양극성 I형 장애 환자와 발병하지 않은 일차 친족에서 인지조절의 비교

윤혜림,우선진,이상원,진보현,우정민,원승희,Yun, Hyerim,Woo, Seonjin,Lee, Sang-Won,Jin, Bo-Hyun,Woo, Jungmin,Won, Seunghee 대한생물정신의학회 2018 생물정신의학 Vol.25 No.1

Objectives This study intended to identify the deficits of cognitive control among patients with bipolar I disorder and their first-degree relatives, and identify the possibility of cognitive control as an endophenotype of bipolar disorder. Methods The study included three groups: euthymic states patients with bipolar I disorder (n = 55), unaffected first-degree relatives of probands with bipolar I disorder (n = 30), and a healthy control group (n = 51), that was matched on age, sex, and years of education. The AX version of the continuous performance test (CPT) was used to examine cognitive control. Error rate, correct response times of each subsets (AX, BX, AY, BY), and d' as an indication of accuracy sensitivity index were calculated. Psychopathology, intelligence, and psychomotor speed were also assessed. Results Patients with bipolar I disorder showed significantly worse error rates in the AX (p = 0.01) and BX (p = 0.02) subsets and d' (p = 0.05) than the others. They also showed more delayed correct response times than the healthy control group and first-degree relatives in all subsets (p < 0.01). But first-degree relatives showed neither high error rates nor delayed correct response times than healthy control group. Conclusions These findings suggest that cognitive control is impaired in bipolar I disorder but less likely to be an endophynotype of bipolar I disorder.

항정신병약물로 유발된 고프로락틴혈증을 가진 조현병 환자의 삶의 질

우선진(Seonjin Woo),진보현(Bo-Hyun Jin),원승희(Seunghee Won) 대한생물치료정신의학회 2018 생물치료정신의학 Vol.24 No.3

Objectives:Antipsychotic-induced hyperprolactinemia causes physical symptoms, such as amenorrhea, galactorrhea, gynecomastia, sexual dysfunction, and bone density loss, as well as psychiatric symptoms, such as depression and cognitive impairments. This study aimed to clarify the associations among hyperprolactinemia caused by antipsychotics in patients with schizophrenia, psychiatric pathology, and psychosocial factors. Methods:Ninety-nine patients with schizophrenia in the psychiatry department of a university hospital were registered between 2015 and 2017. All participants were assessed using structured questionnaires to elucidate psychopathology, social function, quality of life, and hyperprolactinemia-related side effects. The standard levels for hyperprolactinemia were 24ng/mL for women and 20ng/mL for men. Results:The average prolactin levels were 73.45±49.37ng/mL in patients with hyperprolactinemia and 9.16±6.42ng/mL in those without hyperprolactinemia. The average prolactin level in women was significantly higher than that in men(p=0.04). Risperidone was most commonly administered in patients with hyperprolactinemia(58.1%, p<0.01), while aripiprazole was most commonly administered in those without hyperprolactinemia(44.7%, p<0.01). Patients with hyperprolactinemia had significantly higher Positive and Negative Syndrome Scale(p=0.03) and Patient Health Questionnaire-9(p=0.05) scores and had significantly lower Social and Occupational Functioning Assessment Scale(p=0.04) and Strauss–Carpenter Levels of Functioning Scale(p=0.03) scores than patients without hyperprolactinemia. There were no significant differences in side effects or quality of life between the two groups. Conclusion:These findings demonstrate that hyperprolactinemia confers negative effects on depression and social function, but does not directly affect the quality of life. These results suggest that patients with schizophrenia who take antipsychotics that increase prolactin or cause side effects of hyperprolactinemia need to be assessed and receive interventions for depression.

보안성 향상을 위한 IoT 서비스 시스템 구현 및 평가

김진보(Jin-bo Kim),김미선(Mi-sun Kim),서재현(Jae-hyun Seo) 한국정보보호학회 2017 정보보호학회논문지 Vol.27 No.2

