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Maternal influenza infection is associated with adverse pregnancy outcomes
조금준,김호연,안기훈,홍순철,오민정,김해중 한국모자보건학회 2018 한국모자보건학회 학술대회 연제집 Vol.2018 No.2
Background and Aim: This study aimed to determine whether maternal influenza infection is associated with adverse pregnancy outcomes. Methods: In this retrospective nationwide population-based study, we identified all women who delivered singleton between January 1, 2007 and December 31, 2010. Maternal influenza infection was identified using International Classification of Diseases-10th Revision (ICD-10) codes. Logistic regressions were used to estimate the Odds ratios and 95% confidence intervals (CIs) for the association between maternal influenza infection and adverse pregnancy outcomes. Result: Among 1,563,626 women who delivered singleton during the study period, 37,654 (2.4%) women were diagnosed with influenza infection during pregnancy. Infants born to mother with influenza during pregnancy had a lower birthweight compared with infants born to uninfected women. According to the logistic regressions models, maternal influenza infection associated with increased risk of preterm birth (OR 1.42, 95% CI 1.34-1.50), and low birth weight (OR 1.20, 95% CI 1.15-1.26). Conclusion: Maternal influenza infection was associated with adverse pregnancy outcomes. Therefore, further efforts are necessary to increase the uptake of influenza vaccination among pregnant women.
Is preeclampsia itself a risk factor for the development of metabolic syndrome after delivery?
조금준,정언석,심재영,이유진,배나영,최혜진,박종헌,김해중,오민정 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.4
ObjectiveThis study aimed to determine the association between preeclampsia and the postpartum development of metabolicsyndrome based on the pre-pregnancy status. MethodsKorean women who delivered their first child between January 1, 2011, and December 31, 2012, were enrolled. Allsubjects underwent a national health screening examination conducted by the National Health Insurance Corporation1 or 2 years prior to their first delivery and within 2 years after their first delivery. ResultsAmong the 49,065 participants, preeclampsia developed in 3,391 participants (6.9%). The prevalence of metabolicsyndrome was higher postpartum in women with preeclampsia than in those without preeclampsia (4.9% vs. 2.7%, respectively, P<0.001). Through the pre-pregnancy to postpartum period, women with preeclampsia had agreater increase in gestational weight retention, body mass index, waist circumference, systolic blood pressure,and triglyceride levels and a greater decrease in high-density lipoprotein cholesterol levels than women withoutpreeclampsia. Preeclampsia was associated with an increased risk of the postpartum development of metabolicsyndrome in women without pre-pregnancy metabolic syndrome (odds ratio, 1.28; 95% confidence interval, 1.05–1.56). However, preeclampsia was not associated with postpartum metabolic syndrome in women with pre-pregnancymetabolic syndrome or 2 components of metabolic syndrome. ConclusionIn this study, preeclampsia was associated with the postpartum development of metabolic syndrome in womenwithout pre-pregnancy metabolic syndrome. However, the effects were attenuated by predisposing risk factors in thepre-pregnancy period.
조금준,안정훈,최석주,오수영,권한성,홍순철,권자영 대한의학회 2015 Journal of Korean medical science Vol.30 No.12
The purpose of this study was to investigate postpartum glucose testing rates in patients with gestational diabetes mellitus (GDM) and to determine factors affecting testing noncompliance in the Korean population. This was a retrospective study of 1,686 patients with GDM from 4 tertiary centers in Korea and data were obtained from medical records. Postpartum glucose testing was conducted using a 2-hr 75-g oral glucose tolerance, fasting glucose, or hemoglobin A1C test. Test results were categorized as normal, prediabetic, and diabetic. The postpartum glucose testing rate was 44.9% (757/1,686 patients); and of 757 patients, 44.1% and 18.4% had pre-diabetes and diabetes, respectively. According to the multivariate analysis, patients with a high parity, larger weight gain during pregnancy, and referral from private clinics due to reasons other than GDM treatment were less likely to receive postpartum glucose testing. However, patients who had pharmacotherapy for GDM were more likely to be screened. In this study, 55.1% of patients with GDM failed to complete postpartum glucose testing. Considering the high prevalence of diabetes (18.4%) at postpartum, clinicians should emphasize the importance of postpartum diabetes screening to patients with factors affecting testing noncompliance.