조현병 환자와 양극성 I형 장애 환자에서 인지조절 결함의 비교

진보현,윤혜림,배민재,원승희 대한신경정신의학회 2020 신경정신의학 Vol.59 No.3

Objectives Cognitive control is an adaptive behavior that requires goal-maintaining ability in response to a dynamically changing environment. This study examined the differences and profiles of cognitive control deficits to determine if cognitive control could be a possible candidate as a common pathophysiologic marker of schizophrenia and bipolar disorder. Methods Three groups were included in this study: remitted schizophrenia patients (n=56), patients in euthymic states of bipolar I disorder (n=52), and healthy control (n=57), who were matched on sex, age, years of education. The Continuous Performance Test of the AX version (AXCPT) was used to evaluate the cognitive control function. Intelligence, psychopathology, and psychomotor speed were also examined. The degree of cognitive control deficits was assessed by the commission error rates, correct response times, and the d’ values. Results Both patient groups performed worse in the AX and BX trials than the healthy control. Both patient groups showed a delayed response in all trials than the healthy control. The d’ value was the highest in the healthy control group, but there were no significant differences between the two patient groups. The profile of defects in the two patient groups was the same, with the BX trial having the highest defects in the order of the AX, BY, and AY trials. Conclusion These findings indicate that cognitive control is impaired in patients with schizophrenia and bipolar I disorder. Impairments in cognitive control are likely to be a possible shared pathophysiological marker for both disorders.

유병률, 공존 질환, 증상에 기초한 경계선 인격 장애, 외상후 스트레스 장애,복합성 외상후 스트레스 장애의 임상 양상 구분

진보현,정운선 한국정신분석학회 2023 精神分析 (Psychoanalysis) Vol.34 No.2

It is important for the therapist to differentiate between the symptoms of childhood trauma-related disorders, such as post-traumatic stress disorder (PTSD), complex post-traumatic stress disorder (cPTSD), and borderline personality disorder (BPD), and to evaluate whether these disorders coexist. Instead of the diagnosis of BPD with general stigma, the diagnosis of cPTSD without BPD has less stigma with a more accurate evaluation and treatment plan for patients. The relationship between PTSD, cPTSD/disturbance of self-organization (DSO), and BPD was evaluated in terms of prevalence, comorbidities, and clinical features. The comorbidity of BPD at diagnosis of cPTSD was higher than that of cPTSD at diagnosis of BPD. BPD symptoms tended to appear together with PTSD or cPTSD/DSO symptoms, rather than appearing separately, and in a subgroup with high severity of cPTSD. It suggested that the symptoms were more complex and aggravated during the transition from PTSD to cPTSD/DSO, and then followed by BPD after exposure to trauma. cPTSD/DSO symptoms were found to be distinct from PTSD and BPD symptoms; PTSD being fear-related intrusive memory, avoidance, and hypervigilance, and cPTSD/DSO being emotional numbness and emptiness, impaired self-perception, detachment from relationships, and BPD was characterized by emotional reactivity, impulsivity, emptiness, fear of abandonment, and a fragmented unstable sense of self. cPTSD/DSO was characterized by fear of getting close, avoidance, and unwillingness to make relationships, while BPD was characterized by intense, fleeting relational hostility and alternating excessive enmeshment in relationships. Cases with all BPD, PTSD, cPTSD/DSO symptoms were more strongly associated with accumulated more severe interpersonal trauma from childhood than those with cPTSD/DSO symptoms or PTSD without BPD symptoms.

