재발성 음경지속발기증 1례

박성환,백선호,한수련,안영민,안세영,이병철,Park, Sung-Hwan,Paik, Sun-Ho,Han, Su-Ryun,Ahn, Young-Min,Ahn, Se-Young,Lee, Byung-Cheol 대한한방내과학회 2011 大韓韓方內科學會誌 Vol.32 No.1

Priapism is a persistent penile erection that continues for more than 4 hours beyond, or is unrelated to, sexual stimulation. Because priapism is a medical emergency, all patients with priapism should be evaluated and treated urgently. Subtypes of priapism are ischemic, non-ischemic and stuttering priapism. Stuttering type is a recurrent form of ischemic priapism in which unwanted painful erections occur repeatedly with intervening periods of detumescence. The etiology of this type is often idiopathic and the treatments are still not clearly established. We present one case of stuttering priapism which occurred after suppression of his sexual desire. A 23-year-old man visited our clinic complaining of recurrent pain and erections persisting for about 5 weeks. We performed evaluation and confirmed the diagnosis of Rigid swollen penis. Jibaekjihwang-tang gamibang (ZhiBaiDihuang-Tang Jiaweifang) was administerd to the patient for 9 days. After the treatment, duration of erections and pain showed remarkable improvements. This will be recorded as the first case report of treating priapism with a Korean medical approach and suggests that Korean medicine therapy can be efficient to treat priapism.

전침 및 봉약침치료를 시술한 양성전립선비대증 환자의 임상증상개선에 대한 후향적 단면연구

박성환,한수련,강지석,안영민,안세영,이혜정,이병철,Park, Sung-Hwan,Han, Su-Ryun,Kang, Ji-Suck,Ahn, Young-Min,Ahn, Se-Young,Lee, Hye-Jung,Lee, Byung-Cheol 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3

Obejectives : To investigate the clinical effect of electroacupuncture and bee venom acupuncture for benign prostatic hyperplasia(BPH) symptoms. Methods : Among 39 outpatients who were treated at a BPH clinic, 8 were finally selected for analysis by charts-review, retrospectively. They were treated by electroacupuncture and bee venom acupuncture more than 3 times. We estimated the effectiveness of the treatments by using the International Prostate Symptom Score (IPSS) questionnaire and checking their nocturia frequency. On the basis of these variables, we analyzed the statistical significations of symptom improvements. Results : Among 8 patients, the IPSS and nocturia frequency showed significant improvement after the final treatment compared with baseline (P = .0078, P = .0078). The IPSS significantly decreased even after the 1st treatment and also after the 2nd treatment compared with the baseline (P = .0078, P = .0078). The IPSS at post final-treatment, post 1st- and post 2nd treatment also showed significant improvement compared with IPSS at baseline in 6 severe symptomatic patients(P = .031, P = .031, P = .031). Nocturia frequency decreased after the 1st treatment compared with baseline and showed significant improvement between baseline and post 2nd treatment (P = .0078). Conclusions : In a retrospective and cross-sectional study investigating the clinical effects of electroacupuncture and bee venom acupuncture on BPH, these treatments proved to have significant therapeutic effects, particularly for various symptoms involving frequent nocturia.

태조의 (太祖) 석각천문도와 (石刻天文圖) 숙종의 (肅宗) 석해천문도와의 비교

박성환 (Sung Hwan Park) 연세대학교 국학연구원 1987 동방학지 Vol.54-56 No.-

N/A

제주 Water 농축에 따른 3종 새싹채소의 생장 및 Vanadium의 흡수 특성

박성환(Sung-Hwan Park),윤지현(Ji-Hyun Yun),이진하(Jin-Ha Lee),이옥환(Ok-Hwan Lee),조주현(Ju-Hyun Cho) 한국식품영양과학회 2017 한국식품영양과학회지 Vol.46 No.7

