한국판 저장행동평가척도의 표준화 연구

이혜민,장진구,송후림,이수영,홍민하,김세주,김찬형,Lee, Hye Min,Chang, Jhin Goo,Song, Hoo Rim,Lee, Soo Young,Hong, Minha,Kim, Se Joo,Kim, Chan-Hyung 대한불안의학회 2021 대한불안의학회지 Vol.17 No.2

Objective : The Hoarding Rating Scale-Self-Report (HRS-SR) is a five-item scale that simply assesses the hoarding symptoms. We evaluated the factor structure, reliability, and validity of the Korean version of the HRS-SR (HRS-SR-K). Methods : A total of 144 individuals completed the self-administered questionnaires including HRS-SR-K, Obsessive-Compulsive Inventory-Revised-Korean version (OCI-R-K), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Psychometric properties of the HRS-SR-K were analyzed. Results : The Cronbach's α value for internal consistency of the HRS-SR-K was excellent (Cronbach's α=0.84). The construct validity was analyzed on the basis of principal component analysis and one-factor structure of the original scale was maintained. The HRS-SR-K total score and each item scores were more strongly correlated with the hoarding subscale score in OCI-R-K (convergent validity, r=0.71, p<0.01) than the corresponding scores of nonspecific depression or anxiety measures (discriminant validity). Conclusion : The HRS-SR-K is a simple and reliable self-report scale for examining the severity of hoarding symptoms.

회음 천공지 기저 도서형 피판을 이용한 회음부 재건

이혜민,김정태,황원중,Lee, Hae Min,Kim, Jeong Tae,Hwang, Weon Joong 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.1

Perineal area is composed of compact structures of urogenital organs and anus requiring a more sophisticated selection of flap and reconstruction. For achieving better outcome then conventional flap surgery, we use the perineal perforator based island flap for its reconstruction. After locating the perforator by Doppler, the flaps were designed according to the defect or expected vaginal orifice. The flaps were elevated bilaterally as island pattern. Finally defect or neovagina was reconstructed with inconspicious linear scar hidden in the inguinal crease. Five cases were performed with the perineal perforator based island flap. There were 3 cases of vulvar cancer, 1 case of transsexualism, and 1 case of ambiguous genitalia because of congenital adrenal hyperplasia. Operative results were satisfactory with good contouring and less prominent donor scar, when they were compared with other flap reconstructions such as latissimus dorsi perforator flap, groin flap, gracilis myocutaneous flap etc. The perineal perforator based island flap is highly recommended with the advantages of easy flap elevation, good rotation arc, and appropriate flap thickness for contouring. Compared with other conventional flaps, it can be selected as a good option for moderate defect of perineal area.

폐외 결핵에서 전혈 인터페론 감마 측정법의 진단적 유용성

이혜민 ( Hye Min Lee ),조성근 ( Sung Gun Cho ),강형구 ( Hyung Koo Kang ),박성운 ( Sung Woon Park ),이병욱 ( Byung Ook Lee ),이재희 ( Jae Hee Lee ),전은주 ( Eun Ju Jeon ),최재철 ( Jae Chol Choi ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.4

Background: The whole-blood interferon-gamma release assay (QuantiFERON-TB Gold [QFT-G]: Cellestis, Carnegie, Victoria, Australia) has been studied primarily for the use of diagnosing active pulmonary tuberculosis (TB) or latent TB. In the present study, the usefulness of QFT-G was evaluated for the diagnosis of extra-pulmonary tuberculosis (EP-TB). Methods: From June 2006 to February 2009, we evaluated the usefulness of QFT-G in patients (n=65) suspected with EP-TB, retrospectively. The diagnostic sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the QFT-G assay were analyzed. Results: EP-TB was diagnosed in 33 (51%) participants. The overall sensitivity, specificity, PPV, and NPV of the QFT-G assay for EP-TB were 78%, 79%, 81%, and 77%, respectively. Of the 33 with EP-TB, 14 (42%) were diagnosed with TB pleurisy, 7 (21%) with TB lymphadenitis, 7 (21%) with intestinal TB, and 5 (15%) with EP-TB in other sites. In subgroup analyses according by site of infection, the QFT-G showed 86% sensitivity, 64% specificity, and 78% NPV in TB pleurisy. On the other hand, the sensitivity, specificity, and NPV of the assay were 71%, 83% and 71%, respectively in TB lymphadenitis, and 86%, 100% and 88%, respectively in intestinal TB. Among the patients with suspected alternative site EP-TB, the sensitivity, specificity, and NPV of the assay were 50%, 80% and 67%, respectively. Conclusion: The QFT-G assay showed moderate diagnostic accuracy in EP-TB. However, negative QFT-G assay does not exclude EP-TB because of the low NPV of this assay.

