경막외 진통은 비경막외 진통에 비해 초산부의 분만을 지연시키는가?: 후향성 관찰 연구

장소영,이애령,윤소희,최윤숙,박종국,조우진,Jang, So Young,Lee, Ae Ryoung,Yun, So-hui,Choi, Yun Suk,Park, Jong Cook,Cho, Woo Jin 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.2

We conduct this study to compare the difference in duration of labor in nulliparous women received epidural analgesia or non-epidural analgesia for labor pain. This retrospective, observational study based on the review of the medical records from February 2014 to July 2017. Epidural analgesia was initiated with a 10 mL epidural bolus of 1% lidocaine and was maintained with a 0.1% mixture of ropivacaine with fentanyl. Non-epidural analgesia was initiated with pethidine 12.5 mg bolus, followed by additional boluses as needed. The primary outcome was the duration of the labor. 149 healthy nulliparous women at term pregnancies with no evidence of fetal distress were enrolled in this study. 92 women received non-epidural analgesia (Group NE) and 57 women received epidural analgesia (Group E). There were no significant differences between the two groups in maternal demographic characteristics. Using a Kaplan-Meier survival analysis, there was no significant difference in the overall duration of the labor(P=0.233). The duration of the first stage of labor was $187.6{\pm}167.3min$ in Group NE, $248.6{\pm}168.7min$ in Group E (Mean${\pm}$SD, P=0.032). The duration of the second stage of labor was $67.1{\pm}57.8min$ in Group NE, $64.1{\pm}47.5min$ in Group E (Mean${\pm}$SD, P=0.693). Epidural analgesia delayed the first stage of labor in this study. But there were no significant differences between the two groups in the duration of the second stage and the total duration of labor.

비색법을 이용한 모자간 우식 경험 및 활성의 상관성

장소영,이고은,송제선,김성오,이제호,최형준,Jang, So-young,Lee, Koeun,Song, Je Seon,Kim, Seong-Oh,Lee, Jaeho,Choi, Hyung-Jun 대한소아치과학회 2018 大韓小兒齒科學會誌 Vol.45 No.2

본 연구의 목적은 새로운 비색법인 $Cariview^{(R)}$를 이용한 우식 활성 검사의 타당성 및 모자간 우식 경험 및 활성의 상관성 평가를 하고 기존의 특정 세균 배양법인 $CRT^{(R)}$ bacteria 검사와 비교 평가하는 것이다. 만 6세 미만 어린이 - 어머니 34쌍(총 68명)이 사전 동의 하에 연구에 참여하였다. 설문 조사 및 구강 검사 후 우식 활성 검사인 $Cariview^{(R)}$와 $CRT^{(R)}$ bacteria 검사를 각각의 대상자에게 시행하였다. 실험 결과 $Cariview^{(R)}$ 점수는 어린이의 우식 경험 유치수(dft)와 통계적으로 유의한 상관성을 나타냈고(r = 0.598, p < 0.01) 상관 정도는 $CRT^{(R)}$ bacteria 점수보다 높았다. $Cariview^{(R)}$ 점수는 어머니와 어린이의 우식 치아수(DT, dt)와 통계적으로 유의한 상관성을 나타냈다(p < 0.05). $Cariview^{(R)}$와 $CRT^{(R)}$ bacteria 검사 모두에서 모자간 우식 경험 및 우식 활성은 통계적으로 유의한 상관성을 나타내지 않았다(p > 0.05). $Cariview^{(R)}$ 비색법은 어린이의 치아 우식 경험 및 현재의 치아 우식 상태를 적절히 반영하며 우식 위험도를 예측하고 예방 전략을 수립하는 데 임상적으로 유용할 것으로 판단된다. The purpose of this study was to compare the validity of $Cariview^{(R)}$, a new colorimetric caries activity test, with $CRT^{(R)}$ bacteria, a conventional bacterial culture method. In addition, this study assesses the correlation between the dental caries experience and activity between mothers and their children. 34 pairs of mothers and their children under the age of 6 years participated in this study with informed consent. After filling out a questionnaire and oral examination, the two caries activity tests above were performed on each subject. In the results, $Cariview^{(R)}$ scores were statistically significant with children's caries experience (r = 0.598, p < 0.01) and showed higher correlation than $CRT^{(R)}$ bacteria scores. $Cariview^{(R)}$ scores showed statistically significant correlation with the number of decayed teeth in both mothers and children (p < 0.05). In both $Cariview^{(R)}$ and $CRT^{(R)}$ bacteria tests, there was no statistically significant correlation between caries experience and caries activity (p > 0.05). $Cariview^{(R)}$ colorimetric test will be clinically useful for predicting future caries risk and establishing a preventative strategy in pediatric dentistry.

