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하악골 골절 치료를 위한 miniplate와 관련된 매복견치의 치험례
황상희,박효상,권대근,남기영,김종배 대한치과교정학회 2005 대한치과교정학회지 Vol.35 No.2
하악 좌측 견치의 미맹출을 주소로 내원한 10세 여환의 과거 병력 조사 중 3년 전 교통사고로 하악 좌측 골체부에 골절이 생겨 miniplate로 관혈적 정복술을 시행받은 것을 발견하였다. 통상적인 외과적 노출과 교정적 견인치료로는 견치 맹출에 실패하였고, miniplate를 제거함으로써 정상적인 매복 견치 맹출에 성공하였기에 보고하는 바이다. This case report describes the treatment of an impacted tooth in relation to pediatrlc mandibular fracture. A 10-year-old girl presented with an impacted mandibular canine related with a miniplate in the left mandibular body area. An ordinary surgical traction ended in failure. Good occlusion was established by removal of the miniplate. It would be considered important to make an exact diagnosis of the cause and remove the mechanical obstruction instantly for successful orthodontlc treatment of an impacted tooth.
Hwang, Geon-Tae,Palneedi, Haribabu,Jung, Byung Mun,Kwon, Suk Jin,Peddigari, Mahesh,Min, Yuho,Kim, Jong-Woo,Ahn, Cheol-Woo,Choi, Jong-Jin,Hahn, Byung-Dong,Choi, Joon-Hwan,Yoon, Woon-Ha,Park, Dong-Soo,L American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.38
<P>We report the effect of epoxy adhesion layers with different mechanical or physical property on a magnetoelectric (ME) composite laminate composed of FeBSi alloy (Metglas)/single-crystal Pb(Mg<SUB>1/3</SUB>Nb<SUB>2/3</SUB>)O<SUB>3</SUB>-Pb(Zr,Ti)O<SUB>3</SUB>/Metglas to achieve an improved ME conversion performance. Through theoretical simulation, it was revealed that the Young’s modulus and the thickness of interfacial adhesives were major parameters that influence the conversion efficiency in ME composites. In the experimental evaluation, we utilized three epoxy materials with a distinct Young’s modulus and adjusted the average thickness of the adhesion layers to optimize the ME conversion. The experimental results show that a thin epoxy layer with a high Young’s modulus provided the best performance in the inorganic-based ME conversion process. By tailoring the interfacial adhesion property, the ME laminate generated a high conversion coefficient of 328.8 V/(cm Oe), with a mechanical quality factor of 132.0 at the resonance mode. Moreover, we demonstrated a highly sensitive alternating current magnetic field sensor that had a detection resolution below 10 pT. The optimization of the epoxy layers in the ME laminate composite provided significant enhancement of the ME response in a simple manner.</P> [FIG OMISSION]</BR>
Sequential Treatment with SDF-1 and BMP-2 Potentiates Bone Formation in Calvarial Defects
Hwang, Hee-Don,Lee, Jung-Tae,Koh, Jeong-Tae,Jung, Hong-Moon,Lee, Heon-Jin,Kwon, Tae-Geon Mary Ann Liebert 2015 Tissue engineering. Part A Vol.21 No.13
<P>Stromal cell-derived factor-1 (SDF-1) protein and its receptor, CXCR-4, play an important role in tissue repair and regeneration in various organs, including the bone. SDF-1 is indispensable for bone morphogenetic protein-2 (BMP-2)-induced osteogenic differentiation. However, SDF-1 is not needed after the osteogenic induction has been activated. Since the precise condition for the additive effects of combined DF-1 and BMP-2 in bone healing had not been fully investigated, we aimed to determine the optimal conditions for SDF-1- and BMP-2-mediated bone regeneration. We examined the in vitro osteoblastic differentiation and cell migration after sequential treatments with SDF-1 and BMP-2. Based on the in vitro additive effects of SDF-1 and BMP-2, the critical size defects of mice calvaria were treated with these cytokines in various sequences. Phosphate buffered saline (PBS)-, SDF-1-, or BMP-2-soaked collagen scaffolds were implanted into the calvarial defects (n=36). Periodic percutaneous injections of PBS or the cytokine SDF-1 and BMP-2 into the implanted scaffolds were performed on days 3 