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윤명진,유덕기,홍영선,박석영,신완식,강문원,김춘추,김동집,정희영 대한감염학회 1985 감염 Vol.17 No.1
To reduce the death due to infection in leukemic patients, the pattern of infection, the factors affecting it, the site of infection and the spectrum of infecting organisms were evaluated retrospectively in 90 patients with various types of leukemia in the period from Jan. 1981 to Jun. 1984 at the St. Mary's hospital. The results were as follows. 1) Among the 90 patients, 29 were with ALL and the rest were with AML. Infection was the leading cause of death, even though bleeding had been the leading cause of death before the maintenance of platelet. 2) Fever was most frequently happened before and during the induction of remission and most of the fever was happened during the period of granulocyte count less than 500/㎣. 3) Upper and lower respiratory tract infection was the most frequent and as the causative organism, gram negative organism was shown in 39.4%, positive organism in 34.2%, candida in 21.1% and aspergillus in 7.9%. Pseudomonaswas the most frequent in gran negatives and Staphylococcus epidermidis was in gram positives. Rapid diagnosis, powerful treatment and the prevention of endogenous and exogenous infection are thought to be able to reduce the death due to infection in leukemic patients.
Induction Chemotherapy followed by Radiotherapy in Advanced Head and Neck Cancer
Kim, Dong Jip,Cho, Seung Ho,Moon, Hanlim,Lee, Kyung Shik,Yoon, Sei Chul,Kim, Min Sik,Hong, Young Seon,Kim, Hoon Kyo,Oh, Yoon Kyung,Suh, Byung Do CATHOLIC MEDICAL CENTER 1988 Bulletin of the Clinical Research Institute Vol.16/17 No.1
Untreated patients with head and neck cancer without distant metastasis underwent the induction chemotherapy followed by radiotherapy. Patient's age was ranged 34-70 (median 54); 7 were Stage Ⅲ, 19 Stage Ⅳ. Chemotherapy consisted of 3 cycles of cisplatin 100 mg/m^2 on day 1, and f-fluorouracil 1,000 mg/m^2/day for 5 days, every 3 or 4 weeks. Of 26 chemotherapy patients, 22 were evaluable ; complete response was 32% (7/22) and partial response 50% (11/22). Seventeen Patients completed radiotherapy following chemotherapy; complete response was 58.8% (10/17) and partial response 23.5% (4/17), The toxicities were tolerable. The induction chemotherapy using cisplatin and f-fluorouracil followed by radiotherapy was safe and effective.
황호윤(Ho-Yoon Hwang),김현홍(Hyun-Hong Kim),원종집(Jong-Jip Won),박종배(Jong-Bae Park),신중린(Joong-Rin Shin) 대한전기학회 2009 대한전기학회 학술대회 논문집 Vol.2009 No.7
For a similar price signal to local consumer, a regional clustering is important that can transfer a equal sign to the bus which has each different price on the basis of bus. If you take LMP and local information this method into consideration at the same time, and you give weight on neither one side, buses on a borderline can move on arbitrary. For solving this problem, in this paper will propose a clustering method to have applied new concept called 'electric distance'.
Cantera 기반의 실제 기체 상태 방정식을 고려한 steady flamelet 코드 개발
윤민경(Minkyeong Yoon),김홍집(Hong Jip Kim),김성구(Seong-Ku Kim) 한국연소학회 2021 KOSCOSYMPOSIUM논문집 Vol.2021 No.5
At high combustion pressure, oxidizer and fuel are supercritical or transcritical. Generalized equation of state can predict thermodynamic properties well from high to low compressibility. In this study, by using generalized equation of state, real steady flamelet code is developed, which can calculate flamelet considering real fluid effect.
Son, Hyun Shik,Hong, Kwan Soo,Yoo, Soon Jip,Kang, Moo Il,Son, Ho Young,Han, Je Ho,Cha, Bong Yun,Yoon, Kun Ho,Lee, Jong Min,Lee, Kwang Woo,Kang, Sung Ku CATHOLIC MEDICAL CENTER 1993 Bulletin of the Clinical Research Institute Vol.21 No.1
Autoimmune thyroid diseases, including Graves’ disease and Hashimoto’s thyroiditis, have been observed to occur in families. By population and family data on autoimmune thyroid disease, one or more disease susceptibility genes are known to be linked to the HLA-D region. Although the associations with the HLA-DR antigens appear to be strongest among those thus far reported, there are a variety of candidate genes in the HLA-D region that might influence susceptibility to autoimmune thyroid disease, including the loci that encode the DQ and DP molecules. The usefulness of non-radioactive oligonucleotide probes and possible genetic effects of HLA-DQA1 on the development of autoimmune thyroid disease were studied by analysis of polymerase chain reaction (PCR) and allele-specific oligonucleotide (ASO) probes of HLA- DQA1 directly labeled with horseradish-peroxidase at 5’ end. Peripheral lymphocyte DNA was obstained from 22 Korean patients with Graves’ disease, 21 patients with Hashimoto’s thyroiditis and 31 normal controls. Exon 2 of DQ chain gene was amplified by PCR procedure, hybridized to HLA-DQAI ASO probes. The frequency of allele Hybridizing to RH 83 probe which has common base sequence of DQA1 ^*0101, ^*0102 and ^*0103 was high (it was previously known as AI allele of HLA-DQ) and DQA1 ^*0201 was low in patients with autoimmune thyroid disease but it was not statistically significant. This result suggests that susceptibility to autoimmune thyroid disease is not related to HLA-DQA1 alleles in Korean patients with autoimmune thyroid disease and enhanced chemiluminescence method is safe, rapid and efficient one for signal detection.
아구창 치료에 있어 Clotrimazole ( Troches ) 과 Ketoconazole 의 효과
유승규(Seung Kew Yoon),이민상(Min Sang Yi),문한림(Han Lim Moon),홍영선(Yong Seon Hong),김훈교(Hoon Kyo Kim),이경식(Kyung Shik Lee),김동집(Dong Jip Kim) 대한내과학회 1987 대한내과학회지 Vol.34 No.1
N/A A randomized study was performed to compare the effect of clotrimazole troches and ketoconazole in the treatment of oral moniliasis. Eight patients who were treated with clotrimazole troches (10 mg 5 times a day for fourteen days) showed a resolution of symptoms and signs in 1.4 days after treatment initially and 3.0 days after treatment completely. In six cases with ketoconazole therapy (400 mg once a day p.o. for fourteen days), initial and complete clinical response were observed in 1.7 days and 5.0 days after treatment. No side effect was found in patients with clotrimazole troches group, while mild degree of nausea, anorexia and epigastric discomfort were developed in patients with ketoconazole group. These findings suggest clotrimazole troche is as effective as ketoconazole for oral moniliasis and more tolerable than latter.