난소의 자궁내막양선암 3례

문창환,서병희,목정은,박용구,지현숙,이중달 慶熙大學校 醫科大學 1983 慶熙 醫大 論文集 Vol.8 No.1

정상중기임신 및 신경관 결손 태아를 가진 임신의 양수내 Alfa-fetcprotein 치에 관한 연구

문창환,주갑순 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.7

비전이성 융모성종양의 임상적 고찰

문창환,서병희,목정은,이재현 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.8

특발성 후복막섬유증 1례

문창환,김승보,오보훈,이재현 慶熙大學校 醫科大學 1982 慶熙 醫大 論文集 Vol.7 No.1

북한 핵미사일 위협과 한미동맹의 과제 (예상쟁점 및 대응방향 중심으로)

문창환 ( Moon Chang-hwan ) 한국군사학회 2017 군사논단 Vol.92 No.-

The purpose of this article is to analyze the change of U.S. policy and to suggest implications for the Republic of Korea. The alliance between the Republic of Korea and the United States has been firmly maintained more than 60 years and it is the solid foundation that effectively protects the Republic of Korea from the North Korea threats. However, North Korea's nuclear capabilities have been seriously increased in the previous administration. Therefore, it is highly emphasized that the U.S.-KOR. alliance should find new steps to stop North Korea's misconducts before North Korea cross the redline. The leadership change might trigger some potential issues because each country has different interests. This paper will be mentioned two latent issues and policy recommendations such as cost-sharing, wartime OPCON transfer and USFK's withdrawal.

Dobutamine-Induced Perioperative Anaphylaxis in a Dog

정영은,장윤설,문창환,정재민,노윤호,이해범,정성목 한국임상수의학회 2020 한국임상수의학회지 Vol.37 No.3

A 9-years old spayed female Maltese was referred for the treatment of mass on the right 1st mammary gland and acute weight bearing lameness of right hindlimb. It was diagnosed as malignant mammary tumor and cranial cruciate ligament rupture of right stifle joint. Right upper regional mastectomy followed by cranial closing wedge osteotomy (CCWO) of the right tibia were planned for the present problems. Preanesthetic work-up did not show any remarkable abnormalities. Forty-five minutes after induction of anesthesia dobutamine was administered at a rate of 5 μg/kg/min by constant rate infusion due to gradual decrease of blood pressure below MAP 60 mmHg during surgical procedure. Despite of the increase of dobutamine infusion rate up to 20 μg/kg/min, blood pressure didn’t recover. At the end of regional mastectomy generalized skin redness and eyelid edema were identified. Anesthesia was stopped and CCWO procedure was cancelled. To recover from the anaphylactic reactions dexamethasone and diphenhydramine were administered. After about one hour, the patient completely recovered from hypotension and anaphylactic reactions. After 4 weeks, intradermal skin test (IDST) was performed for all the drugs used during anesthesia. Only dobutamine showed positive reaction in IDST. Therefore, dobutamine was considered as the causative agent of anaphylaxis in this patient during the anesthesia. In case of perioperative anaphylactic reaction, postoperative investigation should be performed to identify causative agent and to provide safe recommendations for future anesthetic procedure.

수소경제사회 실현을 위한 액체 유기 수소캐리어를 이용한 수소 수송 관련 예비 경제성 평가

이보름,이현준,문창환,문상봉,임한권 한국수소및신에너지학회 2019 한국수소 및 신에너지학회논문집 Vol.30 No.2

Reliable H2 supply is necessary for entering a H2 society. Among the various H2 storage and transportation methods, liquid organic H2 carrier (LOHC) is in the spotlight because of a lot of advantages compared to conventional one such as compressed H2 and liquefied H2. Therefore, we performed preliminary economic analysis of H2 supply cost using LOHC for a H2 production capacity of 300 Nm3 h-1 employing itemized cost estimation and sensitivity analysis to evaluate economic viability of this technology in Korea.

PEM 수전해를 이용한 P2G에 대한 경제적 타당성 분석

정선주,최낙헌,문창환,문상봉,임한권 한국수소및신에너지학회 2017 한국수소 및 신에너지학회논문집 Vol.28 No.3

With worldwide efforts to increase the portion of renewable energy for CO2 reductions, a lot of attention has been paid to P2G (power-to-gas) in Europe and Japan to efficiently utilize the surplus electricity. In this paper, economic feasibility analysis has been carried out for P2G using PEM water electrolysis by reflecting current economic status in Korea. In addition, efficiency and electricity price required to be competent in Korean market were provided. Based on cash flow diagrams, unit production costs for H2 and CH4 were estimated and profitability of P2G using PEM water electrolysis was analyzed.

Anesthetic Effect of Different Ratio of Ketamine and Propofol in Dogs

이목현,김소희,문창환,박지영,이해범,정성목 韓國臨床獸醫學會 2017 한국임상수의학회지 Vol.34 No.4

Use of ketamineand propofol combination (so-called Ketofol) anesthesiain a fixed ratio (1:1 mg/ml) was reported in dogs. The use of ketofol reduced cardiovascular suppression, but respiratory-related side effects was not significantly different from propofol alone. In this study, we evaluated the quality of ketofol anesthesia and changesin cardiopulmonary function according to the ratio of ketamine to propofol. The experimental groups were divided into three groups: propofol alone (P group), 3:7 ketofol group (PK1 group) and 1:1 ketofol group (PK2). For each group, the dose of 0.8 ml/kgwas administered intravenously at a constant rate until the tracheal intubation was possibleand anesthesia was maintained with isoflurane for 120 minutes after induction of anesthesia. There was no significant difference in the anesthetic quality among three groups. Also, there was no difference in respiratory rate, tidal volume, end-tidal carbondioxide, and oxygen saturation. In group P, heart rate was not changed significantly during anesthesia, but arterial blood pressure decreased, while heart rate and arterial blood pressure increased significantly in group PK2. In the PK1 group, heart rate and arterial blood pressure during anesthesia remained similar to pre-anesthetic values. In conclusion, ketofol might be used as induction agent, and 3:7 ratioof ketofol showed more safe and effective anesthetic effect in dogs. Additionally, 1:1 ketofol may be used in patients with severe bradycardia orhypotension with close monitoring during anesthesia.

