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고지방식이 수컷 micro-pig에서 경신강지환(經身降脂丸) (GGEx)의 고지혈증 개선효과
양유인,정양삼,이희영,이상달,김병출,김종훈,석화준,유재상,윤기현,조주흠,김훈,김경철,신순식,Yang, Yoo-In,Jung, Yang-Sam,Lee, Hee-Young,Rhee, Sang-Dal,Kim, Byoung-Chul,Kim, Jong-Hoon,Seok, Hoa-Jun,Yoo, Jae-Sang,Yoon, Ki-Hyeon,Jo, Ju-Heum,Kim, 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.2
Objectives : We evaluated anti-hyperlipidemia effect of Gyeongshinganjeehwan (GGEx) in high fat induced obese male micro-pigs. Methods : 7 month-old micro-pigs are fed with normal (n = 3) or high fat diet (n = 18) for 12 weeks. The pig revealed obesity in high fat diet were divided into 2 groups (n = 5 each) and vehicle (OMP) and Gyeongshingangjeehwan (GGEx, 616.7 mg/kg/day) were administrated for 1 month. We monitored the changes in body weight and measured plasma cholesterol, triglyceride, free fatty acid, GOT and, GPT after 1 month. The visceral fat were measured with computerized tomography and weights of various organs were measured after sacrifice. Results : 1. GGEx group had significantly reduced body weight gain than obese control group in statistics. 2. GGEx group didn't significantly differ from obese control group in blood total cholesterol, blood LDL-cholesterol, blood triglyceride. but it's data were similar to normal control group. 3. GGEx group had prominantly reduced visceral fat than obese control group in computerized tomography. 4. Blood GOT and GPT didn't differ from between groups. The organ weight were not significant different. And it is normal in size and colour of visceral organs. Conclusions : It is concluded that GGEx has anti-hyperlipidemia effect by improving visceral fat and access to security.
최명복,이상운,김봉경,정승삼,한태용,Choi, Myeong-Bok,Lee, Sang-Un,Kim, Bong-Gyung,Joung, Seung-Sam,Han, Tae-Yong 한국인터넷방송통신학회 2011 한국인터넷방송통신학회 논문지 Vol.11 No.6
본 논문은 $m$개의 후보 시설과 $n$개의 거주지역이 존재하는 경우, 비용 (주민수 ${\times}$ 최단거리) 측면에서 $p$개의 최적의 시설 위치를 선정하는 알고리즘을 제안하였다. 이 문제는 다항시간 알고리즘이 제안되지 않아 NP-난제로 분류되어 있다. 본 논문에서는 각 지역에서의 최소 비용을 선택한 $p=m$의 시설로부터 각 지역을 다음 최소 비용 시설로 이동시킬 경우 최소비용합으로 삭제할 수 있는 후보 시설을 $p=2$가 될 때까지 한 번에 하나씩 제거하는 방법으로 역-삭제 방법이다. 제안된 알고리즘은 다양한 문제들에 적용한 결과 $m{\times}n$이 $5{\times}5$, $7{\times}7$인 경우에는 초기 해로 최적해를 구하였다. Swain의 55-노드 망에 대해서는 $p=4$인 경우 해 개선 과정을 수행하여 최적해를 구하였으며, $p=5$인 경우에는 초기해로 최적해를 구하였다. This paper suggests $p$-facility locations in $m$ candidate locations and $n$ areas in optimal cost side(population${\times}$shortest distance). This problem has been classified by NP-complete because there is not a polynomial time algorithm. In this paper, we suggests reverse-delete method that deletes a candidate facility one by one from $p=m$ until $p=2$. As a result of the proposed algorithm for the $5{\times}5$ and $7{\times}7$, the initial solution is obtained. For the Swain's 55-node network, we obtain the optimal solution through a solution improvement process with $p=4$ and it by using the initial solution with $p=5$.