제주 water를 농축하여 새싹유채, 메밀, 보리의 종자발아영향과 생장 및 vanadium 흡수특성을 알아보고자 실험을 수행하였다. 제주 water를 배수별로 농축시킨 결과 vanadium 농도가 제주 water 원수, 10배, 20배, 40배 농축수에서 각각 0.05 ㎎/L, 0.46 ㎎/L, 0.80 ㎎/L, 1.34 ㎎/L의 함량을 보였다. Control(수도수)과 제주 water 원수, 10배, 20배, 40배 농축수를 사용하여 종자발아율 측정 시 새싹유채의 경우 control과 제주 water 원수, 10배 농축수까지 발아율은 차이를 보이지 않았으나 농축배수가 20배, 40배로 증가할수록 발아율이 감소하는 경향을 보였으며, 특히 40배 농축수에서 발아율이 control과 비교하여 약 50% 감소하였다. 새싹메밀의 경우 농축배수가 증가할수록 종자 발아율이 control 42.7%에서 40배 농축수 60.7%로 발아율이 증가하는 것이 확인되었다. 새싹보리의 경우 control의 발아율 88.8%와 40배 농축수로 처리한 발아율 79.0%를 비교 시소폭 감소한 결과를 보이며, 20배 농축수까지 큰 영향은 없는 것으로 확인되었다. 새싹채소 생장 영향을 알아보고자 control(수도수), 제주 water 원수(0.05 ㎎/L), 제주 water 10배 농축수(0.46 ㎎/L)로 7일간 재배하여 확인한 결과 새싹유채의 경우 vanadium 농도가 높아질수록 지상부 길이, 뿌리의 생장이 모두 억제되었으며, 생물 중량 및 건조물 중량 또한 control과 비교 시 10배 농축수로 재배한 조건에서 감소하였다. 새싹메밀의 경우 vanadium 농도가 증가함에 따라 지상부 길이의 생장이 증가하였지만, 지하부 뿌리의 생장은 역으로 생장이 억제되었고, 생물 중량 및 건조물 중량 또한 새싹유채와 동일하게 vanadium 농도가 증가할수록 감소하였다. 새싹보리의 경우 새싹메밀과 동일한 경향으로 제주 water 원수 처리 시 control과 비교하여 지상부 생장이 억제되었지만 10배 농축수 처리 시 지상부의 생장이 증가하였고 뿌리생장은 억제되었으며, 생물 중량 및 건조물 중량은 control 대비 10배 농축수에서 감소하였다. 또한, 새싹채소의 vanadium 흡수특성을 확인한 결과 공통적으로 새싹유채, 새싹메밀, 새싹보리 control에서 vanadium 함량은 검출한계 이하의 함량을 보였다. 새싹유채의 경우 제주 water 원수와 제주 water 10배 농축수에서 각각 1.4 ㎎/㎏과 4.2 ㎎/㎏으로 함량이 3배 정도 차이를 보이는 것을 확인할 수 있었고, 새싹메밀의 경우 제주 water 원수와 10배 농축수로 재배한 경우 vanadium의 함량이 각각 1.3 ㎎/㎏, 2.9 ㎎/㎏으로 새싹유채보다 낮은 함량을 갖는 것으로 확인되었다. 새싹보리의 경우 vanadium 함량은 본 연구에서 제주 water 원수, 10배 농축수 재배조건 모두 검출한계 이하의 함량을 보였다. Vanadium is a trace mineral present in dietary sources, most commonly vegetables. The aim of this study was to investigate the growth and vanadium absorption characteristics of Brassica napus L., Fagopyrum esculentum, and Hordeum vulgare L. using different Jeju water concentrations. The growth of three sprout vegetables and absorption characteristics of vanadium were different depending on Jeju water concentration containing vanadium. In the case of B. napus L. and H. vulgare L., germination rate was inhibited by increasing Jeju water concentration, whereas in F. esculentum, the best germination rate (60.7 %) was obtained at 40 times concentration of Jeju water (vanadium, 1.34 ㎎/L). For the sprout growth, growth of shoots increased with increasing Jeju water concentration, but root growth was gradually inhibited by increasing Jeju water concentration. For the absorption of vanadium by Jeju water concentration, vanadium was not detected in H. vulgare L. The vanadium contents of B. napus L. and F. esculentum were 4.2 ㎎/㎏ and 2.9 ㎎/㎏ at 10 times concentration of Jeju water (vanadium, 0.46 ㎎/L), respectively.

전신성 홍반성 낭창환자에서 IMMUNOBLOT 법에 의한 항ENA 항체조사 -이중면역 확산법과 IMMUNOBLOT법의 비교-

박성환 ( Sung Hwan Park ),이상헌 ( Sang Heon Lee ),조철수 ( Chul Soo Cho ),김호연 ( Ho Youn Kim ) 대한류마티스학회 1995 대한류마티스학회지 Vol.2 No.1

