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하유정 ( You Jung Ha ),이광훈 ( Kwang Hoon Lee ),정샹윤 ( Sang Youn Jung ),박현성 ( Hyun Sung Park ),이수곤 ( Soo Kon Lee ),박용범 ( Young Beom Park ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.3
Wegener`s granulomatosis is a multisystem necrotizing vasculitis that primarily involves the upper and lower respiratory tract and kidneys but can affect almost any organ, including the central nervous system. Cerebral infarction and intracerebral hemorrhage are rare neurologic complications of Wegener`s granulomatosis. We report on a 52-year-old male patient with Wegener`s granulomatosis presenting with a cerebral infarction and subsequent intracerebral hemorrhage. He was successfully treated with high dose corticosteroid and cyclophosphamide.
하유정 ( You Jung Ha ),정상윤 ( Sang Youn Jung ),이광훈 ( Kwang Hoon Lee ),최준정 ( Jun Jung Choi ),이광길 ( Kwang Kil Lee ),이수곤 ( Soo Kon Lee ),박용범 ( Yong Beom Park ) 대한류마티스학회 2009 대한류마티스학회지 Vol.16 No.4
Dermatomyositis is a rare inflammatory myopathy with characteristic skin manifestations and accompanied by muscular weakness. Vesicle formation in dermatomyositis is rare. We report a case of dermatomyositis associated with ovarian cancer in a 62-year-old woman who had vesicles and bullae on her arms. She had erythema and edema on the face, chest, abdomen, and shoulder for 2 months. Diagnosis of dermatomyositis was established by clinical manifestations, muscle enzyme elevation, and a characteristic electromyogram. She was successfully treated with cyclosporin and high doses of steroids.
8, 9번 삼염색체를 가진 골수형성이상증후군과 정신분열증을 동반한 베체트병
백정훈 ( Jung Hoon Baek ),전현정 ( Hyun Jung Chun ),박윤희 ( Youn Hee Park ),조정현 ( Jeong Hyeon Cho ),배상균 ( Sang Kyun Bae ),하유정 ( You Jung Ha ) 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.6
Behcet`s disease (BD) is a multi-systemic inflammatory disease of unknown origin that affects nearly all organs. Recent reports of BD with myelodysplastic syndrome (MDS) often note an association with gastrointestinal involvement and trisomy 8. We herein report on a case of a 51-year-old man who had refractory schizophrenia and developed gastrointestinal BD and MDS with trisomy 8 and 9. He visited our hospital due to fever and abdominal pain. Multiple ulcerations in the colorectum were observed on colonoscopy, and he was diagnosed with intestinal BD. During the treatment of intestinal BD, anemia and thrombocytopenia developed. His bone marrow study revealed myelodysplastic syndrome (refractory anemia with ringed sideroblast) with trisomy 8 and trisomy 9. We report a rare case of intestinal BD accompanied by schizophrenia and myelodysplastic syndrome with trisomy 8 and 9.
한국인 성인 Henoch-Schonlein Purpura 환자의 임상적 특징
강윤 ( Yoon Kang ),하유정 ( You Jung Ha ),이광훈 ( Kwang Hoon Lee ),정상윤 ( Sang Youn Jung ),이상원 ( Sang Won Lee ),이수곤 ( Soo Kon Lee ),박용범 ( Young Beom Park ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.2
Objective: We investigated the clinical data and analyzed the significant prognostic factors for outcomes in Korean adult patients with Henoch-Schonlein Purpura (HSP). Methods: We retrospectively reviewed the medical records of 52 patients over 20 years-old, who visited the Yonsei University Severance Hospital from December 1999 to November 2009, and fulfilled the classification criteria for HSP. We investigated the epidemiologic data, clinical features, renal biopsy findings, laboratory results and disease outcomes. Results: The median age was 43.5 (20∼83) years old and 29 out of 52 patients (55.8%) were male. HSP exhibited seasonal variation and most frequently developed in winter (42.3%), followed by spring (25.0%). Upper respiratory infection was the most common known preceding event for HSP development. Skin manifestations were observed in all subjects, followed by kidney (80.8%), gastro-intestine (57.7%) and joints (26.9%). After a median follow-up period 14.5 (1∼227) months, 12 patients experienced HSP relapse (23.1%), and 7 patients had chronic renal failure (13.4%). Univariate analysis showed that renal insufficiency (p=0.002) and nephritic syndrome (p=0.026) at diagnosis were significantly related to the development of chronic renal failure. Of the two parameters, only initial renal insufficiency was found to be a significant predictive value for chronic renal failure (OR=28.7, p=0.001, 95% confidential interval 3.6∼225.3). Conclusion: Renal insufficiency at diagnosis may be a useful predictive factor for progression to chronic renal failure in Korean adult patients with HSP.