한국산 꿀벌에서 Deformed Wing Virus의 발견과 Real-Time PCR 검출법의 확립

이혜민(Hye-Min Lee),이도부(Do-Bu Lee),한상훈(Sang-Hoon Han),이명렬(Myeong-Lyeol Lee),임윤규(Yoon-Kyu Lim),윤병수(Byoung-Su Yoon) 한국양봉학회 2005 韓國養蜂學會誌 Vol.20 No.2

임상적 아형 및 연령에 따른 선상태선의 임상 및 조직병리학적 고찰

이혜민 ( Hye Min Lee ),정경은 ( Kyung Eun Jung ),이혜경 ( Hye Kyung Lee ),구대원 ( Dae Won Koo ),이중선 ( Joong Sun Lee ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.9

Background: Lichen striatus is an uncommon, self-limiting, linear inflammatory disease occurring along the lines of Blaschko, mainly affecting children, and is diagnosed by clinical history and histopathological study of typical lesions. However, various aspects of the histopathologic findings have not yet been studied sufficiently. Objective: The aim of this study was to investigate the clinical and histopathologic characteristics of lichen striatus in Korea, according to age and clinical subtype. Methods: This retrospective study on lichen striatus was performed at our center; clinical and histopathologic findings from 32 patients were evaluated. Results: In all, 22 children and 10 adults were included. The lesions were predominantly distributed on the extremities (78.1%), including those that showed multiregional involvement. Twenty-four patients had erythematous papular lichen striatus (75%), and eight had hypopigmented macular type lesions (25%). All cases of hypopigmented macular subtypes had occurred in children. The histopathologic features of lichen striatus included basal vacuolar degeneration (93.3%), hyperkeratosis (83.3%), spongiosis (63.3%), and exocytosis of lymphocytes (63.3%) in the epidermis. Superficial and deep perivascular lymphocytic inflammatory infiltration (96.7%), lichenoid lymphohistiocytic infiltration (76.7%), and periappendageal involvement (53.3%) in the dermis were also observed. Papular lesions showed greater spongiosis, exocytosis, dyskeratosis, and vacuolar degeneration than hypopigmented lesions. Increased dyskeratosis and pigmentary incontinence as well as more severe lichenoid infiltration were observed in the adults. Conclusion: This study provides the first national data about the clinical and histopathologic characteristics of lichen striatus in adults and children. Some of the clinical and histopathologic characteristics differed according to the age group as well as clinical subtype. (Korean J Dermatol 2014;52(9):622∼630)

당뇨를 동반한 지속외래복막투석 환자에서 발생한 Neisseria sicca 복막염 1예

이혜민 ( Hyae Min Lee ),양인호 ( In Ho Yang ),이선희 ( Sun Hee Lee ),김선혜 ( Seon Hye Kim ),정다운 ( Da Wun Jeong ),정경환 ( Kyung Hwan Jeong ),이상호 ( Sang Ho Lee ),이태원 ( Tae Won Lee ),임천규 ( Chun Gyoo Ihm ),문주영 ( Ju Yo 전북대학교 의과학연구소 2014 全北醫大論文集 Vol.38 No.2

Neisseria sicca is a Gram-negative diplococcus found in the human oral mucosa and upper respiratory tract. Although colonization generally does not result in severe infection, some cases of infection have been reported, particularly in immunocompromised individuals. However, Neisseria sicca has not been reported as a pathogen of continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis in Korea. Here we describe a case of CAPD-related peritonitis due to Neisseria sicca in a patient with poorly controlled diabetes mellitus undergoing peritoneal dialysis.

Bevacizumab 사용 후 발생한 심한 허혈성 전대장염에서 대증적 요법으로 치료된

이하니 ( Ha Ni Lee ),이명아 ( Myung Ah Lee ),김상우 ( Sang Woo Kim ),임예지 ( Ye Jee Lim ),이화영 ( Hwa Young Lee ),이혜민 ( Hae Min Lee ),원혜성 ( Hye Sung Won ),전상훈 ( Sang Hoon Chun ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.1

Bevacizumab (Avastin(R)) is a monoclonal antibody against the vascular endothelial growth factor (VEGF) receptor that increases the overall survival rate when added to standard chemotherapy regimens in patients with metastatic colorectal cancer. The known toxicities of bevacizumab are hypertension, proteinuria, wound healing complications, arterial thrombosis, bleeding, and gastrointestinal complications. Especially ischemic colitis can rapidly develop into bowel perforation, so an emergency operation often is needed. Recently, a 65-year-old male patient developed ischemic pancolitis after FOLFOX (85 mg/m2 Oxaliplatin, d1; 200 mg/m2 Leucovorin, d1; 400 mg/m2 5-FU iv bolus, d1-2; and 600 mg/m2 5-FU, d1-2, every two wk) and Bevacizumab combination chemotherapy was administered. However, he recovered after early conservative care without surgery. We report this case with a review of literature. (Korean J Gastroenterol 2011;58:42-46)

혈구탐식성 림프조직구증이 동반된 성인형스틸병 1예

김광열 ( Kwang Yeol Kim ),최지영 ( Ji Young Choi ),이민혜 ( Min Hye Lee ),이정록 ( Jung Lok Lee ),양인호 ( In Ho Yang ),이혜민 ( Hyae Min Lee ),조영학 ( Young Hak Cho ),이유호 ( Yu Ho Lee ),이선희 ( Sun Hee Lee ),김동희 ( Dong Hee 전북대학교 의과학연구소 2014 全北醫大論文集 Vol.38 No.1

