系寄生蟲 卵子, 幼蟲, 및 씨스트의 數種農藥에 對한 抵抗力을 調査하였다. 寄生蟲은 犬鈞蟲, 東洋毛樣線蟲의 卵子 및 幼蟲, 蛔蟲, 鞭蟲의 卵子, 痢疾아메바「씨스트」였고, 農藥은 現在 韓國에서 가장 널리 使用되고 있는 殺菌劑(Captan, Polyramcombi), 殺蟲劑 (Diazinon, B.T.C., Hepta) 및 除草劑(Simazin, P.C.P.)等 數種을 採擇하였으며 使用農藥의 濃度는 實際 農村에서 適用되고 있는 用量을 參酌하였다. 寄生蟲 幼蟲에 對한 農藥 露出時間은 24時間까지로 하였으나 必要에 따라 48時間까지도 延長하였다. 農藥別 殺蟲效果는 다음과 같다. Captan : 鈞蟲卵子는 2培稀釋量(2:400)에서 2時間內에 死滅하였고, 其他 蟲卵에 對하여는 殺卵效果가 없었다. 痢疾아메바「씨스트」는 6時間內에 完全死滅하였다. 鈞蟲 및 東洋毛樣線 幼蟲에 對해서는 24時間內에 뚜렷한 殺蟲效果를 볼 수 없었다. Polyramcombi (1 : 800) : 모든 實驗 線蟲類 卵子 및 幼蟲 그리고 痢疾아메바「씨스트」에 對한 顯著한 殺蟲效果를 볼 수 없었다. Diazinon (1 : 800) : 鈞蟲卵子 만이 2培稀釋量(2 :800)에서24時間內에 死滅되었으며 其他 蟲卵에 對한 殺蟲效果를 없었다. 鈞蟲 rhabditoid 幼 은 12時間內에, 痢疾아메바「씨스트」는 1時間內에 死滅되었다. B.T.C. (30mg/50cm²) : 蟲卵 및 痢疾아메바「씨스트」에 對한 殺滅效果는 없었고, 鈞蟲卵子는 2培 稀釋量 (2×30mg/50cm²)에서 24時間內에 死滅하였다. 鈞蟲 rhabditoid 幼蟲은 12時間內에 完全死滅하였으나 被襄幼蟲은 그 50%가 生存하였다. Hepta (30mg/50cm²) : 實驗蟲卵 및 痢疾아메바「씨스트」에 對해서는 殺滅效果가 없었고東洋毛樣線蟲 rhabditoid 幼蟲만이 露出 12時間에 死滅되었다. Simazin (0.5mg/50cm²) : 蟲卵 및 痢疾아메바「씨스트」에 對한 殺滅效果는 없었고, 東洋毛樣線蟲 被襄幼蟲만이 露出 12時間에 死滅되었다. P.C.P. (5mg/50cm²) : 鈞蟲卵子만이 2培稀釋量 (2×5mg/50cm²)에서 24時間內에 殺卵되었을 뿐 其他 試供蟲卵에 對한 殺卵效果는 없었다. 鈞蟲 rhabditoid 幼蟲은 24時間內에, 被襄幼蟲은 48時間內에 死滅되었고, 東洋毛樣線蟲 rhabditoid 幼蟲 및 被襄幼蟲은 露出 6時間內에 死滅되었다. 痢疾아메바「씨스트」는 露出 3時間以內에 完全 死滅되었다. 以上의 結果로 보아 常用農藥은 犬鈞蟲, 東洋毛樣線蟲, 蛔蟲, 鞭蟲卵에 對한 殺蟲效果는 없었고 Diazinon, B.T.C., P.C.P., Simazin等의 農藥은 鈞蟲 및 東洋毛樣線蟲의 幼蟲, 特히 第1期 幼蟲 즉 rhabditoid幼蟲의 경우 그 實際適用濃度에서 顯著한 殺蟲效果를 나타내었으며 痢疾아메바「씨스트」는 Captan, Diazinon, P.C.P.와 같은 常用農藥에 對하여 露出 1∼6時間內에 完全死滅됨을 알 수 있었다. Lethal action of pesticides, which are used in present day Korea, to free living stages of hookworm, Trichostrongylus, Ascaris, Tricharis and cyst of Entamoeba histolytica was examined. The pesticides were bactericides (Captan, Polyramcombi), insecticides (Diazinon, B.T.C. and Hepta), and herbicides (Simazin, P.C.P.). The concentration of the pesticides was prepared on the basis of practical application in field. The routine period of exposure was 24 hours, and the results are briefly summarized as below ; Captan (1 : 400) : No lethal action to the eggs tested was destroyed within 24 hours at the 2-fold concentration. Entamoeba histolytica cysts were destroyed within 6 hours. Polyramcombi (1 : 800) : No significant lethal action was appeared to eggs and larave, and cysts of E. histolytica. Diazinon (1 : 800) : No lethal action to the eggs tested was destroyed within 24 hours at the 2-fold concentration. The rhabditoid larvae of hookworm were killed within 12 hours, and cysts of E. histolytica within one hour. B.T.C. (30mg/50cm²) : No lethal effect was confirmed to eggs, and cysts of E. histolytica tested. Hookworm eggs were destroyed at the 2-fold concentration within 24 hours. Hookworm rhabditoid larvae were killed within 12 hours, but the filariform larve survived 56% at the same period. Hepta (30mg/50cm²) : No lethal effect was proved to eggs, and cysts of E. histolytica tested. Rhabditoid larvae of Trichostrongylus were destroyed within 12 hours. Simazin (0.5mg/50cm²) : No lethal effect was proved to eggs, and cysts of E. histolytica tested. Filariform larve of trichostrongylus only were destroyed within 12 hours. P.C.P. (5mg/50cm²) : No lethal effect was proved to eggs, but hookworm eggs were destroyed within 24 hours at the 2-fold concentration. The rhabditoid larvae of hookworm were destroyed within 24 hours, and the filariform larvae within 48 hours. The rhabditoid and filariform larvae of Trichostrongylus were killed within 6 hours. Cysts of E. histolytica were destroyed within 3 hours. The overall results indicate that the conventional pesticides show no significant lethal effect to the eggs of hookworm, Trichostrongylus, Ascaris and Trichuris. But the larval forms specially the rhabditoid forms of hookworm and Trichostrongylus, will be destroyed either by Diazinon, B.T.C., P.C.P. and Simazin at the ordinary concentrations of the field application. Entamoeba histolytica cysts also will be destroyed by Captan, Diazinon and P.C.P. within 1-6 hours.

