문화 체험 프로그램 중심의 한국어 교재 개발 방안-국내 외국인 한국어 학습자를 중심으로-

안기정,권순희 국제한국어교육학회 2020 한국어 교육 Vol.31 No.4

The purpose of this study is to suggest a new direction of Korean cultural education according to the changes of the times, the educational environment, and the needs of learners. The societal change caused by COVID-19 has led some to suggest online culture classes; however, learners continue to request cultural experiences. Considering that cultural experiences remain necessary, our goal is to create a cultural experience program that can be used in the future of Korean language education while keeping COVID-19 in mind. In this paper, we recognize that Korean language education currently relies mainly on knowledge transfer and that cultural education and language education are being handled separately. Therefore, we propose a cultural education which encourages active participation of the learners. Accordingly, we must first move away from a paper-based study of culture and instead create cultural lessons that focus on actual experiences in order to allow learners to cultivate their ability to learn about and adapt to Korean culture. In order to accomplish this, we created a textbook that allows learners to selectively progress through grammar, speaking, listening, writing, and reading activities. The experiential education plan for Korean culture presented in this paper will increase the learners’ motivation through learner-centered education while facilitating a deeper understanding of Korean culture.

부재료 배합비와 숙성기간을 달리한 오이지의 물리적 및 이화학적 특성

안기정,심영현 서울여자대학교 자연과학연구소 1997 자연과학연구논문집 Vol.9 No.-

The changes of pH, acidity, changes in color, turbidity and hardness in maximum cutting force of the Backdooung and Sancho added Korean pickled cucumbers fermented at 25℃ were investigated. Korean pickled cucumbers frequently soften during fermentation and brine storage. Traditionally, old cookery 'Soowunjapbang' added the Backdooung and Sancho. So, the purpose of the study are determine the Backdooung and Sancho added amount. Results ot study showed the Backdooung and Sancho(10g : 10g) added to 10% salt brine increased the hardeness of Korean pickled cucumbers and inhibited softening. When fermentation pH, acidity of early period was increased and lately period was decreased. The changes in color, the Backdooung and Sancho added Korean pickled cucumbers showed significantly. Turbidity of prepared solution by different minor ingredient was significantly. The data confirmed that the wavelength of H-treated group was very high. According to the fermentation period in changes of color, 30 days was high at 420, 440, 666nm

흑마늘 가루 첨가 설기떡의 품질 특성 및 항산화 활성

안기정 (사)한국조리학회 2021 한국조리학회지 Vol.27 No.7

The proper ratio and quality characteristics of black garlic powder Sulgidduk were investigated. The physical properties of Sulgidduk, such as moisture content, color, texture DPPH radical scavenging activity, total polyphenol content, and Sensory characteristics preference such as color, flavor, texture, softness, and overall acceptability, were measured as follows. The moisture content decreased significantly as the level of black garlic powder added increased, and the Hunter's values showed a tendency of decreasing L and b values and increasing a value as the added level of black garlic powder increased. As a result of texture characteristics of black garlic powder Sulgidduk, the hardness decreased significantly as the added level increased. It was found that springiness, cohesiveness, and chewiness were also significantly reduced in all items. The level of total polyphenol contents was larger in the amount of black garlic powder added increased. The DPPH radical scavenging activity increased significantly as the amount of black garlic powder added increased, and the sensory characteristics preference results for color and softness increased significantly as the amount added increased. In this study, we intend to present basic data along with the optimal mixing ratio in order to maximize the use of black garlic powder containing antioxidants to utilize domestic agricultural products and to manufacture functional rice cakes with excellent sensory qualities.

Lymphovascular invasion as a negative prognostic factor for triple-negative breast cancer after surgery

안기정,박지선,최윤선 대한방사선종양학회 2017 Radiation Oncology Journal Vol.35 No.4

Purpose: This study aimed to evaluate the prognostic effects of lymphovascular invasion (LVI) in triple-negative breast cancer (TNBC) patients who underwent surgical resection. Materials and Methods: A total of 63 non-metastatic TNBC patients who underwent surgical resection were retrospectively investigated from 2007 to 2016 in Inje University Busan Paik Hospital. Pathological tests revealed that 12 patients (19.0%) had LVI. Approximately 61.9% (n = 39) of the patients’ samples stained positive for p53. Additional chemotherapy and radiotherapy (RT) were performed in 53 (84.1%) and 47 (74.6%) patients, respectively. Results: The median follow-up period was 39.5 months (range, 5.9 to 123.0 months). The pathological T stage (p = 0.008), N stage (p = 0.014), and p53 positivity (p = 0.044) were associated with LVI. Overall, the 3-year disease-free survival (DFS) rate and overall survival (OS) rate were 85.4% and 90.2%, respectively. Ten patients (15.9%) experienced relapse. LVI (n = 12) was associated with relapses (p = 0.016). p53 positivity was correlated with poor DFS (p = 0.048). Furthermore, LVI was related to poor DFS (p = 0.011) and OS (p = 0.001) and considered as an independent prognostic factor for DFS (p = 0.039). The 3-year DFS of patients with LVI (n = 12) was only 58.3%. Adjuvant RT minimized the negative prognostic effect of LVI on DFS (p = 0.068 [with RT] vs. p = 0.011 [without RT]). Conclusion: LVI was related to the detrimental effects of disease progression and survival of TNBC patients. Thus, a more effective treatment strategy is needed for TNBC patients with LVI.