유희태 ( Hee Tae Yu ),하유정 ( You Jung Ha ),정상윤 ( Sang Youn Jung ),이광훈 ( Kwang Hoon Lee ),김현민 ( Hyun Min Kim ),이수곤 ( Soo Kon Lee ),박용범 ( Yong Beom Park ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.2
Septic arthritis of the sternoclavicular joint is a rare condition. The predisposing risk factors include intravenous drug abuse, subclavian vein catheter placement, diabetes mellitus and trauma. Delayed or inadequate management can lead to irreversible joint damage with subsequent disability, even death. We report a 48-year-old female patient who presented with right sternoclavicular joint swelling and right shoulder pain. Magnetic resonance imaging of the sternum showed swelling of the right sternoclavicular joint with gadolinium enhancement. Synovial fluid and bone tissue culture revealed Escherichia coli (E.coli), and confirmed the diagnosis of sternoclavicular septic arthritis. She was successfully treated with surgical debridement and ciprofloxacin without recurrence. This is the first case report of E.coli sternoclavicular septic arthritis in Korea.
허재형 ( Jaehyung Hur ),하유정 ( You Jung Ha ),정상완 ( Sang Wan Chung ),강은하 ( Eun Ha Kang ),송영욱 ( Yeong Wook Song ),이윤종 ( Yun Jong Lee ) 대한내과학회 2018 대한내과학회지 Vol.93 No.4
저자들은 혈액 및 활막액 호산구증가증이 동반된 급성 무릎 단관절염 환자에서 개회충증 감염을 진단하고 글루코코르티코이드 관절강내 주사와 함께 알벤다졸 투약을 통하여 치료한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Eosinophilic synovial effusion is rarely observed in patients with inflammatory nature of synovial fluid, and the differential diagnosis includes parasitic arthritis. Toxocariasis is the one of the most common forms of helminthiasis worldwide and has been reported as a common cause of peripheral blood eosinophilia in Korea. However, joint involvement has been rarely reported in adults with toxocariasis in the English-language literature. Here, we report the first Korean case of a female presenting with acute monoarthritis with an increased number of eosinophils in the peripheral blood and synovial fluid, who was finally diagnosed with toxocariasis. (Korean J Med 2018;93:409-412)
우중하엽 폐허탈 및 폐쇄세기관지기질화 폐렴을 유발한 기관지 지방종
손지영 ( Ji Young Son ),정지예 ( Ji Ye Jung ),하유정 ( You Jung Ha ),홍수정 ( Soo Jung Hong ),정민규 ( Min Kyu Jung ),정문재 ( Moon Jae Chung ),서용성 ( Yong Sung Seo ),문지애 ( Ji Ae Moon ),변민광 ( Min Kwang Byun ),박병훈 ( Byun 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.4
Lipoma is a common neoplasm in soft tissues. However, an intrapulmonary lipoma is a rare benign tumor. Patients with a bronchial lipoma might have a malignant potential related to their smoking history due to the case reports of lung cancer accompanied with lipoma. Endobronchial lipoma can cause irreversible parenchymal lung damage if not diagnosed and treated early. Therefore, it should initially be treated by fiberoptic bronchoscopy or surgery depending on the status of distal parenchymal lung damage. Bronchiolitis obliterans with organizing pneumonia (BOOP) is a pathological syndrome that is defined by the presence of buds of granulation tissue consisting of fibroblasts and collagen within the lumen of the distal air spaces. BOOP is caused by drug intoxication, connective tissue disease, infection, obstructive pneumonia, tumors, or an unknown etiology. We encountered a 58 year-old male patient with endobronchial lipoma, causing the collapse of the right middle and lower lobes, and BOOP due to obstructive pneumonia. (Tuberc Respir Dis 2008;65:313-317)
베체트병 환자에서 발생한 Lenticulostriate 동맥류 파열 1예
황성준 ( Seongjun Hwang ),장성혜 ( Sung Hae Chang ),정상완 ( Sang Wan Chung ),하유정 ( You Jung Ha ),강은하 ( Eun Ha Kang ),송영욱 ( Yeong Wook Song ),이윤종 ( Yun Jong Lee ) 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.5
베체트병의 환자에서 뇌동맥류는 흔치 않은 중추신경계침범 임상상이며, 특히 lenticulostriate 동맥류가 발생하는 경우는 매우 드물다. 저자들은 활동성 베체트병에의한 lenticulostriate 동맥류 파열로 발생한 급성 좌측 편마비환자에서 고용량 글루코코르티코이드제제 투여로 호전된 국내첫 번째 증례를 경험하였기에 문헌고찰과 함께 보고한다. Behcet`s disease (BD) is characterized by recurrent oro-genital ulcers, skin lesions, and intraocular inflammation, but can also affect various internal organs. Vascular BD usually presents with luminal stenosis, thrombosis, or aneurysm formation in aorta and peripheral arteries. However, intracranial artery involvement has been uncommonly reported in patients with BD and BD cases with lenticulostriate artery aneurysm have been rarely described in the English-language literature. We hereby reported the first case of a Korean BD patient presenting with a ruptured lenticulostriate artery aneurysm, who received medical treatment, and reviewed the literature on reported cases of BD with intracranial aneurysms. (J Rheum Dis 2015;22:317-321)