고속 중성자가 조사된 원자로 용기 강재의 운전온도에서의 Mossbauer 효과 연구

이경행,윤인섭,장기상 尙志大學校 1998 論文集 Vol.19 No.-

The changes of physical properities of the reactor vessel steel (SA 508 class 3) irradiated by fast neutron have been investigated by Mossbauer spectroscopy at operating temperature 600K. The various physical properties of the reactor vessel steel irradiated by neutron are changed because fast neutrons (over 1 MeV) are created in operating nuclear vessel. The crystallization of the samples is disappeared by increasing of neutron irradiation. In the Mossbauer spectrum of the sample, the lattice sites are three types. Two sites of them are ferromagnetic and the other one is paramagnetic. The Mossbauer parameters of the paramagnetic site are predominatly changed than the others.

망상형 정신분열증 환자의 지적 능력에 대한 고찰 : K-WAIS를 중심으로 based on K-WAIS

이귀행,오기모,한평주 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2

The authors surveyed 42 paranoid types, 38 undifferentiated types of schizophrenia and 47 neurosis by the K-WAIS to evaluate the intelligence state of the paranoid type of schizophrenia. The results were as follows. 1. Information scale made significant difference between the neuroses and the paranoid types of schizophrenic patients (P<0.1). 2. There were significant differences between the neurotic patients and the schizophrenic patients on all the scores of K-WAIS except information scale(P<0.05). 3. No differences were found between the paranoid and the undifferentiated types of the schizophrenic patients on the intelligence. 4. The paranoid types of schizophrenic patients showed significant difference between the verbal and the performance scale(P<0.1) According to above results, there was the difference of intelligent ability between the schizophrenic patients and the neuroses patients but not between the paranoid types and the undifferentiated types of schizophrenic patients.

N-Isoprophyliminotriphenylphosphorane과 Benzaldehyde 유도체와 반응

李英行,李晩求,金基炫 圓光大學校 基礎自然科學硏究所 1986 基礎科學硏究誌 Vol.5 No.2

The reactions of N- sopropyliminotriphenylphosphorane with benzaldehyde derivatives were investigated by GC. The reaction were completed within 8hours at an approximate reaction condition. The reactivity of benzaldehyde was in order, Ar=p-NO_2>p-Cl>p-Br>H>p-CH_3>p-CH_3O> and Ar=p-C_2H_5O, consistant with the Wittig mechanism. The reactivity of iminophosphorane increased with the change of reaction solvent from benzene to ethanol.

英語補文 構造에 관한 硏究

李基幸 朝鮮大學校 敎育大學院 1986 敎育論叢 Vol.2 No.2

견인골 신장술을 이용한 안모 비대칭 환자 치험례

태기출,강경화,이수행,유석근 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.5

견인골 신장술은 막내골화를 유도하는 조직 공학으로, 두개안면기형영역에서 치료는 지난 10년간 지속되었다. 본 연구는 하악지를 절단한 후 구강내 견인장치를 사용하여 안모 비대칭을 치료한 증례이다. 안모 비대칭 환자를 치료하는데 섬세하게 견인골 신장술을 이용하면 성장기와 성장이 끝난 환자에게서 효율적인 치료방법으로 생각된다. Distraction osteogenesis is a well estabilished procedure of membraneous hone formation and has been used to correct craniofacial deformities in dentofacial orthopedic surgery area for decades. In this article, distraction osteogenesis is used for treatment of facial asymmetry. The patient underwent procedures to lengthen the mandibular ramus and body. After distraction, orthodontic treatment was done for occlusal settling.

