반복되는 복통과 고혈압을 동반한 급성 간헐성 포르피린증 1예

박미란,서정기,고재성,장주영,양혜란,Park, Mi-Ran,Seo, Jeong-Kee,Ko, Jae-Sung,Chang, Ju-Young,Yang, Hye-Ran 대한소아소화기영양학회 2011 Pediatric gastroenterology, hepatology & nutrition Vol.14 No.1

16세 여아에서 복통, 구토, 고혈압, 경련 및 고지혈증을 보였던 급성 간헐성 포르피린증 1예를 경험하였기에 보고하는 바이다. 소아에서 원인을 알 수 없는 복통에 고혈압, 경련 등 특징적 포르피리아 증상이 동반된 경우에 반드시 급성 간헐성 포르피린증을 고려해야 한다. Acute intermittent porphyria (AIP) is a rare disorder characterized biochemically by the increased excretion of porphyrins and porphyrin precursors, including delta-aminolevulinic acid (ALA) and porphobilinogen (PBG). AIP has variable clinical manifestations, such as acute abdominal pain, vomiting, nausea, constipation, peripheral neuropathy, seizures, tachycardia, and hypertension. A 16-year-old girl presented with recurrent abdominal pain, vomiting, hypertension, seizures, hypercholesterolemia, and red urine. AIP was confirmed by clinical features and increased 24-hour urine ALA and PBG. AIP should be considered in the differential diagnosis of patients who have abdominal pain, hypertension, and seizures when the results of all other tests are normal.

전국민의료보험에 대비한 의무기록분야 관리방안

박미란,Park, Mi-Ran 대한병원협회 1989 대한병원협회지 Vol.18 No.3

실크섬유를 이용한 팬티스타킹 개발에 관한 연구 -실크필라멘트사와 나일론 텍스쳐사 혼방에 따른 스타킹의 물성 및 착용성능 비교-

박미란,조정숙,조길수,Park, Mi-Ran,Jo, Jeong-Suk,Jo, Gil-Su 한국섬유공학회 1995 한국섬유공학회지 Vol.32 No.5

The objectives of this study were 1) to compare physical and wear performances of panty hoses made with silk 61amen1 and texturized nylon filament yams, 2) to examine these characteristics as a function of the percentage of texturized nylon filament yarn, 3) to evaluate thermal resistances and thermoyaphic assessments of those panty hoses worn on a thermal manikin, and 4) to investigate objective wear performances including microclimate and subjective wear sensations and relationships with their physical performances. Five digrent types of panty hoses made with silk filament yarn(S4), texturized nylon filament(N4), and blending level of the two types of yarn were(SIN3, S2N2, S3Nl) used as test specimens. Warmth retention values and Q-max values were measured using Thermo Labo II, and breaking strengths and elongations were evaluated by Instron Tensile Tester. Thermal manikin and subject wear tests were conducted in the following environmental conditions 21$\pm$1$^{\circ}C$, 60$\pm$ 5% RH., and 0.25m/sec air velocity. Ten healthy female subjects followed the repeated exercises consisting of walking on a treadmill and resting. The results were as follows: 1) In warmth retention values and Q-max values, S4 showed higher values than N4. 2) The wickability and moisture regain of S4 showed higher performance than those of N4 but elongation and breaking strength of S4 was lower than that of N4. 3) As the blending level of silk filament yarn increases, warmth retention value, 0-max values, moisture regain, and wickability were increased but elongation and breaking strength were decreased. 4) Clo values measured using thermal manikin increased in the following order: S4>S2N2>N4. 5) Microclimate temperatures of the subjects who worn S4 were significantly higher than those of subjects who worn S2N2 and N4. But microclimate humidities were not significantly different among the subjects who worn S4, S2N2 and N4. 6) Thermal sensation rating of subjects who worn S2N2 was significantly higher than that of subjects who worn S4 and N4. Humidity, tactile and overall sensation ratings of subjects who worn S4 and S2N2 were lower than those of subjects who worn N4.

