노년기 성(sexuality)에 대한 노인들의 인식 유형

황순정 ( Soon Jeong Hwang ),신원식 ( Won Shik Shin ) 경남대학교 인문과학연구소 2014 人文論叢 Vol.35 No.-

이 연구는 노년기 성에 대한 노인들의 주관적 인식을 유형화하고, 그 특성을 분석하는 것이 목적이다. 유형별 특성을 통해 자신과 주변 사람들이 노년기 성에 대해 올바른 이해와 긍정적 태도를 가질 수 있는 방안을 모색해 본다. 노년기 성에 관한 엄선된 진술문 27문항을 가지고, 31명의 노인들에게 Q 분류를 하게 한 결과, 세 가지 유형이 도출되었다. 첫째, 적극 수용형 으로, 이 유형은 노년기 성생활을 기본적인 권리로 인식하고, 삶의 필수조건으로 생각한다. 둘째, 회피형 으로 명명하였는데, 이 유형은 노년기 성에 대해 부정적 감정을 갖고 있으며, 사회적 편견이나 개인의 부정적 경험으로 인해 성생활을 회피하는 것으로 나타났다. 셋째, 본능 추구형 이다. 이 유형은 노년기 성은 본능적인 욕구를 충족시키는 것이며, 육체적 정신적 건강을 위해 필요하다고 생각한다. 연구결과를 토대로 한 사회복지실천에 대한 함의는 다음과 같다. 첫째, 노년기 성에 대한 올바른 이해와 인식을 위한 교육이 필요하다. 둘째, 노년기 성에 대해 부정적 인식을 갖고 있는 노인들을 위한 전문상담이 필요하다. 셋째, 노인들이 상호 간 친밀감을 형성할 수 있는 기회제공이 확대되어야 한다. 마지막으로, 노년기 성에 대한 가족 및 사회의 긍정적 수용이 필요하며, 이를 위해 대중매체의 역할이 재정립되어야 한다는 것이다. The purpose of this study is to identify the subjective perception types of the elderly on the senior sexuality, categorize them, and suggest possible ways to improve senior sexuality perception. A questionnaire of 27 statements on senior sexuality was administered to 31 elderly, using Q methodology for data analysis. Through Q methodology, three types and features of their subjective perception about senior sexuality were obtained:The three types are Highly receptive type, Evasive type, and Instinct seeking type. The results of this study have implications for social welfare practices as follows. Firstly, the correct understanding and perception about senior sexuality training is necessary. Secondly, the elderly who have negative perceptions on senior sexuality need professional counseling. Thirdly, the elderly need to be given opportunities to mutual intimacy. Finally, the positive acceptance about senior sexuality is necessary and the role of the media needs to be re-established.

Expression of Growth Factors and Secretory Leukocyte Protease Inhibitor (SLPI) in RAW264.7 Cells after Lipopolysaccharide (LPS) Stimulation

손욱희,최백동,정순정,왕관림,황호길,정문진,Son, Wook-Hee,Choi, Baik-Dong,Jeong, Soon-Jeong,Wang, Guan-Lin,Hwang, Ho-Keel,Jeong, Moon-Jin Korean Society of Electron Microscopy 2007 Applied microscopy Vol.37 No.2