포장상태지수를 활용한 표면처리공법의 경제적인 적용시기 결정방안 연구

진보현,임상윤,최연우,이상염,박경원 한국도로학회 2016 한국도로학회 학술발표회 논문집 Vol.2016 No.06

1960년대 고속도로의 등장 이후 급격한 산업화와 더불어 국내의 도로연장과 교통량 및 중차량 비중의 증가, 기후변화로 인한 집중호우 및 강설 등의 요인으로 포장파손이 가속화되고 있으며 도로의 관리연장 및 노후화 비중의 급증으로 인한 도로유지관리 비용은 지속적으로 증가하고 있다. 예로 서울시의 경우, 건설 후 20년 이상으로 노후화되어서 도로유지관리 비용은 2020년 이후에는 도로건설비용을 초과할 것 으로 예상되지만 유지관기 예산은 감소추세에 있어 체계적이고 효율적으로 도로관리를 수행하고자 1999 년부터 도로포장관리시스템(PMS: Pavement Management System)을 도입하여 합리적이고 투명하게 도 로포장유지관리 예산편성을 수행하고 있다. 하지만 서울시의 도로포장유지보수 예산은 포장의 상태가 가 장 나쁜 구간을 우선 보수하는 보수전략(Worst First)으로 파손의 정도가 심한 구간에 절삭 후 고온의 아 스팔트 콘크리트를 생산 및 재포장하는 방법 위주로 진행되고 있어 한정된 도로포장 유지보수 예산 하에 서는 증가되는 노후 및 파손된 도로포장의 상태를 일정한 수준으로 유지하기가 점점 어려워지고 있다. 이 러한 문제점을 해결하기 위하여 서울시는 미국, 유럽 등 선진국에서 보편화된 예방적 유지보수공법을 도 입하여 도로가 파손되기 전에 미리 예방하여 포장수명을 연장하여 예산을 절감하고자 노력하고 있다. 이 에 본 연구는 서울시에서 시범적으로 적용한 예방적 유지보수공법의 공용성을 평가하고 경제성분석을 실 시하여 예방적유지보수공법의 도로포장 수명연장효과와 이에 따른 예산절감 효과를 검토하였다. 서울시 에 시험 적용한 예방적 유지보수 공법의 공용성 및 경제성을 평가한 결과 도로포장의 상태에 적합한 공법 을 적용하면 도로포장의 공용수명을 효과적으로 연장할 수 있는 것으로 평가되었다. 위의 그림 1과 같이 절삭 덧씌우기 포장을 한경우보다 예방적 유지보수를 활용했을 경우 공용수명이 연 장되는 것을 확인 할 수 있으며 현재 단가로는 경제성 이득을 취할 수 없는 것을 확인하였다. 따라서 본 연구는 예방적유지보수 공법별 공용성에 따른 경제성 확보를 위한 적정단가를 제시하였다.

학대 경험과 인지기능 및 정서조절 어려움 사이의 관련성에 대한 예비 연구

김경민,김민석,진보현,남지현,이상원 대한생물치료정신의학회 2023 생물치료정신의학 Vol.29 No.3

Objectives: This study was conducted to evaluate the relationship among childhood maltreatment, cognitive function and emotion dysregulation in healthy adults who have not been diagnosed with existing mental diseases and do not report clinically significant levels of symptoms. Methods: The participants were 66 healthy young adults aged 20 to 40 recruited from October 2021 to March 2022. Cognitive function, maltreatment experience, emotion dysregulation and depressive symptoms were evaluated. Their association was analyzed using Kendell’s tau coefficient. In addition, multiple linear regression was conducted to explain emotion dysregulation using cognitive measures. Results: As a results of Kendall’s tau coefficient calculation, emotional abuse experience showed a significant negative correlation with cognitive functions such as perceptual reasoning, working memory and processing speed. The degree of difficulty in emotion regulation reported a significant positive correlation with processing speed among cognitive functions. In the multiple linear regression analysis, processing speed among the cognitive function measures might be revealed to be a factor that can affect emotion regulation even after excluding the influence of other measures. Conclusions: The results of this preliminary study suggest that certain maltreatment experiences, such as emotional abuse, can affect cognitive decline, even if there is no clear mental illness, and the cognitive function can be associated with difficulties in emotional control.

