도시 노숙자의 주요 정신장애에 관한 역학 연구

안준호,홍진표,유제춘,박종익,이철,한오수 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

외환위기 이후 대도시를 중심으로 노숙자들이 급증하여 이들이 심각한 사회문제로 등장하였다. 외국의 연구에 의하면 노숙자 중 상당수가 만성 정신질환을 앓고 있으며, 정신질환이 노숙의 원인 및 예후와 밀접한 관련이 있다고 한다. 그러나 국내에서는 아직 노숙자의 정신장애의 유병률에 관하여 알려진 바 없으므로 이에 대하여 조사하였다. 방법: 1998년 말부터 1999년 초까지 부산지역의 쉼터 두 곳에 거주하는 노숙자 216명을 대상으로 인구학적 자료에 대한 설문조사를 한 뒤 Structured Clinical Interview for DSM-Ⅳ(SCID)을 이용하여 Axis Ⅰ의 주요 정신장애를 진단하였다. 이들의 정신장애의 평생유병률 및 현재유병률을 국내 일반인구 및 외국 노숙자의 정신장애의 유병률과 비교하였다. 결과: DSM-Ⅳ Axis Ⅰ의 정신장애 중 기분장애, 정신병적 장애, 물질사용장애에 대한 진단 평가 결과 상기 정신장애의 전체 평생유병률은 60.1%, 현재유병률은 35.7%이었다. 그 중 주요우울장애의 평생유병률 이 22.5%로서 외국의 노숙자에 대한 역학연구 결과와 비교해 볼 때 높은 수준이었고 알코올 사용 장애의 평생유병률은 47.4%이었다. 정신병적 장애의 평생유병률은 3.8%이었고, 그 중에서도 정신분열병의 평생유병률은 1.9%이어서 외국의 노숙자에 대한 연구결과보다 낮은 편이었다. 결론: 국내 노숙자에서 기분장애와 물질사용장애가 주된 정신장애였으며 정신분열병 등 정신병적 장애의 유병률은 외국에 비해 낮은편이었다. 이러한 정신장애를 가지고 있는 노숙자에 대하여 접근하고 치료하기 위한 대책이 마련되어야 할 것이다. Objective:As homeless people increased in urban areas after the economic crisis in Korea, they became a serious social problem. Foreign research showed that many homeless people had chronic mental illnesses which were closely related with the cause and prognosis of homelessness. But very little was known about the prevalence of mental disorders in Korean homeless people. This study tried to capture the overall picture of mental disorders in homeless people. Method:The study subjects were 216 homeless people who stayed at two Pusan shelters between late 1998 and early 1999. Questionnaires on sociodemographic data were administered to the subjects, and then diagnoses of major DSM-IV Axis I mental disorders were made using Structured Clinical Interview for DSM-IV Axis I Disorders(SCID). The lifetime and current prevalence of mental disorders in this study were compared to those from other studies in Korean general population and in foreign homeless people. Results:The lifetime prevalence of major DSM-IV mental disorders(mood disorders, psy-chotic disorders, and substance use disorders) of 216 homeless people was 60.1%, and current prevalence was 35.7%. The lifetime prevalence of major depressive disorders was 22.5% which was higher than that of foreign studies. The lifetime prevalence of alcohol use disorder was 47. 4%. The lifetime prevalence of psychotic disorders was 3.8%, and among them the lifetime prevalence of schizophrenia was 1.9% which was lower than that of foreign studies. Conclusions: In Korean homeless people, mood disorders and substance use disorders were the main mental disorders and psychotic disorders such as schizophrenia were less than in foreign homeless people. The plans to approach and treat homeless people with mental disorders should be made.