Objective: Systemic Lupus Erythematosus (SLE) is characterized by various· autoantibodies to a variety of nuclear antigens. Certain extractable nuclear antigens (ENA) have been served as extremly useful aids in differentiation of clinical subset, diagnostic marker and in the detection of early forms of systemic rheumatic diseases. This study was to employ immunoblot to determine the prevalences of antibodies to ENA in SLE compared with immunodiffusion. Methods: Sera were obtained from 127 SLE patients. Antibodies to ENA were assessed by double immunodiffusion (DID) and immunoblot method. Results: Using the immunblot method, the prevalences of antibodies to ENA were as follows: The antibody to Sm was 27%, UIRNP 33.6%, Ro 41.8%, La 14%, ribosomal P 14% and Ku 4%. The prevalences of antibodies to ENA by DID were as follows: The antibody to Sm was 15%, RNP 24.5%, Ro 54.3% and La 9.4%. Conclusions: Compared with immunodiffusion, results using immunoblot showed greater sensitivity in the detection of autoantibodies to ENA in SLE.

셰익스피어와 버나드 쇼의 비교연구

박성환(Park Sung-Hwan) 새한영어영문학회 2000 새한영어영문학 Vol. No.

Bernard Shaw subtitled his Heartbreak House "A Fantasia in the Russian Manner on English Themes." The Russian Manner is Chekhovian: The English Themes are Shakespearean manner upon Shavian themes and images. Shakespeare's King Lear reverberates through Shaw's Heartbreak House. Shaw had hinted at the King Lear connection as soon as he had completed the play. Shaw had long continued "love-hate" relationship with Shakespeare because he felt that the Bard's shadow had darkened English theatrical landscape. Besides, Shaw was an iconoclast and destroyer of conventions. This paper is a comparative study over Shakespeare and Bernard Shaw through some literary resemblances and differences, parallels and reverses between Shakespeare's King Lear and Bernard Shaw's Heartbreak House. To do this Geoffrey Hartman's theory of relationship of the genius(present poet) with Genius(past masters) and genius loci(spirit of a particular age) are employed. According to Hartman, to create a truly iconoclastic art, a structure-breaking literature, to change the function of form from reconciliation and conservation to rebellion, and to participate in the enormity of present experience-these are the writer's Promethean endeavors. A great artist has the ambition to identify the Genius(past masters) of art with his own genius or that of a particular age(genius loci). If he admires the ancients, he trembles to rival them, but if he does not admire, he trembles before a void he must fill. Thus the artist's struggle with past masters and the pastness of art in modem society seems to be a version of a universal human struggle: of genius with Genius, and genius with genius loci. Here I have investigated the relationship of genius Shaw with Genius Shakespeare and genius loci through parallels and reversions as well as equivalents of some images, leit-motifs and themes in the two plays. The conclusion is that Shaw's Heartbreak House is a modem version of Shakespeare's King Lear, the latter reverberating through the former. For a total understanding of the two plays it will give the reader and audience a model of a better and more comprehensive understanding of dramatic literature as a whole enhancing their literary sentiments.

좁은잎천선과 잎 추출물 유래 항산화 활성 성분의 동정 및 효능 확인

박성환 ( Sung Hwan Park ),김정은 ( Jung Eun Kim ),염현숙 ( Hyun Sook Yeum ),이남호 ( Nam Ho Lee ) 대한화장품학회 2016 대한화장품학회지 Vol.42 No.4

