설하 신경 마비로 인한 설마비 환자 치험 1례

이재형,한성준,이엄지,이정은,남성욱,하나연,김진성,Lee, Jae-hyung,Han, Seong-jun,Lee, Eom-jee,Lee, Jung-eun,Nam, Seong-uk,Ha, Na-yeon,Kim, Jin-sung 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.5

Hypoglossal nerve palsy is an uncommon neurologic disorder. We report a 67-year-old Korean male with tongue paralysis due to hypoglossal nerve palsy. He had complaints associated only with tongue paralysis and was treated with herbal medicine and electric acupuncture for 12 days. We evaluated his tongue paralysis severity by a numeric rating scale (NRS) and the angle of tongue deviation. After 12 days of treatment, the NRS score showed improvement of his complaints, and the angle of tongue deviation was decreased. Korean medicine could therefore be an effective treatment choice for hypoglossal nerve palsy.

Genome sequence of Veillonella atypica KHUD-V1 isolated from a human subgingival dental plaque of periodontitis lesion

이재형,신승윤,이한,양석빈,장은영,류재인,이진용,문지회,Lee, Jae-Hyung,Shin, Seung-Yun,Lee, Han,Yang, Seok Bin,Jang, Eun-Young,Ryu, Jae-In,Lee, Jin-Yong,Moon, Ji-Hoi The Microbiological Society of Korea 2019 미생물학회지 Vol.55 No.1

본 논문에서는 한국인 만성 치주염 환자의 치은연하치태에서 분리된 Veillonella atypica KHUD-V1의 유전체 서열을 보고한다. 다른 V. atypica 균주와 달리, KHUD-V1에서는 프로 파지 및 이와 관련된 것으로 추정되는 여러 병독성 인자가 확인되었다. V. atypica KHUD-V1 균주 및 이 균주의 유전체 서열정보는 Veillonella의 유전체 다양성을 진화론적 관점에서 이해하고, V. atypica의 병독성 및 유전적 다양성에 기여하는 프로파지의 역할을 연구하는데 유용할 것이다. Here we report the genome sequence of Veillonella atypica strain KHUD-V1 isolated from subgingival dental plaque of Korean chronic periodontitis patients. Unlike other V. atypica strains, KHUD-V1 carries two prophage regions and prophage remnants, as well as several genes homologous to prophage-associated virulence factors, such as virulence-associated protein E, a Clp protease, and a toxin-antitoxin system. The isolate and its genome sequence obtained here will aid to understand the diversity of the genome architecture of Veillonella within an evolutionary framework and the role of prophages that contribute to the genetic diversity as well as the virulence of V. atypica.

Effective Concentration of Procaine Solution for Inotophoresis

이재형,김주형,제갈승주,Lee Jae-Hyoung,Kim Joo-Young,Jekal Seung-Joo The Korean Society of Physical Therapy 1998 대한물리치료학회지 Vol.10 No.1

