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( Jae Won Byun ),( Kyung Hyun Lee ),( Ha Young Kim ),( Soon Seek Yoon ),( Ji Youl Jung1 ),( Woo Seog Jeong1 ),( Jae Ku Oem ),( Jong Soo Lim ),( Myoung Heon Lee ),( You Chan Bae ) 한국예방수의학회(구 한국수의공중보건학회) 2013 예방수의학회지 Vol.37 No.1
Nine cattle among 18 in a native Korean herd died or were euthanized within 3 days. The affected cattle showed cowshed. The pigs and dogs had been fed leftover food originating from nearby restaurants, and the cattle could presumably reach the contaminated food in the pig troughs. Necropsy revealed a few chicken bones and red pepper pieces as well as large amounts of grain and rice straw hay mixed in the rumen. Botulism type D was isolated in the ruminal contents of one of the cattle. We speculated that the outbreak was associated with the cattle incidentally eating presumably contaminated leftover food from the pig trough.
( Sang-Cheol Bae ),( Jin-Hye Cha ),( Jung-Yoon Choe ),( Sung Jae Choi ),( Soo-Kyung Cho ),( Won-Tae Chung ),( Chung-Il Joung ),( Young-Ok Jung ),( Young Mo Kang ),( Dong-Wook Kim ),( Jinseok Kim ),( Y 대한류마티스학회 2018 대한류마티스학회지 Vol.25 No.2
Objective. Productivity loss was compared by 3-stage of disease activity and associations between higher disease activity and high productivity loss were identified. Methods. Data were extracted from Rheumatoid Arthritis (RA) Patient-reported Outcomes Research, which enrolled 2,000 RA patients (>20-year) on disease-modifying-antirheumatic-drugs (DMARDs) (≥ 6-month) from December 2012 to June 2013. This included 1,457 RA patients with the disease activity score (DAS-28-ESR) in their medical charts. Productivity loss in time and indirect cost was estimated using The World Health Organization Health and Work Performance Questionnaire (HPQ). Baseline characteristics and productivity loss outcomes were compared according to DAS-28-ESR groups. Results. 84.4% were females, 54.2% had low DAS-28-ESR (<3.2), and 38.2% and 7.6% had moderate (3.2∼5.1) and high DAS-28-ESR (>5.1). Patients with moderate to high DAS-28-ESR had higher lost productivity time (LPT) and monthly costs of LPT than those with low DAS-28-ESR (time in hours: 110.0±58.4 vs. 132.4±57.2 vs. 71.5±52.0, p<0.0001; monthly costs of LPT in 1,000 Korean won: 1,097±607 vs. 1,302±554 vs. 741±531, p<0.0001). Multiple regression analyses revealed significant associations with high LPT in high (adjusted odds ratio [OR]=3.87, 95% confidence interval [CI]: 2.18∼6.87) and moderate DAS-28-ESR (adjusted OR=1.88, 95% CI: 1.41∼2.52) compared to low DAS-28-ESR. In addition, positive associations with high monthly costs of LPT were observed in high (adjusted OR=3.45, 95% CI: 1.98∼5.99) and moderate DAS-28-ESR (adjusted OR=1.93, 95% CI: 1.43∼2.54) compared to low DAS-28-ESR. Conclusion. Timely therapeutic strategies should be taken into consideration given that the RA patients with moderate to high DAS-28-ESR showed strong associations with high productivity loss for effective management of RA. (J Rheum Dis 2018;25:122-130)
유지원 ( Ji-won Yu ),신보미 ( Bo-mi Shin ),신선정 ( Sun-jung Shin ),배수명 ( Soo-myoung Bae ) 한국치위생학회 2021 한국치위생학회지 Vol.21 No.4
Objectives: This study aimed to analyze the status of dental care in underserved areas of Korea. Methods: This study targeted 229 cities in Korea. The analytical index was revised and supplemented with variables related to dental care, and the “oral health level” indexes were further selected to provide a total of 20 analytical indexes. All selected indexes were converted into T scores (cited by the Korea Health Promotion Institute) and subjectively weighted. Finally, the regional oral health indices and areas were derived. PASW Statistics 25.0 (SPSS Inc. Chicago, IL, USA) was used to analyze descriptive statistics. Results: Gyeongbuk Cheongsong-gun had the highest dental underserved index. The city with the highest regional oral health underserved index was Jeonnam Shinan-gun. Daegu Jung-gu had the lowest dental underserved index and regional oral health underserved index. Regional gaps existed between dental care and the regional oral health underserved index according to the city province (p<0.001). Conclusions: To continuously evaluate oral health conditions and projects centered on vulnerable areas, it is necessary to develop indicators to derive vulnerable areas for dental care and to develop effective public dental policies.
