MOCVD 에 의한 BN 박막 제조

이상열,이중기,남영우,박달근 ( Sang Yeol Lee,Joong Kee Lee,Young Woo Nam,Dalkeun Park ) 한국화학공학회 1996 화학공학의이론과응용 Vol.2 No.1

소 위의 Phosphoinositide - specific Phospholipase C Isozymes 에 관한 연구

이상열,문경호,이기영 ( Sang Yeol Lee,Kyung Ho Moon,Kee Young Lee ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.4

Expression of multiple PLC isozymes was studied in bovine stomach of rumen, reticulum, omasum and abomasum. The soluble protein of stomach homogenates was resolved on a DEAE column using high performance liquid chromatography. The PLC enzymes from the stomach of rumen, reticulum, omasum and abomasum were eluted from the DEAE-column at 26-30 min and 41-46 min. Comparing the retension times of stomach PLC enzymes with those of bovine brain PLC isozymes, the PLC in the first and second peak might be corresponded to PLC δ and either of PLC β or γ respectively. This result was clearly confirmed by monoclonal antibodies derived against PLC β, γ and δ of bovine brain. In immunoblot analysis, PLC in the first activity peak from bovine stomach was blotted only with the antibody against PLCδ, and the second peak PLC was reacted with the antibodies against both PLC β and γ, which showed that the second peak contained both PLC β and γ. Using monoclonal antibodies which bind to different epitopes on the same enzyme, tandem radioimmunoassay was performed for quantitating the amounts of PLC in this organ. The concentration of PLC δ in bovine stomach of rumen, reticulum, omasum and abomasum that appeared in the first peak from HPLC-DEAE column was in the range of 10-14 ㎍ and those of PLC β and γ in second peak were 1-2 ㎍ and 5-18 ㎍ per 100 ㎎ soluble protein of bovine stomach homogenates respectively. This paper demonstrated that bovine stomach contain the type δ as the major form of PLC and relatively small amounts of PLC β and γ.

소의 뇌로부터 Calmodulin 단백질의 순수분리 및 생화학적 성질 연구

이상열,권헌영,김정희,이서구 ( Sang Yeol Lee,Heun Young Kwon,Jung Hye Kim,Sue Goo Rhee ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.2

Calmodulin, a heat stable Ca^(++)-binding protein, is a multifunctional modulator, mediating many of the Ca^(++) effects in cellular functions. This protein interacts reversibly with Ca^(++) to form a protein/ Ca^(++) complex, whose activity is regulated by cellular flux of Ca^(++). Calmodulin from bovine brain was purified to complete homogeneity by heat, acid treatment and hydrophobic interaction chromatography. The biochemical properties of the purified protein were examined under various criteria. It was estimated to have an apparent molecular weight of 21K and 15K in the absence or presence of Ca^(++) respectively, which would mean the great conformational changes were induced by the binding of Ca^(++) to calmodulin. The calmodulin had distinct ultraviolet absorption peaks at 259, 265, and 279 nm due to phenylalanine and tyrosine residues. Also, this protein activated the Ins(1,4,5) P₃-Kinase of which role is very important in cellular signal transduction, about seven folds (at 6 μM Ca^(++) and 1.0 μM calmodulin) with a Ca^(++)-dependent manner.

Spatial-Temporal Modelling of Road Traffic Data in Seoul City

이상열,안수한,박창이,전종우,Lee, Sang-Yeol,Ahn, Soo-Han,Park, Chang-Yi,Jeon, Jong-Woo The Korean Data and Information Science Society 2002 한국데이터정보과학회지 Vol.13 No.2

Recently, the demand of the Intelligent Transportation System(ITS) has been increased to a large extent, and a real-time traffic information service based on the internet system became very important. When ITS companies carry out real-time traffic services, they find some traffic data missing, and use the conventional method of reconstructing missing values by calculating average time trend. However, the method is found unsatisfactory, so that we develop a new method based the spatial and spatial-temporal models. A cross-validation technique shows that the spatial-temporal model outperforms the others.

