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지용헌,김종우,차선희,신명철,신용원,정재삼 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.5
저자들은 1997 년 4 월 29 일 본원 산부인과에서 제왕절개분만 후 비장동맥류 자연파열 1 예를 경험하였기에 간단한 문헌 고찰과 함께 보고하는 바이다. Ruptured splenic artery aneurysm during pregnancy or delivery is very rare and it carries an exceedingly high mortality. The majority of splenic artery aneurysm ruptures during pregnancy occur in the third trimester. The literature reports a 25% mortality rate for ruptured splenic artery aneurysm. The mortality rate among pregnant women is high at 75% with a fetal mortality rate of 95%. The features of ruptured splenic artery aneurysm often include left flank or abdominal pain with radiation to the left shoulder, subsequently followed by severe left upper quadrant pain and shock. A double-rupture phenomenon may provide temporary tamponade with resolution of symptoms. A diagnosis of ruptured splenic artery aneurysm should be considered in any pregnant patient who complains of the sudden onset of severe left upper abdominal pain regardless of whether pain or shock is prominent at the time of evaluation. Maternal and fetal survival depends upon physician`s awareness of the possibility of splenic artery aneurysm rupture during pregnancy or postpartum, prompt recognition of the signs and symptoms of the condition, and immediate surgery to arrest hemorrhage. We have experienced one case of ruptured splenic artery aneurysm after cesarean delivery and reported with review of the literature.
지용헌,김정수,조동제,정창조,신명철,이미화,이경술,원종건 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.8
Actinomycoces is a gram positive, anaerobic, branching and non-acid fast bacterium which is a normal habitant of the skin, oral cavity, tonsil and gastrointestinal tract and its human infection is rare. Pelvic actinomycoses is frequently caused by Actinomycoces israel-ii. It is chronic, progressive, and more suppurative than granulomatous disease, and the symptoms are usually persistent and gradual, therefore the misdiagnosis and improper trea-tment are not uncommon. Actinomycoses is generally classified as cervicofacial, abdominal and thoracic type ac- cording to the site of the primary infection. Many actinomycotic pelvic infections in women used intrauterine device with long du- ration were reported, in contrast, others suggest that actinomycoces developed opportunistic infection irrespective of intrauterine device presence. We have experienced 4 cases of pelvic actinomycoses, one case with IUD(Lippes` loop) in a 47 year old woman, the other case with abdominal wall ctinomycoses in a 34 year old woman, the third case without IUD in a 41 year old woman, the fourth case with IUD(Cu-7) in a 37 year old woman and reported them with a review of literature.
지용헌,이숙환,차광열,김남근 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.5
저자들은 1995년 12월부터 1997년 2월까지 포천중문의과대학교 분당차병원에서 시행한 자궁내막암 환자 1예, 자궁경부암 환자 2예, 난소암 환자 1예, 양성 난소종양 2예, 경계성 난소종양 환자 2예, 전이성 난소암 1예 등 총 9예를 대상으로 SDS-폴리아크릴아마이드 젤 전기영동 방법으로 단백질 발현을 분석하여 다음과 같은 결과를 얻었다. 1. 자궁내막암 환자(lane 2, 3)에서는 12 kDa, 25 kDa, 31.5 kDa, 51.5 kDa, 62 kDa, 72 kDa의 단백질 에서 up-regulation 현상과 34.5 kDa의 새로운 단백질 의 발현이 관찰되었다. 2. 자궁경부암 환자(lane 4, 5)에서는 12 kDa, 25 kDa, 31.5 kDa, 51.5 kDa, 62 kDa, 72 kDa 단백질의 과발현 혹은 up-regulation 현상과 40 kDa 단백질의 down-regulation 현상이 각각 관찰되었다. 또한, lane 7 환자에서는 43.5 kDa, 62 kDa 단백질에서 과발현 현상이 관찰되었다. 3. 양성 난소종양 1예(lane 8, 9)에서는 18.8 kDa 과 40 kDa 단백질이 down-regulation 되었으며, 또 다 른 1예(lane 12)에서는 14 kDa과 67 kDa을 제외한 거 의 모든 단백질의 발현이 down-regulation되고 있음이 관찰되었다. 4. 난소암 환자 1예(lane 10, 11)에서는 18.8 kDa, 24 kDa과 38 kDa 단백질의 up-regulation 현상이 관찰 되었다. 5. 경계성 난소종양 2예(lane 13, 14)에서는 31.5 kDa 단백질의 down-regulation 현상이 관찰되었으며, 이들은 각각 24 kDa(lane 13)과 42 kDa(lane 14) 단백 질의 up-regulation 현상이 관찰되었다. 6. 전이성 난소암 1예(lane 15)에서는 다른 난소종 양 5예에서와 매우 유사한 단백질 발현을 보였으나, 42 kDa과 72 kDa 단백질의 발현에서 차이를 보였다. 위와 같은 결과로 미루어 자궁경부암 환자에서와 같이 공통적으로 단백질 발현에 증가나 감소가 일정 하게 나타나는 경우가 있는가 하면, 난소종양의 경우 환자간에 공통적으로 나타나는 단백질 발현변화 현상이 관찰되지 않았다. 이는 암을 일으키는 유전 자의 다양성으로 인해 같은 종류의 암세포에서도 서로 다른 단백질 발현 양상을 나타내게 하는 요인인 것으로 생각된다. We compared with the differences of protein expression between normal and tumor tissues in 1 case of endometrial cancer, 2 cases of cervical cancer, 2 cases of benign ovarian tumor and 4 cases of ovarian malignancies including two borderline tumors and one metastatic tumor by SDS-polyacrylamide gel electrophoresis (SDS-PAGE). The results were as follows: 1. In one endometrial cancer, 12 kDa, 25 kDa, 31.5 kDa, 51.5 kDa, 62 kDa and 72 kDa proteins were overexpressed or up-regulated (lane 2, 3), and a 34.5 kDa protein was newly expressed (lane 3). 2. In 2 cervical cancers, 12 kDa, 25 kDa, 31.5 kDa, 51.5 kDa, 62 kDa and 72 kDa proteins were overexpressed or up-regulated, and a 40 kDa protein was down-regulated (lane 4, 5 and 6, 7). 43.5 kDa and 62 kDa proteins were overexpressed in one patient (lane 6, 7). 3. In 2 benign ovarian tumors, 18.8 kDa and 40 kDa proteins were down-regulated (lane 8, 9), and almost all bands were down-regulated except 14 kDa and 67 kDa proteins (lane 12). 4. In one ovarian cancer, 18.8 kDa, 24 kDa and 38 kDa (lane 10, 11) proteins were up-regulated. 5. In 2 borderline ovarian tumors, a 31.5 kDa (lane 13, lane 14) protein was down-regulated. 24 kDa (lane 13) and 42 kDa (lane 14) proteins were up-regulated, respectively. 6. In one metastatic ovarian cancer (lane 15), 42 kDa and 72 kDa proteins were up-regulated. The differential display in our experiment showed at least one new (34.5 kDa), 11 up-regulated (12, 24,25, 31.5, 38, 42, 43.5, 51.5, 62, 67, 72 kDa) and 2 down-regulated (18.8, 40 kDa) bands. The protein patterns were similar between endometrial and cervical cancer, except for a 34.5 kDa in endometrial and a 43.5 kDa in cervical cancer.
지용헌(YH Chee),차인종(IJ Cha),김장흡(JH Kim),김도강(DK Kim) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.4
Twelve case of acute and subacute puerperal inversion were experienced at St. marys Hospital from 1974 to 1982, are studied to identify important predisposing factors and to assess management.