정신분열병의 적응상태에 따른 임상 특징 및 지능

오기모,이귀행 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.3

본 연구는 정신분열병 환자의 적응 상태에 따른 임상적 특성 및 지능을 알아보고자 하였다. 1993년 1월부터 1996년 11월까지 원광대학교 의과대학 부속병원 신경정신과에 입원한 정신분열병 환자중 139명이 선택되었다. 선택된 환자들은 두 집단으로 나누어졌다. 지난해 최고 수준의 전반적 기능 평가 척도(Past Year Highest Global Assessment of Functioning : PHF)를 60을 기준으로 60을 초과한 군을 상위군으로 60이하인 군을 하위군으로 하였다. 두 군의 임상적 특징과 K-WAIS 검사 결과를 비교하여 다음과 같은 결과를 얻었다. 1) 상위군이 교육기간 (11.9±2.99, 9.9±3.7, p〈.01)이 길고, 유병기간(49.6±57.9, 93.9±70.3, p〈.01)이 짧고, 입원횟수(1.9±1.3, 2.8±2.1, p〈.01)가 적고, 음성증상의 수(3.2±1.4, 3.8±1.3, p〈.01)가 적었다. 2) 상위군이 언어성 지능(90.5±14.5, 82.4±17.4, p〈.01), 동작성 지능 (81.4±13.5, 73.2±14.2, p〈.01), 전체지능(86.2±13.3, 78.0±14.9, p〈.01), 어휘 문제(9.2±3.0, 7.6±3.6, p〈.01), 이해문제(9.2±3.1, 7.5±3.4, p〈.01), 공통성 문제(8.6±2.6, 7.4±3.3, p〈.01), 바꿔쓰기(8.3±1.8, 7.3±2.5, p〈.01), 모양 맞추기(7.6±2.5, 6.6±2.3, p〈.01), 토막 짜기(7.9±2.6, 6.8±2.0, ,p〈.01), 빠진 곳 찾기(7.9±2.2, 7.0±2.1, p〈.01)의 점수가 유의하게 높았다. 이상의 결과를 종합하여 볼 때 정신분열병 환자에서 적응 상태가 좋은 상위군은 교육 기간이 길고, 유병기간이 짧고, 입원 횟수가 적고, 음성 증상의 수가 적었고, 언어성 지능, 동작성 지능, 전체 지능에서 더 높은 점수를 보였다. 상위군이 언어성 기능에서는 보다 복합적인 기능이, 동작성 지능에서는 공간 관리 능력이 하위군 보다 더 높은 것 같다. We investigated the clinical characteristics and intelligence in the adjustment of schizophrenic patients. One hundred thirty-nine schizophrenic patients were selected among the schizophrenic patients admitted to department of neuropsychiatric, Wonkwang University, school of medicine, from January 1, 1993 to November 30, 1996. The selected schizophrenic patients were divided into two groups, the one with over 60 of past year highest global assessment of functioning(PHF)(superior group) and the other with less than 60 of PHF(inferior group). Both groups were compared in clinical characteristics and Korean-Wechsler Adult Intelligence Scale(K-WAIS) results at admission. The results were as follows : 1) The superior group showed significantly longer duration of education(11.9±2.99, 9.9±3.7, p〈.01), shorter duration of illness(49.6±57.9, 93.9±70.3, p〈.01), less admissions(1.9±1.3, 2.8±2.1, p〈.01), less negative symptoms(3.2±1.4, 3.8±1.3, p〈.01) than the inferior group. 2) The superior group showed significantly higher scores on verbal intelligence quotient(VIQ : 90.5±14.5, 82.4±17.4, p〈.01), performance intelligence quotient(PIQ : 81.4±13.5, 73.2±14.2, p〈.01), full scale intelligence quotient(FSIQ : 86.2±13.3, 78.0±14.9, p〈.01), the subtests of vocabulary(9.2±3.0, 7.6±3.6, p〈.01), comprehension(9.2±3.1, 7.5±3.4, p〈.01), similarity(8.6±2.6, 7.4±3.3, p〈.05), digit symbol(8.3±1.8, 7.3±2.5, p〈.01), object assembly(7.6±2.5, 6.6±2.3, p〈.05), block design(7.9±2.6, 6.8±2.0, p〈.05), and picture completion(7.9±2.2, 7.0±2.1, p〈.05) than the inferior group. Finally, the patients with better adjustment showed higher education level, shorter duration of illness, less numbers of admission, less negative symptoms, and higher scores on VIQ, PIQ, FSIQ, and subtests of vocabulary, comprehension, similarity, digit symbol, object assembly, block design, picture completion. It seems that the superior group had better at the more complex function in the verbal intelligence and the ability of space in the performance intelligence than the inferior group.

