코로나19 팬데믹이 간호대학생의 대학생활적응에 미치는 영향 : 공감능력, 지각된 스트레스, 회복탄력성을 중심으로

최윤숙,김미영 대한통합의학회 2024 대한통합의학회지 Vol.12 No.1

Purpose : In this study, we aimed to determine the impact of the COVID-19 pandemic on nursing students' adjustment to college life by focusing on their empathic ability, perceived stress, and resilience. Methods : We applied a descriptive survey research design, which included a self-report questionnaire. The participants comprised 307 nursing students in B city. The data were analyzed by calculating the percentages, means, standard deviations, t-tests, ANOVA, Scheffé test, Pearson's correlation coefficients, and hierarchical regression using SPSS 23.0. Results : The participants' empathic ability score was 3.30±.42, perceived stress score 1.85±.49, resilience score 3.44±.64, and adjustment to college life score 3.25±.52. Adjustment to college life was positively correlated with resilience (r=.43, p<.001) but negatively correlated with perceived stress (r=.27, p<.001). Factors affecting adjustment to college life include, among general characteristics in Model 1, in descending order, major satisfaction-satisfied (β=.54, p<.001), interpersonal conflict: never (β=.26, p=.018), health status: healthy (β=.25, p=.002), character: positive (β=.21, p=.006), character: optimistic (β=.19, p=.015), parents' economic power: high (β=.15, p=.047), and gender: male (β=.11, p=.016). Model 1 was statistically significant (F=11.67, p<.001), and the explanatory power was 41 %. In Model 2, empathic ability, perceived stress, and resilience were added as independent variables. When including the dependent variables, the factors that most influenced adjustment to college life were perceived stress (β=-.37, p<.001), major satisfaction-satisfied (β=.36, p<.001), health status-healthy (β=.25, p<.001), gender-male (β=.10, p=.015), and resilience (β=.10, p=.029). Model 2 was statistically significant (F=17.65, p<.001), and the explanatory power was 56 %. Conclusion : We found that gender, major satisfaction, health status, perceived stress, and resilience affected adjustment to college life among nursing students who had experienced the COVID-19 pandemic. To increase their ability to adjust to college life, a gender-specific intervention program should be developed that can improve the students' health status, major satisfaction and resilience, and reduce their perceived stress.

Ultrasound-guided femoral and popliteal sciatic nerve blocks for below knee surgery in patients with severe cardiac disease

최윤숙,신현주,박지용,김현정,윤소희 대한마취통증의학회 2015 Korean Journal of Anesthesiology Vol.68 No.5

db/db 마우스에서 IH-901의 항 당뇨 활성

최윤숙,한기철,한은정,박금주,박종석,성종환,정성현,Choi, Yun-Suk,Han, Gi-Cheol,Han, Eun-Jung,Park, Keum-Joo,Park, Jong-Suk,Sung, Jong-Hwan,Chung, Sung-Hyun 대한약학회 2006 약학회지 Vol.50 No.6

The pharmacological properties of ginseng are mainly attributed to ginsenosides, the active constituents that are found in the extracts of different species of ginseng. Lately; the studies on ginsenosides are mainly focused on IH-901, a major intestinal bacterial metabolite of ginsenosides. In this study; we examined the anti-diabetic activity of IH-901 in C57BU61 db/db mice model. IH-901 was administrated orally at a dose of 20 mg/kg for 5 weeks. During the experimental period, body weight and blood glucose levels were measured every week. After 5 weeks, db/db mice were sacrificed and diabetic parameters were analyzed. IH-901 treated group showed a significant decrease in fasting blood glucose levels (from 10.5 mM to 9.4 mM), insulin resistance index (from 163.6 to 100.2) and triglyceride levels (from 115.3 to 70.1) compared to the diabetic control. In Pancreatic islets morphology; IH-901 treated group revealed much less infltrated mononuclear cells, indicating that IH-901 recovered ${\beta}$-cell damage due to hyperglycemia. In addition, IH-901 upregulated expressions of glucose transporter 4 (GLUT4) and PPAR-${\gamma}$ in skeletal muscle and adipose tissue, respectively. Taken together IH-901might be a potential anti-hyperglycemic agent with insulin sensitizing effect.

