유착성 관절낭염에서 관절강내 스테로이드 주사 치료의 최신 지견

오주헌,정인호,박은우,조장혁 계명대학교 의과대학 2022 계명의대학술지 Vol.41 No.2

Adhesive capsulitis of the shoulder joint is a common disorder characterized by a gradual increase of pain and limitation in range of motion of the shoulder joint. The pathophysiological process involves fibrous inflammation of the capsule leading to capsular thickening and contracture. Intra-articular corticosteroid injection is commonly performed in patients with adhesive capsulitis. However, there is no consensus as to the best injection site. Corticosteroid injection sites for the treatment include posterior capsule approach, rotator interval approach, multi-site, and subacromial injection. All injection methods lead to improvement in adhesive capsulitis cases. In this review article, we provide an overview of current corticosteroid injection methods for adhesive capsulitis.

비전 트랜스포머 기반 디지털 병리 대장암 진단 모델

오주헌(Ju Heon Oh),김경은(Kyung Eun Kim),송보람(Bo Ram Song),이주천(Ju Cheon Lee),이재웅(Jae Ung Lee),전예진(Ye Jin Jeon),Vuong Thi Le Trinh,Syed Farhan Abbas,곽진태(Jin Tae Kwak) 대한전자공학회 2022 대한전자공학회 학술대회 Vol.2022 No.6

하중-변위 관계를 고려한 물류 이동 Conveyor 의 Motor Roller Bracket 최적 설계

오주헌(J. H. Oh),오윤형(Y. H. Oh),임현욱(H. W. Lim) 한국정밀공학회 2013 한국정밀공학회 학술발표대회 논문집 Vol.2013 No.5월

이종 영상 데이터를 활용한 흉부 X-ray 코로나 바이러스 질병 탐지 모델

오주헌(Ju-Heon Oh),한창희(Chang-Hee Han),이주천(Ju-Cheon Lee),웅티레트린(Trinh Thi Le Vuong),곽진태(Jin-Tae Kwak) 한국정보과학회 2021 한국정보과학회 학술발표논문집 Vol.2021 No.12

Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas

김지인,오주헌,Heather Harlem,Michael D. Culler,구철룡,이은직 대한내분비학회 2020 Endocrinology and metabolism Vol.35 No.1

Background: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing efforts to develop new drugs withimproved effectiveness for this disease. BIM23B065 is a novel chimeric molecule that acts on both somatostatin and dopamine receptors. This study aimed to investigate the effects of BIM23B065 compared with those of a somatostatin receptor analog and a dopamine agonist. Methods: The effects of BIM23B065 on the proliferation, GH and insulin-like growth factor-1 (IGF-1) levels, and extracellular signal-regulated kinase (ERK) 1/2 and cyclic AMP response element binding (CREB) phosphorylation of GH3 cells were investigatedwith MTS assay, enzyme-linked immunosorbent assay, and Western blotting, respectively. The dosage and treatment duration ofBIM23B065 were tested in animal models of GH-secreting pituitary adenoma. The effect of BIM23B065 (3 mg/kg/day) on changesin IGF-1 levels before and after treatment was further investigated. Results: In vitro, BIM23B065 treatment decreased GH release in the culture media and downregulated ERK 1/2 and CREB phosphorylation to 22% and 26%, respectively. In vivo, IGF-1 expression decreased to 50 % after 4 weeks of treatment with BIM23B065using an osmotic pump implant. Moreover, magnetic resonance imaging results showed that the tumor size decreased significantlyfollowing treatment with BIM23B065 for 4 weeks. Conclusion: The novel chimeric molecule was effective in decreasing IGF-1 and GH levels and may serve as an effective therapeuticagent for acromegaly.

