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정상윤,황계연,김용진,김진,Jung, Sang-Yoon,Hwang, Gye-Yeon,Kim, Yong-Jin,Kim, Jin 한국산업경영시스템학회 1994 한국산업경영시스템학회지 Vol.17 No.31
The purpose of this study is to search for the most effective forecasting model for condenser with independent demand among the quantitative methods such as Brown's exponential smoothing method, Box-Jenkins method, and multiple regression analysis method. The criterion for the comparison of the above models is mean squared error(MSE). The fitting results of these three methods are as follows. 1) Brown's exponential smoothing method is the simplest one, which means the method is easy to understand compared to others. But the precision is inferior to other ones. 2) Box-Jenkins method requires much historic data and takes time to get to the final model, although the precision is superior to that of Brown's exponential smoothing method. 3) Regression method explains the correlation between parts with similiar demand pattern, and the precision is the best out of three methods. Therefore, it is suggested that the multiple regression method is fairly good in precision for forecasting our item and that the method is easily applicable to practice.
Fentanyl과 Midazolam이 생쥐 체외수정과 배아발달에 미치는 영향
정상윤(Sang Yoon Jung),이은주(Eun Joo Lee),양회생(Hoe Saeng Yang),심재철(Jae Chul Sim) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.6
N/A Ojective: To assess the effect of fentanyl and midazolam on in vitro fertilization rate and early embryo development in a mouse IVF model.Methods: Mouse oocytes were exposed in vitro to fentanyl at a concentration of 0(control), 50, 250, 500, 1000, 5000 pg/ml, and midazolam, 0(control), 2.5, 12.5, 25, 50, 250 ng/ml for 30 minutes, washed and inseminated. Thereafter fertilization was assessed. And subsequent in vitro development to the blastocyst stage was monitored daily.Results: Where fertilization occurred, subsequent embryo cleavage and development up to the blastocyst stage was affected significantly by the presence of fentanyl and midazolam solution in the medium(i.e., 14% to 31%, 10% to 35%), in comparison with control group( 60%, 62%).Conclusion: It can be concluded from these experiments that even a brief exposure of cumulus enclosed oocytes to a low concentration of fentanyl, midazolam is deleterious to subsequent cleavage.
서울시 장기 미집행 도시공원에 대한 행정적 재판단 연구
정상윤(Chong Brian Sang Yoon),김기영(Kim, Ki Young),권대중(Kwon, Dae Jung) 대한부동산학회 2014 大韓不動産學會誌 Vol.32 No.2
도시공원의 결정이 있은 이후 구체적인 공원조성 계획의 부재 또는 사업 인⋅허가 등 추진절차의 미이행 상태에서 10년 이상 장기 미집행 되고 있는 도시공원계획의 경우 장기미집행 상태에 있는 동안에 변화된 도시기능 및 상황을 적절히 반영하기 위해서라도 계획의 재판단이 필요하다. 이와 관련하여 이 연구는 장기 미집행 도시공원의 사업 단계에 따라 첫째, 인⋅허가 단계에서 사업중단된 장기 미집행 도시공원은 설치 계획에 대한 재원과 관련된 재판단이 있어야 함을 제시하였다. 둘째, 사업착수 단계에서는 과도한 재산권 침해 요인을 제거하기 위해 우선적인 토지보상과 개발행위 특례제도에 우선적 검토에 대한 재판단을 제시하였으며, 마지막으로 시설설치 단계에서는 재원마련에 대한 일시적 현상으로 사업이 수년간 지연됨에 대한 행정적 재정 배려와 자발적 공원시설 설치물에 대한 법적 미비요인에 대한 재판단이 필요함을 제시하였다. If you are planning a urban park for more than 10 years in long-term executory uninstalled condition, including members of the implementation procedures of the parks or business plan specific permission⋅ funny after the decision of the urban park and urban functions properly changed circumstances during the erm uninstalled condition the determination of the re-planning is needed even in order to reflect. In this regard, first, the level of long-term business interruption permission from⋅uninstalled Urban park was suggested that this should be re-determined and related resources in accordance with the business plan for the installation phase of the long-term research is uninstalled urban park. Second, the project outset was determined to re-present the first review on the primary land development activities and special compensation system to eliminate excessive infringement factors, and finally as a temporary phenomenon for funding this project for years facilities installed in step suggested the need for a re-determination of the legal factors, lack of park facilities for voluntary acts installations for fiscal consideration and deferred.
