황련해독탕 투여 후 Vancomycin-resistant Enterococcus 집락이 해제된 외상성 지주막하출혈 및 경막하혈종 환자 증례보고 1례

채한나,이지은,심상송,신선호,신용진 대한한방내과학회 2020 大韓韓方內科學會誌 Vol.41 No.3

This study aimed to investigate the effect of Hwanglyeonhaedok-tang on the clearance of vancomycin-resistant Enterococcus (VRE) colonization in a patient with traumatic subarachnoid hemorrhage and subdural hematoma. A 73-year-old man who was diagnosed with traumatic subarachnoid hemorrhage and subdural hematoma with isolation of VRE colonization was administered Hwanglyeonhaedok-tang and followed up with a rectal swab VRE culture every week. After treatment with Hwanglyeonhaedok-tang, VRE colonization was no longer detected. This case report proved that Hwanglyeonhaedok-tang could be an effective treatment for clearance of VRE colonization in a patient with traumatic subarachnoid hemorrhage and subdural hematoma.

계지가부자탕이 근골격계 질환을 주소로 내원한 환자들의 간 기능에 미치는 영향

채한나,이준영,심상송,신선호,신용진 대한한방내과학회 2019 大韓韓方內科學會誌 Vol.40 No.6

Objectives: This study aimed to investigate the effects of Gyejigabuja-tang on liver function in patients with musculoskeletal disease. Methods: This research compared and analyzed data from liver function tests on patients who were treated with Gyejigabuja-tang during 17.98±1.78 days. Results: No significant effects appeared in the liver function of patients who were treated with Gyejigabuja-tang. Conclusions: This study suggests that Gyejigabuja-tang, which includes Aconiti Radix Lateralis Preparata, known as a toxic herb, may be used without causing significant liver injury if administered correctly as in this study.

XML 암호화 제품을 위한 표준적합성 시험도구 구현

채한나,이광수,Chae Han-Na,Rhee Gwang-Soo 한국정보처리학회 2006 정보처리학회논문지 C : 정보통신,정보보안 Vol.13 No.4

XML 암호화는 주로 웹 콘텐츠를 위한 기밀성 서비스 제공에 사용되는데, 물론 응용 영역이 반드시 웹 콘텐츠로만 제한되는 것은 아니다. XML 암호화는 데이터 파일 단위로 적용될 수도 있지만, 주로 XML 문서에 부분적으로 적용되면서 다양한 암호화 범위를 지원한다. 이러한 특성으로 인해 XML 암호화는 여러 웹 애플리케이션에서 SSL/TLS, IPsec, PGP, S/MIME 등의 여타 기밀성 프로토콜보다 효율적인 수단이 될 수 있다. XML 암호화의 성공적 정착을 위해서는 구현 제품들 사이의 상호운용성이 필수적인데, 이를 위해서는 제품들이 XML 암호화 표준을 정확히 구현해야 한다. 표준적합성 시험에서는 제품들이 관련 표준을 정확히 구현하였는지를 시험한다. 본 논문에서는 XML 암호화 제품을 위한 표준적합성 시험 방법을 제시하고 구현한다. 이를 위해 먼저 W3C에서 개발된 XML 암호화 표준을 먼저 살펴보고, 적합성 시험을 위한 항목들을 도출한다. 그런 다음 시험 방법을 제안하는데, 여기에서는 암호화 기능과 복호화 기능을 분리하여 시험하는 방식을 취한다. 또한 제안된 방법을 GUI 기반의 시험 도구로 구현하여 시험 결과를 제시한다. XML encryption is to provide confidentiality service, though not limited to, for web contents. XML encryption can be applied to entire data files as opaque objects, or more frequently to various parts of XML documents, supporting various encryption granularity. It is this characteristic that makes XML encryption a more efficient alternative for data confidentiality in various web applications than is possible with SSL/TLS, IPsec, PGP, or S/MIME. It is essential for successful deployment of XML encryption to achieve interoperability among the products implementing this technology, which requires the products to implement the XML encryption standards correctly. Conformance testing is to test if products implement the relevant standard correctly. In this paper we present a conformance testing method for XML encryption products and implement it. We will first look at XML encryption standards developed by W3C, and extract test criteria. Then we propose a testing method in which the encryption capability and the decryption capability of a product are tested separately. The proposed methody is actually implemented as a GUI-based testing tool and some test results are presented.