The purpose of this study was to determine the of effective concentration of procaine iontophoresis for durarion of cutaneous local anesthesia. Forty-five healthy students with an age range of 19 to 34 years$(21\pm2.7)$, were participated in this study. The subjects were randomly assigned into 5 groups. Bach 9 subjects received iontophoresis on the flexor surface of dominant forearm with soft cotton pad $(3.5\times3.5cm)$ soaked in 2ml of $2\%$ (pH 5.28), $4\%$ (pH 5.12), $8\%$ (pH 4,98), $16\%$ (pH 4.72), $32\%$ (pH 4.52) procaine hydrochloride solution at 4mA for 10 minutes (total current 40mA min) using anodal direct current. The study was performed in a randomized, double-blind design, After procaine iontophoresis, the duration of anesthesia were evaluated at five minute intervals on five random locations in the iontophoretically area using a 21-gauge sterile hypodermic needle pressed with 1mm invagination unitl sharp pin-pricking pain sensation returned. The data were analyzed with one-way ANOVA to determine significant differences between groups. Duncan post hoc was performed at level .01. The relationship between anesthetic duration and procaine concentration was assessed with Pearson Product-Moment Correlation Coefficients. ANOVA tests showed significant differences in the anesthetic duration between the concentration of procaine solution (p<.001). Procaine iontophoresis with $4\%$ concentration produced cutaneous Socal anesthesia of significantly longer duration(15.56 min) than iontophoresis with $2\%,\;8\%,\;16\%$, and $32\%$ of procaine GCl(p<.01). Whereas the anesthetic duration had no correlation with concentration of procaine solution (r=-0.41, NS). These results support the $4\%$ procaine solution was an effective concentration of iontophoresis for induced cutaneous local anesthesia. 효율적으로 국소마취를 유발시키는 procaine이온도입의 효과적인 농도를 조사하였다. 19세에서 34까지의 자원자 45명을 9명씩 무작위로 5군으로 나누어 배치하고, 각군 대상자의 오른쪽 전완 전면에 각각 $2\% (pH\;5.2H),\;4%(pH\;5.12),\;8\%(pH\;4.98),\;16\%(pH\; 4.72),\;32\%(pH\;4.52)$ 염산 procaine용액 2ml를 적신 $3.5\times3.5 cm$의 면패드를 대고 4mA로 10분간 양극 직류전류를 통전시켰다. 이온도입 직후부터 5분 간격으로 21 G주사침으로 이온도입부위를 1mm함몰되게 눌러 바늘로 찌르는 통증을 느낄 때까지 감각검사를 시행하여 국소마취지속시간을 측정하였다. Procaine의 농도에 따른 축소마취지속시간을 일원분산분석한 결과 유의한 차이를 보였으며 (F=5.83; df=4, 40; p<.001). 이를 사후검정한 결과 농도 $4\%$의 국소마취지속시간이 농도 $2\%,\;8\%,\;16\%,\;32\%$보다 유의하게 길었다 (p<.01). 또한 상관분석 결과 약물의 농도는 국소마취지속시간과 상관관계가 없었다 (r=-0.41, NS). 본 연구 결과 $4\%$ 농도의 염산 procaine 용액의 이온도입이 국소마취지속시간을 가장 길게 유지하여 $4\%$ 염산 procaine 용액이 이온도입에 가장 효과적인 농도였음을 알 수 있었다.

전극배치가 Procaine 이온도입에 미치는 영향

이재형,송인영,국지연,Lee, Jae-Hyoung,Song, In-Young,Kook, Jee-Youn 대한물리치료과학회 1997 대한물리치료과학회지 Vol.4 No.2

The purpose of this study was to determine the efficacy of electrode placement on procaine iontophoresis. Thirty-three healthy students with an age range of 19 to 34 years, were participated in this study. The subjects were randomly assigned into 3 groups. Each subjects received iontophoresis on the proximal 1/3 of volar surface of dominant forearm with soft cotton pad($3.5{\times}3.5cm$) soaked in 2 ml of 4% procaine hydrochloride (pH 5.1) at 4 mA for 10 minutes(total current 40 mA min) of anodal DC. In transversal electrode placement(TEP) group, dispersive electrode was placed on the proximal 1/3 of dorsal surface of the forearm. In longitudinal electrode placement (LEP) group and control group, dispersive electrode were placed on the distal 1/3 of volar surface of the forearm. After procaine iontophoresis, duration of anesthesia were evaluated at five minutes intervals on five random locations in the iontophoretically area using a 21-gauge sterile hypodermic needle pressed with 1 mm invagination until return the sharp pin-pricking pain sensation. The data were ana lysed with one-way ANOVA to determine signific~nt differences between groups. The results showed significantly differences in the local anesthetic duration between the 3 groups(p<0.001). The anesthetic durations of TEP group and LEP group were significantly longer when compared with control group(p<0.05). Anesthetic durations of TEP group and LEP group were not significantly difference, but anesthetic duration of LEP group tends to longer than TEP group. In view of these results, clinicians should consider the electrode placement method when performing the iontophoresis.

