Formation of Poly(vinyl alcohol)/SWNTs Fibers with Hierarchical Structure under High-Speed Shear Flow

Xia Wang,Changcun Wu,Jun Sun,Chuanxiang Qin,Jianjun Wang,Qiqi Zhuo,Lixing Dai 한국섬유공학회 2020 Fibers and polymers Vol.21 No.5

This study introduces a facile method to prepare syndiotactic poly(vinyl alcohol) (s-PVA) fibers containing singlewalledcarbon nanotubes (SWNTs) from the corresponding composite dispersions with tea polyphenols (TP) as dispersantunder high-speed shear flow. The formation of the composite fibrous precipitates at high shear rate is largely facilitated by theSWNTs in the dispersions and slight flow resistance. Interestingly, the obtained s-PVA/SWNTs composite precipitatespossess a three-level hierarchical structure, that is, a single fiber is assembled by fibrils which are composed of microfibrils ofs-PVA-coated SWNTs. And the s-PVA fibrous precipitates containing high amounts of SWNTs could be obtained by shearingthe dispersion with relatively low SWNTs loadings, as a result, the composite fiber containing 20.7 wt% SWNTs wasprepared from the dispersion with 10.0 wt% SWNTs. In addition, with the increase of SWNTs loadings, the amount of theprecipitates increases, but crystallinity of the precipitates decreases instead.

A Theoretical Study of Knowledge Utilization in Policymaking and Practice in China

( Wang Jun Xia ) 한국정책학회 2011 International Journal of Policy Studies Vol.2 No.2

Public policy fairness relies on judgmatical policymaking process based upon if prescient opinions about the policy were adequately collected, integrated and adopted. Good policy should be supported by collective intelligence and wisdom. Thus, knowledge utilizing is a decisive factor to determine public policy fairness. This paper focuses on the knowledge utilization mechanism in policymaking process. It first summarizes the present research of knowledge utilization theory in the policymaking process and classifies policymaking knowledge into four types. After that, it analyzes the features of these four types of knowledge and indentifies the knowledge owners that will attend to policymaking. Then it puts forwards some criterions that assess the knowledge utilizing in policymaking. Finally, it scans China`s practice and evaluates China`s performance of knowledge utilization in the policymaking process, explores the reasons and presents corresponding solutions.

Clinical Impact of Drug Adherence of Tyrosine Kinase Inhibitors in Children with Ph-Positive Acute Lymphoblastic Leukemia

Jun-Xia Wang,Miao-Miao Yang,Li-Peng Liu,Hui-Min Zhang,Meng-Chuan Wang,Yu-Wen Chen,Xiao-Ying Zang,Fang Hu 대한암학회 2023 Cancer Research and Treatment Vol.55 No.3

Purpose This study aimed to explore the impact of ABL1–tyrosine kinase inhibitors (TKIs) adherence on the survival of chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) children and clarify the potential predictors of patients’ prognosis from TKIs intake practices.Materials and Methods Ninety newly diagnosed Ph+ ALL patients who received TKIs were enrolled. We collected the baseline characteristics and adverse events in all children; moreover, TKIs adherence was measured by an eight-item Morisky medication adherence scale (MMAS-8). Progression-free survival (PFS) and overall survival (OS) analysis were performed, and risk factors for PFS and OS were evaluated.Results Among all patients, 69 cases were regarded as adherers, while 21 were non-adherers. The median duration of TKIs interruption was significantly prolonged in the non-adherence group than in the adherence group (13 [0-101] vs. 56 [11-128], p < 0.001). Additionally, dose reduction occurred in 55.2% of non-adherers versus 23.0% of adherers (p=0.002). The PFS and OS in adherers were significantly higher versus non-adherers (p=0.020 and p=0.039). MMAS-8 score was an independent risk factor for PFS (p=0.010) and OS (p=0.031). Among non-adherers, the median OS was only 23.1% (4.2%-42%) in patients aged ≤ 10 years versus 54.4% (38.8%-70%) in adolescents. Most of the patients who experienced TKIs non-adherence suffered pancytopenia.Conclusion TKIs adherence during treatment significantly influenced the survival of pediatric Ph+ ALL patients, and non-adherers with age ≤ 10 years were more vulnerable to TKIs disruption. The cumulative TKIs dose should be especially emphasized to patients with age ≤ 10 years, which may result in an inferior achievement of relevant treatment milestones.

