액취증 수술 후 상지운동 제한으로 인한 척골신경병증

정성노,임지현,권호,정상훈 大韓成形外科學會 2004 Archives of Plastic Surgery Vol.31 No.2

루프를 효과적으로 처리하는 PASC 프로세서 구조

지승현(Jee Sung Hyun),박노광(Park No Kwang),전중남(Jeon Joong Nam),김석일(Kim Suk Il) 한국정보처리학회 1999 정보처리학회논문지 Vol.6 No.5

This paper proposes PASC(PArtitioned SCeduler) processor architecture that equips with a number of functional unit and a individual scheduler pairs. Every scheduler of the PASC processor can determine whether a unit instruction can be issued to the associated functional unit or it is to be waited until next cycle caused by a resource collision or data dependencies. In the PASC processor, only the functional unit with a resource collision or data dependencies waits by executing a NOP(No Operation) instruction and the other functional units execute their own instructions. Therefore we can expect the code compaction effect on the PASC processor. Thus, the last instruction of a loop at certain iteration and the very first instruction of the loop at the next iteration can be scheduled simultaneously if the two instructions do not incur any resource collision or data dependencies. Therefore, we can expect that such two instructions without any resource collision and data dependencies are packed into the same very long instruction word and thus, the two instructions are executed concurrently at run time. As a result, we can shorten execution cycles of a loop comparing to the execution of the loop on a traditional VLIW or SVLIW processor architecture. Simulation result also promises faster execution of loops on a PASC processor architecture than those on a VLIW and SVLIW processor architecture.

텍스트 마이닝을 통한 한국 전통 디자인 인식에 관한 연구

노현지 ( No Hyun-jee ),구자준 ( Koo Ja-joon ) 커뮤니케이션디자인학회(구 시각디자인학회) 2019 커뮤니케이션 디자인학연구 Vol.69 No.-

오늘날의 디자인은 한 나라의 문화 콘텐츠가 그만의 독창성과 차별성을 확보하는데 핵심적인 역할을 수행한다. 이에 그동안 학계에서는 우리의 정체성을 담은 한국의 디자인을 융성하기 위해 학자들의 견해를 바탕으로 개념들을 제시해 왔으며, 이와 더불어 오늘날 현시대를 살아가는 대중들의 한국 전통 디자인에 대한 보편적 정체성과 그에 대한 인식 조사를 통해 새로운 시대의 철학, 기술, 감성과의 융합을 통한 혁신적문화 콘텐츠를 창조할 필요가 있다. 따라서 오늘날 한국 대중들의 마음속에 존재하는 한국 디자인의 정체성을 확인하고 한국 전통 디자인이 어떻게 인식되고 있는지를 파악할 필요가 있으며, 이를 4차 산업혁명을 이끄는 핵심기술 중의 하나인 빅데이터 텍스트 마이닝을 활용하여 분석해 보고자 한다. 이에 빅데이터 수집 및 분석 오픈소스 프로그램 UCINET을 사용하여 2018년 7월 24일~2019년 7월 24일 사이의 주요 포털사이트에서“한국 전통 디자인”에 대한 원문데이터를 수집하였다. 추출된 총 46939개의 키워드 중 불필요한 단어는 제외하고 문서 중 출현빈도 상위 39개의 키워드를 대상으로 하여 상세한 분석을 실시하였다. 중심성 분석, TF-IDF, CONCOR, NETWORK 분석 등 다양한 기법을 사용해 주제에 대해 다각도에서 분석을 시도하였다. 그 결과 ‘한국’,‘연구’,‘전통’,‘문화’의 키워드 들이 주요 키워드로 분석되었다. 이러한 연구결과는 대중들이 한국 전통 디자인에 대한 호기심을 갖고 있으며 그에 따른 연구가 필요하다는 것을 방증하고 한국 전통 디자인과 관련하여 문화적 측면을 중요하게 인식하고 있음을 알 수 있다. 이와 더불어 본 연구는 한국의 디자인에 대한 객관적인 기초자료를 제공하는 것에 이바지할 수 있을 것으로 기대된다. Today's design plays a key role in ensuring that a country's cultural content has its own uniqueness and differentiation. In the meantime, the academic community has presented the concepts based on the opinions of scholars in order to foster the Korean design that contains our identity. It is necessary to create innovative cultural contents through the fusion of philosophy, technology and emotion of the times. Therefore, it is necessary to confirm the identity of Korean design that exists in the minds of the Korean public today and how Korean traditional design is recognized, and analyze it using big data text mining, one of the key technologies leading the Fourth Industrial Revolution. Thus, using the open source program UCINET, big data collection and analysis, the original text data on "traditional Korean design" was collected from major portal sites between July 24, 2018 and July 24, 1919. Out of the total 46939 keywords extracted, unnecessary words were excluded and detailed analysis was conducted on the top 39 keywords in the document. A variety of techniques were used, such as centrality analysis, TF-IDF, CONCOR, and NETWORK analysis, to try to analyze the subject from various angles. As a result, keywords for 'Korea,' 'Study,' 'traditional' and 'Culture' were analyzed as major keywords. These findings demonstrate that the public is curious about Korean traditional design and that it needs to be studied accordingly, and recognize cultural aspects as important in relation to Korean traditional design. In addition, the study is expected to contribute to providing objective basic data on Korean design.

