http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Hyuk Jin Cha (검색결과 249 건)
- 무료
- 기관 내 무료
- 유료
-
김태우,김승범,권혁찬,문선재,윤정훈,김형준,차인호,육종인,김진 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.1
Periosteal osteosarcoma is a distinct entity of malignant bone tumor with characteristic clinical, morphological, and histological features within the group of juxtacortical osteosarcoma. Periosteal osteosarcoma is predominantly located in the tubular long bones, and extremely rarely involving the jaws. A case of periosteal osteosarcoma of the right mandible is presented. A 27-year-old woman complained of the gingival swelling and bleeding tendency of the right posterior mandible. Clinical examination revealed a reddish brown strawberry-like swelling on the affected mucosa, which measured 1.5㎝×1.5㎝. The tumor was located on the lingual cortex of the mandible and extended into the surrounding soft tissues. Microscopically, the tumor consisted exclusively of atypical chondroblastic cells with a small osteoblastic area. A minimal bone marrow involvement was noted and the adjacent cortex was free of tumor. These findings suggested that the tumor originated from the periosteal cambium layer, which lies between the periosteal fibrous layer and the cortex of mandible.
-
-
-
Hyuk Jin Cha,정태문,김형택,이종민 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.4
The realization of a tabletop X-ray free-electron laser (XFEL) based on a laser-plasma electron accelerator is a challenging scientific issue. A high-efficient undulator and a compact electron beam line, as well as a stable laser-plasma accelerator, are key elements for this form of state-of-theart synchrotron source. In particular, X-ray radiation in the water window spectral range is very attractive for biomedical applications due to its unique spectral characteristics. In this paper, we present numerical calculations and simulations for obtaining bright radiation in the water window spectral range from a prototype laser-plasma undulator source. Two compact undulators (planar and helical) and quadrupole-magnet doublets for electron beam focusing are considered. In our results, a helical undulator with a relatively low magnetic field strength shows beneficial radiation performance in terms of total power and on-axis angular flux density. The undulator radiation is then characterized based on its spectral brilliance deduced from an electron beam trajectory that was optimized using a quadrupole-magnet doublet. From the simulation results, the on-axis peak brilliance of the undulator radiation with a quadrupole-magnet doublet having a stronger magnetic field gradient (700 T/m), which can approach an electron source closer, was approximately three orders of magnitude higher than that of a case in which no doublet was used.
-
-
Transmission-Property Measurements of Crystal Quartz and Plastic Material in the Terahertz Region
Hyuk Jin Cha,Byung Cheol Lee,Seong Hee Park,박승한,Young Uk Jeong 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.1
To date, a few optical materials have been used for THz (terahertz) optics. The limited numbers of light sources developed in the THz region have resulted in a lack of optics. We have developed a compact high-power FEL (free-electron laser) operating in the frequency range of 0.3 3 THz, which is a powerful tool for investigating the optical properties of materials in the THz spectral range. We measured the transmittances of crystal quartz and plastic material by using the THz FEL. We discuss the dependence of transmission upon the polarization of the FEL beam and the effect of multiple-beam interference observed from a thin specimen. We also report data from FTIR (Fourier-transform infrared) spectroscopy of the materials in the THz region.l
-
-
-
-
Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c–SIRT2 axis
Cha, Young,Han, Min-Joon,Cha, Hyuk-Jin,Zoldan, Janet,Burkart, Alison,Jung, Jin Hyuk,Jang, Yongwoo,Kim, Chun-Hyung,Jeong, Ho-Chang,Kim, Byung-Gyu,Langer, Robert,Kahn, C. Ronald,Guarente, Leonard,Kim, K Nature Publishing Group 2017 NATURE CELL BIOLOGY Vol. No.
<P>A hallmark of cancer cells is the metabolic switch from oxidative phosphorylation (OXPHOS) to glycolysis, a phenomenon referred to as the 'Warburg effect', which is also observed in primed human pluripotent stem cells (hPSCs). Here, we report that downregulation of SIRT2 and upregulation of SIRT1 is a molecular signature of primed hPSCs and that SIRT2 critically regulates metabolic reprogramming during induced pluripotency by targeting glycolytic enzymes including aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, and enolase. Remarkably, knockdown of SIRT2 in human fibroblasts resulted in significantly decreased OXPHOS and increased glycolysis. In addition, we found that miR-200c-5p specifically targets SIRT2, downregulating its expression. Furthermore, SIRT2 overexpression in hPSCs significantly affected energy metabolism, altering stem cell functions such as pluripotent differentiation properties. Taken together, our results identify the miR-200c-SIRT2 axis as a key regulator of metabolic reprogramming (Warburg-like effect), via regulation of glycolytic enzymes, during human induced pluripotency and pluripotent stem cell function.</P>
RISS
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