Checklist of the Staphylinidae (Coleoptera) in Korea

안기정,조영복,김윤호,유인성,Alfred F. Newton 국립중앙과학관 2017 Journal of Asia-Pacific Biodiversity Vol.10 No.3

A list of the 646 described species of Staphylinidae in Korea is presented. The list is in taxonomicsequence by subfamily, tribe, and genus and includes 215 genera in 55 tribes and 18 subfamilies. Weprovide the page reference of the original description of every species and genus listed, of many synonyms,and of all the Korean records. The list provides distribution of all the species by country (and forthe larger countries, by province or state). A brief taxonomic history of the Korean Staphylinidae ispresented. A complete bibliography is provided.

택시운송사업의 발전에 관한 법률

안기정,An, Gi-Jeong 대한교통학회 2014 교통 기술과 정책 Vol.11 No.3

서울-인천 간 물류·유통의 효율화 어떻게 할 것인가?

안기정,신성일 서울연구원 2010 정책리포트 Vol.- No.62

서울시 택시서비스 향상 방안

안기정 서울연구원 2011 정책리포트 Vol.- No.97

Enhancement of radiation effect using beta-lapachone and underlying mechanism

안기정,이형식,배세경,송창원 대한방사선종양학회 2013 Radiation Oncology Journal Vol.31 No.2

Beta-lapachone (β-Lap; 3,4-dihydro-2, 2-dimethyl-2H-naphthol[1, 2-b]pyran-5,6-dione) is a novel anti-cancer drug under phase I/II clinical trials. β-Lap has been demonstrated to cause apoptotic and necrotic death in a variety of human cancer cells in vitro and in vivo. The mechanisms underlying the β-Lap toxicity against cancer cells has been controversial. The most recent view is that β-Lap, which is a quinone compound, undergoes two-electron reduction to hydroquinone form utilizing NAD(P)H or NADH as electron source. This two-electron reduction of β-Lap is mediated by NAD(P)H:quinone oxidoreductase (NQO1), which is known to mediate the reduction of many quinone compounds. The hydroquinone forms of β-Lap then spontaneously oxidizes back to the original oxidized β-Lap, creating futile cycling between the oxidized and reduced forms of β-Lap. It is proposed that the futile recycling between oxidized and reduced forms of β-Lap leads to two distinct cell death pathways. First one is that the two-electron reduced β-Lap is converted first to one-electron reduced β-Lap, i.e., semiquinone β-Lap (SQ)ㆍ- causing production of reactive oxygen species (ROS), which then causes apoptotic cell death. The second mechanism is that severe depletion of NAD(P)H and NADH as a result of futile cycling between the quinone and hydroquinone forms of β-Lap causes severe disturbance in cellular metabolism leading to apoptosis and necrosis. The relative importance of the aforementioned two mechanisms, i.e., generation of ROS or depletion of NAD(P)H/NADH, may vary depending on cell type and environment. Importantly, the NQO1 level in cancer cells has been found to be higher than that in normal cells indicating that β-Lap may be preferentially toxic to cancer cells relative to non-cancer cells. The cellular level of NQO1 has been found to be significantly increased by divergent physical and chemical stresses including ionizing radiation. Recent reports clearly demonstrated that β-Lap and ionizing radiation kill cancer cells in a synergistic manner. Indications are that irradiation of cancer cells causes long-lasting elevation of NQO1, thereby sensitizing the cells to β-Lap. In addition, β-Lap has been shown to inhibit the repair of sublethal radiation damage. Treating experimental tumors growing in the legs of mice with irradiation and intraperitoneal injection of β-Lap suppressed the growth of the tumors in a manner more than additive. Collectively, β-Lap is a potentially useful anti-cancer drug, particularly in combination with radiotherapy.

DELTA: 반날개(Coleoptera: Staphylinidae)의 분류형질 데이터베이스

안기정,조영복 한국통합생물학회 1998 한국동물학회 뉴스레터 Vol.15 No.2