Parkinson’s Disease with Fatigue: Clinical Characteristics and Potential Mechanisms Relevant to α-Synuclein Oligomer

Li-Jun Zuo,Shu-Yang Yu,Fang Wang,Yanghui Xia,Ying-Shan Piao,Yang Du,Teng-Hong Lian,Rui-Dan Wang,Qiu-Jin Yu,Ya-Jie Wang,Xiao-Min Wang,Piu Chan,Sheng-Di Chen,Yongjun Wang,Wei Zhang 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.2

Background and Purpose The aim of this study was to identify the clinical characteristics and potential mechanisms relevant to pathological proteins in Parkinson’s disease (PD) patients who experience fatigue. Methods PD patients (n=102) were evaluated using a fatigue severity scale and scales for motor and nonmotor symptoms. The levels of three pathological proteins—α-synuclein oligomer, β-amyloid (Aβ)1-42, and tau—were measured in 102 cerebrospinal fluid (CSF) samples from these PD patients. Linear regression analyses were performed between fatigue score and the CSF levels of the above-listed pathological proteins in PD patients. Results The frequency of fatigue in the PD patients was 62.75%. The fatigue group had worse motor symptoms and anxiety, depression, and autonomic dysfunction. The CSF level of α-synuclein oligomer was higher and that of Aβ1-42 was lower in the fatigue group than in the non-fatigue group. In multiple linear regression analyses, fatigue severity was significantly and positively correlated with the α-synuclein oligomer level in the CSF of PD patients, after adjusting for confounders. Conclusions PD patients experience a high frequency of fatigue. PD patients with fatigue have worse motor and part nonmotor symptoms. Fatigue in PD patients is associated with an increased α-synuclein oligomer level in the CSF

Molecular Mechanism of Plant Growth Promotion and Induced Systemic Resistance to Tobacco Mosaic Virus by Bacillus spp.

Shuai Wang,Hui Jun Wu,Jun Qing Qiao,Ling Li Ma,Jun Liu,Yan Fei Xia,Xue Wen Gao 한국미생물 · 생명공학회 2009 Journal of microbiology and biotechnology Vol.19 No.10

Complete ¹H-NMR and <SUP>13</SUP>C-NMR spectral assignment of five malonyl ginsenosides from the fresh flower buds of Panax ginseng

Yu-Shuai Wang,Yin-Ping Jin,Wei Gao,Sheng-Yuan Xiao,Yu-Wei Zhang,Pei-He Zheng,Jia Wang,Jun-Xia Liu,Cheng-He Sun,Ying-Ping Wang 고려인삼학회 2016 Journal of Ginseng Research Vol.40 No.3

Background: Ginsenosides are the major effective ingredients responsible for the pharmacological effects of ginseng. Malonyl ginsenosides are natural ginsenosides that contain a malonyl group attached to a glucose unit of the corresponding neutral ginsenosides. Methods: Medium-pressure liquid chromatography and semipreparative high-performance liquid chromatography were used to isolate purified compounds and their structures determined by extensive one-dimensional- and two-dimensional nuclear magnetic resonance (NMR) experiments. Results: A new saponin, namely malonyl-ginsenoside Re, was isolated from the fresh flower buds of Panax ginseng, along with malonyl-ginsenosides Rb1, Rb2, Rc, Rd. Some assignments for previously published ¹H- and <SUP>13</SUP>C-NMR spectra were found to be inaccurate. Conclusion: This study reports the complete NMR assignment of malonyl-ginsenoside Re, Rb₁, Rb₂, Rc, and Rd for the first time.

A novel planar motion generation method based on the synthesis of planetary gear train with noncircular gears

Jun Ye,Xiong Zhao,Ying Wang,XinCheng Sun,JianNeng Chen,XuDong Xia 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.10

Four-bar linkage has been used in motion generation synthesis for a long time, but there are inevitably some shortcomings such as order defects and poor design flexibility. In this work, a planetary gear train with noncircular gears is proposed to realize planar motion generation synthesis. Compared with the four-bar linkage, it has the advantages of a compact structure, full rotatability, and flexible design. The planetary gear train with noncircular gears is composed of two interrelated parts: a two-stage noncircular gear pair and the RR dyad. The synthesis method is divided mainly into three steps: First, the constraint equation of RR dyad for planar motion generation is established, and a solution region of the double revolute joint (RR) dyads is calculated by kinematic mapping theory. Second, after the full rotatability identification of RR dyads and the determination of each transmission ratio, the centrodes of two-stage noncircular gear pairs, which correspond to the specific RR dyad, are obtained. Finally, the planetary gear train with noncir-cular gears is established to pass the given poses. This method has a universal significance and can be applied to many practical cases.