인체거대세포바이러스에 의한 인체 단핵구세포의 세포주기 저해

장소영,김미숙,이찬희,Jang, So-Young,Kim, Mi-Suk,Lee, Chan-Hee 한국미생물학회 2008 미생물학회지 Vol.44 No.4

마이엘로이드 계열의 단핵세포는 인체세포거대바이러스(human cytomegalovirus, HCMV)의 잠복 부위로 알려져 있다. 다양한 세포에서 HCMV에 의한 세포주기의 촉진 또는 억제에 관한 연구는 많이 있었지만, 단핵세포에서의 연구는 거의 없는 상태이다. 이에 본 연구에서는 단핵세포에 HCMV가 감염되면 세포주기에 어떤 변화가 나타나는지 알아보고자 하였다. Propidium iodide를 이용한 유세포 분석을 통한 세포주기 분석에서 HCMV에 감염된 THP-1 세포에서는 G0-G1기가 증가하고, 그만큼 S가 감소함을 보았다. 반면 HL-60 세포에서는G0-G1기와 S기의 상대적인 비율에 큰 변화가 없었다. BrdU 유입 실험에서 THP-1세포의 DNA 합성이 HCMV 감염에 의해 억제됨을 알 수 있었다. 세포주기의 G1기에서 S기로의 전환을 억제하는 p21 단백질은HCMV에 감염된 THP-1 세포에서는 발현이 유도되었지만 HL-60 세포에서는 거의 발현이 되지 않았다. 따라서 HCMV는 promocyte THP-1 세포에서 p21 단백질의 유도에 의해 세포주기를 G0-G1기에서 억류함에 따라 세포중식을 억제하는 것으로 생각된다. Monocytic cells in myeloid lineage are known for latent site of HCMV Previous studies have suggested that HCMV regulates cell cycle progression in a variety of cells, but studies in monocytic cells are limited. In this study, we attempted to understand cell cycle changes after HCMV infection in the monocytic cell lines. Flow cytometric analyses using propidium iodide revealed that the proportion of G0-G1 phase was increased and the proportion of S phase decreased in HCMV-infected THP-1 cells, but not in HL-60 cells. BrdU-incorporation assay supported that cell proliferation was inhibited in HCMV-infected THP-1 cells by inhibition of de novo DNA synthesis. Western blot analysis revealed that p21, inhibitor of cell cycle progression from G1 phase to S phase, was induced in HCMV-infected THP-1 cells but not in HL-60 cells. Thus, HCMV inhibited cell pro-liferation by arresting the cell cycle at G0-G1 phase through induction of p21 protein in promocytic THP-1 cells.

여성건강보험 입원 및 수술급부금 지급분석

장소영,김용은,Jang, So-Young,Kim, Yong-Eun 한국생명보험의학회 2002 保險醫學會誌 Vol.21 No.-

장기간병보험(長期看病保險)의 언더라이팅

장소영,Jang, So-Young 한국생명보험의학회 2004 保險醫學會誌 Vol.23 No.-

논문 : 기름의 종류 및 첨가량을 달리한 구운 약과의 품질특성 연구

장소영 ( So Young Jang ),박미정 ( Mi Jung Park ),이숙영 ( Sook Young Lee ) 한국식생활문화학회 2013 韓國食生活文化學會誌 Vol.28 No.5

This study aimed to find oils that can replace high-priced sesame oil.The quality of baked Yackwa containing different types of oils (rice bran, olive, or sesame oils) and amount of oils (30, 35, 40%) were investigated. The hardness of the baked Yackwa depended on the amount of oil, as more oil led to a softer texture of baked Yackwa. According to sensory evaluations, baked Yackwa with rice bran oil received the highest score in taste quality, with sesame oil receiving the second highest score. The flavor of baked Yackwa containing the rice bran oil was also better than other samples. In contrast, there were no significant differences in taste between other samples, including baked Yackwa containing all ingredients, 40%sesame oil, and 40% olive oil. The overall acceptance showed the highest score in baked Yackwa with rice bran oil (35%). In conclusion, rice bran oil (35%) is recommended as an oil ingredient for baked Yackwa.