분비백혈구단백분해효소억제제 (SLPI)와 여러 성장인자들은 상처 감염이나 박테리아 침입 시 일어나는 염증반응에 서로 관계가 있지만, 대식세포에서 LPS 자극시 SLPI와 VEGF, bFGF, PDGF 등과 같은 성장 인자들의 발현관계에 대해서는 아직까지 알려진 연구 결과가 없다. 따라서 본 연구는 대식세포 세포주로 알려진 RAW264.7 세포에 SLPI 발현의 적정농도인 LPS에 반응하는 SLPI 및 성장 인자들과 세포외부기질이 발현을 규명하고자 하였다. 역전사효소 중합반응(RT-PCR)과 면역학적 단백질 검출법(Western blotting)은 LPS 처리 후 SLPI와 몇몇 성장인자들 (VEGF, bFGF, PDGF)와 제1형 아교질 mRNA와 SLPI 단백질의 검출을 위해 수행하였다. RAW264.7 세포 주를 mL 당 100 ng의 LPS에 각각 30분, 60분, 90분, 24시간, 48시간동안 노출시켰다. RT-PCR 결과 SLPI mRNA는 시간이 지남에 따라 점점 발현 양이 증가하였고 VEGF와 PDGF mRNA는 초기에 높은 발현 양상을 보였다. 그러나 bFGF와 I형 아교질의 발현은 매우 미약하게 나타났다. SLPI 단백질 발현 역시 mRNA 수준과 마찬가지로 증가하는 양상을 보였는데, 배양액내의 SLPI 단백질양은 전체적으로 감소하는 경향을 보였다. 또한 광학현미경 관찰과 주사전자현미경 관찰결과, LPS가 RAW264.7 세포주의 형태학적인 변화를 일으킴을 확인하였다. 본 결과를 종합하면 SLPI 발현증가의 적정 농도라 생각되는 100ng의 LPS에 의해서 발현되는 VEGF나 PDGF는 SLPI의 발현에 관계가 있는 것으로 생각되지만 추후에 이들 인자들의 단백질이나 유전자 도입을 통하여 발현 관계를 명확히 확인해야 하는 추가실험이 진행되어야 할 것이다.하게 된다.토끼 면역항체를 선모충유충 조직항원에 반응시켰을 때 충체의 표피와 기저층 그리고 EIM 및 stichocyte의 ${\alpha}_0\;{\alpha}_1$ 과립에 황금입자가 표지되었다. 따라서 1일 동안 배설되는 분비배설항원은 선모충 유충의 표피와 stichocyte의 ${\alpha}_0\;{\alpha}_1$ 과립에서 유도되는 반면에 3일 동안 배설되는 분비배설항원은 표피와 stichocyte의 ${\alpha}_0$ 과립에서 유도되고, 선모충유충 감염후 1주, 4주에 실험쥐에서 형성되는 감염항체는 선모충의 표피와 기저층 그리고 EIM에서 분비되는 항원에 의하여 생성된다. 이상의 결과로 선모충의 분비배설항원과 감염항원은 선모충 유충의 표피와 EIM및 stichocyte의 ${\alpha}_0\;{\alpha}_1$ 과립에서 유도되며 이들은 45 kDa 단백을 포함하고 있는 것으로 생각된다.성하고 있는 세포들에는 세포질이 어두운 세포와 밝은 세포가 있었으며, 세포질내에는 전자밀도가 높은 분비과립이 관찰되었다. 전체적인 특징은 눈물샘분비세포 중 장액세포의 것과 비슷하였으나, 과립의 크기는 작았다. 분비관을 구성하는 세포들 사이에도 연접복합체가 매우 잘 발달되어 있었다. 샘포에서 사이관으로 이행되는 곳에서도 샘포세포와 사이관세포 사이에서도 연접복합체가 관찰되었다. 분비관세포의 분비과립 가운데는 중심부분에 전자밀도가 더 높은 중심을 가진 다른 모양의 과립이 관찰되기도 하였다. 의해 사망한 환자는 없었다. 결 론: 자궁경부암 환자에 항암화학요법과 동시에 외부 방사선조사와 고선량률의 강내조사를 시행한 결과 독성이 심하지 않고 국소제어율과 단기 생존율이 양호하여 안전하고 효율적인 치료방법으로 생각된다. Secretory leukocyte protease inhibitor (SLPI) was known as one of bacterial lipopolysaccharide (LPS)-induced products of macrophage. Macrophages play an important role in the development of inflammatory responses by secreting an array of cytokines and chemokines in a tissue microenvironment. To identify the function and relationship between potent growth factors and SLPI after LPS stimulation, we conducted reverse transcriptase polymerase chain reaction (RT-PCR) and Western blots for the detection of mRNA and protein expression of SLPI and growth factors such as VEGF, PDGF, bFGF after 100 ng LPS stimulation on the RAW264.7 cells. The result of RT-PCR was showed SLPI mRNA expression was increased from 60 min to 48h in RAW 264.7 cells after incubation with LPS. VEGF and PDGF mRNA was expressed highly at initial stage by LPS stimulation. The mRNA of bFGF and type I collagen was very weakly expressed after LPS stimulation. SLPI protein level was increased likely the mRNA levels in RAW 267.7 cells. Additionally, phase contrast and scanning electron microscopic observation demonstrated that the LPS induce the change of morphology of the RAW264.7 cells. From these results, it suggest that expression of SLPI by LPS treatment may associate with VEGF and PDGF expression in RAW264.7 cells.