      • KCI등재후보

        만성신부전 백서에서 항고혈압제의 종류에 따른 신부전의 진행과 사구체의 형태학적 변화

        홍성진,김교순,김병길,박경화,김기혁,Hong Sung-Jin,Kim Kyo-Sun,Kim Pyung-Kil,Park Kyung-Hwa,Kim Kee-Hyuck 대한소아신장학회 2002 Childhood kidney diseases Vol.6 No.2

        목적 : 만성신부전은 신장에 병적 손상이 있어 지속적으로 신기능이 저하되어 말기신부전에 이르게 된다. 만성신부전의 진행을 지연시킬 수 있는 인자 중 혈압조절이 중요한 것으로 알려져 있다. 저자들은 부분 신절제를 이용하여 만성신부전을 유발시킨 후 항고혈압제로 enalapril과 nicardipine을 투여하여 만성신부전의 진행에 미치는 영향을 조사하였다. 대상 및 방법 : 백서에서 5/6 신절제술로 만성신부전을 유발시킨 후 무작위로 대조군, enalapril 투여군(E군), nicardipine 투여군(N군)으로 나누어 4주 간격으로 꼬리 동맥압을 측정하고 12주째 24시간 소변 단백량과 creatinine배설량, 혈청 creatinine을 측정한 후 희생시켜 신조직을 광학현미경과 전자현미경으로 관찰하여 사구체의 형태학적 소견을 조사하였다. 결과 : 1. 신절제 후 대조군은 지속적으로 혈압이 증가하였으나 E군과 N군에서는 정상 혈압이 유지되었다. 2. 12주째 E군에서 요단백량은 대조군과 N군에 비하여 유의하게 적었다. 3. 12주째 조사한 신장의 형태계측학적 검사에서 E군과 N군 모두에서 mesangium의 증식이 대조군에 비하여 유의하게 적었으나 사구체 용적은 E군에서만 대조군에 비하여 적었다. 4. 대조군, E군, N군간의 상피세표 족돌기의 형태학적 변화의 차이는 없었다. 결론 : 부분 신절제로 유발한 만성신부전 백서에서 enalapril, nicardipine 모두 고혈압을 예방하였으나 enalpril 투여군에서 단백뇨의 감소와 신병변 발생 예방 효과가 우수하였으며, 상피세포 족돌기의 변화에는 차이가 없었다. Purpose: Hypertension accelerates the progression of chronic renal disease, whether it results from, or causes, the renal disease. Therefore, the control of hypertension is one of the important factors that retard the rate of renal deterioration. We compared the effects of different antihypertensive agents on renal function and glomerular morphology In subtotal nephrectomized rats. Materials and methods: After induction of chronic renal failure with 5/6 nephrectomy, the rats were divided into three groups; control group (Group C), enalapril group (Group E), and nicardipine group (Group N). Systolic blood pressure was measured by tail cuff method every 4 weeks until 12 weeks after nephrectomy. At 12 weeks after nephrectomy, all rats were placed in metabolic cages for 24 hour urine collections to measure urinary protein and creatinine excretion. After urine collection and blood sampling for serum creatinine, all rats were sacrificed. The renal tissue was processed for morphometric study with light microscope and electron microscope. Results: 1. The blood pressure of Group C increased progressively, but both enalapril and nicardipine prevented the development of hypertension, and the two drugs were equally effective in maintaining normal blood pressure throughout the study. 2. Twenty-four hour urinary protein excretion was lower in Group E compared to Group C and Group N 3. Mesangial expansion score in both treated groups were significantly lower than the control group. Mean glomerular volume in Group E was significantly reduced compared to Group C and Group N. There was no significant difference in mean glomerular volume between Group C and Group N. 4. There was no significant difference in podocyte structural changes, estimated by filtration slit length density, among control, enalapril and nicardipine treated groups. Conclusion: Control of hypertension with enalapril or nicardipine afforded considerable protection from mesangial expansion in the rat remnant kidney model. But protein excretion and glomerular growth were significantly reduced in Group E compared to Group N. There was no significant difference in podocyte structural changes among the 3 groups.

      • SCOPUSKCI등재
      • KCI등재

        Lactase Deficiency Diagnosed by Endoscopic Biopsy-based Method is Associated With Positivity to Glucose Breath Test

        Ik Hyun Jo,Chang Nyol Paik,Yeon-Ji Kim,Ji Min Lee,Soo Yeon Choi,Kee Pyung Hong 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.1

        Background/AimsLactase deficiency, which has many similarities with small intestinal bacterial overgrowth (SIBO), causes various gastrointestinal symptoms. We estimate the prevalence of SIBO in patients with intestinal symptoms from dairy products and investigate the association between lactase deficiency (LD) and SIBO. MethodsThis prospective study included patients with functional intestinal symptoms from dairy product indigestion. A questionnaire on gastrointestinal symptoms, a hydrogen (H2)-methane glucose breath test (GBT) for SIBO, and lactose intolerance quick test (LQT) for LD using upper gastrointestinal endoscopy were performed. ResultsA total of 88 patients, 29 (33.0%) with severe and 36 (40.9%) with mild LD were included. Sixteen patients (18.2%) were GBT positive. Patients with LQT negativity indicating severe LD showed a higher positivity to GBT or GBT (H2) than the historic controls (27.6% vs 6.7%, P = 0.032). There was no difference in the items on the symptom questionnaire according to the presence of LD or SIBO, except for higher symptom scores for urgency in GBT-positive patients. There were more LQT-negative patients in the GBT (H2)-positive group than in the other groups (27.6% vs 10.2%, P = 0.036). Moreover, only GBT (H2)-positivity was significantly associated with a higher risk of LQT negativity in multivariate analysis (OR, 4.19; P = 0.029). ConclusionsSIBO producing H2 is common in patients with severe LD suspected lactose intolerance. SIBO may be a new therapeutic target for managing intestinal symptoms in patients with lactose intolerance.

      • KCI등재

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