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운동 직후 고온 침수가 EPOC와 TG/ fatty acid cycling에 미치는 영향
조현철,김종규,강민철,홍완표,박노혁 龍仁大學校 體育科學硏究所 2005 體育科學硏究論叢 Vol.15 No.1
The purpose this study was to estimate effects of EPOC and TG/fatty acid cycling on warm water immersion of immediately after exercise. To elucidate the role of fatty metabolism, a sequence of five experiments was performed. Seven physically active, male subjects volunteered to participate in the presented study. The mean values for age, body mass and hight were 25±1.52 yr, 79.2±9.52kg, 177.2±4.62cm, respectively. After giving consent, participant visited the laboratory on six occasion: 1) 30min of treadmill exercise VO2max 55% and a further 60min recovery, 2) 30min partial body warm water immersion in a 39℃ and a further 60min recovery, 3) 30min whole body warm water immersion in a 39℃ and a further 60min recovery, 4) 30min of treadmill exercise VO2mas 55% and in 30min partial body warm water immersion in a 39℃, 5) 30min of treadmill exercise VO2max 55% and in 30min whole body warm water immersion in a 39℃. When compared by recover period within repeat on the base of changes of subjects average body temperature, not effective interactions among repeat. However, partial and whole body warm water immersion immediately after exercise shows it as the best effective exercise for VO2max 55%, partial and whole body warm water immersion. When compared by recover period within repeat on the base of changes of subjects EPOC, effective interactions among repeat(p<.05). Partial and whole body warm water immersion immediately after exercise shows it as the best effective exercise for VO2mas 55%, partial and whole body warm water immersion. The catecholamines concentration was significantly higher partial and whole body warm water immersion than exercise of VO2max 55%(p<.05). The TG concentration and free fatty acid was significantly higher partial and whole body warm water immersion immediately after exercise than exercise of VO2max 55% than Partial and whole body warm water immersion(p<.05). Based on the facts that we have discussed above, human metabolism is increased by both exercise and conditions of immersion and partial and whole body warm water immersion immediately after exercise than exercise of VO2maw 55% shows it as better effective treatment for increasing TG/Fatty acid cycling activation. Due to extremely heavy stress complained by subjects during whole body immersion, it is thought that more researches on it should be required.
Chul Kyu Roh,Sang-Uk Han 대한내시경복강경외과학회 2020 Journal of Minimally Invasive Surgery Vol.23 No.1
The recent advancements in surgical techniques and perioperative care have improved postoperative morbidity and survival after gastric cancer surgeries. However, anastomotic leakage, the most serious complication post-gastrectomy, continues to occur. In esophageal and colorectal cancer surgeries, the omentum is used as a physical barrier and increases blood perfusion to prevent leakage to the anastomotic site. However, the use of the omentum as an anastomotic barrier after gastrectomy has not been reported yet. The authors aimed to evaluate the efficacy and safety of omental free-shaped flap reinforcement on the anastomosis and dissected area following reconstruction after gastrectomy for preventing and treating anastomotic leakage. They reported that omental free-shaped flap reinforcement on the anastomosis might prevent anastomotic leakage post-gastrectomy. The omental flap also prevented further deterioration when leakage occurred. However, anastomosis-related complications, such as anastomotic stenosis and delayed gastric emptying, after an omental patch technique need to be evaluated further.
