비소중독된 흰쥐의 장기중 비소 축적에 미치는 팔진탕의 영향

임종필,서은실,김훈,강창수 又石大學校 1998 論文集 Vol.20 No.-

Sodium arsenate and Paljin-Tang extract, a herbal restorative were treated p.o. 20 ㎎/㎏ and 500 ㎎/㎏, respectively, and concurrently to rats, and examined the variation of body weight, the accumulation of arsenic in organs. The results obtained in this study were as follows: 1. Paljin-Tang extract (PJT) resulted in the increase of body weight and the increase ratio of body weight in arsenic-treated group was dropped but the group of concurrent administration with PJT showed significant recovery. 2. The accumulation of arsenic in liver of arsenic-treated group increased but the group of concurrent administration with PJT showed significant decrease compared with arsenic-treated group. 3. The ratio of liver weight / body weight of arsenic-treated group increased but the group of concurrent administration with PJT showed significant decrease compared with arsenic-treated group.

담즙 역류성 위염에서의 Helicobacter pylori 감염과 조직학적 소견

임종필,양종인,최기돈,김병관,김주성,이국래,이동호,장미수,정현채,송인성 대한소화기내시경학회 2003 Clinical Endoscopy Vol.26 No.1

Backgroud/Aims: The role of Helicobacter pylori in bile reflux gastritis (BRG) is uncertain. We show the role of H. pylori and pathology in BRG. Methods: Thirty seven patients, including 5 patients who had undergone subtotal gastrectomy, were diagnosed with BRG by gastroscopic findings of bile-stained mucosa with hyperemia/ erosions. We measured total bile acid (TBA) concentration and compared the H. pylori positivity between BRG patients and 70 non-BRG patients. We showed how often we could see the pathologic findings of reactive gastritis in BRG and compared the grade of lymphoplasma cell and neutrophil infiltration between H. pylori positive and negative group in BRG. Results: TBA concentration of 10 patients was 7,376.7 5,482.6μmol/L. H. pylori positive rate of BRG was 45.9% and that of non-BRG was 70% (p=0.015). The gastric pit elongation and tortuosity were found only in 3 cases with gastric surgery. The grade of lymphoplasma cell and neutrophil infiltration was 2.41 0.51 and 1.88 0.86 in H. pylori positive BRG and 1.55 0.69 and 0.55 0.76 in H. pylori negative BRG, respectively (p<0.001). Conclusions: H. pylori infection in BRG was lower than that in non-BRG. The gastric pit elongation and tortuosity of BRG were not seen often. The lymphoplasma cell and neutrophil infiltration were relatively sparse in H. pylori negative BRG. (Korean J Gastrointest Endosc 2003;26:8-14) 목적: 담즙 역류성 위염은 반응성 위염의 한 종류로, 내시경 검사에서 위 내에 담즙이 고여있거나 점막에 염색되어 있으면서, 점막의 발적, 미란, 취약성이 관찰된다. 조직학적으로 위소와의 과증식, 모세혈관의 확장, 경미한 급만성 염증 세포의 침윤 등의 특징을 나타낸다. 많은 연구에서 담즙 역류성 위염과 Helicobacter pylori (H. pylori) 감염의 관계에 대해서 다양한 결과를 보고하고 있다. 이에 저자들은 담즙 역류성 위염 환자에서의 H. pylori의 감염률, 조직학적 변화 및 역할에 대해서 알아보고자 하였다. 대상 및 방법: 위장 증상을 호소하여 시행한 상부 위장관 내시경 검사에서 담즙 역류성 위염으로 진단받은 37명을 대상으로 하였으며, 이 중에는 위암으로 위아전절제술을 받은 5명을 포함하였다. 담즙 역류가 없는 만성 위염 환자 70명을 대조군으로 하였다. 상부 위장관 내시경 검사를 통해 10명의 환자에서 위액을 흡인하여 총 담즙산 농도를 측정하였다. H. pylori의 감염은 조직검사 및 신속 요소분해효소 검사를 시행하여 확인하였고, 환자군과 대조군의 감염 양성률을 비교하였다. 환자군에서는 위소와의 과증식, 위선의 위축, 장형화생, 위소와의 연장과 구부러짐(gastric pit elongation and tortuosity)의 빈도를 평가하였고, H. pylori 감염 양성군과 음성군 간의 호중구와 림프형질 세포의 침윤 정도를 비교하였다. 결과: 10명의 담즙 역류성 위염 환자에서 측정한 위액 내의 총 담즙산 농도는 7,376.7±5,482.6 μmol/L이었다. 환자군의 H. pylori 감염 양성률은 45.9%였고 대조군의 H. pylori 감염 양성률은 70%이었다(p=0.015). 위소와의 연장과 구부러짐은 3예(8.1%)에서 관찰되었으며 위아전절제술을 받은 환자들에서만 관찰되었다. H. pylori 감염 양성군의 림프형질 세포의 침윤 정도는 2.41±0.51로 H. pylori 감염 음성군의 1.55±0.69보다 높았다(p<0.001). H. pylori 감염 양성군의 호중구의 침윤 정도는 1.88±0.86으로 H. pylori 감염 음성군의 0.55±0.76보다 높았다(p<0.001). 결론: 담즙 역류성 위염 환자에서의 H. pylori의 감염률은 담즙 역류가 동반되지 않은 위염 환자보다 낮았다. 담즙 역류성 위염의 특이적인 조직학적 소견인 위소와의 연장과 구부러짐은 흔하게 관찰되지 않았다. 호중구와 림프형질 세포의 침윤은 H. pylori 감염 양성군이 감염 음성군보다 많았다.