중증 태변착색아의 예후판정에 있어 태아 심박자궁수축 검사의 유용성

박지현(Jee Hyun Park),임영구(Young Goo Lim),임문환(Moon Hwan Lim),송은섭(Eun Sub Song),노인화(In Hwa No),이병익(Byung Ik Lee),김종화(Jong Hwa Kim) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.12

Objectives : The purpose of this study was to investigate the efficacy of intrapartal fetal cardiotocogram for prediction of adverse neonatal outcome in pregnancy with thick meconium stained amniotic fluid during labor. Methods : This study included 130 pregnant women with intrapartal thick meconium stained amniotic fluid among 4,623 pregnant wemen admitted to the department of obstetrics and gynecology, Inha University hospital from October 1, 1996 to June 30, 1999. We analyzed the fetal heart rate(FHR) tracing at least two 30-minute segments whenever possible during the active phase of first stage. Neonates were considered to have adverse outcome if they were required oxygen support, had low 5minute apgar score(<7) and significant complications such as sepsis, aspiration pneumonia, seizure in first 24hours. These data were examined retrospectively the maternal and neonatal in-hospital chart, electronic FHR monitoring strips and recorded data. The data were analyzed by SAS computer program. Results : 1)The overall incidence of thick meconium stained amniotic fluid among total birth was 2.8%. 2)The obstetric characteristics in thick meconium stained pregnancies were high incidence of primigravity(70%) and operative delivery(61.6%) such as cesarean section, vacuum extraction. 3)The incidence of adverse neonatal outcome in thick meconium stained pregnancy was 19.2%. 4)The patients in whom abnormal fetal heart rate patterns accompany the passage of thick meconium had high incidence of adverse neonatal outcome (88%). Especially, late deceleration and decreased beat to beat variability were related adverse neonatal outcome(odds ratio 19.6 vs 30.8). Conclusion : We suggested that intrapartal fetal cardiotocogram was one of the useful methods for prediction of adverse neonatal outcome in thick meconium stained amniotic fluid. Especially, late deceleration and decreased beat to beat variability accompany the passage of thick meconium was considered high risk conditions and required careful interventions.

History-indicated cerclage: the association between previous preterm history and cerclage outcome

( Kyong-No Lee ),( Eun-Jee Whang ),( Kylie Hae-Jin Chang ),( Ji-Eun Song ),( Ga-Hyun Son ),( Keun-Young Lee ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.1

Objective Our hospital's policy is to perform history-indicated cerclage (HIC) for pregnant patients with 1 or more second-trimester pregnancy losses. Recently, the American College of Obstetricians and Gynecologists (ACOG) guideline regarding indications for HIC was changed from 3 or more previous second-trimester fetal losses to one or more. In this study, we aimed to evaluate the efficacy of the revised guideline and to investigate the association between previous preterm history and cerclage outcome. Methods We conducted a retrospective observational study of cases of HIC in singleton pregnancies performed at our hospital between January 2007 and June 2016. We compared the perioperative complications and incidences of preterm delivery in patients with one previous second-trimester pregnancy loss against those in patients with ≥2 losses. Results The incidence of preterm delivery (<32 weeks) was significantly lower in patients with one previous second-trimester pregnancy loss than in those with ≥2 losses (15/194 [8%] vs. 28/205 [14%]). In the 1 loss and ≥2 losses groups, the rates of preterm premature rupture of membranes (PPROM) were 7% and 8%, the rates of PPROM at <32 weeks 2.1% and 3.4%, and the ratios of neonatal intensive care unit admission 10% and 17%, respectively. Conclusion Comparison of HIC in one previous second-trimester pregnancy loss group with HIC in the 2 or more previous second-trimester pregnancy loss group found no difference in pregnancy outcome. This finding supports the amended ACOG guideline for HIC indications. Based on our results, we also propose development of a new protocol for HIC-related complications.

