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만성신부전으로 의심되는 환자의 보중익기탕(補中益氣湯) 및 가미방(加味方) 투여 호전례
남우진,배수현,박선영,정소연,박동일,Nam, Woo-Jin,Bae, Su-Hyun,Park, Sun-Young,Jung, So-Youn,Park, Dong-Il 대한한의학방제학회 2013 大韓韓醫學方劑學會誌 Vol.21 No.2
Objectives : The purpose of this study is to report the clinical effect of herbal medicine on the patient considering chronic renal failure. The patient complained of hemiparesis, general weakness, anorexia, nausea and dizziness. Methods : According to the traditional Korean medicine syndrome differentiation, the patient was classified as Deficiency of Spleen Qi and prescribed Bojungikki-tang and Bojungikki-tang gamibang as well as acupuncture and moxibustion treatment. Changes of BUN, creatinine, VAS for genaral weakness, nausea, dizziness were compared before and after treatment for 2 weeks. Results : After treatment, the level of BUN and creatinine was decreased and main symptoms were improved. Conclusions : Herbal medicine Bojungikki-tang and Bojungikki-tang gamibang with acupuncture and moxibustion treatment would be efficient to the patient of chronic renal failure.
Colistin 투여 중 발생한 급성 신손상의 임상적 의의
남우진 ( Woo Jin Nam ),신정호 ( Jung Ho Shin ),한민지 ( Min Jee Han ),박윤수 ( Youn Su Park ),김수현 ( Su Hyun Kim ),오동진 ( Dong Jin Oh ),유석희 ( Suk Hee Yu ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.5
Purpose: Colistin (colistimethate sodium) became available for clinical use in 1959 and was used until the early 1980s to treat infections caused by Gram-negative rods. It was abandoned during the last two decades mainly due to its significant nephrotoxicity. However, the emergence of multidrug-resistant (MDR) bacteria such as Pseudomonas aeruginosa and Acinetobacter baumanii has resulted in significantly increased use of intravenous colistin. This study was designed to investigate the incidence and risk factors of acute kidney injury (AKI) associated with intravenous colistin (colistimethate sodium) treatment. Methods: We retrospectively collected the data from patients who were admitted to Chung-Ang University Hospital and treated with colistin from May 2007 to June 2009. Among these, we excluded the patients with baseline glomerular filtration rate (GFR) less than 15 ml/min/1.73m2. AKI was defined as an increase of creatinine more than 150% from the baseline, according to RIFLE criteria. Results: A total of 92 patients met the inclusion criteria and were included in the analysis. AKI occurred in 43 (47%) of the 92 patients. The cumulative doses (2.51±1.89 vs. 1.75±1.35 g, p=0.032) of colistin were significantly greater in the AKI group than in the normal kidney function (NKF) group. Serum creatinine level showed a significant increase in the AKI group, from day 3 (1.6±1.1 vs. 0.9±0.5 mg/dL, p=0.001) to day 90 (2.1±1.9 vs. 0.7±0.2 mg/dL, p=0.033). Furthermore, the occurrence of AKI at day 3 was a significant predictor of shorter survival (Log rank test p=0.031). Conclusion: AKI was a relatively common side effect of colistin. The cumulative dose was critical, rather than the daily dose or duration of treatment. Early acute kidney injury may predict shorter cumulative survival in patients undergoing colistin treatment.
한승목,남우진,이성수,Han, Seung-Mok,Nam, Woo-Jin,Lee, Seongsoo 한국전기전자학회 2013 전기전자학회논문지 Vol.17 No.2
본 논문에서는 차세대 동영상 압축 표준인 HEVC의 핵심 프로세스 중 하나인 코어 변환기를 설계하고 이를 합성한 후 검증하였다. 제안하는 코어 변환기는 면적을 많이 차지하는 곱셈기 대신에 덧셈기와 쉬프터만을 사용하였으며, 쉬프터도 실제로는 와이어 연결과 멀티플렉서만을 사용하여 면적을 크게 줄였다. 또한 하나의 하드웨어로 $4{\times}4$에서 $16{\times}16$ 블록까지 모두 처리할 수 있도록 설계하였으며, 이를 위해서 연산처리기를 재사용하는 아키텍쳐를 제안하였다. 0.13um 공정으로 설계된 코어 변환기는 $16{\times}16$ 블록을 2-D 변환 처리하는데 160 사이클이 소요되며 게이트 수는 101,015 게이트이다. This paper proposes and implements an core transform architecture, which is one of the major processes in HEVC video compression standard. The proposed core transform architecture is implemented with only adders and shifters instead of area-consuming multipliers. Shifters in the proposed core transform architecture are implemented in wires and multiplexers, which significantly reduces chip area. Also, it can process from $4{\times}4$ to $16{\times}16$ blocks with common hardware by reusing processing elements. Designed core transform architecture in 0.13um technology can process a $16{\times}16$ block with 2-D transform in 130 cycles, and its gate count is 101,015 gates.
설색의 분포 및 설색과 임상병리검사 결과의 연관성에 대한 연구
임제민,남우진,윤용재,이상민,강유경,김원일,Yim, Je-Min,Nam, Woo-Jin,Yun, Yong-Jae,Lee, Sang-Min,Kang, You-Gyung,Kim, Won-Il 대한한방내과학회 2013 大韓韓方內科學會誌 Vol.34 No.1
Objectives : The aim of this study was to evaluate the distribution of tongue color and the correlation of the tongue colors with clinical laboratory parameters. Methods : Statistical analysis on the frequency of each tongue color and the results of the clinical laboratory parameters in each tongue color group. Results : Tongue colors that appeared most frequently were 702c, 695c, 493c, 694c, 701c, 500c, 7432c, 7431c, 7634c, 7419c in that order. Following them, 494c and 507c were rarer colors, and 501c, 673c, 687c, 693c, 696c, 703c, 7418c were equally rarest colors. Among each tongue color group, a significant difference was found in the result of complete blood cell count (CBC). The level of red blood cell (RBC) of 7432c group was significantly higher than that of the other groups except 694c group. The level of hemoglobin (Hb), hematocrit (Hct) of 7432c group were significantly higher than those of all the other groups. The level of RBC of 7431c group was lowest and significantly different from 694c, 7432c group. In results of the other tests were not significantly different. However the level of total cholesterol was higher in 695c, 694c, 500c group, and the level of triglyceride was higher in 500c, 7431c, 694c group. Those four colors have a low chroma and 7431c, 695c take blue violet color. Conclusions : The tongue color is distributed throughout following colors by order of frequency: 702c, 695c, 493c, 694c, 701c, 500c, 7432c, 7431c, 7634c, 7419c, 708c, 494c, 507c, 501c, 673c, 687c, 693c, 696c, 703c, 7418c. Some parameters of CBC has a significant correlation with some tongue colors. Other results including lipid profile, renal function test, and liver function test had no significant difference according to tongue color. However, the colors which have low chroma or take blue violet color tented to be higher in the levels of total cholesterol and triglyceride.