향사평위산의 항염증 효과 및 이상지질혈증 개선 작용에 대한 연구

채한나,천세은,신용진,Han-nah Chae,Se-eun Chun,Yong-jeen Shin 대한한방내과학회 2023 大韓韓方內科學會誌 Vol.44 No.3

Objectives: This study aims to investigate the anti-inflammatory effect and improvement of dyslipidemia on Hyangsapyeongwi-san. Methods: In this study, HUVEC cells were cultured and treated with Hyangsapyeongwi-san to measure intracellular KLF2, eNOS, MCP-1, ICAM-1, and VCAM-1 gene expression levels related to anti-inflammation. The weight of experimental animals administered with Hyangsapyeongwi-san was measured, blood samples were biochemically analyzed, and liver tissues were reviewed to research histological changes. Results: Gene expression levels in the cells treated with Hyangsapyeongwi-san generally showed a meaningful anti-inflammatory effect. The body weight of the experimental animals decreased, and total cholesterol, triglyceride, and LDL-cholesterol in the blood generally declined while HDL-cholesterol tended to increase. Fat accumulation between hepatocytes was also reduced after the administration of Hyangsapyeongwi-san. Conclusions: This study confirmed that Hyangsapyeongwi-san has the effect of suppressing vascular inflammatory responses through the regulation of genes involved in the vascular inflammatory process and improving dyslipidemia through the reduction of blood lipids and weight loss.

XML 암호화 제품을 위한 표준 적합성 시험 방법론 연구

채한나(Hanna Chae),이광수(Gwangsoo Rhee) 한국정보과학회 2005 한국정보과학회 학술발표논문집 Vol.32 No.1

국내의 한 인터넷 경매업체는 “대한민국 국민 5명 중 한명은 이미 자신들의 경매를 경험해 보았다.”라고 광고할 정도로 웹 기반의 전자상거래는 이미 우리의 일상생활에 깊이 파고든 상태이며, 이제는 단순한 웹상의 전자상거래 뿐이아닌 웹 서비스 개념의 시대가 현실화 되고 있는 시점이다. 이러한 흐름 속에서 XML은 데이터만을 따로 표현할 수 있다는 특성에 의하여 업계의 표준으로 떠올랐으며, 자연스럽게 이와 더불어 XML의 보안기능은 주목을 받고 있다. XML 전자서명, XML 암호화, XML 키 관리 명세는 주요한 XML 보안기술로서 표준화가 진행되어 많은 부분 완료되었다. 이에 따라 표준을 구현한 제품들이 출시되어 상용화되고 있다. 이러한 제품들은 표준에 적합하도록 개발되어야만 제품의 목적인 안정성과 각 제품들 간의 상호운용성에 있어서의 신뢰도를 검증받을 수 있다. 이에 본 논문에서는 XML 암호화에 대한 표준 적합성 시험 방법을 제시하고 시험도구를 구현하였다.

형방지황탕가미로 치료한 만성 난치성 설사 치험 3례에 대한 임상적 고찰

이준영,채한나,문연주,이윤승,곽시라,문구,백동기 대한한방내과학회 2019 大韓韓方內科學會誌 Vol.40 No.5

Objective: This study reports the effect of Hyungbangjihwang-tang-gami as a treatment for Soyang-in patients with chronic diarrhea. Methods: We treated three male patients with chronic diarrhea who did not improve after taking herbal medicine, as determined by zang-fu (organ) pattern diagnosis. After changing our approach to a Sasang constitution, we prescribed Hyungbangjihwang-tang-gami and assessed the effect by the frequency or form of defecation. Results: The patients' complaints worsened when they were administered a herbal medicine unsuited to their Soyang constitutions, which caused an exuberance of Yang. Changing the herbal medicine to Hyungbangjihwang-tang-gami improved their symptoms. Conclusions: This study suggested that Soyang-in patients may have side effects when administered unsuitable herbs, even if they were diagnosed using zang-fu (organ) pattern diagnosis. When we treat patients, we have to consider their Sasang constitution, as well as the zang-fu (organ) pattern diagnosis.

완하제를 장기간 복용한 만성 변비 환자를 한약으로 치료한 치험 2례

이준영,문연주,채한나,문구,권영미,백동기 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.5

Objectives: This study reports the effect of herbal medicine to replace laxatives for patients with chronic constipation. Methods: The patients who took laxatives due to long-term constipation were prescribed herbal medicine instead. We assessed whether they could defecate without laxatives and if their bowel habits improved using only herbal medicine. Results: The use of herbal medicine instead of laxatives improved patients' defecation and reduced symptoms such as hard stool, difficulty during defecation, and sensation of incomplete evacuation. Conclusions: Through two cases, we found that herbal medicine is effective for patients who are dissatisfied with laxatives.

