In vivo와 in vitro 에서 양극산화 처리한 타이타늄 시편의 상대적인 생체적합성 평가

이유미,이은정,염동선,김도순,이성태,김병일,조현욱,Lee Yu-Mi,Lee Eun-Jung,Yeom Dong-Sun,Kim Do-Soon,Yee Sung-Tae,Kim Byung-Il,Cho Hyun-Wook 한국생명과학회 2006 생명과학회지 Vol.16 No.2

처리하지 않은 타이타늄과 양극 산화 처리한 타이타늄 시편의 생체적합성을 평가하기 위해, 시편을 마우스의 복부 피하 조직에 이식하고 2주 동안 생존시켰다. 그 시편에 대한 복부 피하 결합조직의 반응을 조직학적으로 조사하였다. 시편 주위를 둘러싸는 섬유성 결합조직 막이 관찰되었으며 이 막은 섬유모세포, 섬유세포 및 기타 세포로서 중성호성백혈구, 대식세포, 거대다핵세포 등으로 이루어져 있었다. 시편을 둘러싸는 이 막에 새로이 형성된 혈관이 존재하기도 하였다. 임플란트와 접하는 섬유성 막에 거대다핵세포가 관찰되었다. 섬유성 막에 있는 세포 종류와 막의 두께를 조사하였다. 막에 있는 대부분의 세포는 섬유모세포와 섬유세포이었다. 양극 산화 처리를 하지 않은 타이타늄 시편에 비해 산화 처리를 한 시편을 둘러싸는 섬유성 막의 평균 두께가 더 얇았다. 또한 타이타늄 시편의 생체적합성을 세포 배양법으로 조사하였다. 산화 처리를 한 시편 위에서 배양한 MG-63 세포의 수가 유의하게 증가되었다. 이런 결과들은 in vivo 와 in vitro 실험에서 산화 처리를 한 타이타늄 시편이 생체적합성을 증가시키는데 효과적이라는 것을 말해준다. To evaluate the biocompatibility of untreated and anodized titanium specimens, the specimens were implanted in the subcutaneous tissue of the abdominal region of female mice for two weeks. The reaction of connective tissue to specimens was histologically studied. The implants were encapsulated by fibrous connective. tissue consisting of fibroblast, fibrocyte and other cellss including neutroophil, macrophage and giant multinucleated cell. some newly formed blood vessels were located in the fibrous capsule surrounding the implant. Giant multinucleated cells were observed at the fibrous capsule adjacent to the implant. Kind of cell types and the thickness of fibrous capsules were examined quantitatively. Most of cell types located in the fibrous capsule were fibroblast and fibrocyte. The average thickness of fibrous capsules for the anodized specimens was much thinner than that of the untreated titanium specimen. Biocompatibility of titanium specimens were also studied by using cell culture method. The number of MG-63 cells was significantly increased on the anodized titanium specimens in vitro experiment. Our observations suggest that anodized titanium specimens are more effective for the improvement of biocompatibility in vivo and in vitro.

산림경영 - 산림정보

이유미,Lee, Yu-Mi 한국산림경영인협회 2012 山林經營 Vol.204 No.-

수면의 질과 구강 안면 통증의 관계

이유미,Lee, You-Mee 대한안면통증구강내과학회 2006 Journal of Oral Medicine and Pain Vol.31 No.1

This study was performed to investigate about sleep quality and orofacial pain pattern between experimental and control group. 101 subjects with temporomandibular disorders without any psychologic and neurologic problem were selected from the patients presented to Wonkwang University dental hospital. Routine clinical examination for TMD was carried out, especially for the frequency of headache and the craniocervical muscles were also done by the author in the first visit. All the subjects filled out the questionnaires, that was, for the evaluation of sleep quality using Pittsburgh sleep quality index(PSQI), and for the analysis of behavioral pain scale questionnaires. Data obtained were statistically processed by the SPSS Windows program and the results of this study were as follows: 1. Subjective sleep index, sleep latency, sleep disturbance, global score in control group were significantly lower than 2. Subjective sleep index, sleep disturbance, global score in subject with headache were significantly lower than subject without headache(P<0.05). 3. Medicine taker have sleeping drug. Caffeine drinkers was significantly higher in daytime dysfunction, global score than no drinker. 4. It have more frequent head and neck pain, pain spreading, daily life difficult in poor sleeper than good sleeper.

책갈피산책 - "욕망의 식물학"

이유미,Lee, Yu-Mi 대한출판문화협회 2002 출판저널 Vol.319 No.-

익수영진고가미방의 지황박, 복령피 배합과 발효에 따른 제제가 면역활성에 미치는 영향

이유미,김왕인,최동희,김미래,문양선,김지은,윤대환,손홍석,나창수,Lee, Yu-Mi,Kim, Wang-In,Choi, Dong-Hee,Kim, Mi-Rae,Moon, Yang-Seon,Kim, Ji-Eun,Youn, Dae-Hwan,Son, Hong-Seok,Na, Chang-Su 대한한의학방제학회 2018 大韓韓醫學方劑學會誌 Vol.26 No.1