선비의 벗 - 석창포(石菖蒲) 이야기

이재형,Lee, Jae-Hyeong 한국하천협회 2008 하천과 문화 Vol.4 No.2

CdZnS/CdTe 이종접합의 전기적 특성에 관한 연구

이재형,Lee, Jae-Hyeong 한국정보통신학회 2010 한국정보통신학회논문지 Vol.14 No.7

CdTe 및 Cu(In,Ga)$Se_2$ 박막 태양전지의 창층으로 널리 이용되는 CdS에서 Cd의 일부를 Zn으로 치환하면 두 물질 사이의 전자 친화력의 정합이 향상되고 에너지 밴드 갭이 증가하여 개방전압 및 광전류를 증가시킬 수 있다. 본 연구에서는 태양전지와 같은 광전소자에 적용되는 CdZnS와 CdTe로 구성되는 이종접합 소자를 제작하고 접합에서의 전류 전도기구를 조사하기 위해 온도에 따른 전류-전압 특성을 분석하였다. CdS/CdTe 접합의 전류 흐름은 계면 재결합과 터널링의 조합에 의해 조절되지만 CdZnS/CdTe 접합의 경우 상온 이상의 온도에서는 공핍층에서의 생성/재결합, 상온 이하의 온도에서는 누설 전류나 터널링에 의해 전류 흐름이 제한됨을 알 수 있었다. A CdS film has been used as a window layer in CdTe and Cu(In,Ga)$Se_2$ thin films solar cell. Partial substitution of Zn for Cd increases the photocurrent and the open-circuit voltage by providing a match in the electron affinities of the two materials and the higher band gap. In this paper, CdZnS/CdTe and CdS/CdTe heterojunctions were fabricated and the electrical characteristics were investigated. Current-voltage-temperature measurements showed that the current transport for CdS/CdTe heterojunction was controlled by both tunneling and interface recombination. However, CdZnS/CdTe heterojunction displayed different current transport mechanism with the operating temperature. For above room temperature, the current transport of device was generation/recombination in the depletion region and was the leakage current and/or tunneling in the range below room temperature.

간헐성 외사시에서 수술시기에 따른 수술결과 비교

이재형,강남여,Jae Hyung Lee,MD,Nam Yeo Kang,MD 대한안과학회 2013 대한안과학회지 Vol.54 No.2

Purpose: To investigate how the constancy of intermittent exotropia affects postoperative motor and sensory outcomes. Methods: A retrospective analysis was conducted of 44 patients with intermittent exotropia (IXT group) and 16 patients with constant exotropia with a previous history of intermittent exotropia (CXT group). All patients were followed up for more than 1 year postoperatively. Successful postoperative motor alignment was defined as within 8 prism diopters of exo- or esotropia at 6 meters and 33 centimeters. Successful sensory outcome (bifixation) was considered as stereoacuity ≤60 seconds of arc. The influence of constancy, age at surgery, duration of strabismus, preoperative gross stereopsis, preoperative distant deviation, and preoperative distant fusion to surgical outcomes were evaluated using logistic regression analysis. Results: Mean age at surgery and follow-up periods was 9.34 years and 37.8 months in the IXT group, and 10.19 years and 45.7 months in the CXT group. Successful motor alignment rates of the IXT and CXT groups were 65.9% and 48.3%, respectively. Postoperative bifixation rates of the IXT and CXT groups were 70.5% and 12.5%, respectively. The IXT group showed significantly better successful sensory outcome (p = 0.000), but no significant difference in motor outcome (p = 0.121). Constancy and preoperative distant fusion were associated with post-operative bifixation in univariate regression analysis (p = 0.001, 0.025, respectively). However, only the constancy was strongly associated with successful sensory outcome in multivariate regression analysis with an odds ratio of 20.138 (p = 0.008). Conclusions: Surgical correction of intermittent exotropia during the intermittent period showed better sensory outcome than in constant deviation period.

