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      • 변형된 MESI를 이용한 캐쉬 일관성 프로토콜

        최인석,조병호,심원 서울産業大學校 産業大學院 1997 大學院論文集 Vol.5 No.-

        This paper suggests a cache coherence protocol which improves the efficiency of MESI protocol. The suggested cache coherence protocol maintains 6 types of cache states and ID area. The cache states are divided into 3 valid (exclusive, modified, modified-shared, shared) and 2 invalid (invalid, invalid-by-other) states. ID area holds the identification of the processor module with valid block. We can decrease broadcasting and snooping by the suggested protocol. In addition to it, we can shorten the responce time through cache-to-cache communication. According to simulation results, We get around 2% efficiency improvement compared with MMESSII protocol which is a improved MESI protocol as the number of processors are increasing.

      • SCOPUSSCIEKCI등재

        뇌동맥류 파열 환자에서 증후성 뇌혈관연축의 발생 및 회복에 영향을 미치는 인자들

        최석민,석종식,권정택,민병국,황성남,김영백,홍현종 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.10

        To determine the factors affecting development and recovery of symptomatic vasospasm. the author analysed the results of patients with ruptured intracranial aneurysms treated by nimodipine and prophylactic “triple0H” therapy. From January 1991 to December 1995. 199 patients underwent surgery for ruptured intracerebral aneurysms. Combined hypervolemic hemodilution was initiated at the time of admission. Induced hypertension was added immediately after surgery(aneurysmal neck clipping). All patients received nimodipine intravenously or orally until the 14th day of SAH Sixty patients underwent surgery on Day 0 through 2 after attacks of subarachnoid hemorrhage(Goup A) 105 patients on Day 3 through 14(Group B). and 35 patients after Day 14(Group C). Of 199 patients. 76(38%) patients suffered from symtomatic vasospasm. Symptomatic vasospasm occured in 34% of Group A patients. 33% of Group B patients. and 5% of Group C patients. Symtomatic vasospasm occured more frequently in the older age group. the Fisher group 3 and Hunt & Hess grades 3, 4 and 5 groups. Of 76 patients who suffered from symptomatic vasospasm. 47(62%) patients recovered completely. The author analysed the relationship between recovery rate and sex, age. Hunt & Hess agrde and Fisher group among these 76 patients. Recovery rates between these groups were not significantly different. Based on this experience the author believes that Hunt-Hess grade. Fisher group and age are important factors affecting symptomatic vasospasm development.

      • 상처치유시 Antisense TGF-β1 Oligodeoxynucleotides가 Inducible Nitric Oxide Synthase발현 조절에 미치는 영향

        최병민,곽현정,전창덕,임정식,박석돈,정헌택 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.4

        Wound healing in the skin may be complicated by both microbial invasion and inflammation. Following injury, platelet degranulation releases a number of chemotactic factors including transforming growth factor (TGF-fl) and platelet derived growth factor (PDGF). TGF-19 is a cytokines that modulates many cellular function and gene expression. However, it is not known whether TGF-P could regulate inducible nitric oxide synthase (iNOS) gene expression during wound healing. Here we report that down regulation of TGF-Q gene expression by antisense oligodeoxynucleotides increase iNOS during wound healing. Our reverse transcription- polymerase chain reaction (RT-PCR) result has shown that antisense TGF-fil oligodeoxynucleotides (ODN) targeting the TGF-J11 translation initiation region markedly reduced TGF-(il mRNA levels in wounded skin. Also, marked reduction in TGF-fl1 mRNA after antisense treatment invited that the increment of iNOS mRNA in wounded skin. Therefore, our irnmunohistochemical studies revealed a "pattern of iNOS product in wounded skin treated antisense TGF-fl1 ODN that was similar to the pattern of RNA synthesis detected by RT-PCR. In conclusion, our results indicated that the regulatory actions of TGF fl1 on iNOS. might be involved in the initiation and faciliates the resolution of inflammation following wounding.

      • 한국산 닥나무류의 해부학적, 화학적 성질 및 펄프화 특성

        최태호,조남석,김병로 충북대학교 농업과학기술연구소 1991 農業科學硏究 Vol.9 No.2

        This study was carried out to investigate the papermaking characteristics for New Hanji (Korean Paper) products from paper mulberries. So far the bast fibers of paper mulberry species have been used as raw materials for Hanji. But, in this study, bast fibers, woody parts and whole woods are attempting for being utilize as new raw materials for special Hanji. Anatomical and chemical properties of 3 paper mulberry species and their pulping characteristics were discussed.