간 농양으로 오인 된 담도 확장 유발 담관내 유두 종양 1예
정상윤 ( Sang Yoon Chung ),김효정 ( Hyo Jung Kim ),김재선 ( Jae Seon Kim ),김백희 ( Baek Hui Kim ),이연호 ( Yun Ho Lee ),유양재 ( Yang Jae Yoo ),정용 ( Yong Jeong ),박영태 ( Young Tae Bak ) 대한췌담도학회 2013 대한췌담도학회지 Vol.18 No.4
담관내 유두 종양은 미세한 섬유혈관 중심을 감싸는 수많은 엽상의 유두상 주름이 발생하는 것을 특징으로, 종양자체나 혹은 종양의 잔해로 인한 폐쇄 혹은 과도하게 분비되는 점액으로 인해 담관이 막혀, 간내 담관이 확장되는 다발성의 종양으로, 췌관내 점액 유두 종양과 개념적으로 대척되어 이들 사이의 연관성을 연구 중이다. 최근 발열을 주소로 내원한 환자에서 복부초음파에서 간농양이 의심되어, 간농양의 원인을 찾고자 시행한 추가적 영상 검사에서 담관내 유두 종양이 의심되어 수술을 시행한 결과, 고도의 이형성을 동반한 점액 분비하는 간내 담관내 유두 종양으로 진단되었던 1예를 경험하였기에 문헌고찰과 함께 보고한다. Intraductal papillary neoplasm (IPN) of bile duct presents the tumor of a papillary surface comprising innumerable frondlike infolding of proliferation of columnar epithelial cells surroudings slender fibrovascular stalks. Neoplasm in the bile ducts which are dilated due to obstruction by a tumor itself, sloughed tumor debris, and excessive mucin. There are some researches of IPN of bile duct because they have same embryonic origin between IPN of bile duct and intraductal papillary mucinous neoplasm (IPMN) of pancreas. Patient with fever was suspected liver abscess in abdominal ultrasonography. Intraductal papillary neoplasm (IPN) of bile duct was suspected in additional imaging study. We experienced intraductal papillary neoplasm with high grade intraepithelial neoplasia after surgical resection. Here we report a case with the review of the reported literature.
한국인 성인 Henoch-Schonlein Purpura 환자의 임상적 특징
강윤 ( Yoon Kang ),하유정 ( You Jung Ha ),이광훈 ( Kwang Hoon Lee ),정상윤 ( Sang Youn Jung ),이상원 ( Sang Won Lee ),이수곤 ( Soo Kon Lee ),박용범 ( Young Beom Park ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.2
Objective: We investigated the clinical data and analyzed the significant prognostic factors for outcomes in Korean adult patients with Henoch-Schonlein Purpura (HSP). Methods: We retrospectively reviewed the medical records of 52 patients over 20 years-old, who visited the Yonsei University Severance Hospital from December 1999 to November 2009, and fulfilled the classification criteria for HSP. We investigated the epidemiologic data, clinical features, renal biopsy findings, laboratory results and disease outcomes. Results: The median age was 43.5 (20∼83) years old and 29 out of 52 patients (55.8%) were male. HSP exhibited seasonal variation and most frequently developed in winter (42.3%), followed by spring (25.0%). Upper respiratory infection was the most common known preceding event for HSP development. Skin manifestations were observed in all subjects, followed by kidney (80.8%), gastro-intestine (57.7%) and joints (26.9%). After a median follow-up period 14.5 (1∼227) months, 12 patients experienced HSP relapse (23.1%), and 7 patients had chronic renal failure (13.4%). Univariate analysis showed that renal insufficiency (p=0.002) and nephritic syndrome (p=0.026) at diagnosis were significantly related to the development of chronic renal failure. Of the two parameters, only initial renal insufficiency was found to be a significant predictive value for chronic renal failure (OR=28.7, p=0.001, 95% confidential interval 3.6∼225.3). Conclusion: Renal insufficiency at diagnosis may be a useful predictive factor for progression to chronic renal failure in Korean adult patients with HSP.
