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      • KCI등재

        염분 수준이 육계 병아리의 생산성과 생리적인 변화에 미치는 영향

        황보종,홍의철,이병석,이현정,조성백,배해득,이성재,노환국,HwangBo J.,Hong E.C.,Lee B.S.,Lee H.J.,Jo Seong-Baek,Bae H.D.,Lee S.J.,Nho W.G. 한국가금학회 2006 韓國家禽學會誌 Vol.33 No.2

        본 연구는 사료와 음수에 함유된 염분 수준이 육계 초기 병아리에 미치는 영향을 조사하기 위하여 실시하였다. 1일령 초생추(Hubbard)를 공시하여 14일 동안 시험을 수행하였다. 시험 1에서, 사료내 염분 함량은 0, 0.25, 0.5, 0.75, 1.0, 2.0, 3.0, 4.0%로 조절하여 8처리구 처리구당 3반복, 반복당 12수씩 총 288수에 급여하였고, 시험 2에서, 음수내 염분 함 량은 0, 0.1, 0.2, 0.5, 1.0%로 조절하여 5처리구 처리구당 3반복, 반복당 12수씩 총 180수에 공급하였다. 시험 1의 경우에, 사료 섭취량과 증체량은 사료내 염분 함량이 증가할수록 감소하는 경향이었다. 특히 4% 처리구에서 각각 481 g과 168 g으로 가장 낮았으며, 폐사율은 75%로 가장 높았다. 시험 2의 경우에는, 음수 1% 처리구에서 사료 섭취량과 증체량은 각각 427 g과 162 g이었고, 폐사율은 77.8%로 가장 높았다. 염 중독 증상을 나타낸 닭들은 갈증, 식욕부진, 기립불능, 졸림, 경련 등을 나타내었고, 부검 소견에서는 복수증, 심낭수종, 심비대, 각종 장기의 출혈 등이 나타났다. 이상의 결과로 육계 초기에서 사료내 염분 함량이 3%, 음수내 염분 함량은 1% 이상에서 뚜렷한 생산성의 저하는 물론 생리 해부학적인 염분중독 증상이 나타남을 알 수 있다. To investigate the effects of salt contents in diet and water on the growth of broiler chicks, 288 heads of Hubbards strain chicks, were fed with com-soybean meal diets containing 0, 0.25, 0.5, 0.75 1.0, 2.0, 3.0, or 4.0% salt from 1d to l4d posthatching. And 180 chicks were also supplemented with salt to their water at 0, 0.1, 0.2, 0.5 or 1.0%. Feed intake and weight gain tended to decrease as the salt levels in diets increased and those were the lowest in 4% group as 481 g and 168 g, however, mortality was the highest in 4% group as 75.0%. As for the salt levels in water, feed intake and weight gain were low as 427 g and 162 g in 1% group, while mortality was 77.8%. Salt poisoning chicks were shown with thirsty, appetite deficiency, rising impossibility, sleepiness, or convulsions, and in autopsy, were shown with ascites, hydropericardium, cardiac hypertrophy, hemorrhage of eyelid, hemorrhage of trachea, hemorrhage of intestine, etc. Conclusively, salt content above 4% in diet or 1% in water could reduce the performance in broiler chicks.

      • SCISCIESCOPUS

        Growth of Epitaxial MgB<sub>2</sub> Thick Films with Columnar Structures by Using HPCVD

        Seong, W. K.,Huh, J. Y.,Kang, W. N.,Kim, J.-W.,Kwon, Y.-S.,Yang, N.-K.,Park, J.-G. Wiley - VCH 2007 CHEMICAL VAPOR DEPOSITION -WEINHEIM- Vol.13 No.12

        <P>Epitaxial MgB<SUB>2</SUB> thick films are grown on Al<SUB>2</SUB>O<SUB>3</SUB> substrates at 600 °C by using the hybrid physical (HP)CVD technique. In order to obtain a high magnesium vapor pressure around the substrates, we use a special susceptor having a susceptor cap and achieve a very high growth rate of 0.17 &mgr;m min<SUP>–1</SUP>. Hexagonal-shaped columnar structures are observed by cross-sectional and planar-view transmission electron microscope (TEM) images. For the 1.7 &mgr;m thick film, the T<SUB>c</SUB> is observed to be 40.5 K with a J<SUB>c</SUB> of 1.5 × 10<SUP>6</SUP> A cm<SUP>–2</SUP> at 30 K. The vortex pinning mechanism by intercolumnar boundaries will be discussed.</P> <B>Graphic Abstract</B> <P>By using novel HPCVD technique with a special susceptor and a susceptor cap, epitaxial MgB<SUB>2</SUB> thick films with columnar structures are successfully fabricated at low temperatures (below 600 °C). The susceptor cap significantly enhances the local magnesium vapor pressure around the substrates so that a very high growth rate of 0.17 &mgr;m/min could be achieved. For the 1.7-&mgr;m-thick film, the T<SUB>c</SUB> was observed to be 40.5 K.</P>