Chul Kyu Roh,이수민,손상용,허훈,한상욱 대한위암학회 2021 Journal of gastric cancer Vol.21 No.4
Purpose: Minimally invasive gastrectomy is a promising surgical method with well-known benefits, including reduced postoperative complications. However, for total gastrectomy of gastric cancers, this approach does not significantly reduce the risk of complications. Therefore, we aimed to evaluate the incidence and risk factors for the severity of complications associated with minimally invasive total gastrectomy for gastric cancer. Materials and Methods: The study included 392 consecutive patients with gastric cancer who underwent either laparoscopic or robotic total gastrectomy between 2011 and 2019. Clinicopathological and operative characteristics were assessed to determine the features related to postoperative complications after minimally invasive total gastrectomy. Binomial and multinomial logistic regression models were used to identify the risk factors for overall complications and mild and severe complications, respectively. Results: Of 103 (26.3%) patients experiencing complications, 66 (16.8%) and 37 (9.4%) developed mild and severe complications, respectively. On multivariate multinomial regression analysis, independent predictors of severe complications included obesity (OR, 2.56; 95% CI, 1.02−6.43; P=0.046), advanced stage (OR, 2.90; 95% CI, 1.13−7.43; P=0.026), and more intraoperative bleeding (OR, 1.04; 95% CI, 1.02−1.06; P=0.001). Operation time was the only independent risk factor for mild complications (OR, 1.06; 95% CI, 1.001−1.13; P=0.047). Conclusions: The risk factors for mild and severe complications were associated with surgery, indicating surgical difficulty. Surgeons should be aware of these potential risks that are related to the severity of complications so as to reduce surgery-related complications after minimally invasive total gastrectomy for gastric cancer.
저온·알칼리성 Protease를 생산하는 Pseudomonas sp. RP-222의 분리 및 조효소의 특성
노종수,정영철,박석규,성낙계 한국산업미생물학회 1991 한국미생물·생명공학회지 Vol.19 No.4
저온에서 높은 활성을 나타내는 알칼리성 protease를 생산하기 위하여 여러가지 시료로부터 집적배양에 의해 저온성 세균을 분리하였다. 분리된 세균은 저온·저알칼리성 Pseudomonas sp.인 것으로 판명되었으며, 효소생산을 위한 균생육의 최적 pH는 10.0, 온도 20℃에서 4일간 배양하였을 때였다. 이 효소활성의 최적 pH 및 온도는 각각 pH 10.5 및 40℃였으며, pH 및 열안정성은 각각 pH 7.0∼13.0, 온도 50℃ 이하의 범위에서 비교적 안정하였다. 또한 이 효소는 PMSF와 EDTA에 의해서 저해되므로 활성부위에 serine기와 금속이온이 관여하는 것으로 추정되며 계면활성제의 존재하에서도 안정하였다. 효소의 활성은 0.05% Na-α-olefin sulfonate 첨가에 의해 약간 증가되었다. In order to produce alkaline protease, psychrotrophic bacterium which have high enzyme activity at low temperature, was isolated by using enrichment culture from various samples and identified as genus alkalopsychrotropic Pseudomonas sp. RP-222. The optimal culture conditions for enzyme production were pH-10.0, temperature-20℃ and culture time-4 days. The optimum pH and temperature for the enzyme activity were pH 10.5 and 40℃, respectively and the enzyme was relatively stable at pH 7.0∼13.0 and below 50℃. The emzyme was inhibited by ethylenediaminetetraacetate and phenylmethylsulfonylfluoride, indicating that the enzyme was a serine metalloenzyme, but considerably stable in the presence of surface active agents. Activity of the enzyme was increased by the addition of 0.05% Na-α-olefin sulfonate.
노성우,정상섭,박용구,임승철,이규창 대한신경외과학회 1987 Journal of Korean neurosurgical society Vol.16 No.4
To preserve function of the acoustic nerve and brainstem during posterior fossa surgery, the authors monitored (brainstem auditory evoked potentials) in 42 cases of posterior fossa surgery who were operated at the Department of Neurosurgery of Yonsei University College of Medicine from March, 1983 to February, 1987. The results were summarized as followings : 1) There were 28 cases of hemifacial spasm, 13 cases of trigeminal neuralgia and 1 case of cerebello-pontine angel tumor. 2) Among the 41 cases of neurovascular decompression, there were 10 cases(24%) with hearing impairment postoperatively. But there was no postoperative auditory dysfunction in 13 cases of hemifacial spasm in which caudal approach was utilized. 3) There was no postoperative auditory dysfunction in the patients who showed intraoperative BAEPs of Types Ⅰ, Ⅱ and Ⅲ which were characterized by no loss of waves, but 10 cases(77%) who showed BAEPs of Types Ⅳ, Ⅴ and Ⅵ which were characterized by loss of the waves showed auditory dysfunction postoperatively.