혈구탐식성 림프조직구증이 동반된 성인 형스틸병은 드물지만 치명적인 결과를 가져올 수 있기 때문에 조기에 병을 진단하고 일찍 적절한 치료를 시작하는 것이 중요하며 저자들은 골수천자 검사로 혈구탐식성 림프조직구증이 동반된 성인형스틸병 예를 경험하였기에 이에 문헌 고찰과 함께 보고하는 바이다. Adult-onset Still`s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. It is characterized by fever, skin rash, arthralgia, sore throat, hepatosplenomegaly, lymphadenopathy, leukocytosis, liver enzyme elevation, and high serum level of ferritin. Hemophagocyticlymphohistiocytosis is a rarerheumatic disease of life-threatening. Particularly, concomitant hemophagocyticlymphohistiocytosiswith AOSD could induce a fatal outcome. Thus it is important diagnos early and starttreatment. Here, we report a case of AOSD with concomitant hemophagocyticlymphohistiocytosis.

중세의 언어폭력으로서의 신성모독

이혜민 ( Hye Min Lee ) 한국서양중세사학회 2011 西洋中世史硏究 Vol.0 No.28

중세 시대에 신성모독(blasphemy)은 언어폭력의 한 형태로서 ``혀의 죄악`` 중 가장 극악한 죄악으로 인식되었다. 신성모독은 신이나 성모 마리아 성인성녀들에 대해 말이나 행동으로 모욕을 주는 행위를 말하며, 특히 13세기 이후에는 "불경죄(Lese-majesty)"의 개념과 결부되기 시작했다. 교황청에서 제시되고 발전한 이러한 새로운 개념은 14세기 이후 세속권력에 의해 "국왕모독죄"의 개념으로 발전하였다. 이에 따라 중세 후기에는 국왕이나 국왕의 대리인에 대한 폭력적인 언사의 사용을 국왕모독죄로 처벌하는 사례가 늘어났다. 한편, 13세기 이후부터는 신성모독의 언어적인 측면이 부각되어 중시되기 시작했는데, 이는 12세기 후반부터 발전한 "혀의 죄악"의 분류에 대한 스콜라적 논의에 바탕을 두고 있었다. 또한 같은 시기의 시각적인 이미지 자료들에서, "혀"라는 신체기관이 신성모독 혹은 언어적인 일탈을 상징하는 도상요소로서 강조되기 시작한다. 중세 후기에 들어서 신성모독 등 언어폭력을 저지른 죄인들에 대한 지옥의 처벌 장면이나 타락천사 도상 중 루시퍼의 타락과 그에 대한 단죄 장면 등 "혀"가 강조되는 이미지들이 많이 등장하게 되는 것은 이러한 역사적 맥락에서 기인하는 것이다.

중세와 르네상스 시대 기도서에 표현된 자연과 일상

이혜민 ( Lee Hye-min ) 이화사학연구소 2017 梨花史學硏究 Vol.0 No.54

Visual images of everyday life can be found abundantly in the medieval and Renaissance prayer books. It was only from the Late Middle Ages that concrete descriptions of daily life began to appear in the prayer books, especially in liturgical calendars. The earlier insertion of Labors of the Months in the prayer book`s calendar dates back to the mid-12th century. In fatc, while most prayer books of this period did not contain pictures, Labors of the Months along with zodiac signs began to appear on the calendar of Psalters from the mid-12th century. The calendar iconographical programmes created for royal and aristocratic clients visually expresses the division of roles between the lord and the peasant, while justifying the domination of the lord. This ideological orientation did not begin with the famous Les Tres Riches Heures of Duke of Berry, but was instead derived from the iconographical tradition from an earlier period. Prayer books with a new style emerged in the mid-13th century. These contain marginal ornaments called marginalia or drolerie. Within the marginal ornaments of these prayer books, such as Luttrell Psalter, we can identify a strange world combining everyday life and fantasy. Until the 13th century, however, the description of nature was not presented in detail in the manuscript paintings and ornaments, unlike Gothic sculptures. It was only from the 14th century that concrete and realistic descriptions of everyday life and of nature was brought into the illuminated prayer books. Later on, in the early 15th century, the famous Brother Limbourg combined the realistic landscape, person, and the description of everyday life. At the same time, the Labors of the Months in the calendar was repositioned from the margin to the center of page. In other words, the appearance of everyday work and entertainment has moved to the center of the screen and occupied a central position. These changes were influenced especially by the empiricism of the influence of ockemism. Two new trends appeared in the calendars of the Flemish prayer books at the end of the 15th century. While one is a sophisticated depiction of nature and still objects, and the other is a more vivid, colorful and various description of everyday life. In addition, as we can see in the case of the Grimani Breviary, the prayer books were also used as a medical guide. In other words, prayer books have become widely used not only as a medium for prayer, but also as a practical book used in the daily lives.