청송 달기약수의 수질특성에 관한 연구

이성호,Lee, Sung-Ho 대한화학회 2000 대한화학회지 Vol.44 No.3

청송 달기약수(상탕,중탕,하탕)의 수질특성을 파악하기 위해 1999년 5월부터 2000년 2월까지 약 1년 동안 계절별로 총 28개 항목의 함유성분을 분석하여 다음과 같은 결론을 얻었다. 각 탕별 약수의 수질에 큰 차이가 있었다. 하탕약수는 Mg과 Na이 상대적으로 높았?만? 중탕약수는 Ca, K, Si, Fe, Mn, 전기전도도, 총염기도, DO, $Cl^-$, $SO_4^{2-}$등에서 상대적으로 높은 값을 보였다. 건강상 유해성분인 As, Cd, $Cr^{6+}$, Hg는 검출되지 않았으며, Pb는 기준이하로 나타났다. 먹는물 수질기준을 초과한 항목으로는 경도, Fe와 Mn이었다. 그러나 샘물의 경우에는 이 기준을 적용하지 아니한다고 규정하였다. 약수의 계절별 특징으로는 온도를 제외한 기타 항목에서는 뚜렷한 차이가 없었다. 음용수에서 섭취할 수 있는 미네랄 양을 알아보고자 미국 국립과학아카데미의 하루 요구허용량과 섭취 음용수의 양을 1.O L로 하고 購종善嗤?기준으로 계산한 결과, Ca 35.05%, Mg 36.43%, Na 5.88∼10.63%, K 0.19∼0.57%, Mn 21.86∼43.72%, Zn 0.65%, Cr,Cu, P 등은 0.01% 이하이고, Fe는 95.1%이었다. 따라서 달기약수는 철분이 풍부한 약수임을 알 수 있었다.달기약수는 K index가 111.7∼254.6,O index가 2.3∼4.5로서 Hashimoto가 주장한 K index 5.2,O index 2.O을 상회하므로 건강에 좋고 맛있는 물의 조건을 만족하고 있다. This study deals with the water qualities of Dalgi mineral spring in Cheongsong district.Water samples which were taken from upper, middle and bottorn spring sites were tested for twenty eight important water quality items including minerals, essential and/or toxic trace elements, and the analytical items to affect the taste of mineral water, seasonally from May 1999 to February 2000 The results obtained wereas follows:Each spring site showed much difference in major items. Bottom spring water showed higher value of Mg and Na than others. Middle spring water showed the highest value in all of the items except Mg and Na. The concentration of Hardness, Fe and Mn in mineral water were over than the normal standard for drinking water, but these items are not specified for the mineral water. As, Cd, $Cr^{6+}$ and Hg were not found and Pb was found ln trace level. All of the items proved nearly constant during the four seasons except water temperature. The contribution of mineral water to the nutrition of human was calculated in order to investigate the health effect of drinking water on the bases of Required Daily Allowance,one liter of water drinking and the mineral concentration of the bottom spring. The percentage of consumable minerals of Ca, Mg, Na, K, Mn,Zn and Fe were 35.05,36.43,5.88∼10.63,0.19∼0.57,21.86∼43.72,0.65, and 95.l respectively. This means Dalgl mineral water is pIenty of iron mineral. The K and O indexes of mineraI water appeared to be good for healthy and delicious water.

청송약수의 탄산과 유해 가능성 물질 존재에 관한 연구

이성호,Lee, Sung-Ho 한국식품영양학회 2021 韓國食品營養學會誌 Vol.34 No.1

The purpose of this study is to measure the levels of eluted and dissolved CO2, and CO, volatile organic substances and radiation composition of Cheongsong mineral water which were collected from November 2019 to July 2020 during the autumn, spring, and summer seasons at collection points located in the upper, middle and lower spring waters. Data of the upper, middle and lower spring waters include the following: the amount of eluted water (average value±standard deviation, mL/min) was 30.07±0.52, 15.03±0.16, 23.73±0.42, and the amount of CO2 gas was 1,000 ppm or more. In addition, there was no detection of CO or total volatile organic substances (TVOC) and the radiation dose was 0.08 to 0.13. μSv/h. A blank test value of 0.08 to 0.10 μSv/h, when compared with the median value, showed a high value of 0.02 μSv/h, and the uranium test results provided by the Cheongsong-gun Office were 0.0118 mg/L (date 2019.06.18) and 0.0091 mg/L (date 2020.06.04.) respectively, which was less than the permission limit of 0.03 mg/L. However, it is believed that further research using more precise devices is needed in order to guarantee the safety and health of the water.