Indigo carmine enhances phenylephrine-induced contractions in an isolated rat aorta

최윤숙,옥성호,이승민,박상승,하유미,장기철,김혜정,신일우,손주태 대한마취통증의학회 2011 Korean Journal of Anesthesiology Vol.61 No.1

Background: The intravenous administration of indigo carmine has been reported to produce transiently increased blood pressure in patients. The goal of this in vitro study was to examine the effect of indigo carmine on phenylephrine-induced contractions in an isolated rat aorta and to determine the associated cellular mechanism with particular focus on the endothelium-derived vasodilators. Methods: The concentration-response curves for phenylephrine were generated in the presence or absence of indigo carmine. Phenylephrine concentration-response curves were generated for the endothelium-intact rings pretreated independently with a nitric oxide synthase inhibitor, Nω-nitro-L-arginine methyl ester (L-NAME), a cyclooxygenase inhibitor, indomethacin, and a low-molecular-weight superoxide anion scavenger, tiron, in the presence or absence of indigo carmine. The fluorescence of oxidized dichlorofluorescein was measured in rat aortic vascular smooth muscle cells cultured in the control, indigo carmine alone and tiron plus indigo carmine. Results: Indigo carmine (10^-5 M) increased the phenylephrine-induced maximum contraction in the endotheliumintact rings with or without indomethacin, whereas indigo carmine produced a slight leftward shift in the phenylephrine concentration-response curves in the endothelium-denuded rings and L-NAME-pretreated endothelium-intact rings. In the endothelium-intact rings pretreated with tiron (10^-2 M), indigo carmine did not alter phenylephrine concentration-response curves significantly. Indigo carmine (10^-5 M) increased the fluorescence of oxidized dichlorofluorescein in the vascular smooth muscle cells, whereas tiron abolished the indigo carmineinduced increase in oxidized dichlorofluorescein fluorescence. Conclusions: Indigo carmine increases the phenylephrine-induced contraction mainly through an endotheliumdependent mechanism involving the inactivation of nitric oxide caused by the increased production of reactive oxygen species.

Aminoglycoside系 抗生物質과 Na-Alginate 製劑 倂用에 의한 相互作用

최윤숙,이상헌,김재백 圓光大學校 藥品硏究所 1986 藥品硏究所報 Vol.1 No.1

In clinic, a drug administers to patients by the ad-mixed injection or the coincidental administration of intravenous and intramuscular injection. Thin drug toxicity or effect may be changed by the interaction. We thought that the coincidental administration of aminoglysoside antibiotics and Na-alginate preparation effected for renal function and renal tissue. So nave experimented on the renal damage in rabbits. which the coincidental adminstration of antibiotics and Na-alginate was been done. by microscopic finding blood urea nitrogen levels and creatinine levels. The results were as follows, 1) In intramuscular injection, nephrotoxicity of Amikacin was less than kanamycin. 2) As the coincidental administration of antibiotics (kanamycin or Amikacin) and Na-alginate preparation was been done, acute renal failure was significantly produced. 3) Characteristic morphological finding of this acute renal failure were identified by necrosis of proximal convoluted tubular cells and in early stage the appearance of PAS positive. 4) In this results, the produced material by interaction of Amikacin and Na-alginate preparation increased the nephrotoxicity as same as kanamycin.