시호연(Hoyeon Shi),이상삼(Sang-Sam Lee),전형욱(Hyuong-Wook Chun),송환진(Hwan-Jin Song),노영찬(Young-Chan Noh),손병주(Byung-Ju Sohn) 한국기상학회 2016 대기 Vol.26 No.2
Optical properties of aerosols associated with haze events over Seoul were examined using ground-based skyradiometer and satellite-borne CALIOP and MODIS measurements over the 2009~2010 period. It is shown that aerosol optical thickness (AOT), Ångström exponents (α), and fine-mode particles increase during the haze events. The CALIOP-measured vertical profiles of aerosol during the haze events revealed that most of aerosols are loaded within layers below 4 km altitude. A large portion of these events appear to be related to the long-range transport of aerosols from China; about 35% and 18% of the haze events observed over Seoul were traced back to northern China and southern China, respectively. Compared with optical properties for locally-induced haze events (25%), these long-range transported aerosols are found to have relatively higher AOTs.
이효정(Hyo-Jung Lee),이은희(Eun-Hee Lee),이상삼(Sang-Sam Lee),김승범(Seungbum Kim) 한국기상학회 2012 대기 Vol.22 No.1
The PM10 concentration data isuseful for indentifying intensity and a transport way of Asian dust. However, it is difficult to identify them property due to the limited spatial resolution and coverage. Therefore, a methodology to estimate PM10 concentration using visibility data obtained from synoptic observation was developed. To derive the converting function, correlation between visibility and PM10 concentration is investigated using visiblity and PM10 concentration data observed at 20 stations in Korea from 2005 to 2009. To minimize bias due to atmospheric moisture, data with higher relative humidity over a critical value were eliminated while deriving PM10-visibility relationship. As a result, an exponentially decreasing function of visibility converting function to PM10 concentration was carried out for the dust cases in 2010. It was found that spatial distributions of PM10 calculated by visibility atr in good agreement between the derived PM10 distribution, especially for the strong dust cases in 2010. And correlation between the derived and observed PM10 concentration was 0.63. We applied the function to obtain distributions of PM10 concentration over North Korea, in which concentration data are not available, and compared them with satellite derived dust index, IODO distributions for dust cases in 2010. It is shown that the visibility function estimates quite similar patterns of dust concentration with IODI image, which suggests that it can contribute for prediction by indentifying transport route of Asian dust.
고해상도 규모상세화 수치자료 산출체계(KMAPP)를 이용한 저고도 항공난류 진단
석재혁,최희욱,김연희,이상삼,Seok, Jae-Hyeok,Choi, Hee-Wook,Kim, Yeon-Hee,Lee, Sang-Sam 한국항공운항학회 2020 한국항공운항학회지 Vol.28 No.4
In order to diagnose low-level turbulence in Korea, diagnostic indices of low-level turbulence were calculated from Aug 2016 to Jul 2019 using a Korea Meteorological Administration Post Precessing (KMAPP) developed by the National Institute Meteorological Sciences (NIMS), and the indices were evaluated using Aircaft Meteorological Data Relay (AMDAR). In the mean horizontal distribution of diagnostic indices calculated, severe turbulence was simulated along major domestic mountains, including near the Taebaek Mountains, the Sobaek Mountains and Hallasan Mountain on Jeju Island due to geographical factors. Later, detection performance was evaluated by calculating the KMAPP Low-Level Turbulencd index (KLT) on combined index, using AUC value of Individual diagnostic indices as a weight. The result showed that the AUC value of KLT was 0.73, and the detection performance was improved (0.02-0.13) when the index was combined. Also, when looking for the AMDAR data is divided into years, seasons, and altitudes, up to 0.94 AUC values were found in winter (DJF) and the surface (surface-1,000ft). By using high-resolution numerical data reflecting detailed terrain data, local turbulence distribution was well demonstrated and high detection performance was shown at low-level.
한태용(Han Tae-Yong),정승삼(Joung Seung-Sam),이상운(Lee Sang-Un) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.4
This paper suggests maximum capture sports facility p, (p = q) location of new finn FA in the market that has been operating q of finn FB. We apply as if the number of customer in any facility is less than threshold value T then the facility will be closed. Serra and ReVelle suggests heuristic concentration algorithm. But this algorithm performs many times and can’t be find the optimal solution. But, the proposed algorithm applies simple rule and can be obtains optimal solution. For the Swain’s 55-node network, Serra and ReVelle find the FA’S facility location with 75.7% market share. But proposed algorithm search the FA’S facility location with 79.1% market share.