Objectives : This study was carried out to enhance the activity of Iksuyoungjingo, which has the tonify Qi, nourish Yin effect of oriental medicine, and to study the effect of the prescriptions on the immunological activities. Methods : Immunosuppression was induced by methotrexate (MTX) 2 mg / kg, the experimental group was divided into IYGgami-I, IYGgami-I-F, IYGgami-II and IYGgami-II-F groups. Each prescription was administered with drinking water for 20 days, and body weight was measured every 5 days during this period. Leukocyte, $TNF-{\alpha}$, IL-2, IL-6, IgE, spleen weight and body weight were measured Results : In the changes of $TNF-{\alpha}$, IL-2 and IL-6 as pro-inflammatory elements, all of the experimental groups showed a significant increase compared to the control group. In the IgE changes, the IYGgami-I-F, IYGgami-II and IYGgami-II-F groups showed a significant decrease compared to the control group. In the changes of spleen weight, the IYGgami-II-F group showed a significant increase compared to the control group. In the changes of WBC and lymphocytes, the IYGgami-I-F group showed a significant increase compared to the control group. Conclusions : From the above results, it can be observed that the efficacy against immunity is exerted in all of the preparations, and it was confirmed that the efficacy was maintained constant even when utilizing the Rehmannia glutinosa Residue and Poria cocos Bark, and that a more beneficial effect can be exerted in the effectiveness when the fermentation is carried out.

산림경영: 산림정보 -층층이 달린 꽃송이 따라 은은한 향기

이유미,Lee, Yu-Mi 한국산림경영인협회 2011 山林經營 Vol.199 No.-

한국형 가정보육시설의 디자인지침 개발을 위한 이론적 고찰

이유미(You-Mi Lee),김미희(Mi-Hee Kim) 전남대학교 생활과학연구소 2005 生活科學硏究 Vol.15 No.-

Family day care centers in apartment complexes, which are popular in Korea, have merits as day care centers for young children due to their homey environments, closeness to children’s homes, and available outdoor playgrounds utilizing open space in the complexes. Thus, there is a great potential to develop a design guideline for family day care in apartments which are in demand now. The purpose of this study is to provide basic information for developing a design guideline for family day care centers. Therefore, this study aimed to investigate the important issues that influence the development of design family day care center. These issues are environment behavior. Murtha & Lee’s User Benefit Criteria, and Pattern theory. As a result, this study provides basic data for developing a design guideline for family day care and as a base for the next study.

공동주택단지에서의 범죄피해경험율과 범죄로부터의 안전성(safety) 평가 지표간의 상관성 분석에 관한 연구

이유미,Lee, You-Mi 한국주거학회 2008 한국주거학회 논문집 Vol.19 No.2

The purpose of this paper is to analyze the correlation analysis between the experienced crime victimization rate and the evaluation indicator of residents' safety of outdoor spaces from crime in multi-family housing. Additionally this paper intend to analyze the correlation analysis between the residents' satisfaction about safety and the evaluation indicator of residents' safety of outdoor spaces. For that purpose, 9 Multi-Family Housing located in the metropolitan area were selected to perform a survey against 349 residents during May 26-29, 2006. The SPSS program was used and the level of satisfaction ranged from 1 to 5. Scale of 5 being most satisfied while 1 being most dissatisfied. The results of this study are the followings; 1) Most occurred crime were auto theft and damages, poster matter theft, housebreaking. 2) The crime rate is higher in outdoor than in indoor. 3) This study proved the correlation between the residents' satisfaction about housing safety and most indicators except the number of households etc. 4) By the results of the correlation coefficient it makes clear that the number of apartment building, the visibility of Green Space, the location of pedestrian etc. have relation with the residents' satisfaction about housing safety.

인텔리전트아파트 시스템에 대한 수요자 그룹별 요구 분석 연구

이유미,임미숙,김석경,Lee, You-Mi,Yim, Mi-Sook,Kim, Suk-Kyung 한국주거학회 2007 한국주거학회 논문집 Vol.18 No.5

This study aimed to analyze residential demands on intelligent systems for apartments and suggest space design directions of intelligent apartment complexes. Data collection was done through mail-in surveys by five respondent groups. Outcomes of this study would provide basic data for developing intelligent apartment housing corresponding to the residential characteristics and demands of the five respondent groups. The sample size for the questionnaire survey was 592. The types of the target residents in this study were classified into five categories; nuclear families, dual income families, single households and the handicapped needing special environmental supports, and workers at home who need the new home design with a home office. The primary findings of this study were as follows. 1) For the controllers of intelligent system, nuclear families preferred TV, single households prefer home-pad which is movable and provides access to the internet. Dual income families, the handicapped and workers at home preferred remote control panels. 2) For the desirable space for computer equipment, regardless of the types of target residents, bedroom and living room were preferred. 3) For the desirable space for a home theater system, most of respondent groups preferred living rooms, but many rather wanted to have media rooms only for this system.

우리나라 단독주택의 건물배치와 외부공간계획 특성에 관한 연구

이유미,Lee You-Mi 한국주거학회 2006 한국주거학회 논문집 Vol.17 No.2

This study aims to analyze exterior spatial characteristics of the detached houses in Korea which were designed by professional architects. For this, plans, pictures and data of 113 houses which appeared in architectural publications from July 1998 to June 2002 were collected and analyzed. The results of the study are like this. 1) For the shape of buildings, the number of the non-rectangular shaped buildings is higher than that of the rectangular shaped ones. ; 2) For the location of exterior gardens, the number of the houses with front gardens is higher than that of the houses with back gardens. The exterior gardens are mostly accessed from the living rooms. 3) For the interior gardens, 50% of the surveyed houses have this type of gardens. They are mostly located at the back of the living rooms. The interior gardens are mostly accessed from the living rooms, dining rooms and corridors respectively. 4) For the terraces which are located in the 1st floor, they are mostly accessed from the living rooms. : 5) For the balconies which are located in the 2nd floor, they are mostly accessed from the bedrooms.; 6) For the location of the entrances, they are mostly located in the front side of the buildings and mostly facing south.