High-Temperature Deformation Behavior and Processing Map of 7050 Aluminum Alloy

Jun-song Jin,Xin-yun Wang,H. E Hu,Ju-chen Xia 대한금속·재료학회 2012 METALS AND MATERIALS International Vol.18 No.1

The high-temperature deformation behavior and processing map of 7050 aluminum alloy were investigated by tensile tests conducted at various temperatures (340, 380, 420, and 460 °C) with various strain rates of 10−4, 10−3, 10−2, and 0.1 s −1. The results show that the instability region with a peak power dissipation efficiency of 100% occurs at the low deformation temperature region of 340 °C to 380 °C and high strain rates (>10−3s−1). The 7050 aluminum alloy exhibited a continuous dynamic recrystallization domain with power dissipation efficiency of 35% to 60 % in the deformation temperature range of 410 °C to 460 °C and the strain rate range of 10−4-10−3s−1. The domain with a power dissipation efficiency of 35 % to 50 % occurring at high deformation temperatures and strain rates was interpreted to represent dynamic recovery. Dynamic recovery and continuous dynamic recrystallization provide chosen domains for excellent hot workability.

Variation of cassiicolin genes among Chinese isolates of Corynespora cassiicola

Jun Wu,Xue-Wen Xie,Yan-Xia Shi,A-Li Chai,Qi Wang,Bao-ju Li 한국미생물학회 2018 The journal of microbiology Vol.56 No.9

Corynespora cassiicola is a species of fungus that is a plant pathogen of many agricultural crop plants, including severe target spot disease on cucumber. Cassiicolin is an important effector of pathogenicity of this fungus. In this study, we collected 141 Corynespora isolates from eighteen hosts, and the casscolin gene was detected in 82 C. cassiicola strains. The deduced protein sequences revealed that 72 isolates contained the Cas2 gene, two strains from Gynura bicolor harboured the Cas2.2 gene, and 59 isolates without a cassiicolin gene were classified as Cas0. Phylogenetic analyses was performed for the 141 isolates using four loci (ITS, ga4, caa5, and act1) and revealed two genetic clusters. Cluster A is composed of four subclades: subcluster A1 includes all Cas2 isolates plus 18 Cas0 strains, subcluster A2 includes the eight Cas5 isolates and one Cas0 isolate, and subclusters A3 and A4 contain Cas0 strains. Cluster B consists of 21 Cas0 isolates. Twenty-two C. cassiicola strains from different toxin classes showed varying degrees of virulence against cucumber. Cas0 or Cas2 strains induced diverse responses on cucumber, from no symptoms to symptoms of moderate or severe infection, but all Cas5 isolates exhibited avirulence on cucumber.

Thermodynamics stability, electronic structures and spectroscopic properties of defects and Ce3+ ions in Y2O3

Wang Yan,Wen Jun,Zheng Jiangyun,Deng Zhifeng,Zhou Yueyu,Jiang Guisheng,Xia Qiangsheng,He Enjie,Ning Lixin 한국물리학회 2021 Current Applied Physics Vol.26 No.-

Thermodynamic properties, electronic structures and spectroscopic properties of defects and Ce3+ in Y2O3 are studied by using the hybrid density functional theory associated with multi-reference configuration interaction ab-initio calculations. Thermodynamic transition energy levels of the easily generated oxygen vacancies in the host are analyzed according to HSE06-calculated formation energies, which may be conducive to interpretations of the persistent luminescence (PersL) of Y2O3-based phosphors. Besides, the locations of impurity states (caused by VO and Ce3+) in energy bands are obtained from derived density of states. Moreover, energies and oscillator strengths of 4f1 → 5d1 5 transitions of Ce3+ ions (at Y1 and Y2 sites) calculated from the CASSCF/CASPT2/ RASSI SO method agree reasonably well with experimental excitation spectra of Y2O3: Ce3+ phosphors, achieving the assignment of excitation spectra. The presented calculations can be applied to identify luminescent centers in Ce3+-doped phosphors and reveals possible native defects and their roles in the PersL of phosphors.