흰쥐 자궁과 부정소에서의 Luteinizing Hormone (LH) 유전자 발현

이성호,이영기,Lee, Sung-Ho,Lee, Young-Ki 대한생식의학회 1999 Clinical and Experimental Reproductive Medicine Vol.26 No.2

Recent studies clearly demonstrated that the novel expression of LH gene in the rat testis, and suggested the local action of the LH-like molecule. The present study was performed to analyze the expression of LH genes in the rat accessory reproductive organs. Expression of LH subunit genes in the rat uterus and epididymis was demonstrated by reverse transcription-polymerase chain reaction (RT-PCR) and specific LH radioimmunoassay (RIA). The $LH_{beta}$ transcripts in these organs contained the published cDNA structure, the pituitary type exons 1-3, which encoded the entire $LH_{beta}$ polypeptide. Presence of the transcripts for the ${\alpha}$-subunit in the rat reproductive tissues were also confirmed by RT-PCR. In the LH RIA, significant levels of LH were detected in crude extracts from the rat ovary, uterus and epididymis. The competition curves with increasing amount of tissue extracts were parallel with those of standard peptide, indicating that the immunoreactive LH-like materials in these tissues are similar to authentic pituitary LH molecule. In rat epididymis, the highest amount of immunoreactive LH was detected in corpus area. Our findings demonstrated that the genes for LH subunits are expressed in the rat accessory reproductive organs, and suggested that these extrapituitary LH may act as a local regulator with auto and/or paracrine manner.

감육배관의 건전성평가 및 정비 관련 기술기준 고찰

이성호,이요섭,김홍덕,이경수,황경모,Lee, Sung Ho,Lee, Yo Seob,Kim, Hong Deok,Lee, Kyoung Soo,Hwang, Kyeong Mo 한국압력기기공학회 2015 한국압력기기공학회 논문집 Vol.11 No.2

Local wall thinning and integrity degradation caused by several mechanisms, such as flow accelerated corrosion, cavitation, flashing and/or liquid droplet impingement, is a main concern in secondary steam cycle piping system of nuclear power plants in terms of safety and operability. Thinned pipe management program (TPMP) has being developed and optimized to reduce the possibility of unplanned shutdown and/or power reduction due to pipe failure caused by wall thinning. In this paper, newest technologies, standards and regulations related to the integrity assessment, repair and replacement of thinned pipe component are reviewed. And technical improvement items in TPMP to secure the reliability and effectiveness are also presented.

나트륨 섭취량 추정을 위한 소변 중 Cl^-의 간이적 측정방법의 유용성 검증

이성호,이채준,주성미,이현주,라왕연,김순옥,Lee, Sung-Ho,Lee, Chae-Joon,Ju, Sung-Mi,Lee, Hyun-Joo,Ra, Wang-Yeon,Kim, Soon-Ok 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.1

The purpose of this study was to measure concentrations of $K^+$, $Na^+$, $Cl^-$ by ionometer with check salt strip, simple salimeter and Ion-selective electrode (ISE) and compare the results of each mensuration; furthermore, the possibility of inferring the $Na^+$ concentration from $Cl^-$ concentration of urine and the impact of $K^+$ on the concentration of each ion was examined. The results showed that ISE determined $Na^+$ and $Cl^-$ concentrations in the urine are highly interrelated (R=0.9039); in addition, concentrations of $Cl^-$, measured with strip and ISE from urine are highly interrelated (R=0.9338). The concentration of $Na^+$ in urine, inferred by measuring $Cl^-$ concentration with strip, has a high relationship (R=0.8580) with the concentration of $Na^+$ in urine, measured by ISE. The results of our study will increase awareness of $Na^+$ intake and the utility of check salt strip, as well as the possibility of inferred $Na^+$ concentration from measures of $Cl^-$ concentration as a screening test for reducing sodium intake.

