MEMS 기술을 이용한 미소 리블렛 필름 제작 및 항력 감소에의 응용

한만희,허정기,이상준,이승섭,Han, Man-Hee,Huh, Jeong-Ki,Lee, Sang-Joon,Lee, Seung-Seop 대한기계학회 2002 大韓機械學會論文集B Vol.26 No.7

This paper presents the fabrication method of a micro-riblet film (MRF) using MEMS technology and the experimental results of the drag reduction of an airfoil with MRFs. Riblets having grooved surface in the streamwise direction has been proven as an effective passive control technique of the drag reduction. A V-grooved pattern on (100) silicon wafer is etched with anisotropic bulk micromachining. The MRF is completed by replicating the V-grooved pattern with polydimethylsiloxane (PDMS). Experiments were performed by measuring a velocity field behind the trailing edge of a NACA 0012 airfoil with and without MRFs in a closed-type subsonic wind tunnel using particle image velocimetry (PlV) technique. The MRF provides about 3.8 % drag reduction compared to the drag on a smooth airfoil when the freestream velocity of wind tunnel is 3.3 m/s.

융복합과 건설 산업의 발전

한만희(Man-Hee Han) 대한토목학회 2014 대한토목학회지 Vol.62 No.6

한국의 토지공급관련 정책변화가 주택시장에 미치는 영향분석

한만희(Han, Man Hee),이용범(Lee, Yong Bum) 한국지역개발학회 2021 韓國地域開發學會誌 Vol.33 No.1

This paper aims to examine what extent government policy measures related to land have influenced on the stabilization of housing prices in Korea. For the purpose, first, a qualitative analysis on the changes of land policy measures in the mid-1990s and mid-2000s and their implications for the stability of land and housing market in Korea was carried out. Then a quantitative analysis mobilizing multiple-regression and correlation analysis with time series data representing internal factors of housing market led by land supply, demographic and household factors and macro-economic factors was conducted. The integration of these analyses was thought to provide informations to figure out the factors which have significant influence on the changes of housing prices. The result of analyses showed that, firstly, the completion of legal and institutional systems related to land supply in the mid-1990s has contributed to the housing price stability and, secondly, since then the influence of demographic and macro-economic factors has increased instead of the massive supply of lands in new towns, etc. in stabilizing housing prices. This result implies that specified strategies are necessary for the balance between the housings supplied in newly developed residential sites and those in redevelopment and reconstruction sites inside of cities.

膵臟 諸疾患 51例에 對한 臨床的 考察

韓萬熙(M.H. Han),金久雄(K.W. Kim),孫鍾夏(J.H. Son),李思泰(U.T. Lee) 대한외과학회 1970 Annals of Surgical Treatment and Research Vol.12 No.5

유한요소해석과 실험을 통한 반도체칩의 변형예측

임재혁(Jae Hyuk Lim),한만희(Man-Hee Han),이준연(Jun-Youn Lee),박정순(Jeong Soon Park),엄윤용(Youn Young Earmme),임세영(Seyoung Im) 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.11

Prediction of warpage and residual stress in semiconductor chip devices play an important role in chip design. However, there are a few uncertainties in warpage prediction due to unknown patterning material properties, and moisture effect on polymer film. To estimate patterning material properties, we adopt a composite plate analysis and experimental techniques. and measure the warpage of chip after drying at about 250℃ for 30min to remove moisture. In 100㎛, 80㎛ chip cases, finite element analysis result shows a good agreement with measured values, but for 50㎛ and 60㎛ chip cases, there exist a substantial deviation from the measured values due to local deformation from imperfection and defects inherently embedded in the patterning layer and nonuniform bonding between PIcoating and silicon.