      • Neuroprotective Effect of Human Adipose Stem Cell-Derived Extract in Amyotrophic Lateral Sclerosis

        Jeon, G. S.,Im, W.,Shim, Y. M.,Lee, M.,Kim, M. J.,Hong, Y. H.,Seong, S. Y.,Kim, M.,Sung, J. J. Springer Science + Business Media 2016 Neurochem Res Vol.41 No.4

        <P>Amyotrophic lateral sclerosis (ALS) is a devastating human neurodegenerative disease. The precise pathogenic mechanisms of the disease remain uncertain, and as of yet, there is no effective cure. Human adipose stem cells (hASC) can be easily obtained during operative procedures. hASC have a clinically feasible potential to treat neurodegenerative disorders, since cytosolic extract of hASC contain a number of essential neurotrophic factors. In this study, we investigated effects of hASC extract on the SOD1 G93A mouse model of ALS and in vitro test. Administration of hASC extract improved motor function and prolonged the time until symptom onset, rotarod failure, and death in ALS mice. In the hASC extracts group, choline acetyltransferase immunostaining in the ventral horn of the lumbar spinal cord showed a large number of motor neurons, suggesting normal morphology. The neuroprotective effect of hASC extract in ALS mice was also suggested by western blot analysis of spinal cord extract from ALS mice and in vitro test. hASC extract treatment significantly increased expression of p-Akt, p-CREB, and PGC-1 alpha in SOD1 G93A mouse model and in vitro test. Our results indicated that hASC extract reduced apoptotic cell death and recovered mutant SOD1-induced mitochondrial dysfunction. Moreover, hASC extract reduced mitochondrial membrane potential. In conclusion, we have demonstrated, for the first time, that hASC extract exert a potential therapeutic action in the SOD1 G93A mouse model of ALS and in vitro test. These findings suggest that hASC hold promise as a novel therapeutic strategy for treating ALS.</P>

      • Enhancement of the critical current density of MgB<sub>2</sub> thick films by Ag- and Cu-impurity layers

        Ranot, M.,Seong, W.K.,Jung, S.G.,Lee, N.H.,Kang, W.N.,Joo, J.H.,Zhao, Y.,Dou, S.X. North-Holland 2009 Physica. C, Superconductivity Vol.469 No.15

        We report on Ag and Cu doping in MgB<SUB>2</SUB> thick films using amorphous Ag- and Cu-impurity layers with various thicknesses, 4, 8, 16, and 32nm. Firstly, Ag- and Cu-impurity layers were deposited on Al<SUB>2</SUB>O<SUB>3</SUB>(0001) substrates at room temperature by using pulsed laser deposition system. Subsequently MgB<SUB>2</SUB> films were grown on the top of Ag or Cu/Al<SUB>2</SUB>O<SUB>3</SUB> substrates at 560 and 600<SUP>o</SUP>C by using hybrid physical-chemical vapor deposition. The effect of Ag and Cu doping as well as growth temperature on the microstructure and critical current density (J<SUB>c</SUB>) of MgB<SUB>2</SUB> films were investigated. It was found that both of Ag/Cu doping and low growth temperature can significantly enhance J<SUB>c</SUB> without suppression of T<SUB>c</SUB>. The increase in J<SUB>c</SUB> results from improved grain connectivity and strong flux pinning by high density of grain boundaries and other types of defects introduced by Ag- or Cu-impurity layers.

      • HECTOMAP AND HORIZON RUN 4: DENSE STRUCTURES AND VOIDS IN THE REAL AND SIMULATED UNIVERSE

        Hwang, Ho Seong,Geller, Margaret J.,Park, Changbom,Fabricant, Daniel G.,Kurtz, Michael J.,Rines, Kenneth J.,Kim, Juhan,Diaferio, Antonaldo,Zahid, H. Jabran,Berlind, Perry,Calkins, Michael,Tokarz, Susa American Astronomical Society 2016 The Astrophysical journal Vol.818 No.2