사물인터넷은 다양한 사물들로부터 발생되는 정보를 수집·공유·분석하여 사람들에게 유용한 정보 서비스를 제공하는 것을 의미한다. 본 논문은 사물인터넷 환경에서 발생하는 서비스 접근제어, 서비스 보안 기술 그리고 ID 관리 기술에 대한 서비스 영역에서의 보안 안전성을 향상시키는 방안을 제시한다. 서비스 보안의 안전성 향상을 위해 공개키 기반의 C&C(Certificate and Capability) 서비스 토큰 인증서를 설계하고 발급할 수 있는 서비스를 구현하였다. 또한 노드 디바이스로부터 수집된 데이터를 기반으로 리소스 서비스의 생성 시 이를 효율적으로 관리하고자 LCRS(Left Child-Right Sibling) 리소스 모델관리 방안과 서비스에 대한 접근제어를 위해 리소스 서비스 URI 보안 관리하는 IoT 서비스 시스템을 구현하였다. Internet of Things includes the whole process of collected information generated from a variety of objects, as well as analyzing and sharing it, and providing useful information services to people. This study seeks ways to improve security and safety in the areas of service security technology, ID management technology and service access control, all of which take place in the IoT environment. We have implemented the services that can design and issue C&C (Certificate and Capability) service token authentication, which is based on a public key, to improve the service security. In addition, we suggest LCRS (Left Child-Right Sibling) resource model management for the efficient control of resources when generating the resource services from the data collected from node devices. We also implemented an IoT services platform to manage URL security of the resource services and perform access control for services.

사물인터넷 서비스 접근제어를 위한 리소스 서비스 관리 모델 구현

김진보(Jin-Bo Kim),김미선(Mi-Sun Kim),서재현(Jae-Hyun Seo) 한국스마트미디어학회 2016 스마트미디어저널 Vol.5 No.3

사물인터넷 기술을 이용한 서비스 형태는 셀 수 없이 많으며, 현재도 여러 기관에서 다양한 서비스를 제공하기 위해 새로운 기술이나 프로토콜을 만들어 내고 있다. 본 논문은 사물인터넷 서비스 접근제어를 위한 시스템에서 효율적인 서비스 제공을 위한 리소스 서비스 모델을 설계하고 구현한다. 사용자가 접근하고자 하는 리소스 서비스를 LCRS(Left Child-Right Sibling) 트리를 이용하여 모델링하고, 리소스 서비스 토큰을 이용하여 서비스에 대한 접근 제어를 수행할 수 있다. Many countless services form using the Internet technology of things, in order to provide a variety of services in the current also many institutions, have created a new technology and protocols. In this paper, we design the resource service model for the efficient service provided by the system for controlling access to the Internet services of the things, to implement. The resources of the service that the user tries to access modeled using LCRS (Left Child-Right Sibling) tree, by utilizing the service token resource, it is possible to perform access control to services.

CapSG를 이용한 IoT 서비스 접근제어 플랫폼

김진보 ( Jin Bo Kim ),장데레사 ( Deresa Jang ),김미선 ( Mi Sun Kim ),서재현 ( Jae Hyun Seo ) 한국정보처리학회 2015 정보처리학회논문지. 소프트웨어 및 데이터 공학 Vol.4 No.9

사물인터넷(Internet of Things, IoT) 환경의 다양한 프로토콜, 도메인, 애플리케이션 위에서 유연한 서비스 제공을 위한 효율적인 사용자 권한 관리 방법이 필요하다. 본 논문은 IoT 환경의 다양한 서비스에 대한 효율적인 접근제어를 제공하기 위하여 CapSG(Capability Service Gateway)를 이용한 IoT 서비스 플랫폼을 제안하였다. CapSG는 인증과 접근 권한을 포함하는 토큰을 사용하여, 서비스 주체에 대한 인증 및 접근제어를 수행하여 서비스를 제공한다. 또한, 서비스 토큰 관리를 위한 생성, 위임, 폐기, 거절 등의 기능을 제공한다. 본 논문은 각 도메인에 대한 토큰 그룹을 사용함으로써 도메인별 서비스 접근제어가 가능하며, 토큰 그룹 내의 특정 서비스 토큰을 이용한 접근제어 수행도 가능하도록 설계하여 IoT의 다양한 서비스 요구에 대한 접근제어의 유연성과 효율성을 제공한다. There is great need for efficient user rights management method to provide a flexible service on variety protocols, domains, applications of IoT environments. In this paper, we propose a IoT service platform with CapSG to provide efficient access control for IoT various services of the environment. CapSG uses a token including authentication and access rights to perform authentication and access control service entity providing services. In addition, the generated token for service management, delegation, revocation, and provides a function such as denied. Also, it provides functions such as generation, delegation, disposal and rejection for service token management. In this paper, it provides the flexibility and efficiency of the access control for various services require of the IoT because of it is available to access control specific domain service by using the token group for each domain and is designed to access control using specific service token of tokens group.

웹 2.0과 Ajax 보안 취약점

김미선(Mi-Sun Kim),김진보(Jin-Bo Kim),양형초(Hyoung-Cho Yang),김용민(Yong-Min Kim),서재현(Jae-Hyun Seo) 한국정보과학회 2007 정보과학회지 Vol.25 No.10