프리스트레스트 콘크리트 橋梁의 解析 및 設計自動化

金亮均,李準熙,崔正鎬,申鉉穆 成均館大學校 科學技術硏究所 1995 論文集 Vol.46 No.2

Computer programs called "PCBRG" and "PCPST' were developed to analyze and design the prestressed concrete bridge. PCBRG is a structural analysis program which can determine the member forces, displacements and adaptable area of tendon by iteration method. PCPST is a post-processor for design. It enables design variables verified and the results of analysis (stress, member force and displacement, etc) are presented in the screen. Also the shear force and bending strength by the deformation compatibility method were checked.

전신마취 후 점액으로 인한 기관내관 폐쇄 : 증례보고 A case report

안기량,엄희상,김지은 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Nasotracheal intubation is commonly and safely used in the anesthetic management of patients undergoing oral cavity surgery. But endotracheal tube obstruction causes serious complications, including pneumothorax, pulmonary edema, brain injury and death. We experienced a case of endotracheal tube obstruction due to mucous crust after general anesthesia. A 5-year-old woman with cleft palate was intubated with a 4.5 mm amored tube for general anesthesia. During the surgery, vital signs were within normal limits. In the intensive care unit, she exhibited sign of complete airway obstruction. We exchanged the tube with another tube after failure of suction. The airway obstruction was due to a dried mucous crust attached to the bevel of the endotracheal tube. We should keep in mind the presence of an amored endotracheal tube cannot be regarded as a guarantee of a patent airway.

묵은 김치 제조과정에서의 이화학적 및 미생물학적 특성 변화

유맹자,김형량,정희종 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.5

To develop the low-temperature and long-term fermented kimchi, kimchi was prepared according to the recipe of a specific ratio of major and minor ingredients and adjusted its salinity to 3.7%. Prepared kimchi fermented at 15±1℃ for 24 hours and transferred and fermented in a refrigerator only used to make low-temperature and long-term fermented kimchi at -1±1℃ for 30 weeks. During 30 weeks of fermentation the changes in physicochemical and microbiological properties of low-temperature and long-term fermented kimchi were studied. The initial pH of 6.47 decreased gradually and dropped to pH 4.0 after 14 weeks of fermentation, and then it maintained at same level. Acidity increased to 0.49% on 2 weeks of fermentation and kept at 0.47∼0.50% during 2 to 30 weeks fermentation. Salinity was slightly increased at early stage and started to decrease on 4 weeks of fermentation, and then it did not change. The change of reducing sugar content was closely related to the trend of pH change with a very high correlation coefficient(r=0.912). Lactic acid, citric acid, malic acid, succinic acid and acetic acid were major organic acids contained in low-temperature and long-term fermented kimchi. Vitamin C content decreased at initial stage of fermentation and then slightly increased up to the maximum of 22.3㎎% on 8 weeks of fermentation. In color measurement, L value continued to increase during the fermentation and reached at the highest of 55.45 on 22 weeks of fermentation, and a and b values of 3.62 and 4.54 also increased to 31.26 and 37.32 on 30 weeks of fermentation, respectively. Total microbial count increased slowly from beginning and was the highest on 4 weeks of fermentation, and then began to decrease slowly. Count of lactobacillus spp. was highest after 6 weeks, but count of Leuconostoc spp. was highest on 2 weeks of fermentation, and then both showed a slow decrease. Yeast count wasn't increased until 4 weeks of fermentation and then increased rapidly to get the highest on 10 weeks of fermentation.

Severe ileus after colonoscopy in a patient on peritoneal dialysis

Kim, Sang Un,Kim, Su Hee,Hwang, So Yoon,Kim, Ryang Hi,Choi, Ji-Young,Cho, Jang-Hee,Kim, Chan-Duck,Kim, Yong-Lim,Park, Sun-Hee Yeungnam University College of Medicine 2017 Yeungnam University Journal of Medicine Vol.34 No.1

Peritoneal dialysis (PD) is associated with the development of various complications, such as exit site infection or peritonitis, and rarely, intestinal obstruction in prolonged PD patients with recurrent peritonitis. However, post-colonoscopy acute intestinal obstruction has not been reported in PD patients to date. Herein, we report a case of severe ileus after a colonoscopy without previous episodes of peritonitis in a PD patient. A 51-year-old man undergoing PD for 7 years visited our emergency department due to severe abdominal pain and vomiting after colonoscopic polypectomy. A simple abdominal radiography and abdominal computed tomography showed ileus with collapsed distal ileal loop. A peritoneal dialysate study revealed no evidence of peritonitis. The patient was treated with decompression therapy, and ileus was successfully treated without complications. This case suggests that it is not only necessary to prevent peritonitis, but also important to monitor the development of ileus after colonoscopy in PD patients.