천연 Zeolite를 이용한 매립지 침출수의 고농도 암모니아성 질소 제거에 관한 연구

오재일,홍성효,이선구,최영화,안봉규 중앙대학교 기술과학연구소 2002 기술과학연구소 논문집 Vol.32 No.-

천연 제올라이트의 일종인 Clinoptilolite를 이용하여 매립지 침출수내의 암모니아성 질소를 제거하는 실험을 수행하였다. 고정상 칼럼을 이용한 인공 침출수와 실제 침출수 조건의 실험에서 배출농도가 유입농도의 5%인 시점을 파과점으로 상정할 때, 인공 침출수 조건에서의 파괴시간은 53hr, 실제 침출수 조건에서의 파과시간은 32.5hr으로 나타났다. 또한, 허용 파과점 및 소모점에서의 제올라이트 100g(건조중량)당 제거된 암모늄 이온 성분량은 인공 침출수의 경우 각각 79.30meq/100g, 93.34meq/100g이었으며, 실제 침출수의 경우 각각 48.60meq/100g, 57.60meq/100g으로 나타났다. 침출수 조건의 경우 인공 침출수에 비해 약 39% 가량의 제거 효율 저하를 보이고 있으며, 이는 실제 침출수에 존재하고 있는 공존 양이온의 영향으로 사료된다. 실제 침출수 내에서 공존 양이온의 용출 특성을 보면, Na, Ca, Mg의 용출량은 증가하나 K는 용출량이 감소하는 것으로 나타났다. This experiment was conducted to remove the ammonia nitrogen in the landfill leachate by Clinoptilolite which is a sort of the natural zeolite. In fixed-bed column test driven in the artificial and actual condition of the leachate, when the ejection concentration was supposed the point of 5% of the initial concentration as the breakthrough point, the breakthrough time was 53hr in the artificial condition of the leachate and was 32.5hr in the actual condition of the leachate. The ingredient volume of the removed ammonium ion per 100g(based upon the dry weight) of the zeolite in the allowed breakthrough point and exhaustion point were individually 79.30meq/100g, 93.34meq/100g in the artificial leachate and 48.60meq/100g, 57.60meq/100g in the actual leachate. In case of the actual condition of the leachate, the removal efficiency was decreased by 39% than the artificial condition of the leachate, and it seems to be caused by the coexist cation in the actual leachate. The ejection characteristics of the coexist cation in the actual leachate was observed that Na, Ca, Mg was increased and K was decreased.

초음파 펄스에코 데이터 기반 3차원 시각화 방법론

권정현,장홍래,성제중,안형근,장순재,송문호 한국비파괴검사학회 2003 학술대회 논문집 Vol.- No.1

The nondestructive testing using ultrasonic pulse-echo data is an effective test methodology esperially for metal structure. Typically, the ultrasonic pulse-echo data is processed and the results are shown in A-scan, B-scan or C-scan formats. Upon viewing B-scan and C-scan data the viewer is able to identify the location of faults as well as their rough dimension. In this paper, we evaluate the applicability of various 3-D visualization methods frequently used in medical imaging, namely, surface rendering (SR), volume rendering (VR) and maximum intensity projection (MIP), for nondestructive testing purposes. Such 3-D visualization of ultrasonic pulse-echo data enables easier identification of the location and dimension of faults more accurately.

외상에 이한 혈관 손상 환자에서 중재적 방사선 시술에 의한 치료

최지은,조용필,안제홍,한명식,장혁재,김용호,최윤백 대한혈관외과학회 2004 Vascular Specialist International Vol.20 No.1

Endovascular Management of Iliofemoral Deep Venous Thrombosis due to Iliac Vein Compression Syndrome in Patients with Protein C and/or S Deficiency

Ahn Je Hong,Han Myoung Sik,Jang Hyuk Jai,Kim Yong Ho,Lee Sung Gyu,Choi Soo Jung,Kim Hee Jeong,Kwon Tae Won,Cho Yong Pil 대한의학회 2004 Journal of Korean medical science Vol.19 No.5

Cellular and Molecular Changes Associated With Inhibitory Effect of Pioglitazone on Neointimal Growth in Patients With Type 2 Diabetes After Zotarolimus-Eluting Stent Implantation

Hong, Soon Jun,Kim, Sung Tae,Kim, Tae-Jin,Kim, Eun-Ok,Ahn, Chul-Min,Park, Jae Hyoung,Kim, Je Sang,Lee, Kyung-Mi,Lim, Do-Sun Ovid Technologies Wolters Kluwer -American Heart A 2010 Arteriosclerosis, thrombosis, and vascular biology Vol.30 No.12

High-Efficiency Bidirectional Three-Phase LCC Resonant Converter With a Wide Load Range