토주실험에서 동물용 의약품의 이동 특성

황선영 ( Sun Young Hwang ),한만희 ( Man Hye Han ),조재영 ( Jae Young Cho ) 한국응용생명화학회 2012 Journal of Applied Biological Chemistry (J. Appl. Vol.55 No.4

Veterinary antibiotics can enter the soil ecosystem and then may be transported into groundwater via leaching process. The main aim of this study is to investigate the distribution and mobility of tetracycline, amoxicillin and sulfathiazole in soil. The adsorption of veterinary antibiotics were applied to the Freundlich adsorption isotherms. Adsorption coefficient (KF) was indicated oxytetracycline > amoxicillin > sulfathiazole. Oxytetracycline concentration was highly detected in soil than in leachate. It is assumed that oxytetracycline was strongly absorbed by divalent cations such as Ca2+ in soil. However, amoxicillin and sulfathiazole were shown higher mobility due to the lower distribution coefficient.

EGF와 IGF-I의 첨가배양이 돼지 미성숙 난포란의 체외성숙과 배발달에 미치는 영향

백준종(Jun-Jong Baek),한만희(Man-Hye Han),박병권(Byung-Kwon Park),서길웅(Kil-Woog Seo),이규승(Kyu-Seung Lee) 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.1

본 연구는 돼지 난포란의 체외배양액과 배발달 배양액에 성장인자인 EGF와 IGF-Ⅰ을 각각 0, 1, 5 및 10 ng/㎖ 첨가배양함으로서 돼지 난포란의 체외성숙과 체외배발달에 미치는 영향을 구명하고자 실시하였다. 본 연구에서 얻어진 결과를 요약하면 다음과 같다. 1. 돼지 난포란을 체외성숙배양액인 NCSU-23 배양액에 EGF와 IGF-Ⅰ을 각각 0, 1, 5 및 10 ng/㎖ 첨가배양하여 성숙을 유기한 다음, 체외수정을 실시한 결과, 모든 처리구에서 핵성숙률, 정자침투율, 웅성전핵형성률, 다정자 침입률 및 평균침입정자수에서 유의적인 차이가 인정되지 않았다. 2. 체외수정을 실시한 후 , 배발달배양액인 NCSU-23에 7일간 배양한 결과, 배반포형성률은 EGF첨가군이 각각 11.2±1.5%, 15.0±0.8%, 16.8±2.8% 및 21.4±2.0%로서 10 ng/㎖의 첨가군이 유의적(P<0.05)으로 높은 결과를 나타냈으며, IGF-Ⅰ첨가군도 10.7±1.4%, 12.8±2.0%, 16.0±2.5% 및 21.9±2.4%로서 10 ng/㎖의 첨가군이 유의적으로 높은 결과를 나타냈다. 또한, 총세포수에 있어서도 EGF첨가군이 22.8±3.7개, 25.7±5.5개, 26.0±4.2개 및 35.1±4.7개, IGF-Ⅰ첨가군은 21.5±3.7개, 25.2±2.8개, 26.2±2.9개 및 33.2±3.6개로서 각각 10 ng/㎖ 첨가군이 유의적(P<0.05)으로 높은 결과를 나타냈다. 3. 돼지 난포란을 체외성숙 기본배양액인 함유된 NCSU-23 배양액에 44시간동안 체외성숙을 유기한 다음, 체외 수정용배양액인 mTBM에 정자와 같이 6시간동안 공배양함으로서 체외수정을 유기한 후, 배발달배양액인 NCSU-23에 EGF와 IGF-Ⅰ을 각각 0, 1, 5 및 10 ng/㎖ 첨가하여 7일간 배양한 결과, 배반포기 도달률은 EGF첨가군에서 각각 14.0±1.7개, 16.2±1.4개, 16.9±1.2개, 23.1±1.6개로서 10 ng/㎖ 첨가군이 유의적으로 높은결과를 나타냈고, IGF-Ⅰ첨가군도 각각 13.6±1.7개, 15.7±4.5개, 16.0±0.2개 및 25.0±0.8개로 10ng/㎖군이 유의적(P<0.05)으로 높은 결과를 나타냈으며, 총세포수에 있어서는 EGF첨가군이 각각 21.8±2.9개, 25.2±2.8개, 39.7±2.7개 및 46.2±3.6개로 10 ng/㎖첨가군이 유의적으로 높은 결과를 나타냈고, IGF-Ⅰ첨가군도 20.7±2.9개, 26.2±2.9개, 24.6±2.4개 및 46.1±3.5개로 10 ng/㎖ 첨가군이 유의적(P<0.05)으로 높은 결과를 나타냈다. 