<i>Shigella</i> Outer Membrane Protein PSSP-1 Is Broadly Protective against <i>Shigella</i> Infection

Kim, Jae-Ouk,Rho, Semi,Kim, Su Hee,Kim, Heejoo,Song, Hyo Jin,Kim, Eun Jin,Kim, Ryang Yeo,Kim, Eun Hye,Sinha, Anuradha,Dey, Ayan,Yang, Jae Seung,Song, Man Ki,Nandy, Ranjan Kumar,Czerkinsky, Cecil,Kim, American Society for Microbiology 2015 CLINICAL AND VACCINE IMMUNOLOGY Vol.22 No.4

<P>In developing countries, <I>Shigella</I> is a primary cause of diarrhea in infants and young children. Although antibiotic therapy is an effective treatment for shigellosis, therapeutic options are narrowing due to the emergence of antibiotic resistance. Thus, preventive vaccination could become the most efficacious approach for controlling shigellosis. We have identified several conserved protein antigens that are shared by multiple <I>Shigella</I> serotypes and species. Among these, one antigen induced cross-protection against experimental shigellosis, and we have named it pan-<I>Shigella</I> surface protein 1 (PSSP-1). PSSP-1-induced protection requires a mucosal administration route and coadministration of an adjuvant. When PSSP-1 was administered intranasally, it induced cross-protection against <I>Shigella flexneri</I> serotypes 2a, 5a, and 6, <I>Shigella boydii</I>, <I>Shigella sonnei</I>, and <I>Shigella dysenteriae</I> serotype 1. Intradermally administered PSSP-1 induced strong serum antibody responses but failed to induce protection in the mouse lung pneumonia model. In contrast, intranasal administration elicited efficient local and systemic antibody responses and production of interleukin 17A and gamma interferon. Interestingly, blood samples from patients with recent-onset shigellosis showed variable but significant mucosal antibody responses to other conserved <I>Shigella</I> protein antigens but not to PSSP-1. We suggest that PSSP-1 is a promising antigen for a broadly protective vaccine against <I>Shigella</I>.</P>

Low prealbumin levels are independently associated with higher mortality in patients on peritoneal dialysis

( Kyung Hee Lee ),( Jang Hee Cho ),( Owen Kwon ),( Sang Un Kim ),( Ryang Hi Kim ),( Young Wook Cho ),( Hee Yeon Jung ),( Ji Young Choi ),( Chan Duck Kim ),( Yong Lim Kim ),( Sun Hee Park ) 대한신장학회 2016 Kidney Research and Clinical Practice Vol.35 No.3

Background: Prealbumin, a sensitive marker for proteineenergy status, is also known as an independent risk factor for mortality in hemodialysis patients. We investigated the impact of prealbumin on survival in incident peritoneal dialysis (PD) patients. Methods: In total, 136 incident PD patients (mean age, 53.0 ± 15.8 years) between 2002 and 2007 were enrolled in the study. Laboratory data, dialysis adequacy, and nutritional parameters were assessed 3 months after PD initiation. Patients were classified into 2 groups according to prealbumin level: high prealbumin (
40 mg/dL) and low prealbumin (< 40 mg/dL). Results: The patients in the low-prealbumin group were older and had more comorbidities such as diabetes and cardiovascular diseases compared with the patients in the high-prealbumin group. Mean subjective global assessment scores were lower, and the high-sensitivity C-reactive protein levels were higher in the low-prealbumin group. Serum creatinine, albumin, and transferrin levels; percent lean body mass; and normalized protein catabolic rate were positively associated, whereas subjective global assessment scores and high-sensitivity C-reactive protein levels were negatively associated with prealbumin concentration. During the median follow-up of 49 months, patients in the lower prealbumin group had a higher mortality rate. Multivariate analysis revealed that prealbumin < 40 mg/dL (hazard ratio, 2.30; 95% confidence interval, 1.14e4.64) was an independent risk factor for mortality. In receiver operating characteristic curves, the area under the curve of prealbumin for mortality was the largest among the parameters. Conclusion: Prealbumin levels were an independent and sensitive predictor for mortality in incident PD patients, showing a good correlation with nutritional and inflammatory markers.