      • KCI등재

        한국 연안 퇴적물에서 ^137Cs, ^90Sr 및 Pu 동위원소의 분포

        최석원,진현국,김철수,노정환,김창규,노병환 대한방사선 방어학회 2002 방사선방어학회지 Vol.27 No.2

        한국 주변 연안 15개 정점의 퇴적물(0∼20 cm)에서 ^137Cs, ^90Sr, ^239+240Pu 의 농도와 농도비를 조사했다. ^137Cs, ^90Sr, ^238Pu 및^239+240Pu의 평균 방사능 농도는 각각 2.24±0.79 Bq·kg^-1-dry, 0.20±0.04 Bq·kg^-1-dry, 0.009±0.005 Bq·kg^-1-dry 및 0.27±0.17 Bq·kg^-1-dry이다. ^137Cs/^90Sr, ^239+240Pu/^137Cs 및 ^238Pu/229+240Pu의 평균 농도 비와 ^239Pu/240의 평균 원자 비는 각각 11.2±2.9, 0.123±0.053, 0.033±0.01 및 0.218±0.036이다. 퇴적물에서 핵종의 농도 범위와 핵종간의 농도 비는 그 동안 주변국가의 퇴적물에서 조사한 값과 비슷하였다. 퇴적물에서 ^137Cs과 ^239+240Pu의 상관계수는 0.80이다. ^137Cs과 SOM, ^239+240Pu과 점토 함량과의 상관계수는 각각 0.69, 0.67 이다. The concentrations and activity ratios of ^137Cs, ^90Sr, ^238Pu and ^239+240Pu in sediment(0∼20 cm) at 15 coastal stations of Korea were determined. The mean concentrations of ^137Cs, ^90Sr, ^238Pu and ^239+240Pu are 2.24±0.79 Bq·kg^-1-dry, 0.20±0.04 Bq·kg^-1-dry, 0.009±0.005 Bq·kg^-1-dry and 0.27±0.17 Bq·kg^-1-dry, respectively. The mean activity ratios of ^137Cs/^90Sr, ^239+240Pu/^137Cs and ^238Pu/^229+240Pu and atomic ratio of ^240Pu/^239Pu are 11.2±2.9, 0.123±0.053 and 0.033±0.017 and 0.218±0.036, respectively. The concentrations and activity ratios in sediment samples are similar to those reported from neighbouring country in the northern hemisphere. The correlation coefficient of ^137Cs and ^239+240Pu is 0.80. The correlation coefficient of ^137Cs and soil organic matter(SOM), and ^239+240Pu and clay content are 0.69 and 0.67, respectively.

      • KCI등재

        The Ameliorative Effects of Korean Bean‐Leaves on Inflammation and Liver Injury in Obese Rat Model

        Byung?Moon Jin,Seok?Cheol Choi,Hye?Sook Lee,Sang?Bong Jung,Kyung?Yae Hyun 대한의생명과학회 2013 Biomedical Science Letters Vol.19 No.3

        Obesity may cause metabolic syndrome and adult diseases. This study was undertaken to investigate the ameliorative or useful effects of beanleaves on inflammation and liver damage in obese rat models. Rats were divided into three groups: a control group (normal diet, n=6), a fat diet group (45%?fat diet, n=7), and a bean leaf group (45%?fat+Korean bean leaves diet, n=7). Body weights in the bean leaf group were lower than those of the fat group (P<0.05). Serum tumor necrosis factor?α (TNF?α) and prostaglandin E₂ (PGE₂) concentrations were lower in both the control and bean leaf groups than in the fat group (P<0.001). TNF?α concentrations in the bean leaf group were slightly higher than in the control group but statistically significant (P<0.05). The bean leaf group histologically exhibited lower fatty degeneration, spotty necrosis, and leukocyte infiltrations in hepatic tissues than those of the fat group. In the homogenized liver tissues, the cyclooxygenase?2 (COX?2) gene was only expressed in the fat group. The gene expression levels of hepatic TNF?α, inducible nitric?oxide synthase, peroxiome proliferator?activated receptor?α (PPAR?α), poly (ADP?ribose) polymerase (PARP), and transforming growth factor?β1 (TGF?β1) were weaker in the bean leaf group than in the fat group. These results suggest that adding bean?leaves to the diet may ameliorate obesity?induced systemic inflammation and liver damage and that bean leaves may be a useful food for preventing obesity and thereby metabolic syndrome and adult diseases

      • 바리온 OCTET의 첫째 여기상태에 대한 자기능률

        김석곤,최규현,김경훈,김병택 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.1

        현상학적인 Bag모델을 이용하여 바리온 octet의 첫째 여기상태에 대한 자기능률을 계산하였다. 바리온이 여기됐을 때 그 자기능률의 절대치는 바닥상태의 값보다 작아짐을 알 수 있었다. We calculated the magnetic moments of the first excited states of the baryon octet in the phenomenological bag model. It is found that the absolute values of magnetic moments are smaller than those of the ground states when the baryons are excited.

      • 반연속폭포 HMM을 이용한 한국어 지역명 인식

        조병서,최갑석,이용동 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

        This paper studies on the Korean word recognition using the semi-continuous hidden Markov model(SCHMM) which approximate the discrete hidden Markov model(DHMM) to the continuous hidden Markov models(CHMM). In generating of this model, the output probability of an input vector, which is assumed to the mixture continuous Gaussian distribution, is linearly combined with the probability function of each input vector and the symbol output of codewords for approximating to the CHMM, In the word recognition, this model recognized words more correctly than the DHMM because of reducing a quantized distortion due to the DHMM. In order to evaluate this model, comparing experiments between DHMM and SCHMM are carried out for DDD area names. Also, input vector takes the traditional LPC or the LPC cepstrum using euclidean distance. As a result, recognition rate of the SCHMM using the LPC cepstrum is improved.

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