김병호 ( Byung Ho Kim ),감신 ( Sin Kam ),배상근 ( Sang Geun Bae ),김건엽 ( Keon-yeop Kim ),이원기 ( Won Kee Lee ),홍남수 ( Nam-soo Hong ),박형근 ( Hyeung-keun Park ),이혜진 ( Heyjean Lee ),조은정 ( Eun-jung Cho ),채성철 ( Shung C 한국보건정보통계학회(구 한국보건통계학회) 2017 보건정보통계학회지 Vol.42 No.1
Objectives: This study was conducted to investigate economic feasibility of operating Regional Cardiocerebrovascular Centers using cost-benefit analysis. Methods: The current study assessed cost and benefit data collected from nine hospitals which were designated as Regional Cardiocerebrovascular Centers between 2008 and 2010. Results: The operation of Regional Cardiocerebrovascular Centers reduced mortality rate and length of stay due to acute myocardial infarction and stroke and also decreased disability occurred after stroke. The total calculated cost of operating nine Regional Cardiocerebrovascular Centers was 19.85-22.30 billion won and the minimum benefit calculated was 23.98 billion won. Applying the maximum cost and the minimum benefit, the net benefit was 1.68 billion won, which is estimated to 190 million won per Regional Cardiocerebrovascular Center. Conclusions: The present study revealed that the operation of Regional Cardiocerebrovascular Centers was economically beneficial. The benefit would be larger if intangible benefit such as the long-term effects to community hospitals and enhancement of quality of life of patients and their families are considered.
기상조절(인공강우와 안개저감)의 경제적 가치 추정 연구
이철규(Chulkyu Lee),장기호(Ki-Ho Chang),차주완(Joo-Wan Cha),정재원(Jae-Won Jung),정진임(Jin-Yim Jeong),양하영(Ha-Young Yang),서성규(Sung-Kyu Seo),배진영(Jin-Young Bae),강선영(Sun-Young Kang),최영진(Young-Jean Choi),조하만(Ha-man Cho) 한국기상학회 2010 대기 Vol.20 No.2
We estimate the economic benefit of weather modification (precipitation enhancement and fog dissipation) by assuming its operation for the considered regions. Based on the statistical data, the economic benefit of the virtually operational precipitation enhancement experiments for the Andong and Imha basins, where the natural precipitation is relatively lack in South Korea, is calculated 348 for the water resources, 22,458 for forest fire prevention, and 28,458 million won/year for the drought relief. The benefit of the fog dissipation operation for the Incheon International Airport is estimated 7,365 million won/year for the flight delay due to fog. The calculated ratio of benefit to cost for precipitation enhancement operation for the basins is 14.07, which is comparable to that conducted in other countries.
DBC1 does not function as a negative regulator of SIRT1 in liver cancer
BAE, HYUN JIN,CHANG, YOUNG GYOON,NOH, JI HEON,KIM, JEONG KYU,EUN, JUNG WOO,JUNG, KWANG HWA,KIM, MIN GYU,SHEN, QINGYU,AHN, YOUNG MIN,KWON, SO HEE,PARK, WON SANG,LEE, JUNG YOUNG,NAM, SUK WOO Spandidos Publications 2012 Oncology letters Vol.4 No.5
Jung‑Hyun Park,Gyung Bae Bang,Kee‑Ahn Lee,Yong Son,Yeong Hwan Song,Byoung‑Soo Lee,Won Rae Kim,Hyung Giun Kim 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.11
Various studies related to additive manufacturing (AM) have been conducted with Ni-based superalloy and multiscaleinvestigations of widely used Inconel 718 superalloy have been actively performed with the selective laser melting (SLM)method. The formation of defects and thermal residual stress during the SLM process could particularly affect productquality and life-time. Thus, to optimize the SLM process condition for Inconel 718 boasting the minimum of deterioratingproperties, the microstructural study was conducted with various energy densities and preheating temperatures. The SLMprocess condition over 99.9% of density was established and the change of microstructural and mechanical characteristicswere confirmed according to the preheating temperature from 50 to 150 °C. The fraction of the low angle grain boundary(LAGB) and the stored strain energy per unit volume gradually decreased as the preheating temperature increased. In particular,while maintaining the mechanical properties, the thermal residual stress in the direction perpendicular to the buildingdirection decreased under the half value of yield strength which could induce deformation.