Severe ileus after colonoscopy in a patient on peritoneal dialysis

( Sang Un Kim ),( Su Hee Kim ),( So Yoon Hwang ),( Ryang Hi Kim ),( Ji-young Choi ),( Jang-hee Cho ),( Chan-duck Kim ),( Yong-lim Kim ),( Sun-hee Park ) 영남대학교 의과대학 2017 Yeungnam University Journal of Medicine Vol.34 No.1

Peritoneal dialysis (PD) is associated with the development of various complications, such as exit site infection or peritonitis, and rarely, intestinal obstruction in prolonged PD patients with recurrent peritonitis. However, post-colonoscopy acute intestinal obstruction has not been reported in PD patients to date. Herein, we report a case of severe ileus after a colonoscopy without previous episodes of peritonitis in a PD patient. A 51-year-old man undergoing PD for 7 years visited our emergency department due to severe abdominal pain and vomiting after colonoscopic polypectomy. A simple abdominal radiography and abdominal computed tomo-graphy showed ileus with collapsed distal ileal loop. A peritoneal dialysate study revealed no evidence of peritonitis. The patient was treated with decompression therapy, and ileus was successfully treated without complications. This case suggests that it is not only necessary to prevent peritonitis, but also important to monitor the development of ileus after colonoscopy in PD patients.

Plasma proGRP Concentration is Sensitive and Specific for Discriminating Small Cell Lung Cancer from Nonmalignant Conditions or Non-small Cell Lung Cancer

Kim, Hye-Ran,Oh, In-Jae,Shin, Myung-Geun,Park, Joon-Seok,Choi, Hyun-Jung,Ban, Hee-Jung,Kim, Kyu-Sik,Kim, Young-Chul,Shin, Jong-Hee,Ryang, Dong-Wook,Suh, Soon-Pal The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.5

<P>To date, most clinical data on pro-gastrin-releasing peptide (proGRP) have been based on serum concentrations. This study evaluated the agreement between proGRP levels in fresh serum and plasma in patients with various lung diseases. Pairs of serum and EDTA plasma were collected from 49 healthy individuals. At the same time, EDTA plasma of 118 lung cancer patients and 23 patients with benign pulmonary diseases were prospectively collected. Compared to serum, plasma proGRP concentrations were higher by an average of 103.3%. Plasma proGRP was higher in malignancy (336.4 ± 925.4 pg/mL) than in benign conditions (40.1 ± 11.5 pg/mL). Small cell lung cancer (SCLC) patients showed higher levels of proGRP (1,256.3 ± 1,605.6 pg/mL) compared to other types of lung cancer. Based on the ROC curve analyses at a specificity of 95%, the diagnostic sensitivity of plasma proGRP was estimated to be 83.8% in distinguishing SCLC from all the other conditions, and 86.5% for discriminating SCLC from the nonmalignant cases. Among the SCLC cases, limited stage disease had lower levels of plasma proGRP than extensive disease. When measuring circulating levels of proGRP, the use of plasma is preferred over serum. Plasma proGRP has a potential marker for discriminating SCLC from nonmalignant conditions or non-small cell lung cancer.</P>

Original articles : Comparison of processing times for isolation of feline adipose tissue-derived mesenchymal stem cells

( Hee Ryang Kim ),( Jienny Lee ),( Gyeong Been Lee ),( Jeong Su Byeon ),( Na Yeon Gu ),( In Soo Cho ),( Sang Ho Cha ) 한국예방수의학회(구 한국수의공중보건학회) 2015 예방수의학회지 Vol.39 No.3

Mesenchymal stem cells (MSCs) are an attractive source for cell therapy, as they have the potential for differentiation into multi-lineage cells. Adipose tissue is a safe source due to its easy extraction and abundant resource, with minimal risk to the organ donor. In this study, we attempted to correlate the harvest yield and resulting multipotency of feline adipose tissue-derived mesenchymal stem cells (fAD-MSCs) in accordance with processing time. fAD-MSCs were individually isolated from the abdominal adipose tissues of 6 felines. They were divided into two groups, based on their processing times - Group 1: 0~1 day after adipose tissue harvesting; Group 2: more than 3 days after adipose tissue harvesting. In both groups, the proliferation capacity was analyzed using the cumulative population doubling level (CPDL) calculation assay. The expression levels of MSC-specific markers and differentiation potentials into mesodermal cell lineages were also evaluated. We observed that fAD-MSC isolation yields and CPDL were excellent in Group 1 compared with Group 2. We also found that the differentiation potential-specific genes (ACAN and OPN) were strongly expressed in Group 1 compared with Group 2. These results suggest that for the clinical treatments of feline diseases, fAD-MSCs should be isolated within 1 day after adipose tissue harvesting.

Feline Adipose Tissue-Derived Mesenchymal Stem Cells

Hee Ryang Kim,Na Yeon Gu,Gyeong Been Lee,Jung Su Byeon,Geu Rim Kim,Jienny Lee,Sang Ho Cha 대한수의학회 2015 대한수의학회 학술대회발표집 Vol.2015 No.-