소아에서 소장형 장중첩증; 자연 정복과 수술적 치료의 비교

박미란,임미선,서정기,고재성,장주영,양혜란,임윤정,김우선,Park, Mi-Ran,Lim, Mi-Sun,Seo, Jeong-Kee,Ko, Jae-Sung,Chang, Ju-Young,Yang, Hye-Ran,Lim, Yoon-Joung,Kim, Woo-Sun 대한소아소화기영양학회 2010 Pediatric gastroenterology, hepatology & nutrition Vol.13 No.2

목 적: 장중첩증은 영아기 급성 복통의 흔한 원인 중 하나로 대부분 특발성의 소장-대장형이다. 반면 소장형 장중첩증은 드물며 시작점을 보이는 경우가 있고 수술적 정복을 필요로하는 경우가 흔하다. 본 연구의 목적은 소아에서 소장형 장중첩증의 임상 양상과 경과에 대해 알아보고자 한다. 방 법: 2005년에서 2010년까지 서울대병원에서 소장형 장중첩증으로 진단받은 21명의 환아들의 임상 양상 및 영상 소견을 후향적으로 분석하였다. 결 과: 임상 양상은 복통 및 보챔(85%), 구토(23%), 발열(14%), 혈변(14%) 및 복부 종괴(4%) 등이었다. 여섯 명(28%)의 환아에서 수술적 치료가 필요하였다. 초음파에서 병변의 직경은 1.6${\pm}$0.7 cm였고 가장자리의 두께는 1.7${\pm}$1.8 mm였다. 열한 명에서 병변이 왼쪽 복부 혹은 배꼽 주위였다. 수술적 치료가 필요했던 환아들은 자연 정복된 환아들에 비해 평균 연령이 높았다(109${\pm}$17개월: 51${\pm}$20개월). 병변의 평균 직경 및 가장 자리의 두께는 수술적 치료가 필요했던 환아들에서 더 큰 소견을 보였고 위치는 두 그룹 간에 차이를 보이지 않았다. 결 론: 소장형 장중첩증은 많은 소아에서 자연 정복된다. 그러나 초음파에서 크기가 크고, 나이가 많을수록 또한 병변의 시작점이 있으면 수술적 치료를 고려할 수 있다. Purpose: Intussusception is one of the most common causes of an acute abdomen in infancy. The majority of pediatric cases of intussusception are of the ileocolic type and usually idiopathic. Small bowel intussusception is rarely diagnosed in children, and few cases have been reported. The purpose of this study was to determine the clinical features and causes of small bowel intussusception in children. Methods: We retrospectively reviewed the clinical and radiologic findings of 21 children with small bowel intussusception who were admitted to Seoul National University Children's Hospital between March 2005 and January 2010. Results: The clinical presentation of small bowel intussusception included abdominal pain or irritability (85%), vomiting (23%), fever (14%), bloody stools (14%), and abdominal masses (4%). Six patients required surgical management. Ultrasonography showed that the mean diameter of the lesions and mean thickness of the outer rims were 1.6${\pm}$0.7 and 1.7${\pm}$1.8 mm, respectively. Eleven lesions were located in the left abdominal or paraumbilical regions. Children who underwent surgical management were older than children with transient small bowel intussusception (mean age, 51 vs. 109 months). The mean diameter of the lesions and mean thickness of the outer rims were greater in the surgically-managed group. The location of intussusception was not significantly different between the two groups. Conclusion: Small bowel intussusception was spontaneously reduced in a large number of pediatric patients. However, sonographic demonstration of larger size, older age, and pathologic lead point warrant surgical intervention.

병원경영 효율화와 의무기록 대처방안

박미란,Park, Mi-Ran 대한병원협회 1997 대한병원협회지 Vol.26 No.4

Drug reaction with eosinophilia and systemic symptoms 증후군의 임상 양상과 혈청 비타민 D 측정치 사이의 연관성

박미란 ( Mi Ran Park ),남영희 ( Young Hee Nam ),정일환 ( Il Hwan Jeong ),이혜원 ( Hye Won Lee ),김용준 ( Yong Jun Kim ),박인철 ( In Chul Park ),조덕송 ( Duk Song Cho ),윤늘봄 ( Neul Bom Yoon ),엄수정 ( Soo Jung Um ),손춘희 ( Choon 대한소아알레르기호흡기학회 1991 소아알레르기 및 호흡기학회지 Vol.1 No.2