Ahn, Suk-Ho,Jang, Sung-Roc,Ryoo, Hong-Je IEEE 2019 IEEE TRANSACTIONS ON POWER ELECTRONICS - Vol.34 No.1

<P>This paper details the design and implementation of an efficient 4-kW bidirectional converter with a wide load range, based on a three-phase LCC resonant converter operated in a continuous conduction model, which has a number of advantages pertaining to a bidirectional power supply. The voltage boost-up function yields a high voltage gain without increasing the transformer turn ratio. The high switching frequency, which is achievable by using the soft-switching condition and multiphase operation, decreases the output ripple and helps minimize the size of the output filter, as the requirement for a filter changes after the power flow. Moreover, this reduction in the size of the filters yields economic advantages. In addition, because of the synchronous rectifier operation employed during switching, the conduction loss in the rectifier diode of the proposed converter is low. The direction of the output power can be changed easily, using phase control. The implemented power converter is connected to a 320-V rated generator on one side and 28-V lead-acid batteries on the other side. The functionality of the proposed converter is verified in experiments. We confirmed the high performance of the developed converter in terms of efficiency (92.2%), operable load range (0–12.5 A in step-up, and 0–142 A in step-down), and voltage ripple (0.05%).</P>

Prospective randomized comparison of clinical and angiographic outcomes between everolimus-eluting vs. zotarolimus-eluting stents for treatment of coronary restenosis in drug-eluting stents: intravascular ultrasound volumetric analysis (RESTENT-ISR trial)

Hong, Soon Jun,Ahn, Chul Min,Kim, Byeong-Keuk,Ko, Young-Guk,Hur, Seung-Ho,Yu, Cheol Woong,Lee, Seung-Jin,Choi, Cheol Ung,Kim, Je Sang,Yoon, Jung-Han,Hong, Young Joon,Choi, Jae-Woong,Choi, Seung-Hyuk,J The European Society of Cardiology 2016 European heart journal Vol.37 No.45

<P><B>Aims</B></P><P>At present no proven standard treatment for drug-eluting stent (DES) restenosis is available, and the efficacy and safety of everolimus-eluting stent (EES) and zotarolimus-eluting stent (ZES) for DES restenosis are limited. The purpose of this prospective, randomized 9-month intracoronary ultrasound (IVUS) and 3-year clinical follow-up study was to compare the effects of EESs and ZESs on neointima volume and major adverse cardiovascular events (MACEs) such as death, myocardial infarction (MI), target lesion revascularization (TLR) and stent thrombosis in DES restenosis patients.</P><P><B>Methods and results</B></P><P>Patients were eligible for this study if they were between 40 and 75 years old with in-stent restenosis >50% by quantitative coronary angiographic analysis in DES or within 5 mm of the stent edges with signs of ischaemia. Eligible patients (<I>n</I> = 304, 146 women and 158 men) were randomly assigned to receive either EES (158 patients) or ZES (146 patients). The primary endpoint of the study was to compare neointima volume between the EES and ZES groups at the 9-month follow-up IVUS. MACEs, including death, non-fatal MI, stent thrombosis and the need for repeated TLR within 3 years, were noted. The 9-month angiographic and IVUS follow-up showed no significant differences in late lumen loss (0.40 ± 0.56 vs. 0.45 ± 0.61 mm, <I>P</I> = 0.57, respectively) and neointima volume (0.51 ± 0.48 vs. 0.56 ± 0.54 mm<SUP>3</SUP>/1 mm, <I>P</I> = 0.47, respectively) in the EES and the ZES groups. Composite MACEs such as death, MI, stent thrombosis and TLR during 3-year follow-up were comparable between the two groups [15.8% (<I>n</I> = 25) in the EES group and 22.6% (<I>n</I> = 33) in the ZES group, <I>P</I> = 0.276], independent of <I>de novo</I> DES type, sex, age, body mass index, presence of diabetes, hypertension and dyslipidaemia.</P><P><B>Conclusions</B></P><P>Patients with first- and second-generation DES restenosis, both EES and ZES implantation were effective and safe in reducing neointima volume and late loss with a comparable rate of MACEs independent of cardiovascular risk factors. </P>

Design and Comparison of Capacitor Chargers for Solid-State Pulsed Power Modulator