HFSS 기반 소형 패치안테나 설계

김지웅,오주헌,안병구 한국인터넷방송통신학회 2012 한국인터넷방송통신학회 논문지 Vol.12 No.3

현재 우리는 보이지 않지만 다양한 주파수대의 전파가 세상을 주도하는 시대에 살고 있다. 무선 모바일 통신의 시대로 빠르게 변화하고 있는 지금 안테나(특히, 소형 패치 안테나)의 중요성은 높아져 가고 있다. 본 논문에서는 핸드폰 같은 기기를 통해 DMB, GPS 기능을 가능하게 하는 소형 패치안테나를 제작한다. 설계 제작된 패치안테나의 주요한 특징 및 기여도는 다음과 같다. 첫째, 패치안테나는 HFSS를 이용하여 설계하고 세라믹 소재로 안테나를 제작하였다. 둘째, 네트워크 분석기와 챔버를 이용해 제작된 안테나의 성능테스트 단계를 거쳐 안테나를 소형화하고 수신이득을 높여 더 많은 소형기기에 접목시킬 수 있도록 하였다. Currently, we are living in the world of invisible radio waves with a variety of frequencies. As today's society is rapidly changing to an era of wireless communication, the importances of antenna(especially, small patch antenna) are increasing according to the coming of wireless mobile communication society. In this paper, we design a small patch antenna which can support the functions of DMB and GPS through devices like cellular phone. The main feature and contribution of the designed patch antenna are as follows. First, the patch antenna is designed by HFSS and the ceramic materials for the patch antenna is utilized. Second, we obtain the patch antenna with reduced size and increased profit of reception, and the designed patch antenna can be applied for small devices.

Diagnostic Patterns in the Evaluation of Patients Presenting with Syncope at the Emergency or Outpatient Department

강구현,김준수,오주헌,온영근,송형곤,조익준,김수진,배수진,신태건 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.3

Purpose: Patterns of syncope evaluation vary widely among physicians and hospitals. The aim of this study was to assess current diagnostic patterns and medical costs in the evaluation of patients presenting with syncope at the emergency department (ED) or the outpatient department (OPD) of a referral hospital. Materials and Methods: This study included 171 consecutive patients with syncope, who visited the ED or OPD between January 2009 and July 2009. Results: The ED group had fewer episodes of syncope [2 (1-2) vs. 2 (1-5), p=0.014] and fewer prodromal symptoms (81.5% vs. 93.3%, p=0.018) than the OPD group. Diagnostic tests were more frequently performed in the ED group than in the OPD group (6.2±1.7 vs. 5.3±2.0; p=0.012). In addition, tests with low diagnostic yields were more frequently used in the ED group than in the OPD group. The total cost of syncope evaluation per patient was higher in the ED group than in the OPD group [823000 (440000-1408000) won vs. 420000 (186000-766000) won, p<0.001]. Conclusion: There were some differences in the clinical characteristics of patients and diagnostic patterns in the evaluation of syncope between the ED and the OPD groups. Therefore, a selective diagnostic approach according to the presentation site is needed to improve diagnostic yields and to reduce the time and costs of evaluation of syncope. Purpose: Patterns of syncope evaluation vary widely among physicians and hospitals. The aim of this study was to assess current diagnostic patterns and medical costs in the evaluation of patients presenting with syncope at the emergency department (ED) or the outpatient department (OPD) of a referral hospital. Materials and Methods: This study included 171 consecutive patients with syncope, who visited the ED or OPD between January 2009 and July 2009. Results: The ED group had fewer episodes of syncope [2 (1-2) vs. 2 (1-5), p=0.014] and fewer prodromal symptoms (81.5% vs. 93.3%, p=0.018) than the OPD group. Diagnostic tests were more frequently performed in the ED group than in the OPD group (6.2±1.7 vs. 5.3±2.0; p=0.012). In addition, tests with low diagnostic yields were more frequently used in the ED group than in the OPD group. The total cost of syncope evaluation per patient was higher in the ED group than in the OPD group [823000 (440000-1408000) won vs. 420000 (186000-766000) won, p<0.001]. Conclusion: There were some differences in the clinical characteristics of patients and diagnostic patterns in the evaluation of syncope between the ED and the OPD groups. Therefore, a selective diagnostic approach according to the presentation site is needed to improve diagnostic yields and to reduce the time and costs of evaluation of syncope.