해결중심 집단미술치료의 운영 형태가 여고생의 몰입, 자기효능감, 문제해결력에 미치는 효과

최윤숙,최외선,김갑숙 한국미술치료학회 2011 美術治療硏究 Vol.18 No.4

In this study, a solution-focused group art therapy program was performed in an intensive program and a weekly program to examine the effects of the program on improving the flow, self-efficacy, and problem-solving skills of female high school students. The participants, first year students at a girl's high school were divided into three groups: 15 participating in the intensive program, 14 participating in the weekly program, and the control group of 15. A total of 8 sessions, which made 16 hours were offered to the participants in the intensive and weekly program. A flow test was administered to the participants in the programs at a second, fifth, and seventh session. A self-efficacy test and a problem-solving test were administered at a pre, post, and follow-up test. A scale instrument was administered at a second, fifth, and seventh session, and at the follow-up test. The control group received the self-efficacy and problem-solving test at the pre, post, and follow-up test. The data were computed for a one-way analysis of variance for homogeneity and two-way analysis of variance with repeated measures for the statistical analysis of inter-group and inter-test period differences in the participants' flow, self-efficacy, and problem-solving skills. The points of the scale instrument were presented on graphs. The findings of this study are as follows. First, solution-focused group art therapy was effective in improving the participants' flow: the intensive group showed higher improvement in flow. Second, solution-focused group art therapy was effective in improving the participants' self-efficacy: the intensive group showed higher improvement in self-efficacy. Third, solution-focused group art therapy was effective in improving the participants' problem-solving skills: the intensive group showed higher improvement in problem-solving skills. These findings show that solution-focused group art therapy was effective in improving the participants' flow, self-efficacy, and problem-solving skills, and that the intensive program was more effective than the weekly program. 본 연구는 여고생의 몰입, 자기효능감, 문제해결력의 향상을 위하여 해결중심 집단미술치료를 집중 과정과 주별 과정으로 실시하여 그 효과를 검증하고자 하였다. 연구대상은 인문계 여고 1학년생들로서 '자기성장을 위한 집단미술치료 프로그램'에 자발적으로 참여한 집중 과정 15명, 주별 과정 14명과 통제집단 15명으로 구성되었다. 집중 과정과 주별 과정에게는 총 8회기로 16시간의 해결중심 집단미술치료를 실시하였다. 연구도구는 2․5․7회기에 몰입 검사, 사전, 사후, 추후에 자기효능감과 문제해결력 검사, 2․5․7회기와 추후에 척도질문 검사를 실시하였다. 통제집단에게는 사전, 사후, 추후에 자기효능감과 문제해결력 검사만을 실시하였다. 자료분석은 사전검사의 동질성 검사를 위해 일원변량분석을 실시하였고 집단과 검사시기에 따른 몰입, 자기효능감, 문제해결력 수준을 분석하기 위해 검사시기를 반복측정변인으로 하는 이원변량분석을 실시하였으며 척도점수의 변화는 그래프로 제시하였다. 연구결과는 다음과 같다. 첫째, 해결중심 집단미술치료는 여고생의 몰입 향상에 효과적이었고 집중 과정의 효과가 더 높았다. 둘째, 해결중심 집단미술치료는 여고생의 자기효능감 향상에 효과적이었고 집중 과정의 효과가 더 높았다. 셋째, 해결중심 집단미술치료는 여고생의 문제해결력 향상에 효과적이고 집중 과정의 효과가 더 높았다. 따라서 해결중심 집단미술치료가 여고생의 몰입, 자기효능감, 문제해결력 향상에 효과가 있으며 집중 과정의 효과가 주별 과정보다 더 높다는 결론을 내릴 수 있다.

A case of back pain caused by Salmonella spondylitis -A case report-

최윤숙,조우진,윤소희,이성윤,박상현,박종국,장은희,신혜영 대한마취통증의학회 2010 Korean Journal of Anesthesiology Vol.59 No.-

Salmonella spondylitis is a rare illness, and it generally occurs in patients who have already had sickle cell anemia,and it is even rarer in patients who are without sickle cell anemia. A 61-year-old male patient was hospitalized for the evaluation of his renal function and then treatment was started for his back pain. His back pain had developed about 2 months previously without any specific trauma. Only a bulging disc was detected on the initial lumbar MRI. Regarding his fever, it was diagnosed as possible atypical pneumonia, scrub typhus, etc., and multiple antibiotic therapy was administered. At the time of transfer, the leucocytes and hs-CRP were normal and the ESR was elevated. A diagnostic epidural block was performed for his back pain, but his symptoms were not improved. Lumbar MRI was performed again and it showed findings of infective spondylitis. Salmonella D was identified on the abscess culture and so he was diagnosed as suffering from Salmonella spondylitis. After antibiotic treatment, his back pain was improved and the patient was able to walk.

