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      • 흰쥐 하수체 적출이 그 장간막 비만세포에 미치는 영향

        배선한,이갑재 中央醫學社 1972 中央醫學 Vol.22 No.4

        Mature male Swiss albino rats, weighing about 200gm each, were divided into groups of normal, hypophysectomy, and sham operation, and the hypophysectomized group was further divided into five subgroups of 1-, 2-, 3-, 5-, and 7-postoperative days. The authors then observed the number as well as the structure of the mast cells in the mesentery with the following results: 1. In the normal group, the number of mast cells appearing in the mesentery was on an average 32.73 per view field of 160X, about 7. 3 percent of which were degranulated cells. 2. In the group of sham operation, the average number of mast cells and the ratio of that of degranulated cells was similar to the value in the case of the normal group. 3. In general, in the group of hypophysectomy no marked change was observed in the number of mast cells, and only the 7-day subgroup showed a significant decrease(17%). The marked change was increase in the number of degranulated cells and this number increased with the lapse of time, finally reaching, in the 7-day subgroup, the level twice as large as that of the normal group. In addition, the shape of a cell took a somewhat irregular form with the passing of time. Furthermore, the size of granules in the cytoplasm became uneven, and the stain ability turned from metachromatic to orthochromatic, showing weak staining in general. Vacuolation was observed to increase. 4. To sum up the above, it can be concluded that the mast cells in the mesentery are not affected in number by hypophysectomy, but undergo notable structural changes due to this operation.

      • 광안리 해수욕장의 최소 해빈폭 관리를 위한 양빈 설계

        배선한,이정렬 한국재난정보학회 2015 한국재난정보학회 학술대회 Vol.2015 No.11

        본 연구는 해변의 양측에서 퇴적되고 해변 중앙에서 침식이 일어나고 있는 광안리 해수욕장에 최소 해빈폭을 최대로 하는 최적의 양빈 설계를 하고자 실시하였다. 광안리 해수욕장에 3가지 case의 양빈안을 수치 모의 시나리오로 구성하여 OneLine Shoreline Model 을 적용하여 해빈폭의 시간적 변화를 모의하였으며, Cross-shore Profile Model을 적용하여 연평균 파고 에 따른 전진폭과 최고 파고에 따른 침식폭을 추정하였다.

      • KCI우수등재
      • KCI등재

        천국천사들의 수학

        배선복(Bae Sun Bok) 철학연구회 2013 哲學硏究 Vol.0 No.103

        St. Anselm treats in his work Cur Deus Homo, Book 1, Ch.16-18 the possibility of fulfillment of membership of heavenly kingdom through an equal proportional division of fallen angels andfaithful human beings. Anselm argues for the constitution of heavenly membership, but he envisions that the membership of heavenly kingdom as the perfect number is a zero sum game. The perfect number goes neither minus nor plus in its left or right equation, but its membership comes up as long as comes down. (Angels/Humans)are such arithmetical formulas, in which St. Anselm arrives to conclusion, “Φ ∧ Ψ¬) ∨ (¬Φ ∧ Ψ)) ⊇ Ψ*”, where Φ belongs to member of angels, Ψ to human beings, but to Ψ* is required to add extra human beings as arrogant peoples or another angels. This conclusion can be semantical interpreted that rational beings are more than angels in the heavenly kingdom.According to methodological approach by D. P. Henry, D.Walton, S. L. Ukelmann, P. King, etc., who discovered agent logic in Anselm, I try to show a positive argument for the arrogant peoples and another angels who want to enter into the kingdom of heaven. Given two alternative attitudes for agents that they can choose facere esse or facere non esse, we can get q* in Ψ*, when they do truth making p ∧ ¬p or don`t truth making p ∧ ¬p. It means that another angels can get chance to enter into the kingdom of heaven.

      • KCI등재후보

        공업계 고등학교 전자과 '횡단보도제어기' 수업에서 함께 배우기 협동학습이 학업성취도에 미치는 효과

        배선,이상봉,금영충 한국기술교육학회 2006 한국기술교육학회지 Vol.6 No.1

        The purpose of this study was to verify the effects of Learning Together; one of cooperative learning techniques, on students' achievement of design activity of traffic lights controller at electronics education in industrial high school.The following null hypothesis was stated for the purpose of the study: There is no significant differences of achievement level between students who learned by ‘Learning Together’ cooperative learning and students who learned by traditional instructional method for design activity of traffic lights controller at electronics education in industrial high school according to (1) gender, (2) the level of entering behavior, (3) intelligence, and (4) personality.Posttest-Only Control Group design was applied for this experimental research. The data were collected and interpreted statistically by t-test using SPSS(ver. 10) at the .05 level of significance.The results of the study were as follow:(1) Learning together cooperative learning for design activity of traffic lights controller was effective on the 11th graders' achievement at electronic education in industrial high school.(2) The learning together for the design activity was effective on female students, while wasn't effective on male students.(3) The learning together for the design activity was effective on learning achievements of lower and middle group of students, while wasn't effective on higher group.(4) The learning together for the design activity was effective on lower intelligence group of students, while wasn't effective on middle and higher group.(5) The learning together for the design activity was effective on lower interpersonal relationship group and middle level of propensity to achieve group.