말초신경 재건을 위한 인회석 박막 코팅 미세공성 신경재생관(nerve conduit)의 개발

이종호(Jong-Ho Lee),황순정(Soon-Jeong Hwang),최원재(Won-Jae Choi),김성민(Soung-Min Kim),김남열(Nam-Yeol Kim),이은진,안강민(Kang-Min Ahn),명훈(Hoon-Myung),서병무(Byoung-Moo Seo),최진영(Jin-Young Choi),정필훈(Pill-Hoon Choung),김명진(Myu 대한구강악안면외과학회 2003 대한구강악안면외과학회지 Vol.29 No.3

This study was performed to develop a useful nerve conduit which provides favorable environment for Schwann cell viability and proliferation. Milipore membrane of 0.45μm pore size was selected because it permits nutritional inflow from the outside of the conduit and prevents from invading the fibrotic tissue into the conduit. The membrane was rolled and sealed to form a conduit of 2mm diameter and 20mm length. To improve the axonal regeneration and to render better environment for endogenous and exogenous Schwann cell behaviour, the microgeometry and surface of conduit was modified by coating with thin film of calcium phosphate. Cellular viability within the conduit and attachment to its wall were assessed with MTT assay and SEM study. Milipore filter conduit showed significantly higher rate of Schwann cell attachment and viability than the culture dish. However, the reverse was true in case of fibroblast. Coating with thin film of low crystalline calcium phosphate made more favorable environment for both cells with minimal change of pore size. These findings means the porous calcium phosphate coated milipore nerve conduit can provide much favorable environment for endogenous Schwann cell proliferation and exogenous ones, which are filled within the conduit for the more advanced strategy of peripheral nerve regeneration, with potential of reducing fibrotic tissue production

가토모델에서 배양 구강상피를 이용한 근-점막 피판의 형성에 관한 연구

신영민,정헌종,안강민,박희정,성미애,김성민,황순정,김명진,장정원,김성포,양은경,송계영,이종호,Shin, Young-Min,Chung, Hun-Jong,Ahn, Kang-Min,Park, Hee-Jung,Sung, Mi-Ae,Kim, Soung-Min,Hwang, Soon-Jung,Kim, Myung-Jin,Jahng, Jeong-Won,Kim, Sung-P 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.3

Purpose : Extensive defect of oral and maxillofacial area is usually reconstructed with composite flap including skin paddle. However, if the defects are lined with only skin components, the mucosa's role in mastication and texture are not restored. Furthermore, stiffness and hair-growing prevent denture rehabilitation and good oral hygiene. This study was performed to overcome the disadvantages of composite soft tissue flaps including the skin and to make a model for myo-mucosal flaps. Materials and methods : Buccal mucosa sized $0.5\times1.0\;cm^2$ from New Zealand rabbit (around 1.5kg) was harvested and cultivated by the modification of Rheinwald and Green's keratinocyte culture method. Cultured mucosa was grafted on the fascia of latismus dorsi as form of mucosal sheet. After 7, 10, 14 days, the myomucosal flap was excised and evaluated under light microscope with H & E and immunohistochemical staining. As control group, harvested buccal mucosa from rabbit was transplanted to gracilis muscle(n=6). Results : From 7 days after prelamination, the basal layer of the grafted mucosa resembled that of normal mucosa. As control group, transplanted mucosa had original shape but there's slight inflammatory reaction. Prelaminated mucosa has 19.8$\pm$4.59 cell layers and some samples have more than 20 layers. The expression rate of PCNA was relatively strong (42.9%$\pm$14.1) at the basal layer of grafted mucosa and the laminin was found at the basal layer. On the contrary, prelaminated mucosa at 10 days showed moderate expression rate of PCNA(32.4%$\pm$4.62). We found the mucosal layer was somehow disappeared and there is strong inflammatory reaction. After 14 days prelamination, the grafted oral keratinocytes were almost disappeared and expression of PCNA was not observed. Conclusion : We can make 75 fold large mucosal($3850mm^2$) sheet from small samples of mucosa $(50mm^2)$. Epithelial sheet that grafted on the fascia of muscle underwent differentiation and proliferation. But after 10, 14 days, there was strong inflammatory reaction and the grafted mucosa was destroyed from surface layer. In rabbit model, transfer of fascio-mucosal flap should be done from 7 to 10 days after prelamination.