초계탕의 시대적 변천에 대한 연구

장소영 ( So Young Jang ),한복려 ( Bok Ryo Han ) 한국식생활문화학회 2012 韓國食生活文化學會誌 Vol.27 No.5

영어 글쓰기 능력, 편향성, 채점시간이 예비 영어교사들의 채점 신뢰도에 미치는 영향

장소영 ( Jang So Young ),박묘영 ( Park Myo Young ) 글로벌영어교육학회 2021 Studies in English education Vol.26 No.4

This study aims to investigate the rating performance of Korean pre-service secondary school English teachers. Twenty-seven secondary student teachers participated in both self and peer rating sessions because they scored 27 essays after they had written a one-page essay with the given topic. They were asked to make comments on essays, and rating time for each essay they spent right after they finished scoring each assessment criterion. The results exhibited that, first, most of the participants did consistently assign their scores, but no statistically significant association was found between their writing ability and their consistency in scoring. Second, some biases on self and peer rating were found. Participants showed that they tended to score the essays at the higher levels of proficiency more severely. On the contrary to this, they were likely to assign more lenient scores to the essays at the lower levels of proficiency. Third, the length of the rating time they spent was not directly related to maintaining intra-rater reliability. The findings of this study have some educational implications for training pre-service teachers.

Rasch 측정 모형을 이용한 문법 학습전략 도구개발의 타당화 연구

장소영 ( Jang So Young ),이성영 ( Lee Sung Young ) 대한영어영문학회 2013 영어영문학연구 Vol.39 No.4

The purpose of this study aims to validate a survey instrument for grammar learning strategy in English so as to develop a standard survey instrument. The survey consisted of 52 items with a 5-point Likert scale and was designed based on Oxford’s Strategy Inventory for Language Learning(SILL). The items were revised partly in order to reflect grammar learning process. Research was conducted with a total of 335 college students, and the data were analyzed using Rasch measurement model. The results were summarized in terms of two perspectives; validity and reliability of survey instrument. First, in terms of content validity, the study found the overall content validity adequate, and survey could measure unidimensional construct. In addition, it was found that the 5 point-scale was appropriate to elicit responses. However, some recommendations were made for improvement. Redundancy among items was found based on the analyses of fit statistics and point-biserial correlation. Second, the results showed that reliability of a survey instrument including both items and respondents was high based on the index of reliability. (Kunsan National University)

래쉬 모형을 사용한 표준화 시험의 타당성 평가: 시·도 교육청 주관 중학생 영어듣기시험을 중심으로

장소영 ( Jang So Young ),김태영 ( Kim Taeyoung ) 글로벌영어교육학회(구 호남영어교육학회) 2016 Studies in English education Vol.21 No.2

The main purpose of this study is to analyze the effects of the nationwide standardized listening tests for the middle school students in Korea. In this study, the validity of the test is evaluated by adopting the Rasch measurement model. Responses of 60 students on 20 listening test items were collected and analyzed. The results reported empirical evidence step by step on the basis of the validation procedures Wolfe and Smith suggested. The findings are as follows. First, Cronbach alpha coefficient is of .81 showing that this test is reliable, although some misfit test items were found. Second, judging from the item-person map, the test does not have difficult items enough to properly evaluate high level students. Finally, suggestions for teaching and learning are discussed. The Rasch analysis provides a simple and useful map which can be used as a way of giving proper feedback to the students. It shows the test items distributed in six dimensions, indicating that the correct or incorrect items are either above, within, or below the ability level of a student as well as the overall evaluation of test validity. It is expected to make it possible for a language teacher to carry out the measurement-driven instruction Cheng suggested by linking test results and classroom practices.