Purpose: Vitamin D deficiency (VDD) is widely spread and on the increase throughout the world. Although vitamin D is essential for skeletal mineralization, VDD or vitamin D insufficiency (VDI) has been associated with nonskeletal disorders including cardiovascular disease, cancer, allergic disease and skin disease. However, a few reports showed the association of vitamin D and drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. Thereafter, we evaluated the association between vitamin D and DRESS syndrome. Methods: We conducted a retrospective study on 45 patients with DRESS syndrome. Four hundred and ninty-eight healthy people who visited the health screening center were enrolled in the study as a control group. We investigated the clinical characteristics, the causative drugs and treatments in the patients with DRESS syndrome, and also analyzed the associations with serum 25-hydroxyvitamin D (25(OH)D3). Results: Forty-four patients (97.8%) had low serum vitamin D levels; 21 patients were VDD (serum 25(OH)D3 <10 ng/mL), and 23 patients were VDI (serum 25(OH)D3 10 to 30 ng/mL). There were no significant differences in clinical parameters between two groups. Serum 25(OH)D3 level of the study patients was significantly lower that of the controls (12.3±9.6 ng/mL vs. 17.3±5.5 ng/mL, P<0.001). Serum 25(OH)D3 level showed a significant negative correlation with admission days (r=-0.377, P=0.011). Conclusion: The majority of the patients with DRESS syndrome showed low vitamin D levels. Serum 25(OH)D3 was inversely correlated with admission days. (Allergy Asthma Respir Dis 2013;1:144-150)

생물학적 처리공정을 거친 돈사폐수의 영양염류 제거를 위한 Duckweed ( Lemna Species ) 의 이용 및 생장특성 ( I )

박미란(Mi Ran Park),김병욱(Byoung Ug Kim),임재영(Jay Myoung Rim) 한국물환경학회 2000 한국물환경학회지 Vol.16 No.5

This study was performed to investigate nutrient removal characteristics of swine wastewater using duckweed as floating aquatic plant, and growth characteristics of duckweed with retention time. As the result of experiments. nutrient removal efficiency was very high in a retention time of 3 days, and was more than 90 % on the all operation conditions in a retention time of 10 days. Growth rate was most effected by the change of retention time. Growth rate was very high as 0.280 day^(-1) in a retention time of 3 days. Growth rate decreased gradually as retention time increased, so it was very low as 0.084 day^(-1) when a retention time was 10 days. Crude protein content was very high with ranges of from 23.9 % to 37.6 % as dry content during operating periods. Consequently, duckweed can be used to treat the swine wastewater and its biomass can be used for the alternative protein source as animal food, very effectively.

홀아비꽃대(Chloranthus japonicus) 뿌리로부터 분리한 shizukanol들의 생물활성

박미란(Mi Ran Park),김혜영(Hae Young Kim),최경자(Gyung Ja Choi),이선우(Seon-Woo Lee),장경수(Kyoung Soo Jang),김진석(Jin-Seog Kim),홍경식(Kyung-Sik Hong),박노중(No-Joong Park),조광연(Kwang Yun Cho),김진철(Jin-Cheol Kim) 한국농약과학회 2004 농약과학회지 Vol.8 No.4

The methanol extract of Chloranthus japonicus roots effectively controlled the development of rice blast(Magnaporthe grisea), rice sheath blight(Corticium sasaki), tomato gray mold(Botrytis cinerea), tomato late blight(Phytophthora infestans), and wheat leaf rust(Puccinia recondita). From the methanol extract of C. japonicus roots, three antifungal substances were isolated. Their chemical structures were determined to be shizukanols B, C, and D mainly by mass and NMR spectral data. Among the three substances, shizukanol C showed the strongest inhibitory activity against mycelial growth of the plant pathogenic fungi tested; it completely inhibited mycelial growth of M. grisea, Colletotrichum gloeosporioides, and C. acutatum at concentrations of more than 12.5 ㎍/ and P. infestans at concentrations of more than 3.13 ㎍/㎖. They also controlled effectively the development of rice blast and wheat leaf rust. On the other hand, they caused phytotoxic symptoms on barley leaves and inhibited the growth of duckweed (Lemna paucicostata) with EC?? values of 30.0 ㎍/㎖ for shizukanol B, 49.9 ㎍/㎖ for shizukanol C, and 154 ㎍/㎖ for shizukanol D. In addition, shizukanol C showed an insecticidal activity against brown planthopper (Nilaparavata lugens), green peach aphid (Myzus persicae), diamond-back moth (Plutella xylostella), and tobacco cutworm (Spodoptera litura) of the 5 arthropod pests tested with mortality values of more than 60% at a concentration of 1,000 ㎍/㎖.