새로운 축합시약을 이용한 아미드 합성법

鄭起源,蔡奎允,李英行 圓光大學校 1993 論文集 Vol.27 No.2

새로운 축합시약인 (3-nitropyridyl) dialkyl phosphate (3a,3b)를 2-hydroxy-3-nitropyridine (1), dialkyl chlorophosphate (2a,2b) 그리고 triethylamine을 dichloromethane 용액중에서 1시간동안 상온에서 반응시켜 쉽게 얻을 수 있었다. 축합시약인 3a와 3b는 온화한 반응 조건에서 아미드와 디펩티드를 합성하는데 있어서 유용한 시약임을 알 수 있었다. A new coupling reagents,(3-nitropyridyl) diallkyl phosphate (3a,3b), were readily prepared by the reaction of 2-hydroxy-3-nitropyridine (1), dialkyl chlorophosphate (2a,2b), and triethylamine in dichloromethane at room temperature for 1h. The coupling reagents, 3a and 3b, were found to be very useful for the preparation of amides and dipeptides under mild conditions.

자궁경부암 병기판정 기초검사시 새로운 보조방법으로서 고주파 질식 초음파의 가치

유희석,이은주,장기홍,권혁찬,양정인,김행수,오기석 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

To investigate the efficacy of endoluminal ultrasound system (EUS) as a surrogate for high frequency transvaginal ultrasonography and as an optional baseline study in determining parameirial and stromal invasion of early stage cervical cancer, 52 women suspected of cervical cancer underwent EUS. A 12 MHz endoscopic probe was employed to radially scan the cervix for possible lesions suspected to be invasive cancer during a period of 6 months from Feb. 1 to July 1, 1995. Patients also underwent magnetic resonance imaging (MRI) and/or computerized tomography (CT) as a routine mode of baseline study, and were clinically staged by 3 independent physicians specializing in Obstetrics and Gynecology at the Department of Obstetrics and Gynecology, School of Medicine, Ajou University, Suwon, Korea. Thirty one patients subsequently received surgery appropriate for the stage of the disease and the final pathology findings were compared with the results of clinical staging, EUS, MRI/CT by regression analysis. The results showed that there was statistically significant correlation between MRI/CT and pathology (r=0.660, p<0.02), between EUS and pathology (r=0.803, p<0.01), and between clinical staging and pathology (r=0.825, p<0.01). It is concluded that there was significant statistical correlation t>etween EUS, MRI/CT, clinical staging and pathology, but the question remained as to the statistical superiority of EUS over MRI/CT with regard to parametrial invasion and stromal invasion depth assessment. Finally, EUS is useful as an alternative optional diagnostic tool in the baseline study of cervical cancer.

Peptide Synthetase의 활성 Adenylate 형성 Domain의 발현

김연옥,김기영,이성,이영행,유병수 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1

본 연구에서는 typrocidine synthetase 1(tycA)를 motif-I에서 motif-O까지 결실시킨후 E. coli에 발현시켜 효소의 activity를 측정한 결과 motif-I에서 motif-O까지는 aminoadenylate 형성 과정에서 필수적인 부위가 아님을 규명하였다. 이 결과는 in vitro 실험을 통해 발표된 효소의 AMP binding(C-motif) Adenine binding(E-motif) 및 ATP binding(F-motif) 대한 연구를 뒷바침 할 수 있는 좋은 결과로 사료되고 있다. 위와같은 연구들을 통해 생체활성물질을 생성하는 multienzyme을 보다 더 잘 이해할 수 있으며 또한 이 합성효소들을 유전자 조작에 의한 새로운 효소 디자인 및 설계에 유용한 자료가 될 것이고, 아울러 위의 방법들을 응용할 경우 신물질을 개발할 수 있는 하나의 좋은 방법이 될 것이다. The plasmid pK8 was constructed to verify the existence of an adenylate domain in peptide synthetase by using pGC12. 1.2 kb fragment, coding typrocidine synthetase 1 (123 kDa) was deleted, and 79.6 kDa one was expressed in Escherichia coli XL1-blue. The truncated multienzyme activated phenylalanine and substrate analogues with comparable kinetics as the over expressed synthetase. ATP-[^32]PPi exchange reaction was measured for the enzyme assay.

보리순의 영양성분 조성

서혜지,최용민,김상천,이준수,이기택,정명근,천지연,황진봉,남진식,서우덕,황영,김행란,김세나 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2