옥정호와 벼고을(동진강들)

이재형,Lee, Jae-Hyeong 한국하천협회 2006 하천과 문화 Vol.2 No.4

AlN/hBN 복합재료의 기계적 성질

이재형,안현욱,윤영식,조명우,조원승,Lee, Jaehyung,Ahn, Hyun-Wook,Yoon, Young-Sik,Cho, Myeong-Woo,Cho, Won-Seung 한국세라믹학회 2005 한국세라믹학회지 Vol.42 No.8

AlN-BN ceramic composites were fabricated and their mechanical properties were investigated. The relative density of hot-pressed composites decreased with increasing BN content, but over $99\%$ could be obtained with 30 $vol\%$ BN in AlN. YAG was formed in the composites and monolithic AlN as a second phase by the reaction between $Y_2O_3$, added as sintering aid, and $Al_2O_3$. As expected, Vickers hardness and Young's modulus decreased with increasing BN content. The three-point flexural strength also showed similar behavior decreasing from 500 MPa of monolith down to 250 MPa by the addition 30 $vol\%$ BN. However, interestingly, the standard deviation of the strength values decreased significantly as BN was added to AlN. As a result, the Weibull modulus of the AlN-30 $vol\% BN composite was 21.3, which was extremely high. Fractography and crack path studies revealed that BN platelets induced grain pull-out and crack bridging in a bigger scale during crack propagation. Consequently, fracture toughness increased as more BN was added, reaching 4.5 $MPa\sqrt{m}$ at 40 $vol\%$ BN.

2단계 추이모형에 의한 금강하구호의 공수도달시간의 평가

이재형,정만,Lee, Jae-Hyoung,Chung, Mahn 한국수자원학회 1993 물과 미래(한국수자원학회지) Vol.26 No.3

본 연구는 금강하구호의 운영정책을 효율적으로 수립할 수 있도록, 2단계 추이모형으로부터 저수지 정상분포와 공수도달시간을 평가하는 데 있다. 이를 위해서 저수량과 유량의 결합분포에 이산 Markov과정을 도입하였으며, 저수지 유입량 분포로는 이항분포를 이용하였다. 계산결과, 대청댐 건설이전인 1952년부터 1980년 유량자료로부터 갈수시 자기 상관계수의 도입에 따른 저수지 정상분포의 공수확률은 0.952에서 0.904로 감소하며, 대청댐 건설이후인 1981-1989년까지는 저수지 정상분포의 공수확률은 0.900에서 0.829로 감소하였다. 한편 평균공수도달시간은 초기 저수량이 1단위에서 댐건설전은 23일에서 37일로 증가하며, 건설후는 29일에서 61일로 증가하는 것으로 나타났다. 이는 비교적 용량이 적은 금강하구호에서 저수율이 낮을 때 정상분포, 공수도달시간 등이 저수지 유입량의 자기상관계수에 따라 변화함을 알 수 있다. 따라서 갈수시 감강하구호의 효율적인 이수관리를 위해서는 유입량의 자기상관성을 고려해야 한다. This study aims at the evaluation of the stationary distribution and the emptiness passage time for the effectiveness of water utility in the Keumgang estuary reservoir by two-step transition model. It was taken discrete Markovian correlated inflows for the joint probability of inflows and storage, and was used binomial distribution for inflows distribution. As the results, it was decreased from 0.952 to 0.904 the emptiness probability of the reservoir stationary distribution during 1952-1980, and from 0.900 to 0.829 during 1981-1989, and the average emptiness passage time was increased from 23 days to 37 days during 1952-1980, and from 29 days to 61 days during 1981-1989 at low state of storage. From this, it is found that the emptiness passage time is varied with the increase of the inflows auto-correlation coefficient in the Keumgang estuary reservoir. Therefore, it is understood that auto-correlation coefficient must be taken into consideration for the evaluation of water utility in a small reservoir at drought time.