인간 무세포성 진피기질 위에 배양한 가토 구강각화상피세포의 중충화와 기저막 형성에 관한 연구

김용덕,안강민,염학렬,정헌종,김성민,장정원,성미애,박희정,황순정,이종호,Kim, Yong-Deok,Ahn, Kang-Min,Yum, Hak-Yeol,Chung, Hun-Jong,Kim, Soung-Min,Jang, Jeong-Won,Sung, Mi-Ae,Park, Hee-Jung,Hwang, Soon-Jung,Lee, Jong-Ho 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.6

To assess the clinical applicability of bio-artificial mucosa which was made with autologous oral keratinocytes and human acellular dermal matrix, the formation of basement membrane and stratification of oral keratinocytes were evaluated. Six New Zealand white rabbits (around 2kg in weight) were anesthetized and its buccal mucosa was harvested (1.0 $\times$ 0.5cm size). Oral keratinicytes were extracted and cultured primarily with the feeder layer of pretreated NIH J2 3T3 fibroblast. These confluent cells were innoculated on the human acellular dermal matrix and cultured in multiple layer by air-rafting method. After 3, 5, 7, 10, 14 days of culture, each cultured bio-artificial mucosa was investigated the number of epthelial layer of by H&E stain and toluidine blue stain. The immuhohistochemical methods were used to evaluate the cell division capacity, the formation of basement membrane, and it's property of specific cells (PCNA, cytokeratin 14, laminin). Transmission electromicroscopy was used for the attachment between cells and matrix with the number of hemidesmosome. In result, the numbers of layer of stratified growth of oral keratinocyte cultured on the human acellular dermal matrix and the number of hemidesomal attachment between epithelial cells and human acellular dermal matrix were similar to the layers of normal oral mucosa after 10 days of culture. The cell division rate, basement membrane formation and proliferation rate increased as culture period increased. With these results, bio-artificial mucosa with autologous oral epithelial cells cultured on the acellular dermal matrix had clinically adaptable properties after 10 days' culture and this new bio-artificial mucosa model with relatively short culture time can be expected clinical applicability.

두경부 감염증에 나타난 내경정맥혈전증의 장기적 추적 결과:

진임건(Im-Geon Jin),강문호(Moon-Ho Kang),황종민(Jong-Min Hwang),정해석(Hae-Seok Jeong),이의룡(Ui-Lyoung Lee),명훈(Hoon Myung),황순정(Soon-Jung Hwang),최진영(Jin-Young Choi),이종호(Jong-Ho Lee),정필훈(Pill-Hoon Choung),김명진(Myung-J 대한구강악안면외과학회 2007 대한구강악안면외과학회지 Vol.33 No.3

Abscesses are common in the oral and maxillofacial area. However, secondary thrombosis of the internal jugular vein accompanying the primary abscess is rare. In 1936, Andre Lemeierre studied 20 patients who showed an initial oropharyngeal infection, septicemia, internal jugular vein thrombosis, and secondary spread of the infection, and after then this condition Lemierre syndrome. Clinically, these patients present with tonsilitis lasting several days, continuous fever, and cervical pain. In the past, ligation and excision of the internal jugular vein was often performed. Current therapeutic modality for this condition is appropriate antibiotic prescription and surgical drainage of abscess. This case report presents a patient who showed symptoms of Lemierre syndrome, initiated as an oropharyngeal infection then developed thrombosis of the internal jugular vein. This patient was admitted into Seoul National University Dental Hospital. In addition to routine antibiotic therapy, surgical incision and drainage of the infection site was performed. Without ligation or excision, the thrombosed IJV disappeared eventually. As the Lemierre syndrome is not a common disease, this case report and review of the literature would be useful regarding a treatment of patients with Lemierre syndrome.

인회석 박막 피복 도관과 Brain-derived neurotrophic factor(BDNF) 유전자 이입 슈반세포를 이용한 백서 좌골신경 재생에 관한 연구

최원재(Won-Jae Choi),안강민(Kang-Min Ahn),황순정(Soon-Jeong Hwang),정필훈(Pill-Hoon Choung),김명진(Myung-Jin Kim),김남열(Nam-Yeol Kim),유상배(Sang-Bae Yoo),장정원(Jeong-Won Jahng),김현만(Hyun-Man Kim),김중수(Joong-Soo Kim),김윤희(Yun 대한구강악안면외과학회 2005 대한구강악안면외과학회지 Vol.31 No.3