한의치료로 호전되었던 사지마비, 운동실조, 인지저하를 호소하는 베르니케 뇌병증 환자 증례보고 1례

심상송,이현승,안재윤,채한나,윤종민,문병순 대한한방내과학회 2020 大韓韓方內科學會誌 Vol.41 No.5

Background: This study is a report on a case of a Wernicke’s encephalopathy with quadriplegia, ataxia, and impaired cognition, whose condition was improved by Korean medicine treatment. Case report: A 51-year-old man diagnosed with Wernicke’s encephalopathy was treated with acupuncture, Banhabakchulchunma-tang mixed with Ondam-tang-gami (半夏白朮天麻湯合溫膽湯加味), cupping, moxibustion, and rehabilitation. Clinical symptoms were measured with the Manual Muscle Test (MMT), Berg Balance Scale (BBS), Korean Mini Mental Status Exam (K-MMSE), Functional Independence Measure (FIM), Modified Barthel Index (MBI), and a numeric rating scale (NRS). After 22 days of treatment, his clinical symptoms showed improvement. The motor function improved (MMT Rt. side Gr. 4+G/4+G, Lt. side Gr. 4G/4+G → Rt. side Gr. 5-N/4+G, Lt. side Gr. 5-N/4+G), Ataxia was relieved (BBS 3→33), cognition improved (K-MMSE 15→27), ADL scores showed improvement (FIM 58→90, MBI 40→75), and the NRS score decreased for headache (3→0). Conclusion: Korean medicine treatment could be effective in the treatment of patients with Wernicke’s encephalopathy.

수면장애와 보행장애를 호소하는 올리브교소뇌위축증 환자 증례보고 1례

이수영,김두리,이현승,채한나,윤종민,문병순,Lee, Su-yeong,Kim, Du-ri,Lee, Hyun-seung,Chae, Han-nah,Yun, Jong-min,Moon, Byung-soon 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4

This case report describes a patient with olivopontocerebellar atrophy accompanied by sleep disorder and gait disturbance whose condition was improved by treatment with Korean medicine. The 61-year-old woman, who was diagnosed with olivopontocerebellar atrophy (Multiple Systemic Atrophy-Cerebellum), was admitted to hospital twice and treated with Korean medicine (acupuncture and herbal medicine) and rehabilitation. The Korean medicine was Gwibiondam-tang-gami and Jaeumgeonbi-tang-gami. Clinical symptoms were assessed by the Modified Bathel index, functional independent measurement, Berg balance scale, and Unified Multiple System Atrophy rating scale. A brain MRI at the one-year follow up after onset showed similar progress but clinical symptoms were improved after treatment, and the evaluation index score increased. Multiple system atrophy, a type of degenerative neurological disease, has no targeted treatment. In this situation, although this report describes a single case, Korean medicine treatment could provide a meaningful improvement in the sleep disturbance and gait disorder symptoms of patients with olivopontocerebellar atrophy.

발병기간 1년 이내 뇌졸중 환자의 핵심 감정척도 단축형을활용한 정서적 특성 연구

손성은,이가원,이나현,채한나,정문주,강형원,류영수 대한한방신경정신과학회 2019 동의신경정신과학회지 Vol.30 No.3

Objectives: This study was conducted to investigate the emotional characteristics of the patients within one year after stroke using the Core Seven Emotions Inventory-Short Form. Methods: It analyzed the medical records of 39 stroke patients who had visited W University hospital and completed the Core Seven-Emotions Inventory-Short Form (CSEI-S), the K-MBI, the PWI-SF, and the HADS. Patients data were analyzed by descriptive analysis, frequency analysis, the Mann-Whitney U test, and the nonparametric test of the CSEI according to the period of stroke onset in patients and Spearman’s correlation analysis using the SPSS (Statistical Package for the Social Science, IBM, United States of America) Version 23.0. Results: First, in the case of depression, all subjects were in the danger group, although more than half of the joy, anger, thinking, sadness and fear were included in the normal group in the shortening of the key seven-point scale. Secondly, in measuring the social and psychological stress and hospital anxiety and depression, social and psychological stress were indicated to be a potential danger group, while anxiety and depression were shown to be a healthy group. Thirdly, the emotional characteristics were explored according to the sub-factor of the shortening of the key seven-figure emotional scale after being classified within two months, between two and six months and over six months depending on the duration of the outbreak. As a result, statistically significant, Joy was the highest score over six months and the lowest score between two and six months. On the other hand, the case of depression was depicted to be significantly lower at over six months, and was highest between two and six months. Finally, the correlations on each scale were statistically significant. Conclusions: This study provided that the CSEI-S can be used to simply to measure the emotions of patients according to the period of the onset of stroke in the clinical scene.