      • KCI등재

        Radiation Treatment in Pathologic N0-N1 Patients Treated with Neoadjuvant Chemotherapy Followed by Surgery for Locally Advanced Breast Cancer

        배선,박원,허승재,최두호,남석진,임영혁,안진석 한국유방암학회 2012 Journal of breast cancer Vol.15 No.3

        Purpose: This study evaluated the treatment results and the necessity to irradiate the supraclavicular lymph node (SCN) region in pathological N0-N1 (pN0-N1) patients with locally advanced breast cancer treated with neoadjuvant chemotherapy (NAC) followed by surgery and radiotherapy (RT). Methods: Between 1996 and 2008, 184 patients with initial tumor size >5cm or clinically positive lymph nodes were treated with NAC followed by surgery and RT. Among these patients, we retrospectively reviewed 98 patients with pN0-N1. Mastectomy was performed in 55%. The pathological lymph node stage was N0 in 49% and N1 in 51%. All patients received adjuvant RT to chest wall or breast and 56 patients (57%) also received RT to the SCN region (SCNRT). Results: At 5 years, locoregional recurrence (LRR)-free survival, distant metastasis-free survival, disease-free survival (DFS), and overall survival rates were 93%, 83%, 81%, and 91%, respectively. In pN0 patients, LRR was 7% in SCNRT−group and 5% in SCNRT+ group. In pN1 patients, LRR was 7% in SCNRT- group and 6% in SCNRT+ group. There was no significant difference of LRR, regardless of SCNRT. However, in pN1patients, there were more patients with poor prognostic factors in the SCNRT+ group compared to SCNRT- group. These factors might be associated with worse DFS in the SCNRT+ group, even though RT was administered to the SCN region. Conclusion: Our study showed the similar LRR, regardless of SCNRT in pN0-pN1 breast cancer patients after NAC followed by surgery. Prospective randomized trial is called for to validate the role of SCNRT.

      • KCI등재

        수술 후 보조적 방사선 치료를 포함한 근치적 치료를 받은 유방암 환자들의 뇌전이 발생률과 연관된 인자 분석

        배선,최두호,허승재,임도훈,박원,남희림,양정현,남석진,이정언,임영혁,안진석,박연희 한국유방암학회 2011 Journal of breast cancer Vol.14 No.-

        Purpose: To assess the incidence of brain metastasis in patients with breast cancer receiving surgery and adjuvant radiotherapy (RT) and to evaluate subtypes associated with brain metastasis. Methods: We retrospectively reviewed the medical records of 1,000 patients with breast cancer who were treated with surgery and adjuvant RT for a cure between January 2001 and July 2005 at Samsung Medical Center. Seventy-one patients received neoadjuvant chemotherapy before surgery. The pathological stage was I in 430 patients, II in 327, and III in 243. We divided the patients into three subtypes according to immunohistochemistry: triple negative (TN, 245 patients), human epidermal growth factor 2 (HER2) enriched (HE, 166 patients) and positive estrogen receptor or progesterone receptor without HER2 overexpression (EP, 589 patients). The median follow up time was 72 months after surgery. Results: Locoregional failure-free survival rate and distant metastasis-free survival rate at 5 years were 92.8% and 86.1%, respectively. The disease free survival rate and overall survival rate at 5 years were 84.6% and 94.7%, respectively. Thirty-nine patients had brain metastasis, and the brain metastasis-free survival rate at 5 years was 97.2%. A univariate analysis showed that younger age, neoadjuvant chemotherapy, modified radical mastectomy, advanced pathological stage and the TN and HE subtypes were significant risk factors for brain metastasis. A multivariate analysis revealed that age, neoadjuvant chemotherapy, pathological stage and the TN and HE subtypes were statistically significant factors for brain metastasis. Conclusion: The cumulative incidence of brain metastasis was 3.9% after curative treatment. If patients have a clinically suspicious symptoms suggesting brain metastasis, clinicians should be aware that an early brain imaging work up and management are necessary. Because patients with the TN or HE subtypes accompanied by younger age and advanced pathological stage have increased brain metastasis (>10%), annual regular imaging follow-up may be recommended for these high risk patients.

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