음향방출을 이용한 Type-3 수소연료탱크의 피로손상 연구

지현섭(Hyun-Sup, Jee),이종오(Jong-O, Lee),주노회(No-Hoe, Ju),김은정(Eun-Jung, Kim) 한국가스학회 2013 한국가스학회 학술대회논문집 Vol.2013 No.5

유리섬유강화 복합재료 가스실린더의 복합재료 파괴시 발생하는 음향방출 특성

지현섭(Hyun-Sup Jee),이종오(Jong-O Lee),주노회(No-Hoe Ju),소철호(Cheal Ho So),이종규(Jong-Kyu Lee) 한국비파괴검사학회 2013 한국비파괴검사학회지 Vol.33 No.5

본 연구에서는 유리섬유강화 복합재료 가스실린더의 복합재료의 파괴시 발생하는 음향방출신호의 특성을 살펴보기 위하여 실린더의 외부를 감싸고 있는 복합재료를 유리섬유묶음과 시편으로 가공하여 파괴시험을 실시하였다. 유리섬유묶음에 칼날을 압입하여 유리섬유가 파괴될 때 발생한 음향방출 신호의 진폭은 칼날의 절단각도가 커짐에 따라 유리섬유의 절단면이 증가되어 음향방출신호의 진폭이 증가되는 것으로 판단된다. 또한 복합재료 시편파괴시 감긴방향 파괴는 수직방향 파괴에 비해 hit 수는 적지만 섬유 절단각이 커짐에 따라 진폭은 높게 나타났다. 섬유감긴방향으로 시편파괴시 신호문턱값을 32 dB로 설정했을 경우는 40 dB로 설정했을 때는 나타나지 않았던 기지파괴 신호가 급격하게 나타나는 것으로 보아 기지파괴시 신호진폭은 40 dB 이하이고 유리섬유 파괴신호의 진폭은 40 dB이상 임을 알 수 있었다. 음향방출 신호의 진폭기울기는 음향방출원과 관련이 있으며, 섬유감긴방향으로 칼날을 압입했을 때 그 기울기는 0.08이고 수직방향일 때는 0.16로 구분되었다. 특히 수직방향 파괴의 경우 유리섬유묶음의 절단시 나타나는 진폭 기울기와 유사하여 시편의 수직방향파괴시 발생하는 신호의 주 음향방출원은 유리섬유파괴로 추정할 수 있다. This study is investigation of the characteristics for acoustic emission signal generated by destruction on glass fiber bundles and specimen that was machined composite materials surrounding the outside of GFRP cylinder. The Amplitude of acoustic emission signal gets bigger as the cutting angle of knife increases. Accordingly, the number of hits in destruction of composite materials specimen have more in longitudinal direction (longitudinal direction to the glass fiber) than in hoop direction (horizontal direction to the glass fiber) while the amplitude of signals were bigger in hoop direction than longitudinal direction. It was found out that the amplitude of the glass fiber breakage is more than 40 dB and that the amplitude of signal for matrix crack was less than 40 dB because matrix crack signal was not observed when threshold value is 40 dB and matrix crack signal suddenly appered when threshold value is 32 dB. The slope of the amplitude is related to the acoustic emission source and the slope of the amplitude of the horizontal and vertical directions are 0.16 and 0.08. In particular, The slope of the amplitude of longitudinal direction breakage appear similar to the glass fiber breakage and therefore Acoustic emission source of longitudinal direction breakage is estimated the glass fiber breakage.

피로시험시 발생하는 음향방출신호를 이용한 Type Ⅱ Gas Cylinder의 손상평가

지현섭(Hyun Sup Jee),이종오(Jong O Lee),주노회(No Hoe Ju),소철호(Cheal Ho So),이종규(Jong Kyu Lee) 한국가스학회 2012 한국가스학회지 Vol.16 No.2

본 연구는 Type Ⅱ가스실린터의 20,000 회 피로시험과 파열시험시 음향방출시험을 병행하여 용기의 손상정도를 평가하고자 하였으며, 실험에 사용된 용기는 결함 크기가 3 mm×3 mm×50 mm (폭×깊이×길이)이고 결함 방향이 용기의 종방향 및 횡방향인 인공결함용기와 건전한 용기 등 세 종류이다. 피로시험시 발생된 음향방출신호는 종방향결함의 경우 전체 신호 중 결함에서 발생된 이벤트의 비율이 50 % 이상이며, 음향방출신호의 위치표정도 매우 정확하게 일치하였다. 또한 파열시험에서는 인공결함용기가 결함 위치에서 에상파열압력보다 낮은 압력으로 파열될거라는 예상과는 달리 인공결함용기의 파열압력은 건전한 용기와 큰 차이가 없었으며, 단지 종방향 인공결함용기의 경우 파열위치가 결함 위치와 근접하게 발생하였다. 이는 종방향 결함의 길이만큼 복합재료의 두께가 얇아지는 효과로 나타나게 되어 금속라이너의 피로반복시 결함 발생과 성장위치에 영향을 미친 것으로 판단된다. This research seeks to evaluate damage on type Ⅱgas cylinder by an acoustic emission test when executing 20000 cycles fatigue test and thereafter burst test. Used gas cylinders in the experimental are three types as follows; one is sound cylinder, others are cylinders which contain longitudinal and transverse artificial defect. The size of artificial defect is a depth of 3 mm, width of 3 mm and length of 50 mm. In the case of the cylinder which artificial defect, unlike the expectation that it will burst in low pressure, the burst pressure of the cylinder did not differ much according to whether or not there were defects. However, when there was longitudinal defect, the location of burst was near the location of defect. This leads to the effect in which the thickness of the composite material becomes thinner according to the length of the longitudinal defect and this is judged to have an effect on the location of initiation and growth of crack in the liner. Also, for the acoustic emission signal, when there is longitudinal defect, the ratio of an event occurring at defect position among overall hits is more than 50 %, and the source location also accords very precisely with defect position.