Bae, Mi-Kyung,Lim, Jung Ah,Kim, Sangsig,Song, Yong-Won Optical Society of America 2013 Optics express Vol.21 No.2
<P>We demonstrate a novel optical sensor for use in explosive gas detection, having a simple structure, ultrahigh sensitivity, room-temperature sensing/refreshing operation, and no local power requirements. The sensor relies on a fiber Fabry-P?rot interferometer prepared using poly(4-vinylpyridine), which induces cavity expansion upon absorption of nitrobenzene, thereby shifting the phase matching conditions of the resonating modes. An estimated sensitivity limit as low as 5 ppb was achieved.</P>
Jung, Kwang Hwa,Kim, Jeong Kyu,Kim, Min Gyu,Noh, Ji Heon,Eun, Jung Woo,Bae, Hyun Jin,Chang, Young Gyoon,Shen, Qingyu,Park, Won Sang,Lee, Jung Young,Nam, Suk Woo American Chemical Society 2012 Environmental science & technology Vol.46 No.23
<P>Persistent organic pollutants (POPs) are degradation-resistant anthropogenic chemicals that accumulate in the food chain and in adipose tissue, and are among the most hazardous compounds ever synthesized. However, their toxic mechanisms are still undefined. To investigate whether characteristic molecular signatures can discriminate individual POP and provide prediction markers for the early detection of POPs exposure in an animal model, we performed transcriptomic analysis of rat liver tissues after exposure to POPs. The six different POPs (toxaphene, hexachlorobenzene, chlordane, mirex, dieldrin, and heptachlor) were administered to 11-week-old male Sprague-Dawley rats, and after 48 h of exposure, RNAs were extracted from liver tissues and subjected to rat whole genome expression microarrays. Early during exposure, conventional toxicological analysis including changes in the body and organ weight, histopathological examination, and blood biochemical analysis did not reflect any toxicant stresses. However, unsupervised gene expression analysis of rat liver tissues revealed in a characteristic molecular signature for each toxicant, and supervised analysis identified 2708 outlier genes that discerned the POPs exposure group from the vehicle-treated control. Combination analysis of two different multiclassifications suggested 384 genes as early detection markers for predicting each POP exposure with 100% accuracy. The data from large-scale gene expression analysis of a different POP exposure in rat model suggest that characteristic expression profiles exist in liver hepatic cells and multiclassification of POP-specific molecular signatures can discriminate each toxicant at an early exposure time. The use of these molecular markers may be more widely implemented in combination with more traditional techniques for assessment and prediction of toxicity exposure to POPs from an environmental aspect.</P>
Inflammatory Pseudotumor of Splenic Hilar Node Mimicking Gastric Submucosal Tumor
Jung Min Bae,Se Won Kim,Sang Woon Kim,Sun Kyo Song 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.78 No.3
Inflammatory pseudotumor (IPT) is an uncommon clinical condition characterized by proliferation of spindle cells, inflammatory cells, and small vessels. IPT has been reported in various anatomical sites, including the orbit, lung, liver, spleen, and so on. IPT of the lymph node is very rare. We recently experienced a 65-year-old woman diagnosed with IPT of the lymph node in the splenic hilar, or distal supra-pancreatic area, mimicking gastric submucosal tumor. The tumor was removed without event using the laparoscopic method. This lesion in the splenic hilum is extremely rare and has not been cited in the current literature. We describe such a rare case of IPT with a review of the literature.