태충혈(太衝穴)에 대(對)한 문헌적(文獻的) 고찰(考察)

임종필,성낙기,Im, Jong-Pil,Seong, Nak-Gi 대전대학교 한의학연구소 1995 한의학연구소 논문집 Vol.4 No.1

補中益氣湯이 납中毒된 흰쥐의 臟器重量에 미치는 影響

임종필,남궁동,강창수,강태욱 又石大學校 1994 論文集 Vol.16 No.-

Lead acetate and Bojungiki-tang extract, a herbal restorative were treated p. o. 40㎎/㎏ and 500㎎/㎏ respectively and concurrently to mouse, and examined variation of body weigh, accumulation of lead in organs of rats. The results obtained in this study are as follows: 1. Bojungiki-tang extract(BIT) resulted increase of body weight and the increase ratio of body weight in lead-treated group was dropped but the group of concurrent administration with BIT showed significant recovery. 2. The accumulation of lead in liver of lead-treated group increased but the group of concurrent administration with BIT showed significant decrease. 3. The ratio of liver weight/body weight of lead-treated group increased but the group of concurrent administration with BIT showed significant decrease. These results on the whole indicated that concurrent administration with BIT sowed significant recovery from the toxicity of lead-treated group.

鑛物生藥의 修治에 대한 分析硏究

林鍾弼,金勳 又石大學校 1993 論文集 Vol.15 No.-

"Juk Yom" was originated from Korean folk remedies with history of thousands of years. From the ancient days, people used parched salt by burning bamboo trunks stuffed with sea salt. This is a simple form of "Juk Yom" salt. Cinnarbar is a mineral composed of red mercuric sulfide after fire processing, which is used as tranquillizers by restraing excitation of the central nervous system. Juk Yom and cinnarbar were analysed by X-ray diffractor. The experimental results were summerized as followings; 1) In Juk Yom sample, the lattice parameter was in good agreement with that of J.C.P.D.S. card of sodium chloride. 2) In cinnarbar sample, the lattice parameter was in good agreement with that of J.C.P.D.S. card of mercuric sulfide. 3) The crystal structures of mineral drugs were not changed by fird processing.