Hong-Je Ryoo,Suk-Ho Ahn,Ji-Woong Gong,Sung-Roc Jang IEEE 2013 IEEE transactions on plasma science Vol.41 No.10

<P>This paper describes the design, implementation, and comparison of high-voltage capacitor chargers for a solid-state pulsed power modulator (SSPPM). The three different converter topologies are a series resonant converter operating at a discontinuous conduction mode with switching frequency control (SRC_DCM_SFC), a series resonant converter operating at a continuous conduction mode with phase shifted pulse width modulation control (SRC_CCM_PSPWMC), and a series-parallel resonant converter operating at the CCM with SFC (SPRC_CCM_SFC). On the basis of these converter topologies, 10-kWaverage high-voltage capacitor chargers are designed for the three types of SSPPMs, which have the following maximum output specifications: 1) SRC_DCM_SFC: 60 kV, 300 A, 3 kpps, and 50 μs; 2) SRC_CCM_PSPWMC: 10 kV, 50 A, 50 kpps, and 10 μs; and 3) SPRC_CCM_SFC: 40 kV, 150 A, 7 kpps, and 10 μs. Although the pulse output specifications are different, it is worth comparing the resonant inverter topologies and the control methods from the viewpoint of the losses, control characteristics, and merits and demerits of the high-voltage capacitor chargers. From the analysis and investigation of the three resonant inverters, the design procedure, including the determination of the resonant tank parameters, is provided, which considers the design of the high-voltage capacitor charger. PSPICE simulation is used to elucidate the effects of the resonant tank structure and its parameters, and the resonant current waveform and losses of the Insulated Gate Bipolar Transistor are compared. Finally, experiments for each charger are performed under various load conditions, and the comparison results of the three capacitor chargers, including the conduction and switching losses, control characteristics, and overall efficiency, are discussed in this paper.</P>

Treatment Outcomes of Rituximab Plus Hyper-CVAD in Korean Patients with Sporadic Burkitt or Burkitt-like Lymphoma: Results of a Multicenter Analysis

Hong, Junshik,Kim, Seok Jin,Ahn, Jae-Sook,Song, Moo Kon,Kim, Yu Ri,Lee, Ho Sup,Yhim, Ho-Young,Yoon, Dok Hyun,Kim, Min Kyoung,Oh, Sung Yong,Park, Yong,Mun, Yeung-Chul,Do, Young Rok,Ryoo, Hun-Mo,Lee, Je Korean Cancer Association 2015 Cancer Research and Treatment Vol.47 No.2

<P><B>Purpose</B></P><P>This study was conducted to evaluate outcomes in adult patients with Burkitt lymphoma (BL) or Burkitt-like lymphoma treated with an rituximab plus hyper-CVAD (R-hyper-CVAD) regimen by focusing on tolerability and actual delivered relative dose intensity (RDI).</P><P><B>Materials and Methods</B></P><P>Patients ≥ 20 years of age and pathologically diagnosed with BL or Burkitt-like lymphoma were treated with at least one cycle of R-hyper-CVAD as the first-line treatment in this study. Eligible patients’ case report forms were requested from their physicians to obtain clinical and laboratory data for this retrospective study.</P><P><B>Results</B></P><P>Forty-three patients (median age, 51 years) from 14 medical centers in Korea were analyzed, none of which were infected with human immunodeficiency virus. The majority of patients had advanced diseases, and 24 patients achieved a complete response (75.0%). After a median follow-up period of 20.0 months, 2-year event-free and overall survival rates were 70.9% and 81.4%, respectively. Eleven patients (25.6%) were unable to complete the R-hyper-CVAD regimen, including six patients due to early death. The RDIs of adriamycin, vincristine, methotrexate, and cytarabine were between 60% and 65%, which means less than 25% of patients received greater than 80% of the planned dose of each drug. Poor performance status was related to the lower RDIs of doxorubicin and methotrexate.</P><P><B>Conclusion</B></P><P>R-hyper-CVAD showed excellent treatment outcomes in patients who were suitable for dose-intense chemotherapy. However, management of patients who are intolerant to a dose-intense regimen remains problematic due to the frequent occurrence of treatmentrelated complications.</P>