항정신병약물로 유발된 고프로락틴혈증을 가진 조현병 환자의 삶의 질

우선진(Seonjin Woo),진보현(Bo-Hyun Jin),원승희(Seunghee Won) 대한생물치료정신의학회 2018 생물치료정신의학 Vol.24 No.3

Objectives:Antipsychotic-induced hyperprolactinemia causes physical symptoms, such as amenorrhea, galactorrhea, gynecomastia, sexual dysfunction, and bone density loss, as well as psychiatric symptoms, such as depression and cognitive impairments. This study aimed to clarify the associations among hyperprolactinemia caused by antipsychotics in patients with schizophrenia, psychiatric pathology, and psychosocial factors. Methods:Ninety-nine patients with schizophrenia in the psychiatry department of a university hospital were registered between 2015 and 2017. All participants were assessed using structured questionnaires to elucidate psychopathology, social function, quality of life, and hyperprolactinemia-related side effects. The standard levels for hyperprolactinemia were 24ng/mL for women and 20ng/mL for men. Results:The average prolactin levels were 73.45±49.37ng/mL in patients with hyperprolactinemia and 9.16±6.42ng/mL in those without hyperprolactinemia. The average prolactin level in women was significantly higher than that in men(p=0.04). Risperidone was most commonly administered in patients with hyperprolactinemia(58.1%, p<0.01), while aripiprazole was most commonly administered in those without hyperprolactinemia(44.7%, p<0.01). Patients with hyperprolactinemia had significantly higher Positive and Negative Syndrome Scale(p=0.03) and Patient Health Questionnaire-9(p=0.05) scores and had significantly lower Social and Occupational Functioning Assessment Scale(p=0.04) and Strauss–Carpenter Levels of Functioning Scale(p=0.03) scores than patients without hyperprolactinemia. There were no significant differences in side effects or quality of life between the two groups. Conclusion:These findings demonstrate that hyperprolactinemia confers negative effects on depression and social function, but does not directly affect the quality of life. These results suggest that patients with schizophrenia who take antipsychotics that increase prolactin or cause side effects of hyperprolactinemia need to be assessed and receive interventions for depression.

양극성 I형 장애 환자와 발병하지 않은 일차 친족에서 인지조절의 비교

윤혜림,우선진,이상원,진보현,우정민,원승희,Yun, Hyerim,Woo, Seonjin,Lee, Sang-Won,Jin, Bo-Hyun,Woo, Jungmin,Won, Seunghee 대한생물정신의학회 2018 생물정신의학 Vol.25 No.1

Objectives This study intended to identify the deficits of cognitive control among patients with bipolar I disorder and their first-degree relatives, and identify the possibility of cognitive control as an endophenotype of bipolar disorder. Methods The study included three groups: euthymic states patients with bipolar I disorder (n = 55), unaffected first-degree relatives of probands with bipolar I disorder (n = 30), and a healthy control group (n = 51), that was matched on age, sex, and years of education. The AX version of the continuous performance test (CPT) was used to examine cognitive control. Error rate, correct response times of each subsets (AX, BX, AY, BY), and d' as an indication of accuracy sensitivity index were calculated. Psychopathology, intelligence, and psychomotor speed were also assessed. Results Patients with bipolar I disorder showed significantly worse error rates in the AX (p = 0.01) and BX (p = 0.02) subsets and d' (p = 0.05) than the others. They also showed more delayed correct response times than the healthy control group and first-degree relatives in all subsets (p < 0.01). But first-degree relatives showed neither high error rates nor delayed correct response times than healthy control group. Conclusions These findings suggest that cognitive control is impaired in bipolar I disorder but less likely to be an endophynotype of bipolar I disorder.