Transformer-Reuse Reconfigurable Synchronous Boost Converter with 20 mV MPPT-Input, 88% Efficiency and 37 mW Maximum Output Power

임종필,문승언,여준기 한국전자통신연구원 2016 ETRI Journal Vol.38 No.4

This paper presents a transformer-based reconfigurable synchronous boost converter. The lowest maximum power point tracking (MPPT)-input voltage and peak efficiency of the proposed boost converter, 20 mV and 88%, respectively, were achieved using a reconfigurable synchronous structure, static power loss minimization design, and efficiency boost mode change (EBMC) method. The proposed reconfigurable synchronous structure for high efficiency enables both a transformer-based self-startup mode (TSM) and an inductor-based MPPT mode (IMM) with a power PMOS switch instead of a diode. In addition, a static power loss minimization design, which was developed to reduce the leakage current of the native switch and quiescent current of the control blocks, enables a low input operation voltage. Furthermore, the proposed EBMC method is able to change the TSM into IMM with no additional time or energy loss. A prototype chip was implemented using a 0.18-μm CMOS process, and operates within an input voltage range of 9 mV to 1 V, and an output voltage range of 1 V to 3.3 V, and provides a maximum output power of 37 mW.

화피의 충치균과 치주질환균에 대한 항균활성 및 항염효과

임종필 한의병리학회 2011 동의생리병리학회지 Vol.25 No.4

K-Pop 세대별 아이돌 그룹 코러스의 멜로디 전개 기법

임종필,정재윤 한국엔터테인먼트산업학회 2023 한국엔터테인먼트산업학회논문지 Vol.17 No.6

The popularity of the Korean Wave continues to increase around the world. As an image that comes to mind when it comes to korea selected by overseas consumers, K-Pop was ranked first for five consecutive years, and the addictive chorus was selected as the reason why K-Pop is popular. Therefore, this study aims to derive the characteristics of the K-Pop idol group chorus. The research scope of this study was selected through three stages on the music portal site Melon’s historical chart, and a total of 120 subjects were analyzed. As a result of the analysis, it was confirmed that the K-Pop idol group chorus began with the first generation and proceeded with each generation, and the technique of reducing or simply repeating the transformation of a given motive was frequently used. As a result of this study, the characteristics and changes of the K-Pop idol group chorus by generation were confirmed by a method called melody development technique.

복강 내 종괴로 나타난 림프절 전이를 동반한 분화형 점막 위암 1예

임종필,강정묵,이혁준,김상균,김주성,정현채,송인성 대한소화기내시경학회 2007 Clinical Endoscopy Vol.35 No.6

In early gastric cancer, the most important prognostic factor is the presence or absence of a lymph node metastasis that is associated with the tumor size, histopathological differentiation, depth of tumor invasion and lympho-vascular invasion. A small sized differentiated mucosal cancer without a lympho-vascular invasion or histological ulceration rarely metastasizes to the lymph node. Herein, we report a case of a lymph node metastasis that is presented as an intra-abdominal mass in a 2.5 cm-sized differentiated mucosal cancer without ulceration or lympho-vascular invasion. (Korean J Gastrointest Endosc 2007;35:429-434) 조기 위암에서 림프절의 전이 여부는 환자의 예후에 가장 중요한 요인으로 림프절 전이는 종양의 크기, 분화도, 침범 깊이, 림프관과 혈관의 침범 여부 등과 연관이 있다. 즉, 크기가 작고 림프관 및 혈관을 침범하지 않은 분화형 점막암은 거의 림프절 전이를 하지 않으며, 궤양을 동반하지 않은 경우에는 종양의 크기에 상관없이 림프절 전이는 드문 것으로 알려져 있다. 최근 저자들은 궤양을 동반하지 않은 2.5 cm 크기의 점막에 국한된 분화암에서 림프관 및 혈관의 침범 없이 복강 내 종괴의 형태로 림프절 전이를 보인 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

PS/PMMA 블렌드의 유변학적 성질과 Morphology와의 관계

임종필,한민수,정현철,김우년 한국고분자학회 2000 한국고분자학회 학술대회 연구논문 초록집 Vol.2000 No.4