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Lee, Gil-Yong,Ha, Suk-Jin,Jung, Jong-Hyun,Seo, Dong-Ho,Park, Jong-Yul,Kim, Su-Rin,Park, Nam-Woo,Kweon, Dong-Keon,Park, Sang-Hoo,Park, Cheon-Seok The Korean Society for Applied Biological Chemistr 2009 Applied Biological Chemistry (Appl Biol Chem) Vol.52 No.3
Hyaluronic acid (HA) is a linear high-molecular-weight polysaccharide with useful biomedical applications. Streptococcus zooepidemicus, a typical HA-producing bacterium, requires an animal-derived nitrogen source such as tryptone, peptone or sheep blood as a nutrient. Sixteen non-animal-derived (NAD) nitrogen sources were tested as a replacement for the expensive animal-derived nitrogen sources, which may have safety issues. Among the sixteen tested NAD nitrogen sources, a yeast-derived nitrogen source (YE 0251) showed the highest HA productivity, which was equivalent to the control HA production medium containing tryptone in a 5-L jar and in 3,000-L industrial fermentations. In the 3,000-L fermentation, YE 0251 increased cell mass (dry cell weight) and HA production by 11% and 8%, respectively, compared with the control HA production medium. The fmal specific volumetric productivity (0.41 g/L h) was improved by about 70% after reducing the fermentation time from 20 h to 12 h, compared to the conventional production medium.
부산 일부 대학교 학생들의 니코틴 의존도와 구취의 연관성
김유린(외 5명) 신라대학교 자연과학연구소 2012 自然科學論文集 Vol.22 No.-
The purpose of this study is to examine the association of bad breath and nicotine dependency. By use of the findings from this study, This study conducted the survey of 53 smoker who visited dental hygiene lab for delivery from October to November 2012 with structured questionnaires(Fagerstrom Tolerance Questionnaire FTQ) and equipment(CO measuring instrument, Oral Chroma etc). The data were analyzed by using SPSS 20.0 program for χ2-test, ANOVA. Smokers' average age was 23 years old. The more higher nicotine dependence the more the average age was higher. The more higher nicotine dependence the less to nque brushing. No association of nicotine dependence and self-bad breath level. CO State was Significant differences(ND1(M=2.58), ND2(M=3.98), ND3(M=7.41), ND4(M=4.19), ND5(M=13.14))(F=2.616, p=.047). Dimethyl Sulfide was Significant differences(F=3.026, p=.026).
Antioxidant activity of hot water extract from Hydrallgea macrophylla var. thunbergii
Ha Rin Park,Ju Eun Kim,Su Ji Park,Ha Yeon Park,Eun Seo Beak,Myo Jeong Kim 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
The aim of this study is to evaluate antioxidant activities of Hydrallgea macrophylla var. thunbergii(Sookuk tea) extracts. Hot water extract of Sookuk tea leave was fractionated serially by n-hexane, chloroform, ethyl acetate, and n-butanol. The antioxidant activity of each fraction was tested using a DPPH method. The IC50 value for scavenging 50% DPPH radicals was 2.50±0.04 mg/mL for hot water extract of Sookuk tea leave. Among the fractions, the IC50 value of ethyl acetate fraction was the lowest (0.461±0.004 mg/mL) and the residual aqueous fraction was the highest (6.30±0.30 mg/mL). The total polyphenol and flavonoid content of the ethyl acetate fraction were the highest, which supported the strong antioxidant activity of the fraction.
ADAM29 Elevation in Patients with COPD and Its Association with Lung Function
( Shinhee Park ),( Min Hyeok An ),( Pureun-haneul Lee ),( Yun Ha Nam ),( Ae Rin Baek ),( Jong Sook Park ),( Junehyuk Lee ),( Sung-woo Park ),( Do Jin Kim ),( An Soo Jang ) 대한결핵 및 호흡기학회 2023 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.136 No.0
Ha-Na Park,Jeong-Yee Han,Hae-Rin Yoon,Soo-Yeon Jeong,Doo-Ran Kim,Kwang-Ho Lee 한국교원대학교 뇌기반교육연구소 2017 Brain, Digital, & Learning Vol.7 No.1
The purpose of this study was to examine and analyze the cognitive demand of the mathematical tasks suggested in the elementary school textbooks in Korea and Japan. In particular, it aimed to reveal the overall picture of the level of cognitive demand of the mathematical tasks in the strand of proportional reasoning in the textbooks. We adopted the framework for mathematical task analysis suggested by Stein & Smith(1998) and analyzed the mathematical tasks accordingly. The findings from the analysis showed that 38.9 percent of the mathematical tasks were at high level and the rest at low level in terms of cognitive demand in Korea. In Japan 18.7 percent of the mathematical tasks were at high level and the rest at low level in terms of cognitive demand. Most of the mathematical tasks in the textbooks were algorithmic and focused on producing correct answers by using procedures in both countries.
LC : Evaluation of Adrenal Insufficiency in Cirrhotic Patients in Korea
( Ha Na Yoo ),( Su Rin Shin ),( In Ho Moh ),( Sang Hoon Park ),( Myung Seok Lee ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background: Adrenal insufficiency (AI) is frequent in cirrhotic patients with severe infection or hemodynamic instability. However, there is limited data about the prevalence of AI in stable cirrhotic patients and the impact of etiology of cirrhosis on AI. This study prospectively evaluated prevalence and characteristic of AI in stable cirrhotic using the conventional short synacthen, a synthetic analogue of adrenocorticotrophic hormone. Methods: From July 2011 to Aug 2012, a total of 50 cirrhotic patients without infections or hemodynamic instability admitted to two university-affi liated hospitals were enrolled. AI was defined by a total serum cortisol level < 18 μg/dL at 30 or 60 min after injection of 250 μg of synacthen. Results: Thirty eight patients were men and age was ranged 29-89 years. Etiology of cirrhosis was alcohol/viral hepatitis/ both/others in 26/6/10/8 patients. AI was present in 18 patients (36%). No significant difference was observed regarding age, gender, mean arterial pressures, and heart rates between patients with and without AI. The etiology of cirrhosis and degree of alcohol consumption did not affect presence of AI or basal and peak serum cortisol levels either. Prothrombin time was higher, while albumin was lower in patients with AI than those without AI. However, in multivariate analysis, there was no independent predictor of AI. The prevalence of AI increased according to severity of liver disease (17, 50, and 33% in Child- Pugh class A, B, and C respectively; P=0.174). There were negative correlations between Child-Pugh score and both basal cortisol (γ=-.377, P=0.007) and peak cortisol levels (γ=-.373, P<0.005) Conclusions: In this study, AI was frequent in stable cirrhotic patients without infections or hemodynamic instability. AI was not related to the etiology of cirrhosis or alcohol consumption, either. AI tended to be associated with only severity of liver disease.