단거리 스피드 스케이팅 선수의 복합 트레이닝 구성이 500m, 1000m 경기기록과 100m, 200m 출발구간기록에 미치는 영향

최윤숙,박해찬 한국자료분석학회 2016 Journal of the Korean Data Analysis Society Vol.18 No.4

본 연구는 순발력과 근력 향상에 비중을 둔 복합 트레이닝과 지구력과 근력 향상에 비중을 둔 복합 트레이닝이 단거리 스피드 스케이팅 경기력에 어떠한 영향을 미치는지 검토하였다. 본 연구의 대상은 고등학교 남성 단거리 스피드 스케이팅 선수이며, 집단은 지구력과 근력 중심의 복합 트레이닝을 실시하는 그룹(the group gave more focus on endurance and strength training; ESG, n=7), 순발력과 근력 중심의 복합 트레이닝을 실시하는 그룹(the group gave more focus on power and strength training; PSG, n=7)으로 구성하였다. 연구 대상자는 복합 트레이닝에 따른 경기 기록의 차이를 알아보기 위해 각 시즌 중 경기 기록을 측정하였다. 모든 연구 대상자는 500m, 1,000m 경기를 출전하였고, 시즌 중 공통적으로 출전한 3경기의 평균 기록과 3경기 중 최고기록을 측정하였다. 본 연구의 결과에서 500m, 1,000m의 평균기록과 최고기록은 두 그룹 모두 기록단축에 경향을 보였지만, 전반적으로 PSG가 높은 기록단축이 나타났다. 그리고 500m, 1,000m의 출발구간인 100m, 200m 평균기록과 최고기록은 두 그룹 모두 기록단축의 경향을 보였지만, ESG가 높은 기록단축이 나타났다. 따라서 본 연구에서는 파워와 근력 향상에 비중을 둔 트레이닝 방법이 지구력과 근력 향상에 비중을 둔 트레이닝 방법보다 500m, 1000m 기록 단축뿐만 아니라 500m, 1000m 출발구간기록인 100m, 200m 기록 단축도 더 효과적일 수 있다는 가능성을 제시 할 수 있었다. This study was to know the effects of short speed skating’s athletic performance by a group more focuses on endurance and strength training and a group more focuses on power and strength training. The subject was high school player and the group was consisted of a group more focuses on endurance and strength training group (ESG, n=7) and a group more focuses on power and strength training group (PSG, n=7). The subject measured competition records in each season to know the differences of records by complex training. The subjects entered a 500m and 1000m competition and then measured average record of 3 games and the best record of 3 games in the season. In the result of this study, both groups showed aspect of improvement in average and the best record of 500m and 1000m, meanwhile PSG showed more improvement in times. Both groups showed improvement in average and the best record of 100m, 200m, which is starting phase records of 500m, 1000m, meanwhile ESG showed more improvement in times. In conclusion, this study could suggest more focuses on power and strength training method (PSG) more than more focuses on endurance and strength training method (ESG) improved both 500m, 1000m records and also starting phase records of 500m, 1000m (100m, 200m records).