이상의 결과를 종합해 볼 때, EGF와 IGF-Ⅰ은 돼지 난포란의 체외성숙과 배발달과정에 영향을 미치며 특히, 10 ng/㎖의 농도에서 효과적인 것으로 조사되었다. The present study was carried out to examine the effect of EGF and IGF-Ⅰ in vitro maturation (IVM) of porcine oocytes and development of porcine IVM/IVF embryos. The results were summarized as follows : 1. The rates of nuclear maturation, penetrated oocytes, pronuclear formation, polyspermic oocytes and mean numbers of the penetrated sperm were not different in NCSU-23 maturation medium with 0, 1, 5 and 10 ng/㎖ EGF and IGF-Ⅰ (P>0.05). 2. The rates of blastocyst formation at day 7 after in vitro fertilization in 0, 1, 5 and 10 ng/㎖ EGF groups were 11.2±1.5%, 15.0±8.3%, 16.8±2.8% and 21.4±2.0%, also 0, 1, 5 and 10 ng/㎖ IGF-Ⅰ groups were 11.2±1.5%, 15.0±8.3%, 16.8±2.8% and 21.4±2.0%, respectively. In the total cells case, EGF groups were 22.8±3.7, 25.7±5.5, 26.0±4.2 and 35.1±4.7, also IGF-Ⅰ groups were 21.5±3.7, 25.2±2.8, 26.2±2.9 and 33.2±3.6, respectively. Both 10 ng/㎖ EGF group and 10 ng/㎖ IGF-Ⅰ group were significantly higher than those of other treatment groups (P<0.05). 3. The rates of blastocyst formation at day 7 in the NCSU23 culture medium of porcine IVF-produced embryos with 0, 1, 5, and 10 ng/㎖ EGF groups were 14.0±1.7%, 16.2±1.4%, 16.9±1.2% and 23.1±1.6%, also 0, 1, 5, 10 ng/㎖ IGF-Ⅰ groups were 13.6±1.7, 15.7±4.5, 16.0±0.2 and 25.0±0.8, respectively. And in the total cells case, EGF grups were 21.8±2.9, 25.2±2.8, 39.7±2.7 and 46.2±3.6, also IGF-Ⅰ groups were 20.7±2.9, 26.2±2.9, 24.6±2.4 and 46.1±3.5, respectively. Both 10 ng/㎖ EGF group and 10 ng/㎖ IGF-Ⅰ group were significantly higher than those of any other treatment groups (P<0.05). In conclusion, these results suggested that the addition of 10 ng/㎖ EGF and IGF-Ⅰ were effective on the blastocyst formation and total cells of blastocysts.