인체위암세포주(AGC)의 증식에 미치는 lovastatin의 억제효과

김지연,김성훈,서수홍,최병주,김현영,노치환,김동완,김기환,박무인,구자영 고신대학교 의학부 2002 高神大學校 醫學部 論文集 Vol.17 No.1

Background At the first step of cholesterol synthesis, 3-hydroxy-3-methylglutaryl-CoA reductase(HMG-CoA reductase) catalyzes the formation of mevalonate, which is the precusor of isoprenoid moieties that are incorporated into or linked to several molecules for cell growth and replication, which include Ras, Rho, G proteins and nuclear laminin B. Lovastatin(mevinolin), as an inhibitor of HMG-CoA reductase, blocks mevalonate synthesis, by which also prevents the isoprenylation of several proteins such as Ras, display antitumor effect in experimental models. In the present study the effects of lovastatin on the growth of human gastric carcinoma cell line, AGS cells were examined and the effects of 5-fluorouracil(5-FU) were also studied. Cell cycle analysis was done to examine the mechanisms for the inhibitory effects of lovastatin. Methods The growth of AGS cells were examined by counting cell number on one and three days treatment with 0.2umol/L, 0.4umol/L, 0.8umol/L, 1.6umol/L, 3.2umol/L lovastatin, and 0.1umol/L, 0.3㎍/㎖ 5-FU, after plating AGS cells into 35㎚^(2) plastic dishes at a density of 10*10^(4) cells/dish. The reversibility of the effects of lovastatin was examined on one day to seven days treatment with 0.8u㏖/L lovastatin after seeding 10*10^(4) cells/dish. To examine the mechanisms for the inhibitory effects of lovastatin, cell cycle analysis was done on the cells after four days treatment with 0.8u㏖/L lovastatin. Results Lovastatin significantly inhibited the growth of AGS cells in a dose-dependent fashion(p<0.05). Forth-eight percent inhibition of growth was found at an lovastatin concentration of 0.8umol/L and ninety-three percent inhibition of growth was found at an lovastatin concentration of 3.2umol/L after 4 days treatment. The inhibitory effect of lovastatin on the growth of AGS cells was firstly shown at the concentration of 0.4umol/L. The removal of lovastatin by a media change after 24 hours treatment of lovastatin was note different from that of control group, which was not treated by lovastatin. Lovastatin combined with 5-FU significantly inhibited the growth of AGS cells in a dose-dependent fasion compared to lovastatin or 5-FU alone(p<0.05), which suggested additive effect of the two drugs. After four days treatment with 0.8umol/L lovastatin, the fraction of cells in G0-G1 phase, S phase and G2-M phase was 51.5%, 31.5%, 17.0% respectively in the control group, and 50.6%, 32.6%, 16.7% in the lovastatin group(0.8umol/L), showing no significant differences between the two. Conclusions Lovastatin significantly inhibited the growth of AGS cells in a dose-dependent fashion, The inhibitory effect for lovastatin on the growth of AGS cells was reversible since the growth of AGS cells after removal of lovastatin by a media change after 24-48hours treatment of lovastatin was note different from that of control group which was note treated by lovastatin. The reversibility of growth inhibition suggests that lovastatin is not a non-specific cytotoxin for AGS cells. This is the first report that lovastatin may be very useful for the treatment of gastric carcinoma, especially in conjunction with 5-FU, because the concentrations(0.2-3.2umol/L) used in our study were within the ranges of steady-state concentrations(0.15-0.3umol/L) attainable in human serum by chronic administration of maximum recommended dose(80/㎎/day) of lovastatin and additive effect of lovastatin and 5-FU. More studies by animal experiments and clinical trials are needed to establish lovastatin as an anticancer drug for human gastric carcinoma.

¹ H-NMR-Based Metabolomics Study of Cerebral Infarction

Jung, Jee Youn,Lee, Ho-Sub,Kang, Dae-Gill,Kim, No Soo,Cha, Min Ho,Bang, Ok-Sun,Ryu, Do Hyun,Hwang, Geum-Sook Ovid Technologies Wolters Kluwer -American Heart A 2011 Stroke Vol.42 No.5