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택사 열수 및 에탄올 추출물의 항산화활성과 human LDL 산화억제 및 ACE 저해효과에 미치는 영향
양영이,이민자,정현정,이혜숙,김혁,나선택,박선동,박원환,Yang, Young-Yi,Lee, Min-Ja,Jung, Hyun-Jung,Lee, Hye-Sook,Kim, Hyuck,Na, Sun-Taek,Park, Sun-Dong,Park, Won-Hwan 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.4
Objectives : The study was conducted to evaluate antioxidative, anti-atherosclerotic and anti-hypertensive effects of natural remedies. Alisma Rhizome (AR) has been used for a long time in Asia in folk remedies for treatment of hypertension and stroke and has been used in Korean traditional medicine for the treatment of glycosuria, gonorrhea, hypercholesterolemia, hypertension, and jaundice and its diuretic effect. These pharmacological effects of AR might come from antioxidant properties of phytochemicals in these materials. Methods : In this study, the antioxidant activity of extract from AR was studied with in vitro methods by measuring the antioxidant activity by TEAC, measuring the scavenging effects on reactive oxygen species (ROS) [superoxide anion, hydroxyl radical] and on reactive nitrogen species (RNS) [nitric oxide and peroxynitrite] as well as measuring the inhibitory effect on $Cu^{2+}$ induced human LDL oxidation and on ACE. Results : The AR extracts were found to have a potent scavenging activity, as well as an inhibitory effect on LDL oxidation and on ACE against all of the reactive species tested, with the water extract showing particularly strong antioxidant activities. Conculsions : The AR extracts have antioxidative, anti-atherosclerotic and anti-hypertensive effects in an in vitro system, which can be used for developing pharmaceutical drugs against oxidative stress and atherosclerosis.
ISE:Behavior 합성 환경 구현을 위한 시스템 개발
양영일 대한전자공학회 1996 CAD 및 VLSI 설계연구회지 Vol.5 No.1
In this paper, we developed the Interactive Synthesis Environment (ISE) which supports designs from behavioral level on down to the floorplan level. This paper emphasizes interactivity by illustrating the use of the different design views and quality metrics in the typical design scenario. The ISE provides highly integrated views and an environment that allows the user to work in any abstraction of the design and yet be able to relate objects in different abstractions. Finally, the ISE offers numerous quality metrics and hints that assists the user in making complex design decisions. Using the ISE, a designer can explore the design space quickly, and expect to reduce design time by 50io, and the number of iterations in the design cycle to only few.