해결중섬 집단미술치료가 여고생의 스트레스 대처방식과 자존감에 미치는 효과

최윤숙,김갑숙 한국미술치료학회 2009 美術治療硏究 Vol.16 No.4

본 연 구는해 결중심 집단미술치료가여 고생의스 트 레스 대처방식과 자 존감에 미치는 효과를 알아보고자하 였다. 연 구 대 상은 인 문계 여고 1 학년 여학 생들로서 I스트레스 관리를 위한 집단미술치료 프로그램I에 자 발적으로 참여한 실험 집단 12명과 통제 집단 1 1명으로 구성되었다. 실험 집단에게는 총 8 회기의 해결중심 집단미술치료를 실시하였 으며 회기 당 120분이 소요되었다. 측정도구는 사전, 사후에 스트 레스 대처방식 검사r 자존감 검사/ 빗속의 사람 투사그림검사를 사용하였고 2회기,5회7],8 회기에 척도 질 문을 실시하여 그 점 수의변 화를 분석하였다. 자료분석은 스트 레스 대처방식과 자존감 접 수는 공변량 분석을, 빗속의사 람 검사는 t검증과 질적 분석을, 시기에 따른 척도 질 문 접 수변 화는 일원변량분석을/ 프로그램 회기 과정은 질적 분석을 실시하였다 연구 결과는 다음과 같다. 첫째/ 프로그램 적용 후에 실험 집단은 통제 집단에 비해 정서완화적 대처방식과 소망적 사고 대처방식을 많이 사용하였다. 둘째/ 빗속의사 람 검사에서 실험 집단의스 트 레스 대처능력이 통제집단보다 높아졌다. 셋째l 시기에 따른 척도 질 문 접 수가 긍정적으로 변화하였다. 넷째l 실험 집단은 통제 집단에 비해 자존감이 높아졌다. 이와 같은 결과를 통해 해결중심 집단미술치료가 여고생의스 트 레스 대처방식과 자 존감에 긍정적인 효과를미 친다는결 론을 내릴 수 있다. 깐us study is to leam the effects of solution-focused group 값t therapy on hi양1SChool 양1s' stre잃 coping style and self-esteem Study subjects are divided into the control group of eleven 뻐d 난le experimental group of twelve students, all selected from the first graders of a gir1s' hi양1 school who volunteered to participate in the therapy program. πle experim앙lt외 group received a tota1 of 8 야lerapy sessions, each lasting 120 ITUnutes. Measuring tools used are both pretest and pos야est of measuring the stress coping style, self-esteem and PITR pr이ection, together with an analysis of the score changes on the scaling questions φrected to the participants at 난le second, 짧남1 and ei양1바1 sessions. For data analysis, structural equation model is taken for stress coping styles and self-esteem, t-test and qu려itative an떠ysis for PITR, one-w야r random analysis for pretest and posttest scores, and qu머itative analysis for the progress of therapy sessions. πle results are as follows. First, the experimental group have become to use more of emotion-reducing coping style as well as hopeful-thinking coping style than the control group. Second, in PITR analysis, the experiment외 group scored hi양er on stress coping streng난15 than the control group. 돼뇨d, posttest scαes exhibits more positive effects on scaling questions than pretest scores. Fourth, the experimental group achieved hi양ler self-esteem than the control group. It can be concluded therefore that solution-focused group

Insulin effect on bupivacaine-induced cardiotoxicity in rabbits

최윤숙,이국현 대한마취통증의학회 2011 Korean Journal of Anesthesiology Vol.61 No.6

Background: Resuscitation following bupivacaine-induced cardiovascular collapse is difficult and often refractory to conventional treatment. This study was performed to assess the effect of insulin on bupivacaine-induced cardiovascular collapse in pentobarbital-anesthetized rabbits. Methods: Bupivacaine was administered at 0.75 mg/kg/min until the heart rate decreased to 65 beats/min. A bolus of regular insulin (2 U/kg) was administered intravenously at the bupivacaine infusion endpoint (BIE) in the insulin group (n = 8), and 2 mL of 0.9% NaCl was administered to the control group (n = 8). Results: All animals in the insulin group survived and four animals died in the control group. Arrythymia was rare 10minutes after the BIE in the insulin group. Conclusions: Bupivacaine-induced cardiovascular collapse can be effectively reversed with an insulin injection,probably through facilitation of cardiac conduction and contraction.