조세담보부재원(TIF)을 활용한 도시재생사업 재원조달 효과에 관한 연구

김회대(Kim, Hoe-Dae),한만희(Han, Man-Hee),박준(Park, Joon) 대한국토·도시계획학회 2017 國土計劃 Vol.52 No.4

The purpose of this study is to find out a way of financing an urban regeneration project using Tax Increment Financing(TIF) scheme. With a case of an urban regeneration project in Cheonan city by the 「Special Act on Promotion of and Support for Urban Regeneration」, this study simulates potential tax increment after the project especially focusing on property related taxes. As a result of the analysis, it was predicted that it would be possible to procure funding resources with TIF corresponding to 14.1~17.8% of the infrastructure cost of the Urban Regeneration Revitalization Area. It goes up to 47.3% at the maximum depending on the project contents.

마이크로 리블렛을 이용한 원주 주위 유동의 제어

임희창(Hee Chang Lim),한만희(ManHee Han),이상준(Sang Joon Lee),이승섭(Seung S. Lee) 대한기계학회 2002 대한기계학회 기타 간행물 Vol.2002 No.11

TGF- ${\beta}$ 첨가가 한우 난포란의 체외성숙에 미치는 영향

최선호,이혜현,연성흠,한만희,김현종,조상래,우제석,백광수,류일선,손동수,Choi, Sun-Ho,Lee, Hye-Hyun,Yeon, Seong-Heum,Han, Man-Hye,Kim, Hyun-Jong,Cho, Sang-Rae,Woo, Jae-Seok,Baek, Kwang-Soo,Ryu, Il-Sun,Son, Dong-Soo 한국발생생물학회 2004 발생과 생식 Vol.8 No.2

소 체외성숙시 난포란에 영향을 주는 과립막세포와 난자의 핵성숙을 촉진하는 물질이 확인되지 않은 혈청내의 물질 뿐만 아니라 호르몬이나 생리활성인자 등에 의해 촉진됨이 밝혀졌다. 이에 따라 체외성숙 및 체외발달에 사용되는 배양액의 조성도 복합배양액에서 단순배양액으로 전환을 시도하고 있으며, 체내의 조건에 보다 더 접근하고자 하는 시도들이 수행되고있다. 본 연구는 한우 난포란의 체외성숙율 및 체외수정 후 배발달율을 향상시키기 위하여 TGF-${\beta}$의 첨가가 미치는 영향에 대하여 조사하였다. 한우 난포란의 체외성숙시 TGF-${\beta}$ 0.1, 1. 10ng/ml를 첨가하였을 때 24시간에 MetaphaseⅡ 도달율은 95.8%, 95.8%, 100%를 나타내었으며, 농도간의 유의적인 차이는 없었다. TGF-${\beta}$로 체외성숙된 난포란을 체외수정 후 TGF-${\beta}$가 체외성숙 배양액을 동일하게 체외발달을 유도하였으나, 0~0.8%의 배반포율을 보였으며, TGF-${\beta}$로 체외성숙된 난포란을 체외수정 후 TCM 199_10% FBS, 0.8% BSA, 0.1% PVA에 배양한 결과 12.4%, 12.8%, 8.5%의 배반포 발달율을 보였고, 무혈청 배양액인 IVMD, IVD에 배양한 결과 38.4%, 34.8%의 배반포 발달율을 보였으며, 유의적인 차이를 나타냈다(P<0.005). 결론적으로 TGF-${\beta}$는 한우 난포란의 체외성숙시 상당히 유용한 물질이나, 체외발달에는 만족할 수 없어, 이외의 생리활성 인자들간의 상호관계에 대하여 더 많은 요구가 요구된다. It is well known that unidentified factors in sera, hormones and growth factors promote the proliferation of granulosa cells and nuclear maturation of bovine COCs in vitro. Attemps had been developed the simple composition of culture media and similar system to in vivo conditions has been applied. In the present study, we investigated the effect of TGF-${\beta}$ on in vitro maturation and in vitro development of Hanwoo COCs. When the COCs were matured in TCM 199 containing 0.1, 1 or 10 ng/ml TGF-${\beta}$ for 24 hrs, metaphaseⅡ of COCs were obtained 95.8%, 100% of matured COCs, respectively and there were no differences among the concentrations of TGF-${\beta}$. Matured COCs with TGF-${\beta}$ cultured in maturation medium after in vitro fertilization, developmental rate to blastocyst were 0~0.8%. Matured COCs with TGF-${\beta}$ were cultured in TCM 199+10% FBS, 0.8% BSA, 0.1% PVA, blastocyst formation were showed in 12.4%, 12.8%, 8.5% of those and cultured in IVMD or IVD without serum were 38.4%, 34.8%, respectively. There were significant differences among the media (P<0.05). TGF-${\beta}$ is available for i vitro maturation of bovine COCs, but further investigation would be need for finding the synergistic autocrine/paracrine fashion of other growth factors in early bovine development.