and 6, postoperatively. Six experimental groups were used according to the types and sequences of the cytokine treatments. After 28 days, the mice were euthanized and bone formation was evaluated with microcomputed tomography and histology. The molecular mechanism of the additive effect of SDF-1 and BMP-2 was evaluated by analyzing intracellular signal transduction through Smad and Erk phosphorylation. The in vitro experiments revealed that, among all the treatments, the treatment with BMP-2 after SDF-1 showed the strongest osteoblastic differentiation and enhanced cell migration. Similarly, in the animal model, the treatment with SDF-1 followed by BMP-2 treatment showed the highest degree of new bone regeneration than any other groups, including the one with continuous BMP-2 treatment. This new bone formation can be partially explained by the activation of Smad and Erk pathways and enhanced cell migration. These results suggest that sequential treatment with the cytokines, SDF-1 and BMP-2, may be a promising strategy for accelerating bone regeneration in critical size defects.</P>
Hwang, Geon-Tae,Im, Donggu,Lee, Sung Eun,Lee, Jooseok,Koo, Min,Park, So Young,Kim, Seungjun,Yang, Kyounghoon,Kim, Sung June,Lee, Kwyro,Lee, Keon Jae American Chemical Society 2013 ACS NANO Vol.7 No.5
<P>Biointegrated electronics have been investigated for various healthcare applications which can introduce biomedical systems into the human body. Silicon-based semiconductors perform significant roles of nerve stimulation, signal analysis, and wireless communication in implantable electronics. However, the current large-scale integration (LSI) chips have limitations in <I>in vivo</I> devices due to their rigid and bulky properties. This paper describes <I>in vivo</I> ultrathin silicon-based liquid crystal polymer (LCP) monolithically encapsulated flexible radio frequency integrated circuits (RFICs) for medical wireless communication. The mechanical stability of the LCP encapsulation is supported by finite element analysis simulation. <I>In vivo</I> electrical reliability and bioaffinity of the LCP monoencapsulated RFIC devices are confirmed in rats. <I>In vitro</I> accelerated soak tests are performed with Arrhenius method to estimate the lifetime of LCP monoencapsulated RFICs in a live body. The work could provide an approach to flexible LSI in biointegrated electronics such as an artificial retina and wireless body sensor networks.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-5/nn401246y/production/images/medium/nn-2013-01246y_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn401246y'>ACS Electronic Supporting Info</A></P>
Self-powered deep brain stimulation via a flexible PIMNT energy harvester
Hwang, Geon-Tae,Kim, Youngsoo,Lee, Jeong-Ho,Oh, SeKwon,Jeong, Chang Kyu,Park, Dae Yong,Ryu, Jungho,Kwon, HyukSang,Lee, Sang-Goo,Joung, Boyoung,Kim, Daesoo,Lee, Keon Jae The Royal Society of Chemistry 2015 ENERGY AND ENVIRONMENTAL SCIENCE Vol.8 No.9
<P>Deep brain stimulation (DBS) is widely used for neural prosthetics and brain-computer interfacing. Thus far <I>in vivo</I> implantation of a battery has been a prerequisite to supply the necessary power. Although flexible energy harvesters have recently emerged as alternatives to batteries, they generate insufficient energy for operating brain stimulation. Herein, we report a high performance flexible piezoelectric energy harvester by enabling self-powered DBS in mice. This device adopts an indium modified crystalline Pb(In1/2Nb1/2)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 (PIMNT) thin film on a plastic substrate to transform tiny mechanical motions to electricity. With slight bending, it generates an extremely high current reaching 0.57 mA, which satisfies the high threshold current for real-time DBS of the motor cortex and thereby could efficiently induce forearm movements in mice. The PIMNT based flexible energy harvester could open a new avenue for future <I>in vivo</I> healthcare technology using self-powered biomedical devices.</P>