Next.js와 Express.js를 활용한 전기 자동차 대여 시스템

허태성(Hur Tai-sung),오주헌(Oh Ju Heon) 한국컴퓨터정보학회 2023 한국컴퓨터정보학회 학술발표논문집 Vol.31 No.2

GIS를 활용한 도심 공간기능분석과 유형화에 관한 연구

김흥관 ( Heung Kwan Kim ),신용은 ( Yong Eun Shin ),백태경 ( Tae Kyung Baek ),강기철 ( Gi Cheol Kang ),정희수 ( Hee Su Jeng ),오주헌 ( Ju Heon Oh ),여성준 ( Sung Jun Yeo ) 한국지리정보학회 2007 한국지리정보학회지 Vol.10 No.4

부산시의 도심(축)에 속하는 15개 동을 대상으로 2000년, 2005년 두 개 연도를 LQ지수와 군집분석을 통해 도심의 공간기능에 대하여 연구하였다. 2000년도의 LQ지수를 분석한 결과 2차산업은 재래시장과 대규모 상권이 형성된 지역에 특화되어 나타나고 있으며, 3차산업은 금융권이 집중되어 있는 지역에서 특화되어 나타나고 있다. 2005년도의 LQ지수는 2000년도의 LQ지수와 거의 변화가 없었으나, 3차산업에 속하는 도심의 중심업무기능이 구도심에서 급격히 쇠퇴하고 신도심으로 대변되는 서면지역에서 높게 나타나 특화되고 있었다. 이는 과거 구도심의 중심업무기능이 신도심으로 이동함에 따라, 구도심의 도심의 성격을 지닌 주요 기능이 쇠퇴하고 있음을 나타낸다. 그 다음으로 LQ지수를 이용하여 군집분석을 실시한 결과, 3개 군집으로 분류 할 수 있었다. 먼저 1군집은 도심 쇠퇴현상이 나타나는 구도심지역이고, 2군집은 주거기능이 강하게 나타나는 지역이며, 3군집은 현재, 도심의 공간기능이 매우 활발히 일어나고 있는 지역이다. 이에 본 연구에서는 다음과 같은 결과가 도출되었다. 첫째, 구도심의 쇠퇴를 억제할 수 있는 다양한 도심재생방안 수립과 신도심에 대한 종합적이고 체계적인 계획의 수립이 필요할 것이다. 둘째, 산업별 특화도에 따라서 도심 공간기능이 배치되므로 이에 지역에 적합한 산업의 도입과 함께 발전을 할 수 있는 기반의 조성이 필요할 것이다. The subjects were fifteen dong at downtown of Busan. LQ index and cluster analysis were used to research space functions of downtown in both years, that is to say, 2000 and 2005. At the analysis of LQ index in 2000, the secondary industries were specialized at traditional markets as well as large-scaled commercial districts, while the tertiary industries were done at financial business districts. LQ index in 2005 did not make change mostly comparing with the one in 2000: But, main businesses at downtown that belonged to the tertiary industries rapidly dwindled at old downtown to make appearance at Seomyeon of new downtown. Main businesses at old downtown in the past moved to new downtown to dwindle main functions at old downtown. The cluster analysis was done by using LQ index to classify into three clusters. The first cluster was old downtown that functions of downtown dwindle, and the second cluster was residence area, and the third cluster was the area where space function at downtown was very much active. The findings were as follow: Firstly, various kinds of urban regeneration plans should be made to control dwindling of old downtown and to establish comprehensive and systematic plans on new downtown. Secondly, downtown space functions could be placed depending upon specialization of each industry so that industries being suitable to the area should be introduced to construct development base.