체외수정에서 수정에 따른 난포액내 호르몬의 동태

이재현,서병희,홍진기,문창환,김재명 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.3

난포액내의 호르몬동태가 난자의 성숙유무 및 수정여부에 미치는 영향을 알기 위하여 FSH/HMG/hCG 를 이용한 경희체외수정프로그램의 12예의 수정 및 임신이 된 군(제I군)과 14예의 수정이 전혀 이루어지지 않은 군(제 II군)에서 각각 채취된 53개와 61개의 난포액내 FSH, LH, P4, b-endorphin, b-hCG를 측정하여 다음과 같은 결론을 얻었다. 1. 제 I군과 제 II군에서의 시술당 난자채취수는 각각 3.3개, 2.9개였다(p$lt;0.05). 2. 제 I군과 제 II군에서 hCG투여일의 혈중 E2치는 각각 2207.6, 2735.4 ng/ml으로서 I군이 약간 높았다. 3. hCG 투여일에 혈중 E2치가 1,200 pg/ml일때 제 I군과 제 II군의 난포액내 FSH, LH, prolactin, b-endorphin, b-hCG치에서 차이가 있었으나(p$lt;0.01) E2, P4, E2/P4치는 차이가 없었다(p$lt;0.01). 그러나 혈중 E2치가 1,200 pg/ml이상일때 제 I군과 제 II군에서 E2, prolactin치는 차이가 있었다(p$lt;0.01). 4. 난포액의 양에 따라 제 I군과 제 II군에서 난포액이 2-4 ml일때 LH, Prolactin, b-endorphin치는 차이가 있었다(p$lt;0.05). 또 LH, b-endorphin치는 제 II군보다 높은 수치를 나타낸 반면 prolactin치는 낮았다(제 I군: 제 II군, LH: 28.2 : 15.6 mI.U./ml, prolactin; 28.7 : 40.0 ng/ml, b-endorphin, 2.6 : 1.4 pM/ml)난포액이 5 ml이상인 경우 제 I군과 제 II군의 E2치는 차이가 있었다(p$lt;0.005). 5. 제 I군으로 부터 채취된 난자는 성숙란이 32개, 미성숙란이 5개인 반면, 제 II군의 난자는 성숙란이 19개, 미성숙란이 21개였다. 성숙된 난자를 함유하고 있는 난포액내의 E2, b-hCG치는 미성숙란의 경우보다 높은 수치를 나타냈으나(p$lt;0.05), P4, FSH, LH, endorphin 및 E2/P4 치는 통계적인 유의성이 없었다. 6. 일반적으로 난포액내 LH, b-endorphin, b-hCG와 androstenedione치는 제 I군에서 더 높았다(p$lt;0.05). 그러나 이들 호르몬치와 난자의 성숙도사이의 상관관계는 없었다. The growth of ovarian follicle is affected by endocrinologic regulation by Hypothalamic-Pituitary-Ovarian axis and intrafollicular endocrinologic environment. 26 treatment cycles were studied in 24 patients who were treated by Kyung Hee In vitro fertilization program and HMG/hCG or FSH/HMG/hCG were used for ovarian stimulation. Twelve cases who achieved fertilization and pregnancy were fallen into group I and 14 cases who had not fertilized were fallen into group II. Among the apsirated follicles, the 53 follicular fluids in group I and 61 follicular fluids in group II were included in this study and the others were excluded due to possible contamination by flushing medium. In present study, author measured the concentrations of estrogen, progesterone, FSH, LH, b-endorphin, b-hCG, prolactin, androstenedione by radioimmunoassay in follicular fluid obtained from undergoing ovum aspiration from January 1990 to June 1990. The results obtained in this study were summarized as follows; 1. The number of aspirated ova were 3.3 /cases in group I and 2.9 cases in group II. In group I, mature oocytes were 33 and immature oocytes were 7 and in group Ii, mature oocytes were 19 and immature oocytes wer 21. 2. On the day of hCG injection, serum estradiol level was 2207.6 pg/ml in group I and 1735.4 pg/ml in group II. 3. As a whole, intrafollicular estradiol level was higher in pregnant group than in not-fertilized group(P$lt;0.05), and the follicles containing mature oocytes had higher estradiol level than the follicles containing immaure oocytes(P$lt;0.05). 4. Intrafollicular progesterone level was higher in not-fertilized group and in the follicles containing immature oocytes but there was no statistical difference and intrafollicular prolactin level was also higher in not-fertilized group(p$lt;0.05) and immature follicles. 5. In general, intrafollicular LH, b-endorphin, b-hCG and androstenedione levels were higher in pregnant group(p$lt;0.05), but the relations between the hormonal level and maturity of oocyte was not existed. 6. As the follicular volume increases, intrafollicular progesterone level was also increased(P$lt;0.05), but other hormones did not show relationship between follicular size and their level.