A Reconfigurable Rectified Flexible Energy Harvester via Solid-State Single Crystal Grown PMN-PZT
Hwang, Geon-Tae,Yang, Joonseok,Yang, Seong Ho,Lee, Ho-Yong,Lee, Minbok,Park, Dae Yong,Han, Jae Hyun,Lee, Seung Jun,Jeong, Chang Kyu,Kim, Jaeha,Park, Kwi-Il,Lee, Keon Jae Wiley Blackwell (John Wiley Sons) 2015 ADVANCED ENERGY MATERIALS Vol.5 No.10
자기-전기(ME) 복합체를 활용한 초미세 자기장 감지 기술
황건태(Geon-Tae Hwang),송현석(Hyunseok Song),장종문(, Jongmoon Jang),류정호(Jungho Ryu),윤운하(Woon-Ha Yoon) 한국세라믹학회 2020 세라미스트 Vol.23 No.1
Magnetoelectric (ME) composites composed of magnetostrictive and piezoelectric materials derive interfacial coupling of magnetoelectric conversion between magnetic and electric properties, thus enabling to detect ultra-low magnetic field. To improve the performance of ME composite sensors, various research teams have explored adopting highly efficient magnetostrictive and piezoelectric phases, tailoring of device geometry/ structure, and developing signal process technique. As a result, latest ME composites have achieved not only outstanding ME conversion coefficient but also sensing of ultra-low magnetic field below 1pT. This article reviews the recent research trend of ME composites for sensing of ultra-low magnetic field.
황건태(Geon-Tae Hwang),류정호(Jungho Ryu),윤운하(Woon-Ha Yoon) 한국세라믹학회 2021 세라미스트 Vol.24 No.3
Magneto-mechano-electric (MME) conversion composites composed of distinctive magnetostrictive and piezoelectric materials derive interfacial coupling of magnetoelectric conversion between magnetic and electric properties, thus enabling energy harvesting and magnetic sensing. To demonstrate highperformance MME composites and their applications, various research teams have studied tailoring device structures, enhancing material properties, and developing MME application system. This article reviews the recent research progress of MME composites for energy harvesting and magnetic sensing.
Development of a new forage winter oat cultivar for the mid-southern region of Korea
Ouk-Kyu Han,Tae-Il Park,Hyong-Ho Park,Tae-Hwa Song,Kee-Jong Kim,Jong-Jin Hwang,Seong-Bum Baek,Dea-Wook Kim,Jung-Il Ju,Young-Jik Jang,Nam-Geon Park,Young-Up Kwon 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07
’Dahan’ (Avena sativa L.), a winter oat for forage use, was developed by the breeding team at the Department of Rice and Winter Cereal Crop, National Institute of Crop Science (NICS), RDA in 2011. It was derived from an original cross between the F1 hybrid of ‘Sprinter’ and ‘73625’ and ‘Gwiri26’ (PA7507-37). Subsequent generations followed by the cross were handled in bulk and pedigree selection programs at Suwon. A line, ‘SO99027-GB-B-113-4-4-3’, was selected for cold tolerance and good agronomic characteristics and designated as a line name of ‘Gwiri75’. The line ‘Gwiri75’ was subsequently evaluated for cold tolerance, earliness, and forage yield in four different locations, Yesan, Iksan, Kimjae, and Jeju, from 2009 to 2011 and finally named as ‘Dahan’. Over 3 years, the average forage dry matter yield of ‘Dahan’ harvested at milk-ripe stage was 15.6 MT ha-1, compared with 14.1 MT ha-1 of check cultivar ‘Samhan’. Though similar in heading date to the check cultivar, ‘Dahan’ had tall plant length and lodging resistance. The feed value of ‘Dahan’ was superior to the check cultivar in percent total digestible nutrients (TDN) and TDN yield per ha. ‘Dahan’ is recommended primarily for winter planting use in the areas where daily minimum mean temperatures are averaged higher than -6 ℃ in January, and excluded in mountain area where frost damage is presumable.