기능성 상부 위장관 증상을 호소하는 환자의 스트레스, 불안 및 우울

이상열,신성훈,최석채,Lee, Sang-Yeol,Shean, Sung-Hun,Choi, Suk-Chei 한국정신신체의학회 1998 정신신체의학 Vol.6 No.1

Objective : The sensation of dysphagia, heartburn, globus hystericus, and functional dyspepsia are common symptoms of the functional upper gut disorders. This study was designed to investigate quantity of perceived stress, depression, and anxiety in the patients with functional upper gut symptoms whose esopahgeal manometry(EM) and gatroesophageal reflux (GERT) test were normal. Methods : A total of 38 patients who complained of the symptoms had been tested with 24-hour ambulatory EM and conventional GERT in our gastrointestinal clinic. Thirty patients whose tests had been normal(patients group) were assessed with Symptom Checklist-90-Revision(SCL-90-R), Beck Depression Inventory(BDI), and Spielberger Stait-Trait Anxiety Inventory(STAI) and compared with 30 patients(control group) without functional upper gut symtpoms in the hepatobiliary clinic. The two groups were also assessed by quantity of perceived stress during the last year through self-report. Results: 1) These patients tended to be predominently female, older, and possessed a lower education than control group. 79% of 38 patients who had been tested were normal. 2) Compared to the control group, the patients had significantly higher mean scores on four subscales(somatization, depression, anxiety, and positive symptom distress index). 3) The patient group had significantly more perceived stress than the control group. 4) The patients group had significantly higher levels of depression than the control gorup, but there was not any significant difference in the STAI. 5) There were significant positive correlations between the BDI score and the STAI-trait, the STAI-stait and the STAI-trait, the quantity of perceived stress and the STAI-trait. Conlusion : The patients with functional upper gut symptoms displayed more, psychological distress, sornatization, anxiety, and deperssion. Among them, patients had higer depression than control group. Functional upper gut symtoms could be more appropriately viewed as somatic symptoms of depression. These findings suggest that such patients need to have psychiatric intervention and treatment.

The Effects The Type of Canes-Handle Affects in Recovering-Balance of Hemiplegic patients

이상열,이명희,박민철,한진태,권오현,배성수,Lee, Sang-Yeol,Lee, Myoung-Hee,Park, Min-Chull,Han, Jin-Tae,Kweon, Oh-Hyun,Bae, Sung-Soo The Korean Society of Physical Therapy 2008 대한물리치료학회지 Vol.20 No.4

Purpose: We compared T-type and I-type canes on postural balance in 28 hemiplegic patients. Methods: Subjects were allocated randomly into two groups: a T-shape cane group (n=14) and an I-shape cane group (n=14). Before the test, subjects were trained by a physical therapist to walk with a cane for 6 weeks. The Main Outcome Measures were measured as maximal sway velocity, sway path, sway area, and partial weight bearing using a Balance Performance Monitor (BPM) and ambulation velocity using a 'Timed up and go test'. We also measured the maximal ambulation velocity. Results: The distribution of weight bearing on the affected side without the cane was 35% in the I-shape cane group and 36% in the T-shape cane group. After training, weight bearing on the affected side increased by 45% in the I-shape cane group and 40% in the T-shape cane group. With the cane held in the hand, weight bearing on the affected side in the T-shape cane group decreased by 3%. Conclusion: The I-shaped cane increased static standing balance, including hemiplegic side weight bearing. Therefore, I-shape canes can improve the balance of hemiplegic patients.

완전 복합신소재 풍력타워 개발

이상열,지효선,강영종,Lee, Sang-Yeol,Ji, Hyo-Seon,Kang, Young-Jong 한국복합신소재구조학회 2012 복합신소재학회논문집 Vol.3 No.2

뉴 트렌드의 선두두자

이상열,Lee, Sang-Yeol (사)한국포장협회 2006 包裝界 Vol.157 No.-

H2-M3의 세포 표면 발현이 NK 세포의 활성에 미치는 영향 분석

이상열,전태훈,Lee, Sang-Yeol,Chun, Tae-Hoon 대한약학회 2009 약학회지 Vol.53 No.3

H2-M3 (M3) is a unique antigen presenting molecule which provides N-formylated peptide to certain type of T cells. Previous observation indicated that NK cell activity is significantly diminished during listerial infection in $H2-M3^{-/-}$ mice. To explore the possibility that M3 expression directly effect on NK cell activity, we measured NK cell activity with or without stimulation of N-formylated peptide on antigen presenting cells. Results indicated that the expression of M3 is not directly influence on NK cell activity. Further study will be focused on the indirect effect of M3 on regulating NK cell activity.

초대 칼럼-고유가로 고통받고 있는 서민과 중산층을 위한 특단의 대책이 시급하다

이상열,Lee, Sang-Yeol 대한석유협회 2007 석유와 에너지 Vol.262 No.-