KASINICS 광학계의 고스트 분석

이성호,육인수,진호,박수종,한정열,이대희,공경남,조승현,박영식,박장현,한원용,Lee, Sung-Ho,Yuk, In-Soo,Jin, Ho,Pak, Soo-Jong,Han, Jeong-Yeol,Lee, Dae-Hee,Kong, Kyung-Nam,Cho, Seung-Hyun,Park, Young-Sik,Park, Jang-Hyun,Han, Won-Yong 한국천문학회 2005 天文學論叢 Vol.20 No.1

The reimaging optics of the KASINICS (KASI Near Infrared Camera System) includes many transparent components like an entrance window, band-pass filters, and blocking filters. As observational targets or in-field background objects, bright stars may cause optical ghosts that can significantly degrade the system performance of the KASINICS. We estimated analytically the relative brightness of ghost components with respect to a point source and examined the effects of tilting optical components as a method of suppressing ghosts. We also performed numerical ray tracings including all the optical components and found the results are consistent with those of the analytic estimations. We conclude that the KASINICS will not suffer from significant ghost effects with appropriate anti-reflection coatings and fittings for the optical components.

벤처기업의 지식중심문화의 영향에 관한 연구

이성호,Lee, Sung-Ho 한국벤처창업학회 2012 벤처창업연구 Vol.7 No.1

본 연구는 벤처기업의 성과를 제고시키기 위하여 지식경영에 대한 지식중심문화와 협동학습의 영향을 파악하고자 문헌연구와 실증분석을 수행하였다. 지식이 경쟁우위의 핵심역량이 되어 가고 있는 지식경제하에서 기업 조직 성공의 관건은 지식경영을 선도할 구성원들의 자율성과 풍토가 마련된 가운데 효율적인 학습을 위한 협동적 분위기가 적실히 요구되고 있다. 실증분석 결과는 지식중심문화의 자율성과 조직풍토가 성과에 영향을 미칠 때 협동학습의 조절효과가 없었으며, 규모별 비교에서 중소벤처기업의 경우에는 조절변수인 협동학습이 성과에 유의적인 영향을 미치고 있었고, 대벤처기업의 경우에는 조절변수인 협동학습이 성과에 유의적인 영향을 미치고 있었으며, 조직풍토는 유의적인 영향을 미치고 있는 것으로 나타났다. This paper analyzes the relationships between knowledge-centered culture, learning process, and knowledge/learning outcomes. Knowledge management researches have emphasized the important role of a knowledge-centered culture in venture business. After a literature review, research model is developed and the research hypothesis is made. And then, the hypothesis is tested using regression analysis with data collected from venture firms. The results of the empirical study show that cooperative learning does not strengthen the knowledge outcomes on the autonomy and organizational climate of knowledge-centered culture.

Lee's 메뉴엔지니어링 분석법(LME)의 적용 - 이탈리아 피자류를 중심으로 -

이성호,Lee, Sung-Ho 한국식품영양학회 2020 韓國食品營養學會誌 Vol.33 No.1

The purpose of this study is an application of Lee's Menu Engineering (LME) method for menu analysis on the eight kinds of pizza selected from 17 kinds of pizza served by an Italian restaurant near by the Keimyung College University campus. The eliminated nine items were in the third quadrant or below the trend line. The LME method is more efficient than generally used methods such as the Miller, Kasavana & Smith, Uman, Pavesic and Merricks & Jones method. The LME method comprises reference lines and four quadrants created by x, y axes and its average values. The x and y axes comprise the sales ratio (MM%, percentage of the Menu Mix) and the weighted contribution margin (WCM%, percentage of the Weighted Contribution Margin) respectively. The obtained results are such that total sales increased by 1.59% from 58,747,200 won to 59,684,000 won, despite the decrease in sales volume. Total contribution margin also increased from 35,248,320 won to 35,810,400 won. The trend line also shows from y=0.9147x (R²=0.703) to y=0.9944x (R²=0.9893). These results indicate that the LME method is superior in practical applications.