Purpose of Study: Peripheral nerve regeneration depends on neurotrophism of distal nerve stump, recovery potential of neuron, supporting cell like Schwann cell and neurotrophic factors such as BDNF. Peripheral nerve regeneration can be enhanced by the conduit which connects the both sides of transected nerve. The conduit maintains the effects of neurotrophism and BDNF produced by Schwann cells which can be made by gene therapy. In this study, we tried to enhance the peripheral nerve regeneration by using calcium phosphate coated porous conduit and BDNF-Adenovirus infected Schwann cells in sciatic nerve of rats. Materials and Methods: Microporous filter which permits the tissue fluid essential for nerve regeneration and does not permit infiltration of fibroblasts, was made into 2mm diameter and 17mm length conduit. Then it was coated with calcium phosphate to improve the Schwann cell adhesion and survival. The coated filter was evaluated by SEM examination and MTT assay. For effective allogenic Schwann cell culture, dorsal root ganglia of 1-day old rat were extracted and treated with enzyme and antimitotic Ara-C. Human BDNF cDNA was obtained from cDNA library and amplified using PCR. BDNF gene was inserted into adenovirus shuttle vector pAACCMVpARS in which E1 was deleted. We infected the BDNF-Ad into 293 human mammary kidney cell-line and obtained the virus plaque 2 days later. RT-PCR was performed to evaluate the secretion of BDNF in infected Schwann cells. To determine the most optimal m.o.i of BDNF-Ad, we infected the Schwann cells with LacZ adenovirus in 1, 20, 50, 75, 100, 250 m.o.i for 2 hours and stained with 􀝜-galactosidase. Rats(n=24) weighing around 300g were used. Total 14mm sciatic nerve defect was made and connected with calcium phosphate coated conduits. Schwann cells(1x106) or BDNF-Ad infected Schwann cells(1x106) were injected in conduit and only media(MEM) was injected in control group. Twelve weeks after surgery, degree of nerve regeneration was evaluated with gait analysis, electrophysiologic measurements and histomorphometric analysis. Results: 1. Microporous Millipore filter was effective conduit which permitted the adhesion of Schwann cells and inhibited the adhesion of fibroblast. We could enhance the Schwann cell adhesion and survival by coating Millipore filter with calcium phosphate. 2. Schwann cell culture technique using repeated treatment of Ara-C and GDNF was established. The mean number of Schwann cells obtained 1 and 2 weeks after the culture were 1.54±4.0×106 and 9.66±9.6×106. 3. The mRNA of BDNF in BDNF-Ad infected Schwann cells was detected using RT-PCR. In Schwann cell 0.69 μg/μl of DNA was detected and in BDNF-Adenovirus transfected Schwann cell 0.795 μg/μl of DNA was detected. The most effective infection concentration was determined by LacZ Adenovirus and 75 m.o.i was found the most optimal. Conclusion: BDNF-Ad transfected Schwann cells successfully regenerated the 14mm nerve gap which was connected with calcium phosphate coated Millipore filter. The BDNF-Ad group showed better results compared with Schwann cells only group and control group in aspect to sciatic function index, electrophysiologic measurements and histomorphometric analysis.

신생 백서 척수후근절의 슈반세포 배양을 위한 Ara-C 분열억제제의 최적 효과에 대한 연구

김성민(Soung-Min Kim),이종호(Jong-Ho Lee),안강민(Kang-Min Ahn),김남열(Nam-Yeol Kim),성미애(Mi-Ae Sung),황순정(Soon-Jeong Hwang),김지혁(Ji-Hyuck Kim),장정원(Jeong-Won Jahng) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.2

Schwann cell, one of important components of peripheral nervous system, interact with neurons to mutually support the growth and replication of embryonal nerves and to maintain the different functions of adult nerves. The Ara-C, known as an antimitotic agent, have been used to have high effectiveness in eliminating fibroblasts during Schwann cell culture period. This enrichment effect is also known to be cummulative with each successive pulse of Ara-C applied and is due to a progressive loss of fibroblasts. But the cytotoxicity by Ara-C is also cummulative and noticeable over the period. To determine the most effective application time and interval of Ara-C in the Schwann cell culture, we observed the Schwann cell purity and density with the Ara-C treatment in plain and three-dimensional culture from dorsal root ganglion of new born rat. By culturing dispersed dorsal root ganglia, we can repeatedly generate homogenous Schwann cells, and cellular morphology and cell count with mean percentages were evaluated in the plain culture dishes and in the immunostainings of S-100 and GFAP in the three-dimensional culture. The Ara-C treated cultures showed a higher Schwann cell percentage (31.0%±8.09% in P4 group to 65.5%±24.08% in P2 group), compared with that obtained in the abscence of Ara-C (17.6%±6.03%) in the plain culture after 2 weeks. And in the three-dimensional culture, S-100 positive cells increased to 56.22%±0.67% and GFAP positive cells to 66.46%±1.83% in G2 group (p<0.05), higher yield than other groups with Ara-C application. Therefore, we concluded that the Ara-C treatment is effective for the proliferation of Schwann cells contrast to the fibroblasts in vitro culture, and the first application after 24 hours from cell harvesting and subsequent 2 pulse treatment (P2 group in plain culture and G2 group in three-dimensional culture) was more effective than other application protocols.