보안성 향상을 위한 IoT 서비스 시스템 구현 및 평가

김진보(Jin-bo Kim),김미선(Mi-sun Kim),서재현(Jae-hyun Seo) 한국정보보호학회 2017 정보보호학회논문지 Vol.27 No.2

사물인터넷은 다양한 사물들로부터 발생되는 정보를 수집·공유·분석하여 사람들에게 유용한 정보 서비스를 제공하는 것을 의미한다. 본 논문은 사물인터넷 환경에서 발생하는 서비스 접근제어, 서비스 보안 기술 그리고 ID 관리 기술에 대한 서비스 영역에서의 보안 안전성을 향상시키는 방안을 제시한다. 서비스 보안의 안전성 향상을 위해 공개키 기반의 C&C(Certificate and Capability) 서비스 토큰 인증서를 설계하고 발급할 수 있는 서비스를 구현하였다. 또한 노드 디바이스로부터 수집된 데이터를 기반으로 리소스 서비스의 생성 시 이를 효율적으로 관리하고자 LCRS(Left Child-Right Sibling) 리소스 모델관리 방안과 서비스에 대한 접근제어를 위해 리소스 서비스 URI 보안 관리하는 IoT 서비스 시스템을 구현하였다. Internet of Things includes the whole process of collected information generated from a variety of objects, as well as analyzing and sharing it, and providing useful information services to people. This study seeks ways to improve security and safety in the areas of service security technology, ID management technology and service access control, all of which take place in the IoT environment. We have implemented the services that can design and issue C&C (Certificate and Capability) service token authentication, which is based on a public key, to improve the service security. In addition, we suggest LCRS (Left Child-Right Sibling) resource model management for the efficient control of resources when generating the resource services from the data collected from node devices. We also implemented an IoT services platform to manage URL security of the resource services and perform access control for services.

사물인터넷 서비스 접근제어를 위한 리소스 서비스 관리 모델 구현

김진보(Jin-Bo Kim),김미선(Mi-Sun Kim),서재현(Jae-Hyun Seo) 한국스마트미디어학회 2016 스마트미디어저널 Vol.5 No.3

사물인터넷 기술을 이용한 서비스 형태는 셀 수 없이 많으며, 현재도 여러 기관에서 다양한 서비스를 제공하기 위해 새로운 기술이나 프로토콜을 만들어 내고 있다. 본 논문은 사물인터넷 서비스 접근제어를 위한 시스템에서 효율적인 서비스 제공을 위한 리소스 서비스 모델을 설계하고 구현한다. 사용자가 접근하고자 하는 리소스 서비스를 LCRS(Left Child-Right Sibling) 트리를 이용하여 모델링하고, 리소스 서비스 토큰을 이용하여 서비스에 대한 접근 제어를 수행할 수 있다. Many countless services form using the Internet technology of things, in order to provide a variety of services in the current also many institutions, have created a new technology and protocols. In this paper, we design the resource service model for the efficient service provided by the system for controlling access to the Internet services of the things, to implement. The resources of the service that the user tries to access modeled using LCRS (Left Child-Right Sibling) tree, by utilizing the service token resource, it is possible to perform access control to services.

CapSG를 이용한 IoT 서비스 접근제어 플랫폼

김진보 ( Jin Bo Kim ),장데레사 ( Deresa Jang ),김미선 ( Mi Sun Kim ),서재현 ( Jae Hyun Seo ) 한국정보처리학회 2015 정보처리학회논문지. 소프트웨어 및 데이터 공학 Vol.4 No.9

There is great need for efficient user rights management method to provide a flexible service on variety protocols, domains, applications of IoT environments. In this paper, we propose a IoT service platform with CapSG to provide efficient access control for IoT various services of the environment. CapSG uses a token including authentication and access rights to perform authentication and access control service entity providing services. In addition, the generated token for service management, delegation, revocation, and provides a function such as denied. Also, it provides functions such as generation, delegation, disposal and rejection for service token management. In this paper, it provides the flexibility and efficiency of the access control for various services require of the IoT because of it is available to access control specific domain service by using the token group for each domain and is designed to access control using specific service token of tokens group.

웹 2.0과 Ajax 보안 취약점

김미선(Mi-Sun Kim),김진보(Jin-Bo Kim),양형초(Hyoung-Cho Yang),김용민(Yong-Min Kim),서재현(Jae-Hyun Seo) 한국정보과학회 2007 정보과학회지 Vol.25 No.10