        <P>HectoMAP is a dense redshift survey of red galaxies covering a 53 deg(2) strip of the northern sky. HectoMAP is 97% complete for galaxies with r < 20.5, (g-r) > 1.0, and (r -i) > 0.5. The survey enables tests of the physical properties of large-scale structure at intermediate redshift against cosmological models. We use the Horizon Run 4, one of the densest and largest cosmological simulations based on the standard. Cold Dark Matter (Lambda CDM) model, to compare the physical properties of observed large-scale structures with simulated ones in a volume-limited sample covering 8 x 10(6) h(-3) Mpc(3) in the redshift range 0.22 < z < 0.44. We apply the same criteria to the observations and simulations to identify over-and under-dense large-scale features of the galaxy distribution. The richness and size distributions of observed over-dense structures agree well with the simulated ones. Observations and simulations also agree for the volume and size distributions of under-dense structures, voids. The properties of the largest over-dense structure and the largest void in HectoMAP are well within the distributions for the largest structures drawn from 300 Horizon Run 4 mock surveys. Overall the size, richness and volume distributions of observed large-scale structures in the redshift range 0.22 < z < 0.44 are remarkably consistent with predictions of the standard Lambda CDM model.</P>

      • KCI우수등재

        한우에 있어서 Rosette Inhibition Test 에 의한 조기 임신인자(Early Pregnancy Factor)의 검출

        성환후,백광수,고응규,신기준,박용윤,신원집 한국축산학회 1997 한국축산학회지 Vol.39 No.4

        Early pregnancy factor(EPF) is one of the pregnancy associated proteins, and it is detected in senun of many pregnant animals shortly after fertilization. The present study was conducted to establish a system of early pregnancy by EPF detection in Hanwoo cows. The EPF activity was measured by the rosette inhibition test on day 15 after artificial insemination or non-insemination. The rate of rosette formation between Hanwoo lymphocytes and sheep red blood cells was significantly(P$lt;0.05) higher compared to that between Hanwoo lymphocytes and goat, or rabbit red blood cells. The rosette formation between lymphocytes suspension and sheep red blood cells with anti-lymphocytes was not significantly(P$lt;0.05) changed until 5∼20 min. of culture, and then decreased dramatically by 30 min. There were significant(P$lt;0.05) differences in the rosette inhibition titer(RIT) between pregnant and non-pregnant Hanwoos on day 15 after artificial insemination. The results indicate that the expression of early pregnancy factor by the rosette inhibition test might be used to diagnosis of early pregnancy in Hanwoo.

      • KCI등재후보

        완전 이식형 인공중이의 국내 개발현황

        조진호,박일용,임형규,윤영호,성기웅,정의성,한지훈,김민규,이상흔 한국장애인재활협회 2006 재활복지 Vol.10 No.3

        인구의 고령화가 진행되면서 난청인구는 증가하고 있으며 난청자들은 일반적으로 공기전도형 보청기를 사용하고 있다. 이러한 보청기는 미용문제와 귀 폐쇄감 및 하울링 현상 등으로 인해 난청자들이 기피하고 있으며, 이를 극복하기 위한 방법으로 완전히 은닉할 수 있고 음향 피드백의 영향이 적은 완전 이식형 인공중이 시스템이 전 세계적으로 주목받고 있다. 경북대 첨단 감각기능 회복장치연구센터(Advanced Research Center for Recovery of Human Sensibility, ACRHS)는 보건복지부의 지원과 (주)파이컴의 참여 하에, 약 4년간의 연구 결과로 차동 전자 트랜스듀서를 기반으로 하는 완전 이식형 인공중이 시스템의 시제품 ACROHS-1.5와 그 주변장치로 무선 제어기 및 무선 충전장치를 각각 구현하고 실험을 통해 평가하였다. 현재는 제작된 시제품을 기반으로 한국식품의약품안전청 (KFDA)의 시험을 받기 위한 준비과정에 있다. Recently, persons who have difficulty in hearing are increase as aging of population, conventional hearing aids are generally used by them. In contrast with conventional hearing aids, implantable middle ear hearing devices (IMEHDs) with the advantages of complete concealment, occlusion of ear, and reduction of acoustic feedback are remarkable methods to overcome difficulties of people who have from moderate hearing loss to severe hearing loss. At Advanced Research Center for Recovery of Human Sensibility (ACRHS) in Kyungpook National University (KNU) under the auspices of Korean Ministry of Health & Welfare (KMHW) and PHICOM Co, as the products of their research during 4 years, fully implantable middle ear hearing device (ACROHS-1.5) based on a differential floating mass transducer (DFMT), an implantable microphone, a remote controller, and a wireless charger have been implemented. Each prototype has been evaluated through several experiments. In the present time, we are going to prepare clinical trials for approval of Korean Food and Drug Administration (KFDA).

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