본 연구에서는 좁은잎천선과 잎 추출물 및 극성별 용매 분획물의 항산화 활성을 검색하고 유효성분을 분리하여 화학구조를 규명하였다. 좁은잎천선과 잎 추출물 및 용매 분획물의 DPPH 및 ABTS⁺ 라디칼 소거 활성을 측정한 결과 에틸아세테이트 분획물에서 우수한 라디칼 소거 활성을 확인하였다. 활성이 좋은 에틸아세테이트 분획물에서 유효성분을 찾고자 vacuum liquid chromatography (VLC), silica gel column chromatography를 실시하였으며, 분리된 화합물은 ¹H 및 ¹³C NMR 데이터 분석 및 문헌치 비교를 통하여 총 5개의 화합물을 동정하였다. 분리된 화합물은 monoolein (1), oleic acid (2), lutein (3), afzelechin (4), catechin (5)으로 확인되었으며 이들은 모두 좁은잎천선과에서 처음으로 분리된 화합물이다. 분리된 화합물에 대한 DPPH 및 ABTS⁺ 라디칼 소거 활성 실험 결과 afzelechin (4) 및 catechin (5)에서 활성이 우수하게 나타났으며 특히 catechin (5)의 경우 대조군인 비타민 C보다 더 좋은 라디칼 소거 활성이 있음을 확인하였다. 또한 HPLC 분석을 통해 좁은잎천선과 잎에서 분리된 catechin의 함량을 확인한 결과 추출물에서 3.8 mg/g, 에틸아세테이트 분획물에서 20.8 mg/g이 함유되어 있는 것으로 확인되었다. 이상의 연구 결과로부터 좁은잎천선과 잎을 이용한 천연 항산화 소재로의 개발이 가능할 것이라 사료된다. In this study, we investigated identification of anti-oxidative constituents from Ficus erecta var. sieboldii King (F. erecta) leaves. DPPH and ABTS⁺ radical scavenging activities were screened for the ethanol extract and solvent fractions, and ethyl acetate fraction showed the most potent scavenging activities. Five constituents were isolated from the ethyl acetate fraction of F. erecta leaves; monoolein (1), oleic acid (2), lutein (3), afzelechin (4), catechin (5). The chemical structures of the isolated compounds were elucidated based on the spectroscopic data including NMR spectra, as well as comparison of the data to the literature values. As far as we know, all of the compounds 1 ∼ 5 were isolated for the first time from this plant. Studies on DPPH and ABTS⁺ radical scavenging activities were conducted for the isolated compounds. Among them, afzelechin (4) and catechin (5) showed strong DPPH and ABTS⁺ radical scavenging activities, whose activities were comparable to a positive control vitamin C. Also, the content of catechin isolated from this plant was determined by HPLC and it was about 3.8 mg/g for the 70% ethanol extract and 20.8 mg/g for the ethyl acetate fraction. From these results, F. erecta leaves extract could be potentially applicable as anti-oxidant ingredients in cosmetic industries.

전신성 홍반성 루푸스 환자에게 혈전증과 항 인지질 항체와의 관계

박성환 ( Sung Hwan Park ),최범순 ( Bum Soon Choi ),조영석 ( Young Suk Cho ),양형인 ( Hyung In Yang ),홍연식 ( Yeon Sik Hong ),이상헌 ( Sang Heon Lee ),조철수 ( Chul Soo Cho ),김호연 ( Ho Youn Kim ) 대한류마티스학회 1996 대한류마티스학회지 Vol.3 No.1

Objective: To investigate the association of antiphosphoilpid antibodies with thrombosis and to evaluate the clinical usefulness of anticardiolipin isotypes measurement in patients with systemic lupus erythematosus (SLE). Methods: We examined the prevalence of IgG, IgM and IgA anticardiolipin antibod (aCL) isotypes measured by ELISA assay and lupus anticoagulant (LA) measured by kaolin clotting time in 158 patients. Results: The prevalence of aCL and their IgM and IgA isotypes were 43.7%, 24.7%, 17.7% and 17.1% respectively. The prevalence of LA was 7.8%. The presence of IgG aCL (81, 81%, odds ratio (OR)=17.55, p<0.001) and LA (45.45%, OR=16.67, p<0.001) were significantly associated with thrombosis. A regression analysis showed that IgG aCL (OR=13.62, p=0.002) and LA (OR=10.59, p=0.002) were also associated with thrombosis. Conclusion: Our results suggest that the detection and serial monitoring of IgG aCL is a useful tool for diagnosis of thrombotic complication due to antiphosholipid antibodies in SLE.

인 제거를 위한 철염 응집시 H2O2첨가에 따른 영향

박성환 ( Sung Hwan Park ),문병현 ( Byung Hyun Moon ) 한국수처리학회 2013 한국수처리학회지 Vol.21 No.6

In this study, the effect of H2O2 addition on ferric coagulation for phosphorus removal. The experiments were conducted under H2O2/Fe molar ratio of 0.4∼6.0; rapid mixing intensity with G value of 500 s-1. The effect of H2O2 injection sequence was investigated also. The characteristics of floc growth were measured by flocculation index (FSI) using the PDA. The removal efficiencies of phosphorus were increased as H2O2/Fe molar ratio increased. However, The removal efficiencies of phosphorus were decreased over the H2O2/Fe ratio 4. Higher removal efficiencies of phosphorus and floc size were observed with sequence dose of ferric coagulant and hydrogen peroxide.

The effect of interleukin-4 on the production of vascular endothelial growth factor in cultured rheumatoid synovial fibroblasts

박성환 ( Sung Hwan Park ),( Chul Soo Cho ),( Mi La Cho ),( So Youn Min ),( Shin Seok Lee ),( Ho Youn Kim ) 대한내과학회 2002 대한내과학회 추계학술발표논문집 Vol.2002 No.2