흰쥐의 시상하부외 지역에서의 Growth Hormone Releasing Hormone (GHRH) 유전자발현;뇌하수체내 국부인자로서 Lactotroph분화에 관여할 가능성에 대하여

이성호,Lee, Sung-Ho 대한생식의학회 1996 Clinical and Experimental Reproductive Medicine Vol.23 No.3

Biosynthesis and secretion of anterior pituitary hormones are under the control of specific hypothalamic stimulatory and inhibitory factors. Among them, Growth Hormone Releasing Hormone (GHRH) is the major stimulator of pituitary somatotrophs activating GH gene expression and secretion. Human GHRH is a polypeptide of 44 amino acids initially isolated from pancreatic tumors, and the gene for the hypothalamic form of GHRH is organized into 5 exons spanning over 10 kilobases (kb) on genomic DNA and encodes a messenger RNA of 700-750 nucleotides. Several neuropeptides classically associated with the hypothalamus have been found in the extrahypothalamic regions, suggesting the existence of novel sources, targets and functions. GHRH-like immunoreactivity has been found in several peripheral sites, including placenta, testis, and ovary, indicating that GHRH may also have regulatory roles in peripheral reproductive organs. Furthermore, higher molecular weight forms of the GHRH transcripts were identified from these organs (1.75 kb in testis; 1.75 and >3 kb in ovary). These tissue-specific expression of GHRH gene suggest the existence of unique regulatory mechanism of GHRH expression and function in these organs. In fact, placenta-specific and testis-specific promoters for GHRH transcripts which are located in about 10 kb upstream region of hypothalamic promoter were reported. The use of unique promoters in extrahypothalamic sites could be refered in a different control of GHRH gene and different functions of the translated products in these tissues. Somatotrophs and lactotrophs have been thought to be derived from a common bipotential progenitor, the somatolactotrophs, which give origins to either phenotypes. Although the precise mechanism responsible for the lactotroph differentiation in the anterior pituitary gland has not been yet clalified, there are several candidators for the generation of lactotrophs. In human, the presence of GHRH peptides with different size from authentic hypothalamic form in the normal anterior pituitary and several types of adenoma were demonstrated. Recently our group found the existence of immunoreactive GHRH and its transcript from the normal rat anterior pituitary (gonadotroph> somatotroph> lactotroph), and the GHRH treatment evoked the increased proliferation rate of anterior pituitary cells in vitro. The transgenic mouse models clearly shown that GHRH or NGF overexpression by anterior pituitary cells induced development of pituitary hyperplasia and adenomas particularly GH-oma and prolactinoma. Taken together, we hypothesize that the pituitary GHRH could serve not only as a modulator of hormone secretion but as a paracrine or autocrine regulator of anterior pituitary cell proliferation and differentiation. Interestingly enough, the expression of Pit-1 homeobox gene (the POU class transcription factor) was confined to somatotrophs, lactotrophs and somatolactotrophs in which GHRH receptors are expressed commonly. Concerning the mechanism of somatolactotroph and lactotroph differentiation in the anterior pituitary, we have focused following two possibilities; (1) changes in the relative levels or interactions of both hypothalamic and intrapituitary factors such as dopamine, VIP, somatostatin, NGF and GHRH; (2) alterations of GHRH-GHRH receptor signaling and Pit-1 activity may be the cause of lactotroph differentiation or pituitary hyperplasia and adenoma formation. Extensive further studies will be necessary to solve these complicated questions.

고준위폐기물 처분장 안전성평가 관련 타 국가의 기술기준

이성호,황용수,Lee, Sung-Ho,Hwang, Yong-Soo 한국방사성폐기물학회 2009 방사성폐기물학회지 Vol.7 No.3

The basic function of HLW disposal system is to prevent excessive radio-nuclides being leaked from the repository in a short time. To do this, many technical standards should be developed and established on the components of disposal system. Safety assessment of a repository is considered as one of technical standards, because it produces quantitative results of the future evolution of a repository based on a reasonably simplified model. In this paper, we investigated other countries' regulations related to safely assessment focused on the assessment period, radiation dose limits and uncertainties of the assessment. Especially, in the investigation process of the USA regulations, the USA regulatory bodies' approach to assessment period and peak dose is worth taking into account in case of a conflict between peak dose from safety assessment and limited value in regulation.