BDNF 유전자 이입 슈반세포와 PGA 도관을 이용한 백서 좌골신경 재생에 관한 연구

최원재(Won-Jae Choi),안강민(Kang-Min Ahn),고은봉(En-Feng Gao),신영민(Young-Min Shin),김윤태(Yoon-Tae Kim),황순정(Soon-Jeong Hwang),김남열(Nam-Yeol Kim),김명진(Myung-Jin Kim),조승우(Seung-Woo Jo),김병수(Byung-Soo Kim),김윤희(Yun-Hee K 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.6

Purpose : The essential triad for nerve regeneration is nerve conduit, supporting cell and neurotrophic factor. In order to improve the peripheral nerve regeneration, we used polyglycolic acid(PGA) tube and brain-derived neurotrophic factor(BDNF) gene transfected Schwann cells in sciatic nerve defects of SD rat. Materials and methods : Nerve conduits were made with PGA sheet and outer surface was coated with poly(lactic-co-glycolic acid) for mechanical strength and control the resorption rate. The diameter of conduit was 1.8㎜ and the length was 17㎜. Schwann cells were harvested from dorsal root ganglion(DRG) of SD rat aged 1 day. Schwann cells were cultured on the PGA sheet to test the biocompatibility adhesion of Schwann cell. Human BDNF gene was obtained from cDNA library and amplified using PCR. BDNF gene was inserted into E1 deleted region of adenovirus shuttle vector, pAACCMVpARS. BDNF-adenovirus was multiplied in 293 cells and purified. The BDNF-Adenovirus was then infected to the cultured Schwann cells. Left sciatic nerve of SD rat (250g weighing) was exposed and 14㎜ defects were made. After bridging the defect with PGA conduit, culture medium(MEM), Schwann cells or BDNFAdenovirus infected Schwann cells were injected into the lumen of conduit, respectively. 12 weeks after operation, gait analysis for sciatic function index, electrophysiology and histomorphometry was performed. Results : Cultured Schwann cells were well adhered to PGA sheet. Sciatic index of BDNF transfected group was -53.66±13.43 which was the best among three groups. The threshold of compound action potential was between 800 to 1000μA in experimental groups which is about 10 times higher than normal sciatic nerve. Conduction velocity and peak voltage of action potential of BDNF group was the highest among experimental groups. The myelin thickness and axonal density of BDNF group was significantly greater than the other groups. Conclusion : BDNF gene transfected Schwann cells could regenerate the sciatic nerve gap(14㎜) of rat successfully.

하치조신경 및 설신경 손상 평가를 위한 한국인 정상 성인의 하순-이부 및 혀의 감각 조사

이종호,이세영,송승일,이은진,안강민,김성민,명훈,황순정,서병무,최진영,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

In the head and neck area, there are so many sensory nerves, which are sometimes injuried iatrogenically or inadvertently so that involved patients complained of the loss of sensations. In such cases, it is important to judge the degree of injuries and regeneration of nerve for better diagnosis and treatment. Seddon and Sunderland's classification, which is commomly used, is focused on histological change and nerve conduction. As times goes by, it is difficult to access patient's sensory disturbance by this method. Until now, so many methods such as contract threshold, direction, two-point discrimination, pin prick, thermal discrimination and current perception threshold have been introduced for sensory evaluation. However, there hasn't been enough information regarding each methodology nor integrated standard methodology for the measurement. the purpose of this study is to get Korean adult normative sensory values of lower lip,chin and tongue using modified methods of contact thershold, ditection, two point discrimination, pin prick, thermal discrimination and assess degree of regeneration of sensory nerve damage.