크론병 환자에서 인플릭시맵과 메살라진 치료 후 발생한 지연발생 급성 세뇨관간질 신염 증례
유양재 ( Yang Jae Yoo ),정상윤 ( Sang Yoon Chung ),구대회 ( Dae Hoe Gu ),고강지 ( Gang Jee Ko ),표희정 ( Heui Jung Pyo ),권영주 ( Young Joo Kwon ),박영태 ( Young Tae Bak ),원남희 ( Nam Hee Won ) 대한소화기학회 2014 대한소화기학회지 Vol.63 No.5
Infliximab is a chimeric anti-tumor necrosis factor-alpha monoclonal antibody. Infusion related reactions and infection are well known side effects of infliximab; however, renal complications have not been well recognized. We report on a patient with late onset-acute tubulointerstitial nephritis (ATIN) after treatment with infliximab and mesalazine for Crohn’s disease. A 25-year-old woman was admitted with a purpuric rash on both lower extremities and arthralgia. She had been diagnosed with Crohn’s disease 5.6 years previously and had been treated with mesalazine and infliximab. Serum creatinine level, last measured one year ago, was elevated from 0.6 mg/dL to 1.9 mg/dL. Results of urinalysis, ultrasound, and serologic examinations were normal. With a tentative diagnosis of Henoch-Schonlein purpura, oral prednisolone was given, and serum creatinine decreased to 1.46 mg/dL, but was elevated to 2.6 mg/dL again at two months after discontinuation of prednisolone. Renal biopsy indicated that ATIN was probably ind ced by drug, considering significant infiltration of eosinophils. Concomitant use of infliximab with mesalazine was supposed to trigger ATIN. Oral prednisolone was administered, and serum creatinine level showed partial recovery. Thus, ATIN should be suspected as a cause of renal impairment in Crohn’s disease even after a long period of maintenance treatment with infliximab and mesalazine.
김광수(Kwang Soo Kim),정상윤(Sang Yoon Jung) 한국품질경영학회 2001 품질혁신 Vol.2 No.1
In the case of Value Engineering, the start ranking decision rule by using the MCDM (Multi-Criteria Decision Making) are is complicated to apply to the multifunction fields. The purpose of this study is to solve the problem point of the start ranking decision rule as applying the TOPSIS(Technique for Order Preference by Similarity to Ideal Solution) model for MCDM, which is able to do compensatory preference. A numerical example is presented to illustrate the application of the TOPSIS model.
증례 : 류마티스 ; 분류 불능형 면역 결핍증(Common Variable Immunodeficiency)과 병발된 쇼그렌 증후군 1예
강산하 ( San Ha Kang ),조혜정 ( Hye Jeong Cho ),홍희진 ( Hee Jin Hong ),홍소담 ( So Dam Hong ),김보혜 ( Bo Hye Kim ),정상윤 ( Sang Yoon Jung ),최진정 ( Jin Jung Choi ) 대한내과학회 2015 대한내과학회지 Vol.89 No.2
Common variable immunodeficiency (CVID) is a heterogeneous group of primary immune deficiencies in adults characterized by hypogammaglobulinemia, recurrent bacterial infections, and a higher incidence of autoimmune diseases. More than 25% of CVID patients also have autoimmune diseases such as autoimmune hemolytic anemia, immune thrombocytopenic purpura, rheumatoid arthritis, and systemic lupus erythematosus. However, the pathogenesis of autoimmunity in CVID remains obscure. We report a 56-year-old woman with CVID and Sjogren`s syndrome. In addition to a long history of recurrent upper respiratory infections, acute gastroenteritis, and cellulitis, she has also suffered from persistent xerostomia and xerophthalmia for the past 10 years. Serologic studies revealed hypogammaglobulinemia (low levels of IgG, IgA, and IgM in serum) and the presence of anti-Ro antibodies, and salivary scintigraphy indicated salivary gland involvement. These findings led to a diagnosis of CVID and Sjogren`s syndrome, which was treated by monthly intravenous immunoglobulin therapy. (Korean J Med 2015,89:254-258)