부산, 경남, 경북지역 치과 병ㆍ의원에 근무하는 치과위생사의 직무만족도 관련요인

박미란 ( Mi Ran Park ),이정화 ( Jung Hwa Lee ) 대한구강보건학회 2016 大韓口腔保健學會誌 Vol.40 No.3

Objectives: This study was aimed at seeking an effective method of improving job satisfaction and practice performance of clinical dental hygienists by analyzing their job satisfaction factors. Methods: Questionnaires were distributed to 210 clinical dental hygienists working at dental institutions in Busan, Gyeongnam, and Gyeongbuk, from the 25th of July through to the 30th of August, 2015, after receiving approval of the Institutional Review Board. The following conclusions were derived as a result of analyzing a total of 198 of the 210 questionnaires, 12 of which were excluded due to non-response or suspicious authenticity. Results: Analysis of the job satisfaction according to the participants’ general characteristics revealed significant differences in terms of marital status (P<0.001), age (P<0.001), education (P=0.002), income (P<0.001), and total work experience (P<0.001). Further, groups showing high scores on the internal marketing system, structural factors, communication system factors, and compensation factors had higher job satisfaction (P<0.01). Analysis of oral health education, a factor in the job satisfaction related to practice performance, was carried out by the high group. This led to high satisfaction with professional pride (P<0.01) and patient relationships (P<0.01). Preventive treatment, another factor in job satisfaction related to practice performance, led to high satisfaction with colleague relationships (P<0.05). The job satisfaction for medical cure cooperation tasks showed no significant differences. Administration and management tasks for high groups led to higher satisfaction with professional pride, ability to work, work environment, compensation, and patient relationships (P<0.01). Conclusions: These results show the need for an expansion in oral health education and preventive treatment tasks in order to ensure greater job satisfaction in dental hygienists. Additionally, the development of internal marketing systems within dental care institutions is necessary to further enhance and promote a sense of accomplishment at work.

휴대용 멀티미디어기기를 위한 RAW 이미지 포맷 분석 및 응용

박미란(Park, Mi-Ran),신소희(Sin, So-Hee),김재신(Kim, Jae-Shin),노광현(Ro, Kwang-Hyun) 한국산학기술학회 2009 한국산학기술학회 학술대회 Vol.- No.-

본 논문에서는 RAW 이미지 포맷 중 PEF, MRW에 대한 분석 결과와 RAWImage Viewer에 대해 소개한다. DSLR 디지털 카메라로 촬영되는 이미지 파일은 범용의 JPEG 포맷이나 제조사별 독자적인RAW 이미지 포맷으로 저장된다. 이러한 RAW 이미지 파일을 PMP 등의 휴대용 멀티미디어 기기나디지털액자에서 재생 및 확인하기 위한 요구가 증대되고 있다. 하지만, RAW 이미지 포맷이 디지털카메라 제조사별로 다르고, 해당 포맷에 대한 구체적인 정보가 공개되지 않아 대부분의 휴대용 멀티미디어 기기에서 RAW 이미지 파일 재생 기능을 완벽하게 지원하지 못하고 있다. 본 논문에서는 RAW이미지 파일 포맷을 분석하여 다양한 임베디드 멀티미디어 기기에서 모든 RAW 이미지 파일을 지원할 수 있는 라이브러리 구축을 위한 연구 결과 중 일부를 소개한다. Cannon의 CRW, CR2 포맷과Nikon의 NEF 분석 결과에 이어 PEF, MRW에 대한 분석 결과와 RAW 이미지 출력 및 분석 기능이포함된 RAWImage Viewer에 대해 설명한다. 연구 결과는 RAW 파일을 재생할 수 있는 임베디드 장비 및 PC용 RAW 이미지 파일 재생 라이브러리를 구축 및 응용 프로그램 개발시 활용될 것이다.